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3,651–3,700 of 12,877 reactions from Human-GEM
cholesterol-ester-gamma-lin[r] + H2O[r] = cholesterol[r] + gamma-linolenate[r] + H+[r]
Left to rightBalancedEC 3.1.1.13Formation and hydrolysis of cholesterol estersHuman-GEM MAR03733
cholesterol-ester-dihomo-gamma[r] + H2O[r] = cholesterol[r] + dihomo-gamma-linolenate[r] + H+[r]
Left to rightBalancedEC 3.1.1.13Formation and hydrolysis of cholesterol estersHuman-GEM MAR03734
cholesterol-ester-arach[r] + H2O[r] = arachidonate[r] + cholesterol[r] + H+[r]
Left to rightBalancedEC 3.1.1.13Formation and hydrolysis of cholesterol estersHuman-GEM MAR03735
cholesterol-ester-7,10,13,16-docosa[r] + H2O[r] = adrenic acid[r] + cholesterol[r] + H+[r]
Left to rightBalancedEC 3.1.1.13Formation and hydrolysis of cholesterol esters
cholesterol-ester-9,12,15,18-tetraco[r] + H2O[r] = (9Z,12Z,15Z,18Z)-TTA[r] + cholesterol[r] + H+[r]
Left to rightBalancedEC 3.1.1.13Formation and hydrolysis of cholesterol estersHuman-GEM MAR03737
cholesterol-ester-6,9,12,15,18-tetraco[r] + H2O[r] = (6Z,9Z,12Z,15Z,18Z)-TPA[r] + cholesterol[r] + H+[r]
Left to rightBalancedEC 3.1.1.13Formation and hydrolysis of cholesterol estersHuman-GEM MAR03738
cholesterol-ester-4,7,10,13,16-docosa[r] + H2O[r] = (4Z,7Z,10Z,13Z,16Z)-DPA[r] + cholesterol[r] + H+[r]
Left to rightBalancedEC 3.1.1.13Formation and hydrolysis of cholesterol estersHuman-GEM MAR03739
cholesterol-ester-11,14-eicosa[r] + H2O[r] = (11Z,14Z)-eicosadienoic acid[r] + cholesterol[r] + H+[r]
Left to rightBalancedEC 3.1.1.13Formation and hydrolysis of cholesterol estersHuman-GEM MAR03740
cholesterol-ester-13,16-docosa[r] + H2O[r] = (13Z,16Z)-docosadienoic acid[r] + cholesterol[r] + H+[r]
Left to rightBalancedEC 3.1.1.13Formation and hydrolysis of cholesterol estersHuman-GEM MAR03741
cholesterol-ester-10,13,16-docosa[r] + H2O[r] = 10,13,16-docosatriynoic acid[r] + cholesterol[r] + H+[r]
Left to rightBalancedEC 3.1.1.13Formation and hydrolysis of cholesterol estersHuman-GEM MAR03742
CoA[m] + H+[m] + N-arachidonoylglycine[m] = arachidonyl-CoA[m] + glycine[m]
ReversibleBalancedEC 2.3.1.13Phenylalanine, tyrosine and tryptophan biosynthesisHuman-GEM MAR03743
AKG[m] + valine[m] = 3-methyl-2-oxobutyrate[m] + glutamate[m]
Left to rightBalancedEC 2.6.1.42Valine, leucine, and isoleucine metabolismHuman-GEM MAR03744
H+[c] + NADPH[c] + trans,cis-2,9-octadecadienoyl-CoA[c] = NADP+[c] + oleoyl-CoA[c]
ReversibleBalancedEC 5.1.99.4Fatty acid biosynthesisHuman-GEM MAR03745
3-methyl-2-oxobutyrate[c] = 3-methyl-2-oxobutyrate[m]
ReversibleBalancedTransportTransport reactionsHuman-GEM MAR03746
AKG[c] + valine[c] = 3-methyl-2-oxobutyrate[c] + glutamate[c]
Left to rightBalancedEC 2.6.1.42Valine, leucine, and isoleucine metabolismHuman-GEM MAR03747
H+[r] + NADPH[r] + trans,cis-2,9-octadecadienoyl-CoA[r] = NADP+[r] + oleoyl-CoA[r]
ReversibleBalancedEC 2.3.1.199Fatty acid biosynthesisHuman-GEM MAR03749
