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Evidence

CompoundsSubstances with curated findings
OutcomesMeasured endpoints
ProteinsTransporters and enzymes
InteractionsPairs that share biology
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ReactionsRhea and Human-GEM, by subsystem
ReachWhat a compound can become

Reference layer

PathwaysReactions grouped under one name
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AnatomyTissues, by what is expressed there
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MaterialsSubstances that are not one molecule
AssessmentsRegulatory determinations, transcribed
DiseasesFeatures, genes, and where each sits

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Reference

Evidence

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Computational infrastructure for human biology, built on a provenance-aware knowledge graph. Findings retain their sources; research and simulation are the next layers.

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A reference for what the literature reports. Not medical advice.

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Index

Reactions

Reactions from Rhea and Human-GEM · Reach

reactions in the graph: 31,435

By source

Rhea18,558
Human-GEM12,877

Inferred

Reference data, not a finding. Evidence key

Filter reactions by equationSource

Reactions

29,501–29,550 of 31,435, by identifier

a long-chain fatty acyl-CoA + acetyl-CoA = a long-chain 3-oxo-fatty acyl-CoA + CoA
Right to leftBalance undeterminableRhea 78899
a medium-chain fatty acyl-CoA + acetyl-CoA = a medium-chain 3-oxoacyl-CoA + CoA
Right to leftBalance undeterminableRhea 78903
a short-chain fatty acyl-CoA + acetyl-CoA = a short-chain 3-oxoacyl-CoA + CoA
Direction not assertedBalance undeterminableRhea 78907
a very-long-chain (3S)-hydroxyacyl-CoA = a very-long-chain (2E)-enoyl-CoA + H2O
Direction not assertedBalance undeterminableRhea 78911
a long-chain (3S)-3-hydroxy fatty acyl-CoA = a long-chain (2E)-enoyl-CoA + H2O
Direction not assertedBalance undeterminableRhea 78915
a medium-chain (3S)-3-hydroxyacyl-CoA + NAD(+) = a medium-chain 3-oxoacyl-CoA + NADH + H(+)
Direction not assertedBalance undeterminableRhea 78919

a short-chain (3S)-3-hydroxyacyl-CoA + NAD(+) = a short-chain 3-oxoacyl-CoA + NADH + H(+)

Direction not assertedBalance undeterminableRhea 78923

a very-long-chain (3S)-hydroxyacyl-CoA + NAD(+) = a very-long-chain 3-oxoacyl-CoA + NADH + H(+)

Direction not assertedBalance undeterminableRhea 78927

a long-chain (3R)-hydroxyacyl-CoA = a long-chain (2E)-enoyl-CoA + H2O

Right to leftBalance undeterminableRhea 78931

a long-chain (3R)-hydroxyacyl-CoA + NAD(+) = a long-chain 3-oxo-fatty acyl-CoA + NADH + H(+)

Left to rightBalance undeterminableRhea 78935

1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + H2O = 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycerol + phosphocholine + H(+)

Direction not assertedBalancedRhea 78939

[DsrC protein]-trisulfide + NAD(+) + 3 H2O = [DsrC protein]-dithiol + sulfite + NADH + 3 H(+)

Direction not assertedBalance undeterminableRhea 78943

1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + H2O = 1,2-di-(9Z-octadecenoyl)-sn-glycerol + phosphocholine + H(+)

Direction not assertedBalancedRhea 78947

a 1,2-diacyl-sn-glycero-3-phosphoethanolamine + H2O = phosphoethanolamine + a 1,2-diacyl-sn-glycerol + H(+)

Left to rightBalance undeterminableRhea 78951

1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + H2O = phosphoethanolamine + 1,2-di-(9Z-octadecenoyl)-sn-glycerol + H(+)

Direction not assertedBalancedRhea 78955

1,2-dihexadecanoyl-sn-glycero-3-phosphoethanolamine + H2O = 1,2-dihexadecanoyl-sn-glycerol + phosphoethanolamine + H(+)

Direction not assertedBalancedRhea 78959

a 1,2-diacyl-sn-glycero-3-phospho-L-serine + H2O = O-phospho-L-serine + a 1,2-diacyl-sn-glycerol + H(+)

Direction not assertedBalance undeterminableRhea 78963

a 1,2-diacyl-sn-glycero-3-phosphoglycerol + H2O = glycerol 1-phosphate + a 1,2-diacyl-sn-glycerol + H(+)

Direction not assertedBalance undeterminableRhea 78967

(2E)-3-methyl-5-phosphooxypent-2-enoate + H(+) = isopentenyl phosphate + CO2

Direction not assertedBalancedRhea 78971

(R)-5-phosphomevalonate = (2E)-3-methyl-5-phosphooxypent-2-enoate + H2O

Direction not assertedBalancedRhea 78975

(2E,6E,10E)-geranylgeranyl diphosphate = bonnadiene + diphosphate

Direction not assertedBalancedRhea 78979

(2E,6E,10E)-geranylgeranyl diphosphate = allokutznerene + diphosphate

Direction not assertedBalancedRhea 78983

(2E,6E,10E)-geranylgeranyl diphosphate = cattleyene + diphosphate

Direction not assertedBalancedRhea 78987

a 4-carboxy-3-alkylbut-(2E)-enoyl-[ACP] + H(+) = a 3-alkylbut-(2E)-enoyl-[ACP] + CO2

