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CompoundsSubstances with curated findings
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ProteinsTransporters and enzymes
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ReactionsRhea and Human-GEM, by subsystem
ReachWhat a compound can become

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PathwaysReactions grouped under one name
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AnatomyTissues, by what is expressed there
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MaterialsSubstances that are not one molecule
AssessmentsRegulatory determinations, transcribed
DiseasesFeatures, genes, and where each sits

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Reference

Evidence

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Reach

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Computational infrastructure for human biology, built on a provenance-aware knowledge graph. Findings retain their sources; research and simulation are the next layers.

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A reference for what the literature reports. Not medical advice.

© 2026 CatalystPrivacy TermsReference data under the licences listed on the attribution page.

Index

Reactions

Reactions from Rhea and Human-GEM · Reach

reactions in the graph: 31,435

By source

Rhea18,558
Human-GEM12,877

Inferred

Reference data, not a finding. Evidence key

Filter reactions by equationSource

Reactions

29,401–29,450 of 31,435, by identifier

CMP-5'-(N-acetyl-N-hydroxy-3-aminopropyl)phosphonate + H2O = 3-(N-acetyl-N-hydroxy)aminopropylphosphonate + CMP + H(+)
Direction not assertedBalancedRhea 78499
3-(N-acetyl-N-hydroxy)aminopropylphosphonate + 2-oxoglutarate + O2 = (R)-(3-(acetylhydroxyamino)-2-hydroxypropyl)phosphonate + succinate + CO2
Direction not assertedBalancedRhea 78503
a 5'-end (N(2),N(7)-dimethyl 5'-triphosphoguanosine)-ribonucleoside in snoRNA + S-adenosyl-L-methionine = a 5'-end (N(2),N(2),N(7)-trimethyl 5'-triphosphoguanosine)-ribonucleoside in snoRNA + S-adenosyl-L-homocysteine + H(+)
Left to rightBalance undeterminableRhea 78507
a 5'-end (5'-triphosphoguanosine)-ribonucleoside in snRNA + S-adenosyl-L-methionine = a 5'-end (N(7)-methyl 5'-triphosphoguanosine)-ribonucleoside in snRNA + S-adenosyl-L-homocysteine
Direction not assertedBalance undeterminableRhea 78511
a 5'-end (5'-triphosphoguanosine)-ribonucleoside in snoRNA + S-adenosyl-L-methionine = a 5'-end (N(7)-methyl 5'-triphosphoguanosine)-ribonucleoside in snoRNA + S-adenosyl-L-homocysteine
Direction not assertedBalance undeterminableRhea 78515
N-acetyl-2,7-anhydro-alpha-neuraminate + H2O = N-acetyl-alpha-neuraminate

Direction not assertedBalancedRhea 78519

2-deoxy-2,3-dehydro-N-acetylneuraminate + H2O = N-acetyl-alpha-neuraminate

Direction not assertedBalancedRhea 78523

adenosine(N)/adenosine(N+1) in rRNA + 4 S-adenosyl-L-methionine = N(6)-dimethyladenosine(N)/N(6)-dimethyladenosine(N+1) in rRNA + 4 S-adenosyl-L-homocysteine + 4 H(+)

Direction not assertedUnbalancedRhea 78527

a beta-D-glucosylceramide + H2O = a beta-D-glucosyll-(1<->1')-sphingoid base + a fatty acid

Direction not assertedBalance undeterminableRhea 78531

N-acetyl-alpha-neuraminate(out) + 2 Na(+)(out) = N-acetyl-alpha-neuraminate(in) + 2 Na(+)(in)

Direction not assertedBalancedTransportRhea 78535

4 nitric oxide + O2 + 2 H2O = 4 nitrite + 4 H(+)

Left to rightBalancedRhea 78539

2 L-cysteine = S-sulfanyl-L-cysteine + L-alanine

Left to rightBalancedRhea 78543

Rb(+)(in) = Rb(+)(out)

Direction not assertedBalancedTransportRhea 78547

Li(+)(in) = Li(+)(out)

Direction not assertedBalancedTransportRhea 78551

Cs(+)(in) = Cs(+)(out)

Direction not assertedBalancedTransportRhea 78555

(3S)-hydroxytetracosanoyl-CoA = (2E)-tetracosenoyl-CoA + H2O

Direction not assertedBalancedRhea 78559

(3R)-hydroxytetracosanoyl-CoA + NAD(+) = 3-oxotetracosanoyl-CoA + NADH + H(+)

Direction not assertedBalancedRhea 78563

docosanoyl-CoA + acetyl-CoA = 3-oxotetracosanoyl-CoA + CoA

Direction not assertedBalancedRhea 78567

docosanoyl-CoA + O2 = (2E)-docosenoyl-CoA + H2O2

Left to rightBalancedRhea 78571

(3S)-hydroxydocosanoyl-CoA = (2E)-docosenoyl-CoA + H2O

Direction not assertedBalancedRhea 78575

(3R)-hydroxydocosanoyl-CoA + NAD(+) = 3-oxodocosanoyl-CoA + NADH + H(+)

