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Reference

Evidence

CompoundsSubstances with curated findings
OutcomesMeasured endpoints
ProteinsTransporters and enzymes
InteractionsPairs that share biology
PapersEvery paper a finding cites
ArticlesReadings of the evidence

Chemistry

ReactionsRhea and Human-GEM, by subsystem
ReachWhat a compound can become

Reference layer

PathwaysReactions grouped under one name
ProcessesWhat proteins are annotated as doing
AnatomyTissues, by what is expressed there
Cell typesCells, by what is expressed there
OrganismsSpecies a compound is prepared from
MaterialsSubstances that are not one molecule
AssessmentsRegulatory determinations, transcribed
DiseasesFeatures, genes, and where each sits

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Reference

Evidence

Compounds
Outcomes
Proteins
Interactions
Papers
Articles

Chemistry

Reactions
Reach

Reference layer

Pathways
Processes
Anatomy
Cell types
Organisms
Materials
Assessments
Diseases

Atlas Graph Twin Access

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Computational infrastructure for human biology, built on a provenance-aware knowledge graph. Findings retain their sources; research and simulation are the next layers.

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A reference for what the literature reports. Not medical advice.

© 2026 CatalystPrivacy TermsReference data under the licences listed on the attribution page.

Index

Reactions

Reactions from Rhea and Human-GEM · Reach

reactions in the graph: 31,435

By source

Rhea18,558
Human-GEM12,877

Inferred

Reference data, not a finding. Evidence key

Filter reactions by equationSource

Reactions

29,551–29,600 of 31,435, by identifier

cholate + L-histidine = L-histidocholate + H2O
Direction not assertedBalancedRhea 79099
taurocholate + L-histidine = L-histidocholate + taurine
Direction not assertedBalancedRhea 79103
glycocholate + L-histidine = L-histidocholate + glycine
Direction not assertedBalancedRhea 79107
cholate + L-arginine = L-arginocholate + H2O
Direction not assertedBalancedRhea 79111
taurocholate + L-arginine = L-arginocholate + taurine
Direction not assertedBalancedRhea 79115
glycocholate + L-arginine = L-arginocholate + glycine
Direction not assertedBalancedRhea 79119
cholate + L-phenylalanine = L-phenylalanocholate + H2O

? Direction not asserted

Balanced

Rhea 79123

taurocholate + L-phenylalanine = L-phenylalanocholate + taurine

Direction not assertedBalancedRhea 79127

cholate + L-alanine = L-alanocholate + H2O

Direction not assertedBalancedRhea 79131

taurocholate + L-alanine = L-alanocholate + taurine

Direction not assertedBalancedRhea 79135

cholate + L-serine = L-serocholate + H2O

Direction not assertedBalancedRhea 79139

taurocholate + L-serine = L-serocholate + taurine

Direction not assertedBalancedRhea 79143

cis-4-hydroxycyclohexane-1-carboxylate + NAD(+) = 4-oxocyclohexane-1-carboxylate + NADH + H(+)

Direction not assertedBalancedRhea 79147

4-oxocyclohexane-1-carboxylate + O2 = 4-oxocyclohex-2-ene-1-carboxylate + H2O2

Direction not assertedBalancedRhea 79151

(4Z,15Z)-bilirubin IXalpha C12-beta-D-glucuronoside(in) + ATP + H2O = (4Z,15Z)-bilirubin IXalpha C12-beta-D-glucuronoside(out) + ADP + phosphate + H(+)

Direction not assertedBalancedTransportRhea 79155

4-oxocyclohex-2-ene-1-carboxylate + NAD(+) = 4-oxocyclohexa-2,5-diene-1-carboxylate + NADH + H(+)

Direction not assertedBalancedRhea 79159

4-oxocyclohexa-2,5-diene-1-carboxylate = 4-hydroxybenzoate

Direction not assertedBalancedRhea 79163

4alpha,5beta-5,20-epoxytax-11-ene-4-ol + reduced [NADPH--hemoprotein reductase] + O2 = 4alpha,5beta-5,20-epoxytax-11-ene-4,9-diol + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Direction not assertedBalance undeterminableRhea 79167

phytol + hexadecanoyl-CoA = hexadecanoate phytyl ester + CoA

Direction not assertedBalancedRhea 79171

cyclohexane-1-carboxylate + succinyl-CoA = cyclohexane-1-carbonyl-CoA + succinate

Direction not assertedBalancedRhea 79175

cyclohexane-1-carboxylate + butanoyl-CoA = cyclohexane-1-carbonyl-CoA + butanoate

Direction not assertedBalancedRhea 79179

N-hydroxyputrescine + acetyl-CoA = N(1)-acetyl-N(1)-hydroxyputrescine + CoA

Direction not assertedBalancedRhea 79183

(2E,6Z,9Z,12Z,15Z,18Z,21Z)-tetracosaheptaenoyl-CoA + H2O = (3R)-hydroxy-(6Z,9Z,12Z,15Z,18Z,21Z)-tetracosahexaenoyl-CoA

