Skip to content

Reference

Evidence

CompoundsSubstances with curated findings
OutcomesMeasured endpoints
ProteinsTransporters and enzymes
InteractionsPairs that share biology
PapersEvery paper a finding cites
ArticlesReadings of the evidence

Chemistry

ReactionsRhea and Human-GEM, by subsystem
ReachWhat a compound can become

Reference layer

PathwaysReactions grouped under one name
ProcessesWhat proteins are annotated as doing
AnatomyTissues, by what is expressed there
Cell typesCells, by what is expressed there
OrganismsSpecies a compound is prepared from
MaterialsSubstances that are not one molecule
AssessmentsRegulatory determinations, transcribed
DiseasesFeatures, genes, and where each sits

Atlas Graph Twin Access

Search the graph

Reference

Evidence

Compounds
Outcomes
Proteins
Interactions
Papers
Articles

Chemistry

Reactions
Reach

Reference layer

Pathways
Processes
Anatomy
Cell types
Organisms
Materials
Assessments
Diseases

Atlas Graph Twin Access

Loading the page.

Catalyst

Computational infrastructure for human biology, built on a provenance-aware knowledge graph. Findings retain their sources; research and simulation are the next layers.

The graph

Compounds
Outcomes
Proteins
Atlas
Interactions
Papers
Articles
Graph
Search

Reference layer

Pathways
Processes
Anatomy
Cell types
Organisms
Materials
Assessments
Diseases
Reactions
Reach

How it works

Mission
Method
Twin
How to read the evidence
Sources and licences

Build on it

Access
In your assistant
For agents
Query the graph
Bulk export

A reference for what the literature reports. Not medical advice.

© 2026 CatalystPrivacy TermsReference data under the licences listed on the attribution page.

Index

Reactions

Reactions from Rhea and Human-GEM · Reach

reactions in the graph: 31,435

By source

Rhea18,558
Human-GEM12,877

Inferred

Reference data, not a finding. Evidence key

Filter reactions by equationSource

Reactions

27,501–27,550 of 31,435, by identifier

L-glutamine(in) + L-alanine(out) + Na(+)(out) = L-glutamine(out) + L-alanine(in) + Na(+)(in)
Direction not assertedBalancedTransportRhea 70867
L-valine(out) + L-glutamine(in) + Na(+)(out) = L-valine(in) + L-glutamine(out) + Na(+)(in)
Direction not assertedBalancedTransportRhea 70871
L-glutamine(in) + L-methionine(out) + Na(+)(out) = L-glutamine(out) + L-methionine(in) + Na(+)(in)
Direction not assertedBalancedTransportRhea 70875
L-threonine(out) + L-glutamine(in) + Na(+)(out) = L-threonine(in) + L-glutamine(out) + Na(+)(in)
Direction not assertedBalancedTransportRhea 70879
L-glutamine(in) + L-glutamate(out) + Na(+)(out) + H(+)(out) = L-glutamine(out) + L-glutamate(in) + Na(+)(in) + H(+)(in)
Direction not assertedBalancedTransportRhea 70883
L-serine(out) + L-glutamine(in) + Na(+)(out) = L-serine(in) + L-glutamine(out) + Na(+)(in)
Direction not asserted

?

Balanced

Transport

Rhea 70887

L-asparagine(out) + L-glutamine(in) + Na(+)(out) = L-asparagine(in) + L-glutamine(out) + Na(+)(in)

Direction not assertedBalancedTransportRhea 70891

N-terminal L-cysteinyl-[protein] + O2 = N-terminal S-hydroxy-S-oxy-L-cysteinyl-[protein] + H(+)

Left to rightBalance undeterminableRhea 70895

(2R)-3-phospho-glyceroyl phosphate + alpha-D-ribose 1-phosphate = alpha-D-ribose 1,5-bisphosphate + (2R)-3-phosphoglycerate + H(+)

Left to rightBalancedRhea 70899

2-deoxy-alpha-D-ribose 1-phosphate + (2R)-3-phospho-glyceroyl phosphate = 2-deoxy-alpha-D-ribose 1,5-bisphosphate + (2R)-3-phosphoglycerate + H(+)

Left to rightBalancedRhea 70903

(2R)-3-phospho-glyceroyl phosphate + alpha-D-mannose 1-phosphate = alpha-D-mannose 1,6-bisphosphate + (2R)-3-phosphoglycerate + H(+)

Left to rightBalancedRhea 70907

alpha-D-glucose 6-phosphate + (2R)-3-phospho-glyceroyl phosphate = alpha-D-glucose 1,6-bisphosphate + (2R)-3-phosphoglycerate + H(+)

Left to rightBalancedRhea 70911

guanosine(in) + H(+)(in) = guanosine(out) + H(+)(out)

Direction not assertedBalancedTransportRhea 70915

dopamine(out) + chloride(out) + Na(+)(out) = dopamine(in) + chloride(in) + Na(+)(in)

Direction not assertedBalancedTransportRhea 70919

(R)-noradrenaline(out) + chloride(out) + Na(+)(out) = (R)-noradrenaline(in) + chloride(in) + Na(+)(in)

Direction not assertedBalancedTransportRhea 70923

(R)-glycerate(in) + H(+)(in) = (R)-glycerate(out) + H(+)(out)

