Skip to content

Reference

Evidence

CompoundsSubstances with curated findings
OutcomesMeasured endpoints
ProteinsTransporters and enzymes
InteractionsPairs that share biology
PapersEvery paper a finding cites
ArticlesReadings of the evidence

Chemistry

ReactionsRhea and Human-GEM, by subsystem
ReachWhat a compound can become

Reference layer

PathwaysReactions grouped under one name
ProcessesWhat proteins are annotated as doing
AnatomyTissues, by what is expressed there
Cell typesCells, by what is expressed there
OrganismsSpecies a compound is prepared from
MaterialsSubstances that are not one molecule
AssessmentsRegulatory determinations, transcribed
DiseasesFeatures, genes, and where each sits

Atlas Graph Twin Access

Search the graph

Reference

Evidence

Compounds
Outcomes
Proteins
Interactions
Papers
Articles

Chemistry

Reactions
Reach

Reference layer

Pathways
Processes
Anatomy
Cell types
Organisms
Materials
Assessments
Diseases

Atlas Graph Twin Access

Loading the page.

Catalyst

Computational infrastructure for human biology, built on a provenance-aware knowledge graph. Findings retain their sources; research and simulation are the next layers.

The graph

Compounds
Outcomes
Proteins
Atlas
Interactions
Papers
Articles
Graph
Search

Reference layer

Pathways
Processes
Anatomy
Cell types
Organisms
Materials
Assessments
Diseases
Reactions
Reach

How it works

Mission
Method
Twin
How to read the evidence
Sources and licences

Build on it

Access
In your assistant
For agents
Query the graph
Bulk export

A reference for what the literature reports. Not medical advice.

© 2026 CatalystPrivacy TermsReference data under the licences listed on the attribution page.

Index

Reactions

Reactions from Rhea and Human-GEM · Reach

reactions in the graph: 31,435

By source

Rhea18,558
Human-GEM12,877

Inferred

Reference data, not a finding. Evidence key

Filter reactions by equationSource

Reactions

27,951–28,000 of 31,435, by identifier

secologanin + reduced [NADPH--hemoprotein reductase] + O2 = secoxyloganin + oxidized [NADPH--hemoprotein reductase] + H2O + 2 H(+)
Direction not assertedBalance undeterminableRhea 72667
6-hydroxyphenazine-1-carboxylate + NADH + O2 + 2 H(+) = 1,6-dihydroxyphenazine + CO2 + NAD(+) + H2O
Direction not assertedBalancedRhea 72671
3',5'-cyclic CMP + H2O = CMP + H(+)
Direction not assertedBalancedRhea 72675
(R)-dihydrolipoate + L-lysyl-[lipoyl-carrier protein] + ATP = N(6)-[(R)-dihydrolipoyl]-L-lysyl-[lipoyl-carrier protein] + AMP + diphosphate + H(+)
Direction not assertedBalance undeterminableRhea 72679
cholate(out) = cholate(in)
Direction not assertedBalancedTransportRhea 72683
all-trans-retinol(out) = all-trans-retinol(in)
Direction not assertedBalancedTransportRhea 72687

17beta-estradiol 17-O-(beta-D-glucuronate)(out) = 17beta-estradiol 17-O-(beta-D-glucuronate)(in)

Left to rightBalancedTransportRhea 72691

UMP(out) + UDP-N-acetyl-alpha-D-glucosamine(in) = UMP(in) + UDP-N-acetyl-alpha-D-glucosamine(out)

Direction not assertedBalancedTransportRhea 72695

acrylate + NADH + H(+) = propanoate + NAD(+)

Direction not assertedBalancedRhea 72699

UMP(out) + UDP-alpha-D-galactose(in) = UMP(in) + UDP-alpha-D-galactose(out)

Direction not assertedBalancedTransportRhea 72703

GMP(out) + GDP-beta-L-fucose(in) = GMP(in) + GDP-beta-L-fucose(out)

Direction not assertedBalancedTransportRhea 72707

cathenamine + H(+) = 4,21-dehydrogeissoschizine

Direction not assertedBalancedRhea 72711

(R)-dihydrolipoate + ATP + H(+) = N(6)-[(R)-dihydrolipoyl]-5'-AMP + diphosphate

Direction not assertedBalancedRhea 72715

N(6)-[(R)-dihydrolipoyl]-5'-AMP + L-lysyl-[lipoyl-carrier protein] = N(6)-[(R)-dihydrolipoyl]-L-lysyl-[lipoyl-carrier protein] + AMP + 2 H(+)

Direction not assertedBalance undeterminableRhea 72719

UDP-alpha-D-xylose(in) + UMP(out) = UDP-alpha-D-xylose(out) + UMP(in)

Direction not assertedBalancedTransportRhea 72723

UMP(out) + UDP-alpha-D-glucuronate(in) = UMP(in) + UDP-alpha-D-glucuronate(out)

Direction not assertedBalancedTransportRhea 72727

UMP(out) + UDP-alpha-D-glucose(in) = UMP(in) + UDP-alpha-D-glucose(out)

Direction not assertedBalancedTransportRhea 72731

UDP-N-acetyl-alpha-D-galactosamine(in) + UMP(out) = UDP-N-acetyl-alpha-D-galactosamine(out) + UMP(in)

