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4,601–4,650 of 12,877 reactions from Human-GEM
(R)-4-phosphopantothenoyl-cysteine[c] + ADP[c] + H+[c] = ATP[c] + N-pantothenoylcysteine[c]
ReversibleBalancedEC 2.7.1.33Pantothenate and CoA metabolismHuman-GEM MAR04730
(R)-4-phosphopantothenoyl-cysteine[m] + ADP[m] + H+[m] = ATP[m] + N-pantothenoylcysteine[m]
ReversibleBalancedEC 2.7.1.33Pantothenate and CoA metabolismHuman-GEM MAR04731
dephospho-CoA[c] + H2O[c] = AMP[c] + 2 H+[c] + phosphopantetheine[c]
Left to rightBalancedEC 3.6.1.9Pantothenate and CoA metabolismHuman-GEM MAR04732
(R)-4-phosphopantothenoyl-cysteine[m] + H+[m] = CO2[m] + phosphopantetheine[m]
Left to rightBalancedEC 4.1.1.36Pantothenate and CoA metabolismHuman-GEM MAR04733
ATP[m] + H+[m] + phosphopantetheine[m] = dephospho-CoA[m] + PPi[m]
Left to rightBalancedEC 2.7.7.3Pantothenate and CoA metabolismHuman-GEM MAR04734
acrylyl-CoA[m] + H2O[m] = 3-hydroxypropionyl-CoA[m]
ReversibleBalancedEC 4.2.1.17Beta-alanine metabolismHuman-GEM MAR04735
dihydrothymine[c] + H2O[c] = 3-ureidoisobutyrate[c] + H+[c]
Left to rightBalancedEC 3.5.2.2Pyrimidine metabolismHuman-GEM MAR04736
2-aminoadipate 6-semialdehyde[c] + H2O[c] + NAD+[c] = 2 H+[c] + L-2-aminoadipate[c] + NADH[c]
Left to rightBalancedEC 1.2.1.31Lysine metabolismHuman-GEM MAR04737
2-aminoadipate 6-semialdehyde[c] + L-2-aminoadipate[m] = 2-aminoadipate 6-semialdehyde[m] + L-2-aminoadipate[c]
ReversibleBalancedTransportTransport reactionsHuman-GEM MAR04738
2-aminoadipate 6-semialdehyde[m] + H2O[m] + NAD+[m] = 2 H+[m] + L-2-aminoadipate[m] + NADH[m]
Left to rightBalancedEC 1.2.1.31Lysine metabolismHuman-GEM MAR04739
1-piperideine-6-carboxylate[c] + H+[c] + H2O[c] = 2-aminoadipate 6-semialdehyde[c]
ReversibleBalancedEC 1.14.17.1Lysine metabolismHuman-GEM MAR04740
3-hydroxypropionyl-CoA[m] + H2O[m] = CoA[m] + H+[m] + hydracrylate[m]
Left to rightBalancedEC 3.1.2.4Propanoate metabolismHuman-GEM MAR04741
glycine[m] + H+[m] + succinyl-CoA[m] = 5-aminolevulinate[m] + CO2[m] + CoA[m]
Left to rightBalancedEC 2.3.1.37Glycine, serine and threonine metabolismHuman-GEM MAR04742
5-aminolevulinate[c] = 5-aminolevulinate[m]
ReversibleBalancedTransportTransport reactionsHuman-GEM MAR04743
2 5-aminolevulinate[c] = H+[c] + 2 H2O[c] + porphobilinogen[c]
Left to rightBalancedEC 4.2.1.24Porphyrin metabolismHuman-GEM MAR04744
L-carnitine[c] + adipoyl-CoA[c] = CoA[c] + Adipoyl Carnitine[c]
ReversibleBalancedEC 2.3.1.21Fatty acid oxidationHuman-GEM MAR04745
H2O[c] + 4 porphobilinogen[c] = 4 H+[c] + hydroxymethylbilane[c] + 4 NH3[c]
Left to rightBalancedEC 2.5.1.61Porphyrin metabolismHuman-GEM MAR04746
hydroxymethylbilane[c] = H2O[c] + uroporphyrinogen III[c]
Left to rightBalancedEC 4.2.1.75Porphyrin metabolismHuman-GEM MAR04748
L-carnitine[c] + octenoyl-CoA[c] = CoA[c] + Octenoyl Carnitine[c]
ReversibleBalancedEC 2.3.1.21Fatty acid oxidationHuman-GEM MAR04749
4 H+[c] + uroporphyrinogen III[c] = 4 CO2[c] + coproporphyrinogen III[c]
Left to rightBalancedEC 4.1.1.37Porphyrin metabolismHuman-GEM MAR04750
coproporphyrinogen III[c] + 2 H+[c] + O2[c] = 2 CO2[c] + 2 H2O[c] + protoporphyrinogen IX[c]
Left to rightBalancedEC 1.3.3.3Porphyrin metabolismHuman-GEM MAR04752
protoporphyrinogen IX[c] = protoporphyrinogen IX[m]
Left to rightBalancedTransportTransport reactionsHuman-GEM MAR04754
3 O2[m] + protoporphyrinogen IX[m] = 3 H2O2[m] + protoporphyrin[m]
Left to rightBalancedEC 1.3.3.4Porphyrin metabolismHuman-GEM MAR04755
protoporphyrin[c] = protoporphyrin[m]
ReversibleBalancedTransportTransport reactionsHuman-GEM MAR04756
3 O2[c] + protoporphyrinogen IX[c] = 3 H2O2[c] + protoporphyrin[c]