CoA[m] + H+[m] + isobutyrylglycine[m] = glycine[m] + isobutyryl-CoA[m]
ReversibleBalancedEC 2.3.1.13Glycine, serine and threonine metabolismHuman-GEM MAR03750
FADH2[m] + methacrylyl-CoA[m] = FAD[m] + isobutyryl-CoA[m]
ReversibleBalancedEC 1.3.8.5, 1.3.8.1Glycine, serine and threonine metabolismHuman-GEM MAR03752
H2O[m] + methacrylyl-CoA[m] = 3-hydroxyisobutyryl-CoA[m]
Left to rightBalancedEC 4.2.1.17Valine, leucine, and isoleucine metabolismHuman-GEM MAR03753
3-hydroxyisobutyryl-CoA[m] + H2O[m] = 3-hydroxyisobutyrate[m] + CoA[m] + H+[m]
Left to rightBalancedEC 3.1.2.4Valine, leucine, and isoleucine metabolismHuman-GEM MAR03755
3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA[x] + H2O[x] = 24(R),25(R)-varanoyl-CoA[x]
ReversibleBalancedEC 4.2.1.17Fatty acid oxidationHuman-GEM MAR03756
3-hydroxyisobutyrate[m] + NAD+[m] = 2-methyl-3-oxopropanoate[m] + H+[m] + NADH[m]
Left to rightBalancedEC 1.1.1.31, 1.1.1.35Valine, leucine, and isoleucine metabolismHuman-GEM MAR03757
NAD+[c] + 24(R),25(R)-varanoyl-CoA[c] = H+[c] + NADH[c] + 24-oxo-25(R)-trihydroxycoprostanoyl-CoA[c]
ReversibleBalancedEC 1.1.1.35Fatty acid oxidationHuman-GEM MAR03758
2-methyl-3-oxopropanoate[m] + H2O[m] + NAD+[m] = 2 H+[m] + methylmalonate[m] + NADH[m]
Left to rightBalancedEC 1.2.1.3, 1.2.3.1Valine, leucine, and isoleucine metabolismHuman-GEM MAR03759
2-methyl-3-oxopropanoate[m] + CoA[m] + NAD+[m] = (R)-methylmalonyl-CoA[m] + H+[m] + NADH[m]
Left to rightBalancedEC 1.2.1.18Valine, leucine, and isoleucine metabolismHuman-GEM MAR03761
2-methyl-3-oxopropanoate[c] = 2-methyl-3-oxopropanoate[m]
ReversibleBalancedTransportTransport reactionsHuman-GEM MAR03762
CoA[m] + H+[m] + methylmalonate[m] = (R)-methylmalonyl-CoA[m] + H2O[m]
Left to rightBalancedEC 3.1.2.17, 1.2.1.18Valine, leucine, and isoleucine metabolismHuman-GEM MAR03763
NAD+[x] + 24(R),25(R)-varanoyl-CoA[x] = 3alpha,7alpha,12alpha-trihydroxy-5beta-24-oxocholestanoyl-CoA[x] + H+[x] + NADH[x]
ReversibleBalancedEC 1.1.1.35Fatty acid oxidationHuman-GEM MAR03764
AKG[m] + leucine[m] = 4-methyl-2-oxopentanoate[m] + glutamate[m]
Left to rightBalancedEC 2.6.1.42, 2.6.1.6Valine, leucine, and isoleucine metabolismHuman-GEM MAR03765
5beta-cholestane-3alpha,7alpha,12alpha,26-tetrol[c] + H+[c] + NADPH[c] + O2[c] = 5beta-cholestane-3alpha,7alpha,12alpha,27,27-pentaol[c] + H2O[c] + NADP+[c]
Left to rightBalancedBile acid biosynthesisHuman-GEM MAR03766
5beta-cholestane-3alpha,7alpha,12alpha,26-tetrol[m] + H+[m] + NADPH[m] + O2[m] = 5beta-cholestane-3alpha,7alpha,12alpha,27,27-pentaol[m] + H2O[m] + NADP+[m]
Left to rightBalancedEC 1.14.15.15Bile acid biosynthesisHuman-GEM MAR03768
3-methylcrotonyl-CoA[m] + FADH2[m] = FAD[m] + isovaleryl-CoA[m]
ReversibleBalancedEC 1.3.8.4, 1.3.8.5Glycine, serine and threonine metabolismHuman-GEM MAR03770
CoA[m] + H+[m] + isovalerylglycine[m] = glycine[m] + isovaleryl-CoA[m]