Direction not assertedBalancedTransportRhea 72735

2 hydrogencarbonate(out) + chloride(in) + Na(+)(out) = 2 hydrogencarbonate(in) + chloride(out) + Na(+)(in)

Direction not assertedBalancedTransportRhea 72739

leukotriene C4(out) = leukotriene C4(in)

Direction not assertedBalancedTransportRhea 72743

leukotriene E4(out) = leukotriene E4(in)

Direction not assertedBalancedTransportRhea 72747

ochratoxin A + H2O = ochratoxin alpha + L-phenylalanine

Direction not assertedBalancedRhea 72751

3 ATP = 3',3',3'-c-tri-AMP + 3 diphosphate

Direction not assertedBalancedRhea 72755

anthocyanin A6 + malonyl-CoA = anthocyanin A8 + CoA

Direction not assertedBalancedRhea 72759

anthocyanin A10 + malonyl-CoA = anthocyanin A11 + CoA

Direction not assertedBalancedRhea 72763

4 malonyl-CoA + acetyl-CoA + 5 NADPH + 9 H(+) = 7-methylmellein + 3 CO2 + 5 NADP(+) + 5 CoA + 4 H2O

Direction not assertedBalancedRhea 72767

7-methylmellein + 3 reduced [NADPH--hemoprotein reductase] + 3 O2 = 7-carboxymellein + 3 oxidized [NADPH--hemoprotein reductase] + 4 H2O + 4 H(+)

Direction not assertedBalance undeterminableRhea 72771

7-carboxymellein + L-phenylalanine + ATP = ochratoxin B + ADP + phosphate + H(+)

Direction not assertedBalancedRhea 72775

ochratoxin B + FADH2 + chloride + O2 = ochratoxin A + FAD + 2 H2O

Direction not assertedBalancedRhea 72779

N-carbamoyl-L-methionine + H2O + 2 H(+) = L-methionine + NH4(+) + CO2

Direction not assertedBalancedRhea 72783

N-carbamoyl-L-cysteine + H2O + 2 H(+) = L-cysteine + NH4(+) + CO2

Direction not assertedBalancedRhea 72787

(4E,15E)-bilirubin IXalpha C8-beta-D-glucuronoside(out) = (4E,15E)-bilirubin IXalpha C8-beta-D-glucuronoside(in)

Direction not assertedBalancedTransportRhea 72791

bilirubin IXalpha bis-beta-D-glucuronoside(out) = bilirubin IXalpha bis-beta-D-glucuronoside(in)

Direction not assertedBalancedTransportRhea 72795

L-homoarginine(in) + L-arginine(out) = L-homoarginine(out) + L-arginine(in)

Direction not assertedBalancedTransportRhea 72799

N(omega)-methyl-L-arginine(in) + L-arginine(out) = N(omega)-methyl-L-arginine(out) + L-arginine(in)

Direction not assertedBalancedTransportRhea 72803

L-histidine(out) = L-histidine(in)

Direction not assertedBalancedTransportRhea 72807

N(omega),N(omega)-dimethyl-L-arginine(in) + L-arginine(out) = N(omega),N(omega)-dimethyl-L-arginine(out) + L-arginine(in)

Direction not assertedBalancedTransportRhea 72811

N(omega),N(omega)-dimethyl-L-arginine(in) + L-lysine(out) = N(omega),N(omega)-dimethyl-L-arginine(out) + L-lysine(in)

Direction not assertedBalancedTransportRhea 72815

N(omega),N(omega)-dimethyl-L-arginine(in) + L-ornithine(out) = N(omega),N(omega)-dimethyl-L-arginine(out) + L-ornithine(in)

Direction not assertedBalancedTransportRhea 72819

N-carbamoyl-L-tryptophan + H2O + 2 H(+) = L-tryptophan + NH4(+) + CO2

Direction not assertedBalancedRhea 72823

N-carbamoyl-L-alanine + H2O + 2 H(+) = L-alanine + NH4(+) + CO2

Direction not assertedBalancedRhea 72827

3',3'-cGAMP + H2O = G[3'-5']pAp[3'] + H(+)

Direction not assertedBalancedRhea 72831

3',3'-cUAMP + H2O = U[3'-5']pAp[3'] + H(+)

Direction not assertedBalancedRhea 72835

ADP(out) + CoA(in) = ADP(in) + CoA(out)

Direction not assertedBalancedTransportRhea 72839

3'-dephospho-CoA(in) + ADP(out) = 3'-dephospho-CoA(out) + ADP(in)

Direction not assertedBalancedTransportRhea 72843

adenosine 3',5'-bisphosphate(in) + ADP(out) = adenosine 3',5'-bisphosphate(out) + ADP(in)

Direction not assertedBalancedTransportRhea 72847

AMP(in) + ADP(out) = AMP(out) + ADP(in)

Direction not assertedBalancedTransportRhea 72851

dADP(in) + ADP(out) = dADP(out) + ADP(in)

ReversibleBalancedTransportRhea 72855

3',3',3'-c-tri-AMP + H2O = A[3'-5']pA[3'-5']pAp[3'] + H(+)

Direction not assertedBalancedRhea 72859

3',3',3'-cAAG + H2O = G[3'-5']pA[3'-5']pAp[3'] + H(+)

Direction not assertedBalancedRhea 72863

Page 560 of 629