Left to rightBalancedEC 1.3.3.4Porphyrin metabolismHuman-GEM MAR04757
L-carnitine[c] + suberyl-CoA[c] = CoA[c] + Suberyl Carnitine[c]
ReversibleBalancedEC 2.3.1.21Fatty acid oxidationHuman-GEM MAR04759
heme[c] = heme[m]
ReversibleBalancedTransportTransport reactionsHuman-GEM MAR04760
apocytochrome-C[m] + heme[m] = cytochrome-C[m]
Left to rightBalancedEC 4.4.1.17Porphyrin metabolismHuman-GEM MAR04762
3 FADH2[c] + 2 H+[c] + hemoglobin[c] + 3 O2[c] = biliverdin[c] + CO[c] + 3 FAD[c] + Fe3+[c] + globin[c] + 3 H2O[c]
Left to rightUnbalancedEC 1.14.14.18Porphyrin metabolismHuman-GEM MAR04763
biliverdin[c] + H+[c] + NADH[c] = bilirubin[c] + NAD+[c]
Left to rightBalancedEC 1.3.1.24Porphyrin metabolismHuman-GEM MAR04764
bilirubin[c] = bilirubin[r]
ReversibleBalancedTransportTransport reactionsHuman-GEM MAR04765
bilirubin[r] + 2 UDP-glucuronate[r] = bilirubin-bisglucuronoside[r] + 2 UDP[r]
Left to rightBalancedEC 2.4.1.17Steroid metabolismHuman-GEM MAR04766
bilirubin[r] + bilirubin-bisglucuronoside[r] = 2 bilirubin-monoglucuronoside[r]
Left to rightBalancedROS detoxificationHuman-GEM MAR04767
6 H+[c] + uroporphyrin III[c] = uroporphyrinogen III[c]
ReversibleUnbalancedPorphyrin metabolismHuman-GEM MAR04768
6 H+[c] + uroporphyrin I[c] = uroporphyrinogen III[c]
ReversibleUnbalancedPorphyrin metabolismHuman-GEM MAR04769
coproporphyrin III[c] + 6 H+[c] = coproporphyrinogen III[c]
ReversibleUnbalancedPorphyrin metabolismHuman-GEM MAR04770
H2O[c] + uroporphyrinogen I[c] = hydroxymethylbilane[c]
ReversibleBalancedPorphyrin metabolismHuman-GEM MAR04771
4 H+[c] + uroporphyrinogen I[c] = 4 CO2[c] + coproporphyrinogen I[c]
Left to rightBalancedEC 4.1.1.37Porphyrin metabolismHuman-GEM MAR04772
coproporphyrin I[c] + 6 H+[c] = coproporphyrinogen I[c]
ReversibleUnbalancedPorphyrin metabolismHuman-GEM MAR04773
AKG[c] + O2[c] + proline[c] = CO2[c] + succinate[c] + trans-4-hydroxy-L-proline[c]
Left to rightBalancedEC 1.14.11.2Arginine and proline metabolismHuman-GEM MAR04776
AKG[m] + O2[m] + proline[m] = CO2[m] + succinate[m] + trans-4-hydroxy-L-proline[m]
Left to rightBalancedEC 1.14.11.2Arginine and proline metabolismHuman-GEM MAR04777
NAD+[c] + trans-4-hydroxy-L-proline[c] = 2 H+[c] + L-1-pyrroline-3-hydroxy-5-carboxylate[c] + NADH[c]
Left to rightBalancedEC 1.5.1.2Arginine and proline metabolismHuman-GEM MAR04778
NAD+[m] + trans-4-hydroxy-L-proline[m] = 2 H+[m] + L-1-pyrroline-3-hydroxy-5-carboxylate[m] + NADH[m]
Left to rightBalancedEC 1.5.1.2Arginine and proline metabolismHuman-GEM MAR04779
NADP+[c] + trans-4-hydroxy-L-proline[c] = 2 H+[c] + L-1-pyrroline-3-hydroxy-5-carboxylate[c] + NADPH[c]
Left to rightBalancedEC 1.5.1.2Arginine and proline metabolismHuman-GEM MAR04780
NADP+[m] + trans-4-hydroxy-L-proline[m] = 2 H+[m] + L-1-pyrroline-3-hydroxy-5-carboxylate[m] + NADPH[m]
Left to rightBalancedEC 1.5.1.2Arginine and proline metabolismHuman-GEM MAR04781
4,8-dimethylnonanoylcarnitine[x] = 4,8-dimethylnonanoylcarnitine[c]
ReversibleBalancedTransportTransport reactionsHuman-GEM MAR04782
decanoic acid[c] = decanoic acid[r]
ReversibleBalancedTransportFatty acid oxidationHuman-GEM MAR04783
2 H2O[m] + L-1-pyrroline-3-hydroxy-5-carboxylate[m] + NAD+[m] = H+[m] + L-erythro-4-hydroxyglutamate[m] + NADH[m]
Left to rightBalancedEC 1.2.1.88Arginine and proline metabolismHuman-GEM MAR04784
2 H2O[m] + L-1-pyrroline-3-hydroxy-5-carboxylate[m] + NADP+[m] = H+[m] + L-erythro-4-hydroxyglutamate[m] + NADPH[m]
Left to rightBalancedEC 1.2.1.88Arginine and proline metabolismHuman-GEM MAR04785
AKG[m] + L-erythro-4-hydroxyglutamate[m] = 4-hydroxy-2-oxoglutarate[m] + glutamate[m]
Left to rightBalancedEC 2.6.1.1, 2.6.1.23Arginine and proline metabolismHuman-GEM MAR04786