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CompoundsSubstances with curated findings
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ProteinsTransporters and enzymes
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ReactionsRhea and Human-GEM, by subsystem
ReachWhat a compound can become

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PathwaysReactions grouped under one name
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AnatomyTissues, by what is expressed there
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MaterialsSubstances that are not one molecule
AssessmentsRegulatory determinations, transcribed
DiseasesFeatures, genes, and where each sits

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Reference

Evidence

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Computational infrastructure for human biology, built on a provenance-aware knowledge graph. Findings retain their sources; research and simulation are the next layers.

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A reference for what the literature reports. Not medical advice.

© 2026 CatalystPrivacy TermsReference data under the licences listed on the attribution page.

Index

Reactions

Reactions from Rhea and Human-GEM · Reach

reactions in the graph: 31,435

By source

Rhea18,558
Human-GEM12,877

Inferred

Reference data, not a finding. Evidence key

Filter reactions by equationSource

Reactions

29,901–29,950 of 31,435, by identifier

(S)-azetidine-2-carboxylate + H2O = 2-hydroxy-4-aminobutanoate
Direction not assertedBalancedRhea 80499
S-adenosyl-L-methionine = (S)-azetidine-2-carboxylate + S-methyl-5'-thioadenosine + H(+)
Direction not assertedBalancedRhea 80503
(S)-azetidine-2-carboxylate + acetyl-CoA = (2S)-N-acetylazetidine-2-carboxylate + CoA + H(+)
Direction not assertedBalancedRhea 80507
2,4,6-trinitrotoluene + NADH = 2,4,6-trinitrotoluene radical + e(-) + NAD(+)
Direction not assertedBalance undeterminableRhea 80511
2,4,6-trinitrotoluene radical + O2 = 2,4,6-trinitrotoluene + superoxide + H(+)
Direction not assertedBalancedRhea 80515
2,4,6-trinitrotoluene + glutathione = S-(4,6-dinitrotoluyl)glutathione + nitrite + H(+)
Direction not assertedBalancedRhea 80519
2,4,6-trinitrotoluene + glutathione + AH2 = S-(2,6-dinitro-4-hydroxylaminotoluyl)glutathione + A + H2O

Direction not assertedBalancedRhea 80523

2 L-tryptophan = cyclo(L-Trp-L-Trp) + 2 H2O

Direction not assertedBalancedRhea 80527

2,4,6-trinitrotoluene + glutathione + AH2 = S-(2,4-dinitro-6-hydroxylaminotoluyl)glutathione + A + H2O

Direction not assertedBalancedRhea 80531

1'-[1,2-diacyl-sn-glycero-3-phospho]-3'-[2-acyl-sn-glycero-3-phospho]-glycerol + a 1,2-diacyl-sn-glycero-3-phosphocholine = a cardiolipin + a 1-acyl-sn-glycero-3-phosphocholine

Direction not assertedBalance undeterminableRhea 80535

1,3,5-trihydroxybenzene + S-adenosyl-L-methionine = 3,5-dihydroxyanisole + S-adenosyl-L-homocysteine + H(+)

Direction not assertedBalancedRhea 80539

3,5-dihydroxyanisole + S-adenosyl-L-methionine = 3,5-dimethoxyphenol + S-adenosyl-L-homocysteine + H(+)

Direction not assertedBalancedRhea 80543

3,5-dimethoxyphenol + S-adenosyl-L-methionine = 1,3,5-trimethoxybenzene + S-adenosyl-L-homocysteine + H(+)

Direction not assertedBalancedRhea 80547

eugenol + S-adenosyl-L-methionine = O-methyleugenol + S-adenosyl-L-homocysteine + H(+)

Direction not assertedBalancedRhea 80551

7'-O-demethylcephaeline + S-adenosyl-L-methionine = cephaeline + S-adenosyl-L-homocysteine + H(+)

Direction not assertedBalancedRhea 80555

2-methoxy-4-vinylphenol + O2 = vanillin + formaldehyde

Direction not assertedBalancedRhea 80559

orcinol + S-adenosyl-L-methionine = 3-methoxy-5-methylphenol + S-adenosyl-L-homocysteine + H(+)

Direction not assertedBalancedRhea 80563

3-methoxy-5-methylphenol + S-adenosyl-L-methionine = 3,5-dimethoxytoluene + S-adenosyl-L-homocysteine + H(+)

Direction not assertedBalancedRhea 80567

4-vinylphenol + O2 = 4-hydroxybenzaldehyde + formaldehyde

Direction not assertedBalancedRhea 80571

2,4-dihydroxybenzoate + H(+) = resorcinol + CO2

Direction not assertedBalancedRhea 80575

2-hydroxy-4-methoxybenzoate + H(+) = 3-methoxyphenol + CO2

Direction not assertedBalancedRhea 80579

chavicol + S-adenosyl-L-methionine = O-methylchavicol + S-adenosyl-L-homocysteine + H(+)

Direction not assertedBalancedRhea 80583

guaiacol + S-adenosyl-L-methionine = veratrole + S-adenosyl-L-homocysteine + H(+)