Direction not assertedBalancedTransportRhea 70927

dopamine(out) + chloride(out) + 2 Na(+)(out) = dopamine(in) + chloride(in) + 2 Na(+)(in)

Direction not assertedBalancedTransportRhea 70931

L-lysine(in) = L-lysine(out)

Direction not assertedBalancedTransportRhea 70935

L-methionine(in) = L-methionine(out)

Direction not assertedBalancedTransportRhea 70939

L-isoleucine(in) = L-isoleucine(out)

Direction not assertedBalancedTransportRhea 70943

L-tryptophan(in) = L-tryptophan(out)

ReversibleBalancedTransportRhea 70947

D-serine + O2 + H2O = 3-hydroxypyruvate + H2O2 + NH4(+)

Left to rightBalancedRhea 70951

L-glutamate(in) + H(+)(in) = L-glutamate(out) + H(+)(out)

Direction not assertedBalancedTransportRhea 70955

D-tyrosine + O2 + H2O = 3-(4-hydroxyphenyl)pyruvate + H2O2 + NH4(+)

Direction not assertedBalancedRhea 70959

D-phenylalanine + O2 + H2O = 3-phenylpyruvate + H2O2 + NH4(+)

Left to rightBalancedRhea 70963

3-sulfino-L-alanine(out) + L-glutamate(in) + H(+)(in) = 3-sulfino-L-alanine(in) + L-glutamate(out) + H(+)(out)

Direction not assertedBalancedTransportRhea 70967

D-dopa + O2 + H2O = 3-(3,4-dihydroxyphenyl)pyruvate + H2O2 + NH4(+)

Left to rightBalancedRhea 70971

3-sulfino-L-alanine(out) + L-aspartate(in) = 3-sulfino-L-alanine(in) + L-aspartate(out)

Direction not assertedBalancedTransportRhea 70975

4-aminobutanoate(out) + n H(+)(in) = 4-aminobutanoate(in) + n H(+)(out)

Direction not assertedBalance undeterminableTransportRhea 70979

glycine(out) + n H(+)(in) = glycine(in) + n H(+)(out)

Direction not assertedBalance undeterminableTransportRhea 70983

beta-alanine(out) + n H(+)(in) = beta-alanine(in) + n H(+)(out)

Direction not assertedBalance undeterminableTransportRhea 70987

L-mannopyranose(in) + H(+)(in) = L-mannopyranose(out) + H(+)(out)

Direction not assertedBalancedTransportRhea 70991

L-cystine(out) + L-glutamate(in) = L-cystine(in) + L-glutamate(out)

Direction not assertedBalancedTransportRhea 70995

(S)-nicotine + reduced [NADPH--hemoprotein reductase] + O2 = (S)-nornicotine + formaldehyde + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Direction not assertedBalance undeterminableRhea 70999

L-histidine(in) + L-phenylalanine(out) = L-histidine(out) + L-phenylalanine(in)

Direction not assertedBalancedTransportRhea 71003

L-tryptophan(in) + L-phenylalanine(out) = L-tryptophan(out) + L-phenylalanine(in)

Direction not assertedBalancedTransportRhea 71007

L-isoleucine(in) + L-phenylalanine(out) = L-isoleucine(out) + L-phenylalanine(in)

Direction not assertedBalancedTransportRhea 71011

N-methylputrescine + O2 + H2O = 4-methylaminobutanal + H2O2 + NH4(+)

Direction not assertedBalancedRhea 71015

L-valine(in) + L-phenylalanine(out) = L-valine(out) + L-phenylalanine(in)

Direction not assertedBalancedTransportRhea 71019

L-leucine(in) + L-phenylalanine(out) = L-leucine(out) + L-phenylalanine(in)

Direction not assertedBalancedTransportRhea 71023

L-phenylalanine(out) + L-glutamine(in) = L-phenylalanine(in) + L-glutamine(out)

Direction not assertedBalancedTransportRhea 71027

L-cysteine(in) + L-phenylalanine(out) = L-cysteine(out) + L-phenylalanine(in)

Direction not assertedBalancedTransportRhea 71031

L-phenylalanine(out) + L-serine(in) = L-phenylalanine(in) + L-serine(out)

Direction not assertedBalancedTransportRhea 71035

L-phenylalanine(out) + L-methionine(in) = L-phenylalanine(in) + L-methionine(out)

Direction not assertedBalancedTransportRhea 71039

L-phenylalanine(out) + L-alanine(in) = L-phenylalanine(in) + L-alanine(out)

Direction not assertedBalancedTransportRhea 71043

L-phenylalanine(out) + glycine(in) = L-phenylalanine(in) + glycine(out)

Direction not assertedBalancedTransportRhea 71047

L-leucine(out) + L-methionine(in) = L-leucine(in) + L-methionine(out)

Direction not assertedBalancedTransportRhea 71051

L-cysteine(out) + L-methionine(in) = L-cysteine(in) + L-methionine(out)

Direction not assertedBalancedTransportRhea 71055

L-leucine(out) + L-arginine(in) = L-leucine(in) + L-arginine(out)

Left to rightBalancedTransportRhea 71059

L-histidine(out) + L-arginine(in) = L-histidine(in) + L-arginine(out)

Left to rightBalancedTransportRhea 71063

Page 551 of 629