Left to rightBalancedRhea 79187

(3R)-hydroxy-(6Z,9Z,12Z,15Z,18Z,21Z)-tetracosahexaenoyl-CoA + NAD(+) = 3-oxo-(6Z,9Z,12Z,15Z,18Z,21Z)-tetracosahexaenoyl-CoA + NADH + H(+)

Left to rightBalancedRhea 79191

a ganglioside GD1alpha + CMP-N-acetyl-beta-neuraminate = a ganglioside GT1a alpha + CMP + H(+)

Direction not assertedBalance undeterminableRhea 79195

a ganglioside GA1 + 3'-phosphoadenylyl sulfate = a ganglioside SM1a + adenosine 3',5'-bisphosphate + H(+)

Direction not assertedBalance undeterminableRhea 79199

a ganglioside GA1 + 3'-phosphoadenylyl sulfate = a ganglioside SM1b + adenosine 3',5'-bisphosphate + H(+)

Direction not assertedBalance undeterminableRhea 79203

a ganglioside SM1a + 3'-phosphoadenylyl sulfate = a ganglioside SB1a + adenosine 3',5'-bisphosphate + H(+)

Direction not assertedBalance undeterminableRhea 79207

a ganglioside SM1b + 3'-phosphoadenylyl sulfate = a ganglioside SB1a + adenosine 3',5'-bisphosphate + H(+)

Direction not assertedBalance undeterminableRhea 79211

a ganglioside Fuc-GM1 + UDP-alpha-D-galactose = a ganglioside Fuc(Gal)-GM1 + UDP + H(+)

Direction not assertedBalance undeterminableRhea 79215

S-methyl-thiohydantoin-5-propanoate + H2O = hydantoin-5-propanoate + methanethiol

Direction not assertedBalancedRhea 79219

GDP-alpha-D-lincosamide + ergothioneine = ergothioneyl-alpha-D-lincosamide + GDP + 2 H(+)

Direction not assertedBalancedRhea 79223

hapalindole G + dimethylallyl diphosphate = ambiguine A + diphosphate

Direction not assertedBalancedRhea 79227

hapalindole U + dimethylallyl diphosphate + H(+) = ambiguine H + diphosphate

Direction not assertedBalancedRhea 79231

3,4-dimethoxy-L-phenylalanine = 3,4-dimethoxy-(E)-cinnamate + NH4(+)

Direction not assertedBalancedRhea 79235

(4Z,15Z)-bilirubin IXalpha C8,C12-beta-D-bisglucuronoside + H2O = (4Z,15Z)-bilirubin IXalpha C12-beta-D-glucuronoside + D-glucuronate + H(+)

Direction not assertedBalancedRhea 79239

(4Z,15Z)-bilirubin IXalpha C8,C12-beta-D-bisglucuronoside + H2O = (4Z,15Z)-bilirubin IXalpha C8-beta-D-glucuronoside + D-glucuronate + H(+)

Direction not assertedBalancedRhea 79243

(4Z,15Z)-bilirubin IXalpha C8-beta-D-glucuronoside + H2O = (4Z,15Z)-bilirubin IXalpha + D-glucuronate + H(+)

Direction not assertedBalancedRhea 79247

(4Z,15Z)-bilirubin IXalpha C12-beta-D-glucuronoside + H2O = (4Z,15Z)-bilirubin IXalpha + D-glucuronate + H(+)

Direction not assertedBalancedRhea 79251

zearalenone + H2O = hydrolyzed zearalenone + H(+)

Direction not assertedBalancedRhea 79255

hydrolyzed zearalenone + H(+) = decarboxylated hydrolyzed zearalenone + CO2

Direction not assertedBalancedRhea 79259

4-methylumbelliferone sulfate + phenol = phenyl sulfate + 4-methylumbelliferone

Direction not assertedBalancedRhea 79263

2-naphthyl sulfate + phenol = phenyl sulfate + 2-naphthol

Direction not assertedBalancedRhea 79267

(13S)-hydroperoxy-(9Z,11E,15Z)-octadecatrienoate = etherolenate + H2O

Direction not assertedBalancedRhea 79271

(13S)-hydroperoxy-(9Z,11E)-octadecadienoate = etheroleate + H2O

Direction not assertedBalancedRhea 79275

2 N-(3-carboxypropanoyl)-N-hydroxyputrescine + 2 ATP = putrebactin + 2 AMP + 2 diphosphate + 2 H(+)

Direction not assertedBalancedRhea 79279

2 N-(3-carboxypropanoyl)-N-hydroxyputrescine + ATP = pre-putrebactin + AMP + diphosphate + H(+)

Direction not assertedBalancedRhea 79283

pre-putrebactin + ATP = putrebactin + AMP + diphosphate + H(+)

Direction not assertedBalancedRhea 79287

2 N-(3-carboxypropanoyl)-N-hydroxycadaverine + 2 ATP = bisucaberin + 2 AMP + 2 diphosphate + 2 H(+)

Direction not assertedBalancedRhea 79291

2 N-(3-carboxypropanoyl)-N-hydroxycadaverine + ATP = bisucaberin B + AMP + diphosphate + H(+)

Direction not assertedBalancedRhea 79295

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