Direction not assertedBalancedRhea 78579

eicosanoyl-CoA + acetyl-CoA = 3-oxodocosanoyl-CoA + CoA

Direction not assertedBalancedRhea 78583

eicosanoyl-CoA + O2 = (2E)-eicosenoyl-CoA + H2O2

Left to rightBalancedRhea 78587

(3S)-hydroxyeicosanoyl-CoA = (2E)-eicosenoyl-CoA + H2O

Right to leftBalancedRhea 78591

(3R)-hydroxyeicosanoyl-CoA + NAD(+) = 3-oxoeicosanoyl-CoA + NADH + H(+)

Direction not assertedBalancedRhea 78595

octadecanoyl-CoA + acetyl-CoA = 3-oxoeicosanoyl-CoA + CoA

Right to leftBalancedRhea 78599

(3S)-hydroxyoctadecanoyl-CoA = (2E)-octadecenoyl-CoA + H2O

Right to leftBalancedRhea 78603

(3R)-hydroxyoctadecanoyl-CoA + NAD(+) = 3-oxooctadecanoyl-CoA + NADH + H(+)

Direction not assertedBalancedRhea 78607

15-hydroxy-(5Z,8Z,11Z,13E)-eicosatetraenoate + reduced [NADPH--hemoprotein reductase] + O2 = 15,20-dihydroxy-(5Z,8Z,11Z,13E)-eicosatetraenoate + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Direction not assertedBalance undeterminableRhea 78611

L-lysine + ATP + H(+) = L-lysyl-5'-AMP + diphosphate

Direction not assertedBalancedRhea 78615

L-lysyl-5'-AMP + tRNA(Lys) = L-lysyl-tRNA(Lys) + AMP + H(+)

Direction not assertedBalancedRhea 78619

L-lysyl-5'-AMP + ATP = P(1),P(4)-bis(5'-adenosyl) tetraphosphate + L-lysine

Direction not assertedBalancedRhea 78623

S-sulfanyl-L-cysteine + L-cysteine = S-disulfanyl-L-cysteine + L-alanine

Left to rightBalancedRhea 78627

hexacosanoyl-CoA + O2 = (2E)-hexacosenoyl-CoA + H2O2

Left to rightBalancedRhea 78631

3-oxohexacosanoyl-CoA + NADH + H(+) = (3R)-hydroxyhexacosanoyl-CoA + NAD(+)

Right to leftBalancedRhea 78635

tetracosanoyl-CoA + acetyl-CoA = 3-oxohexacosanoyl-CoA + CoA

Direction not assertedBalancedRhea 78639

(3R)-hydroxytetradecanoyl-CoA = (2E)-tetradecenoyl-CoA + H2O

Direction not assertedBalancedRhea 78643

S-sulfanyl-L-cysteine + tRNA(Cys) + ATP = (S)-sulfanyl-L-cysteinyl-tRNA(Cys) + AMP + diphosphate

Left to rightBalancedRhea 78647

S-disulfanyl-L-cysteine + tRNA(Cys) + ATP = (S)-disulfanyl-L-cysteinyl-tRNA(Cys) + AMP + diphosphate

Left to rightBalancedRhea 78651

(2E,6E)-farnesyl diphosphate = silphinene + diphosphate

Direction not assertedBalancedRhea 78655

silphinene-15-oate + 2 reduced [NADPH--hemoprotein reductase] + 2 O2 = gamma-lactone-2-keto[5.5.5.5]fenestrane + 2 oxidized [NADPH--hemoprotein reductase] + 3 H2O + H(+)

Direction not assertedBalance undeterminableRhea 78659

gamma-lactone-2-keto[5.5.5.5]fenestrane + NADPH + O2 + H(+) = penifulvin A + NADP(+) + H2O

Direction not assertedBalancedRhea 78663

(3R)-hydroxytetradecanoyl-CoA + NAD(+) = 3-oxotetradecanoyl-CoA + NADH + H(+)

Direction not assertedBalancedRhea 78667

(3R)-3-hydroxydodecanoyl-CoA + NAD(+) = 3-oxododecanoyl-CoA + NADH + H(+)

Direction not assertedBalancedRhea 78671

silphinene + 3 reduced [NADPH--hemoprotein reductase] + 3 O2 = silphinene-15-oate + 3 oxidized [NADPH--hemoprotein reductase] + 4 H2O + 4 H(+)

Direction not assertedBalance undeterminableRhea 78675

Sr(2+)(in) = Sr(2+)(out)

Direction not assertedBalancedTransportRhea 78679

a 5'-end triphospho-ribonucleoside in mRNA + H2O = a 5'-end phospho-ribonucleoside in mRNA + diphosphate + H(+)

Left to rightBalance undeterminableRhea 78683

adenylyl-molybdopterin + molybdate + H(+) = adenylyl MoO3-molybdopterin cofactor + H2O

Direction not assertedBalancedRhea 78687

a D-glucoside + [(1->2)-beta-D-glucosyl](n) = a beta-D-glucosyl-(1->2)-D-glucoside + [(1->2)-beta-D-glucosyl](n-1)

Direction not assertedBalance undeterminableRhea 78691

a ganglioside GA2 + UDP-alpha-D-galactose = a ganglioside GA1 + UDP + H(+)

Direction not assertedBalance undeterminableRhea 78695

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