ReversibleBalancedEC 2.3.1.13Glycine, serine and threonine metabolismHuman-GEM MAR03771
3-methylcrotonoylglycine[m] + CoA[m] + H+[m] = 3-methylcrotonyl-CoA[m] + glycine[m]
ReversibleBalancedEC 2.3.1.13Glycine, serine and threonine metabolismHuman-GEM MAR03772
3-methylcrotonyl-CoA[m] + ATP[m] + HCO3-[m] = 3-methylglutaconyl-CoA[m] + ADP[m] + H+[m] + Pi[m]
Left to rightBalancedEC 6.4.1.4Valine, leucine, and isoleucine metabolismHuman-GEM MAR03773
5beta-cholestane-3alpha,7alpha,12alpha,27,27-pentaol[c] = 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-27-al[c] + H2O[c]
ReversibleBalancedBile acid biosynthesisHuman-GEM MAR03774
3-methylglutaconyl-CoA[m] + H2O[m] = HMG-CoA[m]
ReversibleBalancedEC 4.2.1.18Valine, leucine, and isoleucine metabolismHuman-GEM MAR03775
H2O[r] + phosphatidylinositol-3,4,5-trisphosphate[r] = phosphatidylinositol-3,5-bisphosphate[r] + Pi[r]
ReversibleBalance undeterminableEC 3.1.3.67Phosphatidylinositol phosphate metabolismHuman-GEM MAR03776
AKG[c] + isoleucine[c] = 2-oxo-3-methylvalerate[c] + glutamate[c]
Left to rightBalancedEC 2.6.1.42Valine, leucine, and isoleucine metabolismHuman-GEM MAR03777
AKG[m] + isoleucine[m] = 2-oxo-3-methylvalerate[m] + glutamate[m]
Left to rightBalancedEC 2.6.1.42Valine, leucine, and isoleucine metabolismHuman-GEM MAR03778
H2O[c] + PI pool[c] = H+[c] + inositol[c] + phosphatidate-LD-PI pool[c]
Left to rightBalance undeterminableEC 3.1.4.4Phosphatidylinositol phosphate metabolismHuman-GEM MAR03779
H2O[g] + PI pool[g] = H+[g] + inositol[g] + phosphatidate-LD-PI pool[g]
Left to rightBalance undeterminableEC 3.1.4.4Phosphatidylinositol phosphate metabolismHuman-GEM MAR03781
2-methylbutyryl-CoA[m] + glycine[m] = 2-methylbutyrylglycine[m] + CoA[m] + H+[m]
ReversibleBalancedEC 2.3.1.13Glycine, serine and threonine metabolismHuman-GEM MAR03782
2-methylbutyryl-CoA[m] + FAD[m] = FADH2[m] + tiglyl-CoA[m]
ReversibleBalancedEC 1.3.8.5, 1.3.8.1Glycine, serine and threonine metabolismHuman-GEM MAR03784
H2O[m] + tiglyl-CoA[m] = (S)-3-hydroxy-2-methylbutyryl-CoA[m]
Left to rightBalancedEC 4.2.1.17Valine, leucine, and isoleucine metabolismHuman-GEM MAR03785
H2O[r] + PI pool[r] = H+[r] + inositol[r] + phosphatidate-LD-PI pool[r]
Left to rightBalance undeterminableEC 3.1.4.4Phosphatidylinositol phosphate metabolismHuman-GEM MAR03786
acetoacetate[m] + succinyl-CoA[m] = acetoacetyl-CoA[m] + succinate[m]
Left to rightBalancedEC 2.8.3.5Tricarboxylic acid cycle and glyoxylate/dicarboxylate metabolismHuman-GEM MAR03787
arachidonate[r] + FADH2[r] + O2[r] = 11,12-EET[r] + FAD[r] + H2O[r]
Left to rightBalancedEC 1.14.14.1Arachidonic acid metabolismHuman-GEM MAR03788
methylmalonate[c] = methylmalonate[m]
ReversibleBalancedTransportTransport reactionsHuman-GEM MAR03789
2-methyl-3-oxopropanoate[c] + H2O[c] + O2[c] = H+[c] + H2O2[c] + methylmalonate[c]
Left to rightBalancedEC 1.2.3.1Valine, leucine, and isoleucine metabolismHuman-GEM MAR03790