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CompoundsSubstances with curated findings
OutcomesMeasured endpoints
ProteinsTransporters and enzymes
InteractionsPairs that share biology
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ReactionsRhea and Human-GEM, by subsystem
ReachWhat a compound can become

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PathwaysReactions grouped under one name
ProcessesWhat proteins are annotated as doing
AnatomyTissues, by what is expressed there
Cell typesCells, by what is expressed there
OrganismsSpecies a compound is prepared from
MaterialsSubstances that are not one molecule
AssessmentsRegulatory determinations, transcribed
DiseasesFeatures, genes, and where each sits

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Reference

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Computational infrastructure for human biology, built on a provenance-aware knowledge graph. Findings retain their sources; research and simulation are the next layers.

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A reference for what the literature reports. Not medical advice.

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Index

Reactions

Reactions from Rhea and Human-GEM · Reach

reactions in the graph: 31,435

By source

Rhea18,558
Human-GEM12,877

Inferred

Reference data, not a finding. Evidence key

Filter reactions by equationSource

Reactions

27,601–27,650 of 31,435, by identifier

L-pipecolate(out) + chloride(out) + 2 Na(+)(out) = L-pipecolate(in) + chloride(in) + 2 Na(+)(in)
Direction not assertedBalancedTransportRhea 71267
thiamine(out) + H(+)(in) = thiamine(in) + H(+)(out)
Direction not assertedBalancedTransportRhea 71271
taurolithocholate 3-sulfate(out) + 2 Na(+)(out) = taurolithocholate 3-sulfate(in) + 2 Na(+)(in)
Direction not assertedBalancedTransportRhea 71275
L-leucine(out) + chloride(out) + 2 Na(+)(out) = L-leucine(in) + chloride(in) + 2 Na(+)(in)
Direction not assertedBalancedTransportRhea 71279
L-glutamine(out) + chloride(out) + 2 Na(+)(out) = L-glutamine(in) + chloride(in) + 2 Na(+)(in)
Direction not assertedBalancedTransportRhea 71283
L-arginine(out) + chloride(out) + 2 Na(+)(out) = L-arginine(in) + chloride(in) + 2 Na(+)(in)
Direction not assertedBalanced

Transport

Rhea 71287

(R)-carnitine(out) + chloride(out) + 2 Na(+)(out) = (R)-carnitine(in) + chloride(in) + 2 Na(+)(in)

Direction not assertedBalancedTransportRhea 71291

O-propanoyl-(R)-carnitine(out) + chloride(out) + 2 Na(+)(out) = O-propanoyl-(R)-carnitine(in) + chloride(in) + 2 Na(+)(in)

Direction not assertedBalancedTransportRhea 71295

L-isoleucine(out) + chloride(out) + 2 Na(+)(out) = L-isoleucine(in) + chloride(in) + 2 Na(+)(in)

Direction not assertedBalancedTransportRhea 71299

L-methionine(out) + chloride(out) + 2 Na(+)(out) = L-methionine(in) + chloride(in) + 2 Na(+)(in)

Direction not assertedBalancedTransportRhea 71303

L-valine(out) + chloride(out) + 2 Na(+)(out) = L-valine(in) + chloride(in) + 2 Na(+)(in)

Direction not assertedBalancedTransportRhea 71307

L-alanine(out) + chloride(out) + 2 Na(+)(out) = L-alanine(in) + chloride(in) + 2 Na(+)(in)

Direction not assertedBalancedTransportRhea 71311

L-serine(out) + chloride(out) + 2 Na(+)(out) = L-serine(in) + chloride(in) + 2 Na(+)(in)

Direction not assertedBalancedTransportRhea 71315

L-cysteine(out) + chloride(out) + 2 Na(+)(out) = L-cysteine(in) + chloride(in) + 2 Na(+)(in)

Direction not assertedBalancedTransportRhea 71319

L-asparagine(out) + chloride(out) + 2 Na(+)(out) = L-asparagine(in) + chloride(in) + 2 Na(+)(in)

Direction not assertedBalancedTransportRhea 71323

L-threonine(out) + chloride(out) + 2 Na(+)(out) = L-threonine(in) + chloride(in) + 2 Na(+)(in)

Direction not assertedBalancedTransportRhea 71327

L-phenylalanine(out) + chloride(out) + 2 Na(+)(out) = L-phenylalanine(in) + chloride(in) + 2 Na(+)(in)

Direction not assertedBalancedTransportRhea 71331

L-tryptophan(out) + chloride(out) + 2 Na(+)(out) = L-tryptophan(in) + chloride(in) + 2 Na(+)(in)

Direction not assertedBalancedTransportRhea 71335

L-tyrosine(out) + chloride(out) + 2 Na(+)(out) = L-tyrosine(in) + chloride(in) + 2 Na(+)(in)

Direction not assertedBalancedTransportRhea 71339

L-histidine(out) + chloride(out) + 2 Na(+)(out) = L-histidine(in) + chloride(in) + 2 Na(+)(in)

Direction not assertedBalancedTransportRhea 71343

L-lysine(out) + chloride(out) + 2 Na(+)(out) = L-lysine(in) + chloride(in) + 2 Na(+)(in)

Direction not assertedBalancedTransportRhea 71347

androsterone 3alpha-sulfate(out) + 2 Na(+)(out) = androsterone 3alpha-sulfate(in) + 2 Na(+)(in)

Direction not assertedBalancedTransportRhea 71351

5alpha-dihydrotestosterone sulfate(out) + 2 Na(+)(out) = 5alpha-dihydrotestosterone sulfate(in) + 2 Na(+)(in)