Direction not assertedBalance undeterminableRhea 78991

a 3-carboxymethyl-3-hydroxyacyl-[ACP] = a 4-carboxy-3-alkylbut-(2E)-enoyl-[ACP] + H2O

Direction not assertedBalance undeterminableRhea 78995

3-aminoavenalumate + nitrite + ATP = 3-diazoavenalumate + AMP + diphosphate + H2O

Direction not assertedBalancedRhea 78999

(E)-3-aminocoumarate + nitrite + ATP + H(+) = (E)-3-diazocoumarate + AMP + diphosphate + H2O

Direction not assertedBalancedRhea 79003

3-amino-4-hydroxybenzoate + nitrite + ATP + H(+) = 3-diazo-4-hydroxybenzoate + AMP + diphosphate + H2O

Direction not assertedBalancedRhea 79007

ent-copalyl diphosphate = ent-beyerene + diphosphate

Direction not assertedBalancedRhea 79011

an alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-alpha-D-GlcNAc-diphospho-di-trans,poly-cis-dolichol(in) = an alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-alpha-D-GlcNAc-diphospho-di-trans,poly-cis-dolichol(out)

Direction not assertedBalance undeterminableTransportRhea 79015

N(1)-methyladenosine(58) in tRNA + 2-oxoglutarate + O2 = adenosine(58) in tRNA + formaldehyde + succinate + CO2

Direction not assertedBalancedRhea 79019

a beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-alpha-D-GlcNAc-diphospho-di-trans,poly-cis-dolichol + GDP-alpha-D-mannose = an alpha-D-Man-(1->6)-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-alpha-D-GlcNAc-diphospho-di-trans,poly-cis-dolichol + GDP + H(+)

Left to rightBalance undeterminableRhea 79023

an alpha-D-Man-(1->6)-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-alpha-D-GlcNAc-diphospho-di-trans,poly-cis-dolichol + GDP-alpha-D-mannose = an alpha-D-Man-(1->3)-[alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-alpha-D-GlcNAc-diphospho-di-trans,poly-cis-dolichol + GDP + H(+)

Left to rightBalance undeterminableRhea 79027

adenylyl MoO3-molybdopterin cofactor = adenylyl MoO2(OH)-molybdopterin cofactor

Direction not assertedBalancedRhea 79031

adenylyl MoO2(OH)-molybdopterin cofactor + H2O = Mo-molybdopterin + AMP + 2 H(+)

Direction not assertedBalancedRhea 79035

S-methyl-(E)-thiourocanate + H2O = S-methyl-thiohydantoin-5-propanoate

Direction not assertedBalancedRhea 79039

ergothioneine (thione form) + H(+) = ergothioneine

Direction not assertedBalancedRhea 79043

cordycepin + H2O + H(+) = 3'-deoxyinosine + NH4(+)

Left to rightBalancedRhea 79047

(3S)-hydroxy-3-methylglutaryl-[ACP] = 4-carboxy-3-methylbut-(2E)-enoyl-[ACP] + H2O

Direction not assertedBalance undeterminableRhea 79051

urobilinogen + 4 A = (4Z,15Z)-bilirubin IXalpha + 4 AH2

Direction not assertedBalancedRhea 79055

4-carboxy-3-methylbut-(2E)-enoyl-[ACP] + H(+) = 3-methylbut-(2E)-enoyl-[ACP] + CO2

Direction not assertedBalance undeterminableRhea 79059

urobilinogen + 2 A = (4Z,15Z)-mesobilirubin IXalpha + 2 AH2

Direction not assertedBalancedRhea 79063

(4Z,15Z)-bilirubin IXalpha + UDP-alpha-D-glucuronate = (4Z,15Z)-bilirubin IXalpha C8-beta-D-glucuronoside + UDP

Left to rightBalancedRhea 79067

(4Z,15Z)-bilirubin IXalpha C8-beta-D-glucuronoside + UDP-alpha-D-glucuronate = (4Z,15Z)-bilirubin IXalpha C8,C12-beta-D-bisglucuronoside + UDP

Left to rightBalancedRhea 79071

(4Z,15Z)-bilirubin IXalpha C12-beta-D-glucuronoside + UDP-alpha-D-glucuronate = (4Z,15Z)-bilirubin IXalpha C8,C12-beta-D-bisglucuronoside + UDP

Left to rightBalancedRhea 79075

cyclohexane-1-carboxylate + 2 reduced [2Fe-2S]-[ferredoxin] + O2 + 2 H(+) = trans-4-hydroxycyclohexane-1-carboxylate + 2 oxidized [2Fe-2S]-[ferredoxin] + H2O

Direction not assertedBalance undeterminableRhea 79079

(3R)-3-methyl-D-ornithyl-N(6)-L-lysine + NAD(+) = L-pyrrolysine + NH4(+) + NADH + 2 H(+)

Direction not assertedBalancedRhea 79083

an L-alpha-amino acid + cholate = an N-choloyl-L-alpha-amino acid + H2O

Direction not assertedBalance undeterminableRhea 79087

an L-alpha-amino acid + taurocholate = an N-choloyl-L-alpha-amino acid + taurine

Direction not assertedBalance undeterminableRhea 79091

glycocholate + an L-alpha-amino acid = an N-choloyl-L-alpha-amino acid + glycine

Direction not assertedBalance undeterminableRhea 79095

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