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CompoundsSubstances with curated findings
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ReactionsRhea and Human-GEM, by subsystem
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Reference

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Computational infrastructure for human biology, built on a provenance-aware knowledge graph. Findings retain their sources; research and simulation are the next layers.

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A reference for what the literature reports. Not medical advice.

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Index

Reactions

Reactions from Rhea and Human-GEM · Reach

reactions in the graph: 31,435

By source

Rhea18,558
Human-GEM12,877

Inferred

Reference data, not a finding. Evidence key

Filter reactions by equationSource

Reactions

28,401–28,450 of 31,435, by identifier

(-)-cyclopeptine + 2-oxoglutarate + O2 = (Z)-dehydrocyclopeptine + succinate + CO2 + H2O
Direction not assertedBalancedRhea 74479
(Z)-dehydrocyclopeptine + 2-oxoglutarate + O2 = (-)-cyclopenine + succinate + CO2
Direction not assertedBalancedRhea 74483
O-methyl-L-tyrosine + anthranilate + S-adenosyl-L-methionine + 2 ATP = (-)-4'-methoxycyclopeptine + 2 AMP + S-adenosyl-L-homocysteine + 2 diphosphate + 2 H(+)
Direction not assertedBalancedRhea 74487
[(1'E)-5'-(3',3'-dimethyloxiran-2'-yl)-3'-hydroxy-3'-methylpent-1'-en-1'-yl]-quinolinone B = yaequinolone D
Direction not assertedBalancedRhea 74491
[(1'E)-5'-(3',3'-dimethyloxiran-2'-yl)-3'-hydroxy-3'-methylpent-1'-en-1'-yl]-quinolinone B = yaequinolone C
Direction not assertedBalancedRhea 74495
yaequinolone D + NADPH + H(+) = penigequinolone A + NADP(+) + H2O
Direction not assertedBalancedRhea

74499

yaequinolone D + NADPH + H(+) = penigequinolone B + NADP(+) + H2O

Direction not assertedBalancedRhea 74503

[(1'E)-5'-(3',3'-dimethyloxiran-2'-yl)-3'-hydroxy-3'-methylpent-1'-en-1'-yl]-quinolinone B = (1'E,3'E)-5-(3,3-dimethyloxiran-2-yl)-3-methylhexa-1,3-dienyl-quinolinone B + H2O

Direction not assertedBalancedRhea 74507

(1'E,3'E)-5-(3,3-dimethyloxiran-2-yl)-3-methylhexa-1,3-dienyl-quinolinone B = aspoquinolone A

Direction not assertedBalancedRhea 74511

(1'E,3'E)-5-(3,3-dimethyloxiran-2-yl)-3-methylhexa-1,3-dienyl-quinolinone B = aspoquinolone B

Direction not assertedBalancedRhea 74515

1-(3-O-sulfo-beta-D-galactosyl)-ceramide + H2O = a beta-D-Gal-(1<->1')-ceramide + sulfate + H(+)

Direction not assertedBalance undeterminableRhea 74519

L-lysine + 2 S-adenosyl-L-methionine = N(6),N(6)-dimethyl-L-lysine + 2 S-adenosyl-L-homocysteine + 2 H(+)

Direction not assertedBalancedRhea 74523

N(6),N(6)-dimethyl-L-lysine + H(+) = N,N-dimethyl-cadaverine + CO2

Direction not assertedBalancedRhea 74527

archaetidylglycerol + AH2 + 2 S-adenosyl-L-methionine = macrocyclic archaetidylglycerol + 2 5'-deoxyadenosine + 2 L-methionine + A + 2 H(+)

Direction not assertedBalancedRhea 74531

2 archaetidylglycerol + 2 AH2 + 4 S-adenosyl-L-methionine = glycerol dibiphytanyl glycerol tetraether glycerophospholipid + 4 5'-deoxyadenosine + 4 L-methionine + 2 A + 4 H(+)

Direction not assertedBalancedRhea 74535

creatinine(in) = creatinine(out)

Direction not assertedBalancedTransportRhea 74539

(2E,6E,10E)-geranylgeranyl diphosphate = (E,E,E)-alpha-springene + diphosphate

Direction not assertedBalancedRhea 74543

(2E,6E,10E)-geranylgeranyl diphosphate = talarodiene + diphosphate

Direction not assertedBalancedRhea 74547

L-seryl-tRNA(Ser) + H2O = tRNA(Ser) + L-serine

Direction not assertedBalancedRhea 74551

(S)-malate(out) = (S)-malate(in)

Direction not assertedBalancedTransportRhea 74555

aldosterone = aldosterone hemiacetal

Direction not assertedBalancedRhea 74559

aldosterone hemiacetal + UDP-alpha-D-glucuronate = aldosterone hemiacetal 18-beta-glucuronide + UDP + H(+)

Direction not assertedBalancedRhea 74563

N-acetyl-L-cysteine(out) + L-glutamate(in) = N-acetyl-L-cysteine(in) + L-glutamate(out)

Direction not assertedBalancedTransportRhea 74567

N-terminal N(alpha)-acetyl-L-methionyl-L-aspartyl-[protein] + H2O = N-terminal L-aspartyl-[protein] + N-acetyl-L-methionine