Direction not assertedBalancedTransportRhea 71355

17beta-estradiol 17-sulfate(out) + 2 Na(+)(out) = 17beta-estradiol 17-sulfate(in) + 2 Na(+)(in)

Direction not assertedBalancedTransportRhea 71359

17alpha-hydroxypregnenolone 3-sulfate(out) + 2 Na(+)(out) = 17alpha-hydroxypregnenolone 3-sulfate(in) + 2 Na(+)(in)

Direction not assertedBalancedTransportRhea 71363

epiandrosterone 3-sulfate(out) + 2 Na(+)(out) = epiandrosterone 3-sulfate(in) + 2 Na(+)(in)

Direction not assertedBalancedTransportRhea 71367

epitestosterone 17-sulfate(out) + 2 Na(+)(out) = epitestosterone 17-sulfate(in) + 2 Na(+)(in)

Direction not assertedBalancedTransportRhea 71371

testosterone 17-sulfate(out) + 2 Na(+)(out) = testosterone 17-sulfate(in) + 2 Na(+)(in)

Direction not assertedBalancedTransportRhea 71375

D-aspartate(out) + K(+)(in) + 3 Na(+)(out) + H(+)(out) = D-aspartate(in) + K(+)(out) + 3 Na(+)(in) + H(+)(in)

Direction not assertedBalancedTransportRhea 71379

L-asparagine(in) + Na(+)(in) = L-asparagine(out) + Na(+)(out)

Right to leftBalancedTransportRhea 71383

L-pipecolate(in) + Na(+)(in) = L-pipecolate(out) + Na(+)(out)

Direction not assertedBalancedTransportRhea 71387

16alpha-hydroxydehydroepiandrosterone 3-sulfate(out) + 2 Na(+)(out) = 16alpha-hydroxydehydroepiandrosterone 3-sulfate(in) + 2 Na(+)(in)

Direction not assertedBalancedTransportRhea 71391

(5Z,8Z,11Z,14Z)-eicosatetraenoate(out) = (5Z,8Z,11Z,14Z)-eicosatetraenoate(in)

Left to rightBalancedTransportRhea 71395

taxusin + reduced [NADPH--hemoprotein reductase] + O2 = 2alpha-hydroxytaxusin + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Direction not assertedBalance undeterminableRhea 71399

2alpha-hydroxytaxusin + reduced [NADPH--hemoprotein reductase] + O2 = 2alpha,7beta-dihydroxytaxusin + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Direction not assertedBalance undeterminableRhea 71403

7beta-hydroxytaxusin + reduced [NADPH--hemoprotein reductase] + O2 = 2alpha,7beta-dihydroxytaxusin + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Direction not assertedBalance undeterminableRhea 71407

3,3',5-triiodo-L-thyronine(out) + L-tryptophan(in) = 3,3',5-triiodo-L-thyronine(in) + L-tryptophan(out)

Direction not assertedBalancedTransportRhea 71411

3,3',5-triiodo-L-thyronine(out) + L-phenylalanine(in) = 3,3',5-triiodo-L-thyronine(in) + L-phenylalanine(out)

Direction not assertedBalancedTransportRhea 71415

3,3',5-triiodo-L-thyronine(out) + L-tyrosine(in) = 3,3',5-triiodo-L-thyronine(in) + L-tyrosine(out)

Direction not assertedBalancedTransportRhea 71419

an aromatic L-alpha-amino acid(in) + 3,3',5-triiodo-L-thyronine(out) = an aromatic L-alpha-amino acid(out) + 3,3',5-triiodo-L-thyronine(in)

Direction not assertedBalance undeterminableTransportRhea 71423

3,3'-diiodo-L-thyronine(out) + an aromatic L-alpha-amino acid(in) = 3,3'-diiodo-L-thyronine(in) + an aromatic L-alpha-amino acid(out)

Direction not assertedBalance undeterminableTransportRhea 71427

3,3',5'-triiodo-L-thyronine(out) + an aromatic L-alpha-amino acid(in) = 3,3',5'-triiodo-L-thyronine(in) + an aromatic L-alpha-amino acid(out)

Direction not assertedBalance undeterminableTransportRhea 71431

L-thyroxine(out) + an aromatic L-alpha-amino acid(in) = L-thyroxine(in) + an aromatic L-alpha-amino acid(out)

Direction not assertedBalance undeterminableTransportRhea 71435

L-dopa(out) + L-phenylalanine(in) = L-dopa(in) + L-phenylalanine(out)

Direction not assertedBalancedTransportRhea 71439

3-O-methyl-L-dopa(out) + L-phenylalanine(in) = 3-O-methyl-L-dopa(in) + L-phenylalanine(out)

Direction not assertedBalancedTransportRhea 71443

D-alanine(in) + Na(+)(in) = D-alanine(out) + Na(+)(out)

Direction not assertedBalancedTransportRhea 71447

bradykinin + H2O = L-Phe-L-Arg + bradykinin(1-7)

Left to rightBalancedRhea 71451

goralatide + H2O = N-acetyl-L-seryl-L-aspartate + L-lysyl-L-proline

Left to rightBalancedRhea 71455

substance P + H2O = substance P(1-9) + L-Leu-L-Met-NH2

Left to rightBalancedRhea 71459

substance P + H2O = substance P(1-8) + Gly-L-Leu-L-Met-NH2

Left to rightBalancedRhea 71463

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