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CompoundsSubstances with curated findings
OutcomesMeasured endpoints
ProteinsTransporters and enzymes
InteractionsPairs that share biology
PapersEvery paper a finding cites
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Chemistry

ReactionsRhea and Human-GEM, by subsystem
ReachWhat a compound can become

Reference layer

PathwaysReactions grouped under one name
ProcessesWhat proteins are annotated as doing
AnatomyTissues, by what is expressed there
Cell typesCells, by what is expressed there
OrganismsSpecies a compound is prepared from
MaterialsSubstances that are not one molecule
AssessmentsRegulatory determinations, transcribed
DiseasesFeatures, genes, and where each sits

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Reference

Evidence

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Computational infrastructure for human biology, built on a provenance-aware knowledge graph. Findings retain their sources; research and simulation are the next layers.

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A reference for what the literature reports. Not medical advice.

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Index

Reactions

Reactions from Rhea and Human-GEM · Reach

reactions in the graph: 31,435

By source

Rhea18,558
Human-GEM12,877

Inferred

Reference data, not a finding. Evidence key

Filter reactions by equationSource

Reactions

28,351–28,400 of 31,435, by identifier

a lipid IVA + a 1,2-diacyl-sn-glycero-3-phosphocholine = a lipid IVB + a 2-acyl-sn-glycero-3-phosphocholine
Direction not assertedBalance undeterminableRhea 74279
a lipid IIA + a 1,2-diacyl-sn-glycero-3-phosphocholine = a lipid IIB + a 2-acyl-sn-glycero-3-phosphocholine
Direction not assertedBalance undeterminableRhea 74283
an alpha-Kdo-(2->4)-alpha-Kdo-(2->6)-lipid IVA + a fatty acyl-[ACP] = an acyl-alpha-Kdo-(2->4)-alpha-Kdo-(2->6)-lipid IVA + holo-[ACP]
Direction not assertedBalance undeterminableRhea 74287
an alpha-Kdo-(2->4)-alpha-Kdo-(2->6)-lipid A + di-trans,octa-cis-undecaprenyl diphosphate = an alpha-D-Kdo-(2->4)-alpha-D-Kdo-(2->6)-lipid A 1-diphosphate + di-trans,octa-cis-undecaprenyl phosphate
Direction not assertedBalance undeterminableRhea 74291
serotonin(in) + n H(+)(out) = serotonin(out) + n H(+)(in)
Left to rightBalance undeterminableTransportRhea 74295
D-isoleucine(out) + D-serine(in) = D-isoleucine(in) + D-serine(out)
Left to right

→

Balanced

Transport

Rhea 74299

12alpha-hydroxy-3-oxochola-4-en-24-oate + NAD(+) = 12alpha-hydroxy-3-oxochola-4,6-dien-24-oate + NADH + H(+)

Direction not assertedBalancedRhea 74303

12alpha-hydroxy-3-oxo-5beta-cholan-24-oate + NAD(+) = 12alpha-hydroxy-3-oxochola-4-en-24-oate + NADH + H(+)

Direction not assertedBalancedRhea 74307

12alpha-hydroxy-3-oxochola-4,6-dien-24-oyl-CoA + H2O = 12alpha-hydroxy-3-oxochola-4,6-dien-24-oate + CoA + H(+)

Direction not assertedBalancedRhea 74311

O-isobutanoyl-(R)-carnitine(in) = O-isobutanoyl-(R)-carnitine(out)

Direction not assertedBalancedTransportRhea 74315

O-acetyl-(R)-carnitine(in) = O-acetyl-(R)-carnitine(out)

ReversibleBalancedTransportRhea 74319

O-3-hydroxybutanoyl-(R)-carnitine(in) = O-3-hydroxybutanoyl-(R)-carnitine(out)

Direction not assertedBalancedTransportRhea 74323

O-propanoyl-(R)-carnitine(in) = O-propanoyl-(R)-carnitine(out)

Direction not assertedBalancedTransportRhea 74327

O-butanoyl-(R)-carnitine(in) = O-butanoyl-(R)-carnitine(out)

Direction not assertedBalancedTransportRhea 74331

O-2-methylbutanoyl-(R)-carnitine(in) = O-2-methylbutanoyl-(R)-carnitine(out)

Direction not assertedBalancedTransportRhea 74335

O-3-methylbutanoyl-(R)-carnitine(in) = O-3-methylbutanoyl-(R)-carnitine(out)

Direction not assertedBalancedTransportRhea 74339

O-hexanoyl-(R)-carnitine(in) = O-hexanoyl-(R)-carnitine(out)

Direction not assertedBalancedTransportRhea 74343

an O-acyl-(R)-carnitine(in) = an O-acyl-(R)-carnitine(out)

Direction not assertedBalance undeterminableTransportRhea 74347

prostaglandin E3(out) + 2 (S)-lactate(in) = prostaglandin E3(in) + 2 (S)-lactate(out)

Direction not assertedBalancedTransportRhea 74351

a cytidine in mRNA + H2O + H(+) = a uridine in mRNA + NH4(+)

Left to rightBalance undeterminableRhea 74355

coproporphyrin I(out) = coproporphyrin I(in)

Direction not assertedBalancedTransportRhea 74359

coproporphyrin III(out) = coproporphyrin III(in)

Direction not assertedBalancedTransportRhea 74363

substance P(out) = substance P(in)

Direction not assertedBalancedTransportRhea 74367

nicotinate(in) + a carboxylate(out) = nicotinate(out) + a carboxylate(in)