Left to rightBalance undeterminableRhea 74571

N-terminal N(alpha)-acetyl-L-methionyl-L-glutamyl-[protein] + H2O = N-terminal L-glutamyl-[protein] + N-acetyl-L-methionine

Left to rightBalance undeterminableRhea 74575

N-terminal N(alpha)-acetyl-L-cysteinyl-L-aspartyl-[protein] + H2O = N-terminal L-aspartyl-[protein] + N-acetyl-L-cysteine

Left to rightBalance undeterminableRhea 74579

N-terminal N(alpha)-acetyl-L-cysteinyl-L-glutamyl-[protein] + H2O = N-terminal L-glutamyl-[protein] + N-acetyl-L-cysteine

Left to rightBalance undeterminableRhea 74583

(2E,6E)-farnesyl diphosphate = (+)-exo-beta-bergamotene + diphosphate

Direction not assertedBalancedRhea 74587

(+)-exo-beta-bergamotene + 2 reduced [NADPH--hemoprotein reductase] + 3 O2 = 5-dehydro-6-demethoxyfumagillol + 2 oxidized [NADPH--hemoprotein reductase] + 3 H2O + 2 H(+)

Direction not assertedBalance undeterminableRhea 74591

(2S,3R)-3-methyl-L-aspartate = mesaconate + NH4(+)

Direction not assertedBalancedRhea 74595

UDP-alpha-D-galactose(in) + AMP(out) = UDP-alpha-D-galactose(out) + AMP(in)

Direction not assertedBalancedTransportRhea 74599

UDP-alpha-D-galactose(in) + CMP(out) = UDP-alpha-D-galactose(out) + CMP(in)

Direction not assertedBalancedTransportRhea 74603

UDP-N-acetyl-alpha-D-galactosamine(out) + UDP-alpha-D-galactose(in) = UDP-N-acetyl-alpha-D-galactosamine(in) + UDP-alpha-D-galactose(out)

Direction not assertedBalancedTransportRhea 74607

UDP-N-acetyl-alpha-D-glucosamine(out) + UDP-alpha-D-galactose(in) = UDP-N-acetyl-alpha-D-glucosamine(in) + UDP-alpha-D-galactose(out)

Direction not assertedBalancedTransportRhea 74611

UDP-alpha-D-galactose(in) + UDP-alpha-D-glucose(out) = UDP-alpha-D-galactose(out) + UDP-alpha-D-glucose(in)

Direction not assertedBalancedTransportRhea 74615

UMP(out) + CMP(in) = UMP(in) + CMP(out)

Direction not assertedBalancedTransportRhea 74619

UMP(out) + AMP(in) = UMP(in) + AMP(out)

Direction not assertedBalancedTransportRhea 74623

prefumagillin + NADPH + 2 O2 = fumagillin + acetaldehyde + NADP(+) + H2O

Direction not assertedBalancedRhea 74627

O-acetyl-L-homoserine + 3-methyl-2-oxobutanoate = (6S)-6-amino-3,3-dimethyl-2-oxoheptanedioate + acetate + H(+)

Direction not assertedBalancedRhea 74631

5-dehydro-6-demethoxyfumagillol + 2-oxoglutarate + O2 = 5-dehydro-6-demethoxy-6-hydroxyfumagillol + succinate + CO2

Direction not assertedBalancedRhea 74635

CMP-N-acetyl-beta-neuraminate(in) + AMP(out) = CMP-N-acetyl-beta-neuraminate(out) + AMP(in)

Direction not assertedBalancedTransportRhea 74639

UMP(out) + CMP-N-acetyl-beta-neuraminate(in) = UMP(in) + CMP-N-acetyl-beta-neuraminate(out)

Direction not assertedBalancedTransportRhea 74643

N-acetyl-D-glucosamine + GTP = N-acetyl-D-glucosamine 6-phosphate + GDP + H(+)

Direction not assertedBalancedRhea 74647

N-acetyl-D-glucosamine + CTP = N-acetyl-D-glucosamine 6-phosphate + CDP + H(+)

Direction not assertedBalancedRhea 74651

ITP + N-acetyl-D-glucosamine = IDP + N-acetyl-D-glucosamine 6-phosphate + H(+)

Direction not assertedBalancedRhea 74655

N-acetyl-D-glucosamine + UTP = N-acetyl-D-glucosamine 6-phosphate + UDP + H(+)

Direction not assertedBalancedRhea 74659

acetylcholine(in) = acetylcholine(out)

ReversibleBalancedTransportRhea 74663

(6S)-6-amino-3,3-dimethyl-2-oxoheptanedioate = (2S)-5,5-dimethyl-2,3,4,5-tetrahydropyridine-2,6-dicarboxylate + H2O + H(+)

Direction not assertedBalancedRhea 74667

UDP-beta-L-arabinopyranose(in) + UMP(out) = UDP-beta-L-arabinopyranose(out) + UMP(in)

Direction not assertedBalancedTransportRhea 74671

archaeol + AH2 + 2 S-adenosyl-L-methionine = macrocyclic archaeol + 2 5'-deoxyadenosine + 2 L-methionine + A + 2 H(+)

Direction not assertedBalancedRhea 74675

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