Skip to content

Reference

Evidence

CompoundsSubstances with curated findings
OutcomesMeasured endpoints
ProteinsTransporters and enzymes
InteractionsPairs that share biology
PapersEvery paper a finding cites
ArticlesReadings of the evidence

Chemistry

ReactionsRhea and Human-GEM, by subsystem
ReachWhat a compound can become

Reference layer

PathwaysReactions grouped under one name
ProcessesWhat proteins are annotated as doing
AnatomyTissues, by what is expressed there
Cell typesCells, by what is expressed there
OrganismsSpecies a compound is prepared from
MaterialsSubstances that are not one molecule
AssessmentsRegulatory determinations, transcribed
DiseasesFeatures, genes, and where each sits

Atlas Graph Twin Access

Search the graph

Reference

Evidence

Compounds
Outcomes
Proteins
Interactions
Papers
Articles

Chemistry

Reactions
Reach

Reference layer

Pathways
Processes
Anatomy
Cell types
Organisms
Materials
Assessments
Diseases

Atlas Graph Twin Access

Loading the page.

Catalyst

Computational infrastructure for human biology, built on a provenance-aware knowledge graph. Findings retain their sources; research and simulation are the next layers.

The graph

Compounds
Outcomes
Proteins
Atlas
Interactions
Papers
Articles
Graph
Search

Reference layer

Pathways
Processes
Anatomy
Cell types
Organisms
Materials
Assessments
Diseases
Reactions
Reach

How it works

Mission
Method
Twin
How to read the evidence
Sources and licences

Build on it

Access
In your assistant
For agents
Query the graph
Bulk export

A reference for what the literature reports. Not medical advice.

© 2026 CatalystPrivacy TermsReference data under the licences listed on the attribution page.

Index

Reactions

Reactions from Rhea and Human-GEM · Reach

reactions in the graph: 31,435

By source

Rhea18,558
Human-GEM12,877

Inferred

Reference data, not a finding. Evidence key

Filter reactions by equationSource

Reactions

28,001–28,050 of 31,435, by identifier

3',3',3'-cAAG + H2O = A[3'-5']pG[3'-5']pAp[3'] + H(+)
Direction not assertedBalancedRhea 72867
anthocyanin A3 + malonyl-CoA = anthocyanin A5 + CoA
Direction not assertedBalancedRhea 72871
anthocyanin A7 + malonyl-CoA = anthocyanin A9 + CoA
Direction not assertedBalancedRhea 72875
(1R)-(2-amino-1-hydroxyethyl)phosphonate = phosphonoacetaldehyde + NH4(+)
Direction not assertedBalancedRhea 72879
2 3-phenylpyruvate + 2 ATP = polyporic acid + 2 AMP + 2 diphosphate + H(+)
Direction not assertedBalancedRhea 72883
polyporic acid + reduced [NADPH--hemoprotein reductase] + O2 = ascocorynin + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)
Direction not assertedBalance undeterminableRhea 72887
acetylcholine(out) + 2 H(+)(in) = acetylcholine(in) + 2 H(+)(out)

Left to rightBalancedTransportRhea 72891

6 malonyl-CoA + 2 acetyl-CoA + 2 S-adenosyl-L-methionine + 3 H(+) = 4-O-demethylbarbatate + 2 S-adenosyl-L-homocysteine + 6 CO2 + 8 CoA + H2O

Direction not assertedBalancedRhea 72895

4-O-demethylbarbatate + S-adenosyl-L-methionine = proatranorin I + S-adenosyl-L-homocysteine

Direction not assertedBalancedRhea 72899

butyrolactone II + dimethylallyl diphosphate = butyrolactone I + diphosphate

Direction not assertedBalancedRhea 72903

D-mannose(out) + Na(+)(out) = D-mannose(in) + Na(+)(in)

Left to rightBalancedTransportRhea 72907

proatranorin III + S-adenosyl-L-methionine = atranorin + S-adenosyl-L-homocysteine

Direction not assertedBalancedRhea 72911

D-fructopyranose(out) + Na(+)(out) = D-fructopyranose(in) + Na(+)(in)

Left to rightBalancedTransportRhea 72915

4-O-demethylbarbatate + reduced [NADPH--hemoprotein reductase] + O2 = proatranorin II + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Direction not assertedBalance undeterminableRhea 72919

proatranorin II + reduced [NADPH--hemoprotein reductase] + O2 = proatranorin III + oxidized [NADPH--hemoprotein reductase] + 2 H2O + H(+)

Direction not assertedBalance undeterminableRhea 72923

proatranorin I + reduced [NADPH--hemoprotein reductase] + O2 = proatranorin IV + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Direction not assertedBalance undeterminableRhea 72927

proatranorin IV + reduced [NADPH--hemoprotein reductase] + O2 = atranorin + oxidized [NADPH--hemoprotein reductase] + 2 H2O + H(+)

Direction not assertedBalance undeterminableRhea 72931

(S)-lactate(out) + 2 Na(+)(out) = (S)-lactate(in) + 2 Na(+)(in)

Direction not assertedBalancedTransportRhea 72935

propanoate(out) + 2 Na(+)(out) = propanoate(in) + 2 Na(+)(in)

