Papers/PMID:16855957
Calcium supplementation during pregnancy for preventing hypertensive disorders and related problems.
The Cochrane database of systematic reviews2006The record
2 findings · 1 compound · 2 endpoints · 1 null
What it reported
How to read these marksWhat moved
1 finding
Ca(2+) — decreases pre-eclampsia incidence
Evidence strength: very limited.Findingreplicated ×4“There was also a reduction in the risk of pre-eclampsia associated with calcium supplementation (12 trials, 15,206 women: RR 0.48, 95% CI 0.33 to 0.69).”
Quoted verbatim from Calcium supplementation during pregnancy for preventing hypertensive disorders and related problems.. - Study
- meta-analysis
- Participants
- 15,206
- Dose
- at least one gram daily during pregnancy
- Population
- Pregnant women in 12 randomised trials of at least one gram daily of calcium versus placebo
Effect 0.48 risk ratio, 95% CI 0.33 to 0.69
Calcium supplementation during pregnancy for preventing hypertensive disorders and related problems.2006PMID:1685595710.1002/14651858.CD001059.pub2Permalink
What did not
1 finding
Ca(2+) — no detected effect on preterm birth incidence
Evidence strength: very limited.FindingNull resultreplicated ×2“There was no overall effect on the risk of preterm birth (10 trials, 14,751 women: RR 0.81, 95% CI 0.64 to 1.03), or stillbirth or death before discharge from hospital (10 trials 15,141 babies; RR 0.89, 95% CI 0.73 to 1.09).”
Quoted verbatim from Calcium supplementation during pregnancy for preventing hypertensive disorders and related problems.. - Study
- meta-analysis
- Participants
- 14,751
- Dose
- at least one gram daily during pregnancy
- Population
- Pregnant women in 10 randomised trials of at least one gram daily of calcium versus placebo
Effect 0.81 risk ratio, 95% CI 0.64 to 1.03
Calcium supplementation during pregnancy for preventing hypertensive disorders and related problems.2006PMID:1685595710.1002/14651858.CD001059.pub2Permalink