Direction not assertedBalance undeterminableTransportRhea 74371

H2O2(out) = H2O2(in)

Direction not assertedBalancedTransportRhea 74375

prostaglandin H2(out) + 2 (S)-lactate(in) = prostaglandin H2(in) + 2 (S)-lactate(out)

Direction not assertedBalancedTransportRhea 74379

prostaglandin E2(out) + 2 (S)-lactate(in) = prostaglandin E2(in) + 2 (S)-lactate(out)

Direction not assertedBalancedTransportRhea 74383

formamide(out) = formamide(in)

Direction not assertedBalancedTransportRhea 74387

methylamine(out) = methylamine(in)

Left to rightBalancedTransportRhea 74391

prostaglandin E1(out) + 2 (S)-lactate(in) = prostaglandin E1(in) + 2 (S)-lactate(out)

Direction not assertedBalancedTransportRhea 74395

prostaglandin F2alpha(out) + 2 (S)-lactate(in) = prostaglandin F2alpha(in) + 2 (S)-lactate(out)

Direction not assertedBalancedTransportRhea 74399

prostaglandin D2(out) + 2 (S)-lactate(in) = prostaglandin D2(in) + 2 (S)-lactate(out)

Direction not assertedBalancedTransportRhea 74403

thromboxane B2(out) + 2 (S)-lactate(in) = thromboxane B2(in) + 2 (S)-lactate(out)

Direction not assertedBalancedTransportRhea 74407

1-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine(out) + H(+)(out) = 1-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine(in) + H(+)(in)

Direction not assertedBalancedTransportRhea 74411

1-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine(out) + H(+)(out) = 1-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine(in) + H(+)(in)

Direction not assertedBalancedTransportRhea 74415

1-(9Z-octadecenoyl)-sn-glycero-3-phospho-(1'-sn-glycerol)(out) + H(+)(out) = 1-(9Z-octadecenoyl)-sn-glycero-3-phospho-(1'-sn-glycerol)(in) + H(+)(in)

Direction not assertedBalancedTransportRhea 74419

1-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphocholine(out) + H(+)(out) = 1-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphocholine(in) + H(+)(in)

Direction not assertedBalancedTransportRhea 74423

1-hexadecanoyl-sn-glycero-3-phosphocholine(out) + H(+)(out) = 1-hexadecanoyl-sn-glycero-3-phosphocholine(in) + H(+)(in)

Direction not assertedBalancedTransportRhea 74427

1-(1Z-hexadecenyl)-sn-glycero-3-phosphocholine(out) + H(+)(out) = 1-(1Z-hexadecenyl)-sn-glycero-3-phosphocholine(in) + H(+)(in)

Direction not assertedBalancedTransportRhea 74431

a 1-acyl-sn-glycero-3-phosphocholine(out) + H(+)(out) = a 1-acyl-sn-glycero-3-phosphocholine(in) + H(+)(in)

Direction not assertedBalance undeterminableTransportRhea 74435

a 1-acyl-sn-glycero-3-phosphoethanolamine(out) + H(+)(out) = a 1-acyl-sn-glycero-3-phosphoethanolamine(in) + H(+)(in)

Direction not assertedBalance undeterminableTransportRhea 74439

1-acyl-sn-glycero-3-phospho-(1'-sn-glycerol)(out) + H(+)(out) = 1-acyl-sn-glycero-3-phospho-(1'-sn-glycerol)(in) + H(+)(in)

Direction not assertedBalance undeterminableTransportRhea 74443

a 1-O-(1Z-alkenyl)-sn-glycero-3-phosphocholine(out) + H(+)(out) = a 1-O-(1Z-alkenyl)-sn-glycero-3-phosphocholine(in) + H(+)(in)

Direction not assertedBalance undeterminableTransportRhea 74447

1-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphocholine(out) + H(+)(out) = 1-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphocholine(in) + H(+)(in)

Direction not assertedBalancedTransportRhea 74451

a 1-O-(1Z-alkenyl)-sn-glycero-3-phosphoethanolamine(out) + H(+)(out) = a 1-O-(1Z-alkenyl)-sn-glycero-3-phosphoethanolamine(in) + H(+)(in)

Direction not assertedBalance undeterminableTransportRhea 74455

1-O-(1Z-hexadecenyl)-sn-glycero-3-phosphoethanolamine(out) + H(+)(out) = 1-O-(1Z-hexadecenyl)-sn-glycero-3-phosphoethanolamine(in) + H(+)(in)

Direction not assertedBalancedTransportRhea 74459

(-)-4'-methoxycyclopenine = 4'-methoxyviridicatin + methyl isocyanate + H(+)

Direction not assertedBalancedRhea 74463

a 1-O-alkyl-2-acyl-3-(beta-D-3-sulfogalactosyl)-sn-glycerol + H2O = a 1-O-alkyl-2-acyl-3-O-(beta-D-galactosyl)-sn-glycerol + sulfate + H(+)

Direction not assertedBalance undeterminableRhea 74467

(-)-4'-methoxycyclopeptine + 2-oxoglutarate + O2 = (Z)-4'-methoxydehydrocyclopeptine + succinate + CO2 + H2O

Direction not assertedBalancedRhea 74471

(Z)-4'-methoxydehydrocyclopeptine + 2-oxoglutarate + O2 = (-)-4'-methoxycyclopenine + succinate + CO2

Direction not assertedBalancedRhea 74475

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