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Evidence

CompoundsSubstances with curated findings
OutcomesMeasured endpoints
ProteinsTransporters and enzymes
InteractionsPairs that share biology
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ReactionsRhea and Human-GEM, by subsystem
ReachWhat a compound can become

Reference layer

PathwaysReactions grouped under one name
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AnatomyTissues, by what is expressed there
Cell typesCells, by what is expressed there
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MaterialsSubstances that are not one molecule
AssessmentsRegulatory determinations, transcribed
DiseasesFeatures, genes, and where each sits

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Reference

Evidence

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Interactions
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Reactions
Reach

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Cell types
Organisms
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Diseases

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Computational infrastructure for human biology, built on a provenance-aware knowledge graph. Findings retain their sources; research and simulation are the next layers.

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A reference for what the literature reports. Not medical advice.

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Index

Reactions

Reactions from Rhea and Human-GEM · Reach

reactions in the graph: 31,435

By source

Rhea18,558
Human-GEM12,877

Inferred

Reference data, not a finding. Evidence key

Filter reactions by equationSource

Reactions

29,451–29,500 of 31,435, by identifier

a 3-O-beta-D-glucosyl-beta-D-glucuronoside + phosphate = a beta-D-glucuronoside + alpha-D-glucose 1-phosphate
Direction not assertedBalance undeterminableRhea 78699
4-(hydroxy(methyl)phosphoryl)-2-oxobutanoate + L-glutamate = L-phosphinothricin + 2-oxoglutarate
Direction not assertedBalancedRhea 78703
an N-terminal L-arginyl-L-aminoacyl-[protein] + H2O = an N-terminal L-alpha-aminoacyl-[protein] + L-arginine
Direction not assertedBalance undeterminableRhea 78707
3-O-beta-D-glucosyl-D-glucuronate + phosphate = aldehydo-D-glucuronate + alpha-D-glucose 1-phosphate
Direction not assertedBalancedRhea 78711
3-dehydro-alpha-D-glucosyl beta-D-fructofuranoside + H2O = 3-dehydro-D-glucose + D-fructose
Direction not assertedBalancedRhea 78715
3-dehydro-alpha,alpha-trehalose + H2O = 3-dehydro-D-glucose + D-glucose
Direction not assertedBalancedRhea

78719

3'-dehydromaltose + H2O = 3-dehydro-D-glucose + D-glucose

Direction not assertedBalancedRhea 78723

(3S)-hydroxydocosanoyl-CoA + NAD(+) = 3-oxodocosanoyl-CoA + NADH + H(+)

Direction not assertedBalancedRhea 78727

(3S)-hydroxyeicosanoyl-CoA + NAD(+) = 3-oxoeicosanoyl-CoA + NADH + H(+)

Left to rightBalancedRhea 78731

(3S)-hydroxytetracosanoyl-CoA + NAD(+) = 3-oxotetracosanoyl-CoA + NADH + H(+)

Direction not assertedBalancedRhea 78735

(3S)-hydroxyoctadecanoyl-CoA + NAD(+) = 3-oxooctadecanoyl-CoA + NADH + H(+)

Left to rightBalancedRhea 78739

ipecoside + H2O = ipecoside aglycone + D-glucose

Direction not assertedBalancedRhea 78743

an alpha-L-rhamnosyl-(1->4)-beta-D-glucuronide = a 4-deoxy-alpha-L-threo-hex-4-enopyranuronoside + L-rhamnopyranose

Direction not assertedBalance undeterminableRhea 78747

a fatty acyl-CoA + (R)-carnitine = a fatty acyl-L-carnitine + CoA

Direction not assertedBalance undeterminableRhea 78751

alpha-L-rhamnosyl-(1->4)-D-glucuronate = 4-deoxy-L-threo-hex-4-enopyranuronate + L-rhamnopyranose

Direction not assertedBalancedRhea 78755

L-isoleucyl-[protein] + AH2 + 2 S-adenosyl-L-methionine = methylcyclopropylglycine-[protein] + 2 5'-deoxyadenosine + 2 L-methionine + A + 2 H(+)

Direction not assertedBalance undeterminableRhea 78759

deacetylipecoside + H2O = deacetylipecoside aglycone + D-glucose

Direction not assertedBalancedRhea 78763

3''-dehydroorientin = 1,5-anhydro-D-erythro-hex-1-en-3-ulose + luteolin

Direction not assertedBalancedRhea 78767

3''-dehydroisoorientin = 1,5-anhydro-D-erythro-hex-1-en-3-ulose + luteolin

Direction not assertedBalancedRhea 78771

3''-dehydroisovitexin = 1,5-anhydro-D-erythro-hex-1-en-3-ulose + apigenin

Direction not assertedBalancedRhea 78775

L-arginine + 2 H2O + 2 H(+) = L-ornithine + 2 NH4(+) + CO2

Direction not assertedBalancedRhea 78779

luteolin + UDP-alpha-D-glucose = isoorientin + UDP + H(+)