Direction not assertedBalancedRhea 80587

leukotriene A4 + H2O = (5S,6R)-dihydroxy-(7E,9E,11Z,14Z)-eicosatetraenoate

Direction not assertedBalancedRhea 80591

3-nitrophenol + 2 NADPH + 2 H(+) = 3-hydroxyaminophenol + 2 NADP(+) + H2O

Direction not assertedBalancedRhea 80595

(4-chloro-2-methylphenoxy)acetate + 2-oxoglutarate + O2 = 2-methyl-4-chlorophenol + glyoxylate + succinate + CO2

Direction not assertedBalancedRhea 80599

selenite + 2 Fe(III)-[cytochrome c] + H2O = 2 Fe(II)-[cytochrome] + selenate + 2 H(+)

Direction not assertedBalance undeterminableRhea 80603

(2-methylphenoxy)acetate + 2-oxoglutarate + O2 = 2-hydroxytoluene + glyoxylate + succinate + CO2

Direction not assertedBalancedRhea 80607

2,4-dichlorophenol + NADH + O2 + H(+) = 3,5-dichlorocatechol + NAD(+) + H2O

Direction not assertedBalancedRhea 80611

2-methyl-4-chlorophenol + NADH + O2 + H(+) = 5-chloro-3-methylcatechol + NAD(+) + H2O

Direction not assertedBalancedRhea 80615

4-chlorophenol + NADH + O2 + H(+) = 4-chlorocatechol + NAD(+) + H2O

Direction not assertedBalancedRhea 80619

2-chlorophenol + NADH + O2 + H(+) = 3-chlorocatechol + NAD(+) + H2O

Direction not assertedBalancedRhea 80623

5-chloro-3-methylcatechol + O2 = (2Z,4E)-4-chloro-2-methylmuconate + 2 H(+)

Direction not assertedBalancedRhea 80627

3-methylcatechol + O2 = (2Z,4Z)-2-methylmuconate + 2 H(+)

Direction not assertedBalancedRhea 80631

2 oxidized [4Fe-4S]-[ferredoxin] + taurine + H2O = aminoacetaldehyde + 2 reduced [4Fe-4S]-[ferredoxin] + sulfite + 3 H(+)

Direction not assertedBalance undeterminableRhea 80635

aminoacetaldehyde + 2 oxidized [4Fe-4S]-[ferredoxin] + H2O = 2 reduced [4Fe-4S]-[ferredoxin] + glycine + 3 H(+)

Direction not assertedBalance undeterminableRhea 80639

an aliphatic sulfonate + 4 oxidized [4Fe-4S]-[ferredoxin] + 2 H2O = 4 reduced [4Fe-4S]-[ferredoxin] + a carboxylate + sulfite + 6 H(+)

Direction not assertedBalance undeterminableRhea 80643

an aliphatic sulfonate + 2 oxidized [4Fe-4S]-[ferredoxin] + H2O = 2 reduced [4Fe-4S]-[ferredoxin] + an aldehyde + sulfite + 3 H(+)

Direction not assertedBalance undeterminableRhea 80647

2 oxidized [4Fe-4S]-[ferredoxin] + an aldehyde + H2O = 2 reduced [4Fe-4S]-[ferredoxin] + a carboxylate + 3 H(+)

Direction not assertedBalance undeterminableRhea 80651

oripavine + S-adenosyl-L-methionine = thebaine + S-adenosyl-L-homocysteine + H(+)

Direction not assertedBalancedRhea 80655

cephaeline + S-adenosyl-L-methionine = emetine + S-adenosyl-L-homocysteine + H(+)

Direction not assertedBalancedRhea 80659

deacetylisoipecoside + S-adenosyl-L-methionine = 6-O-methyldeacetylisoipecoside + S-adenosyl-L-homocysteine + H(+)

Direction not assertedBalancedRhea 80663

7-O-methyldeacetylisoipecoside + S-adenosyl-L-methionine = 6,7-O,O-dimethyldeacetylisoipecoside + S-adenosyl-L-homocysteine + H(+)

Direction not assertedBalancedRhea 80667

4-methylmuconolactone = (2Z,4Z)-3-methylmuconate + H(+)

Direction not assertedBalancedRhea 80671

4-methylcatechol + O2 = (2Z,4Z)-3-methylmuconate + 2 H(+)

Direction not assertedBalancedRhea 80675

5-methylsalicylate + NADH + O2 + 2 H(+) = 4-methylcatechol + CO2 + NAD(+) + H2O

Direction not assertedBalancedRhea 80679

4-methylsalicylate + NADH + O2 + 2 H(+) = 4-methylcatechol + CO2 + NAD(+) + H2O

Direction not assertedBalancedRhea 80683

3-methylsalicylate + NADH + O2 + 2 H(+) = 3-methylcatechol + CO2 + NAD(+) + H2O

Direction not assertedBalancedRhea 80687

isococlaurine + S-adenosyl-L-methionine = 7-O-methylcoclaurine + S-adenosyl-L-homocysteine + H(+)

Direction not assertedBalancedRhea 80691

(S)-norprotosinomenine + S-adenosyl-L-methionine = (S)-6-O-methylnorprotosinomenine + S-adenosyl-L-homocysteine + H(+)

Direction not assertedBalancedRhea 80695

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