Direction not assertedBalancedTransportRhea 72939

pyruvate(out) + 2 Na(+)(out) = pyruvate(in) + 2 Na(+)(in)

Direction not assertedBalancedTransportRhea 72943

acetate(out) + 2 Na(+)(out) = acetate(in) + 2 Na(+)(in)

Direction not assertedBalancedTransportRhea 72947

butanoate(out) + 2 Na(+)(out) = butanoate(in) + 2 Na(+)(in)

Direction not assertedBalancedTransportRhea 72951

nicotinate(out) + 2 Na(+)(out) = nicotinate(in) + 2 Na(+)(in)

Direction not assertedBalancedTransportRhea 72955

(R)-3-hydroxybutanoate(out) + 2 Na(+)(out) = (R)-3-hydroxybutanoate(in) + 2 Na(+)(in)

Direction not assertedBalancedTransportRhea 72959

acetoacetate(out) + 2 Na(+)(out) = acetoacetate(in) + 2 Na(+)(in)

Direction not assertedBalancedTransportRhea 72963

4-methyl-2-oxopentanoate(out) + 2 Na(+)(out) = 4-methyl-2-oxopentanoate(in) + 2 Na(+)(in)

Direction not assertedBalancedTransportRhea 72967

5-oxo-L-proline(out) + 2 Na(+)(out) = 5-oxo-L-proline(in) + 2 Na(+)(in)

Direction not assertedBalancedTransportRhea 72971

2 indole-3-pyruvate + 2 ATP = didemethylasterriquinone D + 2 AMP + 2 diphosphate + H(+)

Direction not assertedBalancedRhea 72975

didemethylasterriquinone D + dimethylallyl diphosphate = asterriquinone C1 + diphosphate

Direction not assertedBalancedRhea 72979

harmol + dimethylallyl diphosphate = 6-(3-dimethylallyl)harmol + diphosphate

Direction not assertedBalancedRhea 72983

myo-inositol(out) + 2 Na(+)(out) = myo-inositol(in) + 2 Na(+)(in)

Direction not assertedBalancedTransportRhea 72987

scyllo-inositol(out) + 2 Na(+)(out) = scyllo-inositol(in) + 2 Na(+)(in)

Direction not assertedBalancedTransportRhea 72991

L-fucose(out) + 2 Na(+)(out) = L-fucose(in) + 2 Na(+)(in)

Direction not assertedBalancedTransportRhea 72995

an N-terminal L-tryptophanyl-L-alpha-aminoacyl-[peptide] + H2O = an N-terminal L-alpha-aminoacyl-[peptide] + L-tryptophan

Direction not assertedBalance undeterminableRhea 72999

anthranilate + L-tryptophan + 2 ATP = (R)-benzodiazepinedione + 2 AMP + 2 diphosphate + H(+)

Direction not assertedBalancedRhea 73003

D-arabinose 5-phosphate = glycolaldehyde + D-glyceraldehyde 3-phosphate

Direction not assertedBalancedRhea 73007

L-leucine(in) = L-leucine(out)

Right to leftBalancedTransportRhea 73011

D-leucine(in) = D-leucine(out)

Direction not assertedBalancedTransportRhea 73015

pregnenolone sulfate(out) = pregnenolone sulfate(in)

Direction not assertedBalancedTransportRhea 73023

Cd(2+)(out) + H(+)(out) = Cd(2+)(in) + H(+)(in)

Left to rightBalancedTransportRhea 73031

Co(2+)(out) + H(+)(out) = Co(2+)(in) + H(+)(in)

Left to rightBalancedTransportRhea 73035

Ni(2+)(out) + H(+)(out) = Ni(2+)(in) + H(+)(in)

Left to rightBalancedTransportRhea 73039

creatine(in) = creatine(out)

Right to leftBalancedTransportRhea 73043

guanidinoacetate(in) = guanidinoacetate(out)

Direction not assertedBalancedTransportRhea 73047

taurocholate(out) + hydrogencarbonate(in) = taurocholate(in) + hydrogencarbonate(out)

Direction not assertedBalancedTransportRhea 73051

estrone 3-sulfate(out) + hydrogencarbonate(in) = estrone 3-sulfate(in) + hydrogencarbonate(out)

Direction not assertedBalancedTransportRhea 73055

Mn(2+)(out) + Ca(2+)(in) = Mn(2+)(in) + Ca(2+)(out)

Direction not assertedBalancedTransportRhea 73059

Mn(2+)(in) + H(+)(out) = Mn(2+)(out) + H(+)(in)

Direction not assertedBalancedTransportRhea 73063

an N(4)-(oligosaccharide-(1->3)-[oligosaccharide-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-alpha-D-GlcNAc)-L-asparaginyl-[protein] + H2O = an oligosaccharide-(1->3)-[oligosaccharide-(1->6)]-beta-D-Man-(1->4)-D-GlcNAc + N(4)-(N-acetyl-beta-D-glucosaminyl)-L-asparaginyl-[protein]

Direction not assertedBalance undeterminableRhea 73067

apigenin + S-adenosyl-L-methionine = genkwanin + S-adenosyl-L-homocysteine + H(+)

Direction not assertedBalancedRhea 73071

Page 561 of 629