Direction not assertedBalancedRhea 78783

apigenin + UDP-alpha-D-glucose = isovitexin + UDP + H(+)

Direction not assertedBalancedRhea 78787

D-cysteine + O2 + H2O = 2-oxo-3-sulfanylpropanoate + H2O2 + NH4(+)

Left to rightBalancedRhea 78791

a 3-oxoacyl-[ACP] + acetyl-[ACP] + H2O = a 3-carboxymethyl-3-hydroxy-acyl-[ACP] + holo-[ACP] + H(+)

Direction not assertedBalance undeterminableRhea 78795

a D-alpha-amino acid + O2 = a 2-iminocarboxylate + H2O2

Direction not assertedBalance undeterminableRhea 78799

a 2-iminocarboxylate + H2O = a 2-oxocarboxylate + NH4(+)

Direction not assertedBalance undeterminableRhea 78803

N(1)-[(S)-3-amino-3-carboxypropyl]agmatine + H(+) = N(1)-(3-aminopropyl)agmatine + CO2

Direction not assertedBalancedRhea 78807

N(1)-[(S)-3-amino-3-carboxypropyl]agmatine + NADP(+) + H2O = L-aspartate 4-semialdehyde + agmatine + NADPH + H(+)

Direction not assertedBalancedRhea 78811

putrescine + NADPH + O2 = N-hydroxyputrescine + NADP(+) + H2O

Direction not assertedBalancedRhea 78815

L-arginine + 2-oxoglutarate = 5-guanidino-2-oxopentanoate + L-glutamate

Direction not assertedBalancedRhea 78819

(3R)-5-guanidino-3-methyl-2-oxopentanoate + L-aspartate = (3R)-3-methyl-L-arginine + oxaloacetate

Direction not assertedBalancedRhea 78823

(E)-4-coumarate + H2O = 4-hydroxybenzaldehyde + acetate

Direction not assertedBalancedRhea 78827

puerarin + 3-dehydro-D-glucose = 3''-dehydropuerarin + D-glucose

Direction not assertedBalancedRhea 78831

3''-dehydropuerarin = daidzein + 1,5-anhydro-D-erythro-hex-1-en-3-ulose

Direction not assertedBalancedRhea 78835

[DsrC protein]-dithiol + 2 a quinone + hydrogen sulfide + H(+) = [DsrC protein]-trisulfide + 2 a quinol

Direction not assertedBalance undeterminableRhea 78839

a fatty acid(in) + ATP + H2O = a fatty acid(out) + ADP + phosphate + H(+)

Direction not assertedBalance undeterminableTransportRhea 78843

a very-long-chain 2,3-saturated fatty acyl-CoA + O2 = a very-long-chain (2E)-enoyl-CoA + H2O2

Left to rightBalance undeterminableRhea 78847

a long-chain 2,3-saturated fatty acyl-CoA + O2 = a long-chain (2E)-enoyl-CoA + H2O2

Left to rightBalance undeterminableRhea 78851

a medium-chain 2,3-saturated fatty acyl-CoA + O2 = a medium-chain (2E)-enoyl-CoA + H2O2

Left to rightBalance undeterminableRhea 78855

a short-chain 2,3-saturated fatty acyl-CoA + O2 = a short-chain (2E)-enoyl-CoA + H2O2

Direction not assertedBalance undeterminableRhea 78859

a short-chain (3R)-hydroxy fatty acyl-CoA = a short-chain (2E)-enoyl-CoA + H2O

Direction not assertedBalance undeterminableRhea 78863

a medium-chain (3R)-hydroxyacyl-CoA = a medium-chain (2E)-enoyl-CoA + H2O

Right to leftBalance undeterminableRhea 78867

a very-long-chain (3R)-3-hydroxyacyl-CoA + NAD(+) = a very-long-chain 3-oxoacyl-CoA + NADH + H(+)

Left to rightBalance undeterminableRhea 78871

a medium-chain (3R)-hydroxyacyl-CoA + NAD(+) = a medium-chain 3-oxoacyl-CoA + NADH + H(+)

Left to rightBalance undeterminableRhea 78875

a short-chain (3R)-hydroxy fatty acyl-CoA + NAD(+) = a short-chain 3-oxoacyl-CoA + NADH + H(+)

Direction not assertedBalance undeterminableRhea 78879

6-O-methyldeacetylipecoside + H2O = 6-O-methyldeacetylipecoside aglycone + D-glucose

Direction not assertedBalancedRhea 78883

deacetylisoipecoside + H2O = deacetylisoipecoside aglycone + D-glucose

Direction not assertedBalancedRhea 78887

6-O-methyldeacetylisoipecoside + H2O = 6-O-methyldeacetylisoipecoside aglycone + D-glucose

Direction not assertedBalancedRhea 78891

a very long-chain fatty acyl-CoA + acetyl-CoA = a very-long-chain 3-oxoacyl-CoA + CoA

Right to leftBalance undeterminableRhea 78895

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