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ReactionsRhea and Human-GEM, by subsystem
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Reference

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Computational infrastructure for human biology, built on a provenance-aware knowledge graph. Findings retain their sources; research and simulation are the next layers.

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A reference for what the literature reports. Not medical advice.

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Index

Reactions

Reactions from Rhea and Human-GEM · Reach

reactions in the graph: 31,435

By source

Rhea18,558
Human-GEM12,877

Inferred

Reference data, not a finding. Evidence key

Filter reactions by equationSource

Reactions

26,951–27,000 of 31,435, by identifier

7-oxocholesterol + NADPH + H(+) = 7beta-hydroxycholesterol + NADP(+)
Left to rightBalancedRhea 68656
17beta-estradiol 3-O-(beta-D-glucuronate) 17-sulfate + 3'-phosphoadenylyl sulfate = 17beta-estradiol 3-O-(3-sulfo-beta-D-glucuronate) 17-sulfate + adenosine 3',5'-bisphosphate + H(+)
Left to rightBalancedRhea 68660
17beta-estradiol 17-O-(beta-D-glucuronate) + 3'-phosphoadenylyl sulfate = 17beta-estradiol 17-O-(3-sulfo-beta-D-glucuronate) + adenosine 3',5'-bisphosphate + H(+)
Left to rightBalancedRhea 68664
16alpha,17beta-estriol 3-O-(beta-D-glucuronate) + 3'-phosphoadenylyl sulfate = 16alpha,17beta-estriol 3-O-(3-sulfo-beta-D-glucuronate) + adenosine 3',5'-bisphosphate + H(+)
Left to rightBalancedRhea 68668
16alpha,17beta-estriol 16-O-(beta-D-glucuronate) + 3'-phosphoadenylyl sulfate = 16alpha,17beta-estriol 16-O-(3-sulfo-beta-D-glucuronate) + adenosine 3',5'-bisphosphate + H(+)
Left to rightBalancedRhea 68672
estrone 3-O-(beta-D-glucuronate) + 3'-phosphoadenylyl sulfate = estrone 3-O-(3-sulfo-beta-D-glucuronate) + adenosine 3',5'-bisphosphate + H(+)

→ Left to right

Balanced

Rhea 68676

3alpha,20alpha-dihydroxy-5beta-pregnane 3-O-(beta-D-glucuronate) + 3'-phosphoadenylyl sulfate = 3alpha,20alpha-dihydroxy-5beta-pregnane 3-O-(3-sulfo-beta-D-glucuronate) + adenosine 3',5'-bisphosphate + H(+)

Left to rightBalancedRhea 68680

testosterone 17-O-(beta-D-glucuronate) + 3'-phosphoadenylyl sulfate = testosterone 17-O-(3-sulfo-beta-D-glucuronate) + adenosine 3',5'-bisphosphate + H(+)

Left to rightBalancedRhea 68684

3beta-androst-5-en-17-one 3-O-(beta-D-glucuronate) + 3'-phosphoadenylyl sulfate = 3beta-androst-5-en-17-one 3-O-(3-sulfo-beta-D-glucuronate) + adenosine 3',5'-bisphosphate + H(+)

Left to rightBalancedRhea 68688

3alpha,17alpha-dihydroxy-5beta-androstane-11-one-17beta-carboxylate 3-O-(beta-D-glucuronate) + 3'-phosphoadenylyl sulfate = 3alpha,17alpha-dihydroxy-5beta-androstane-11-one-17beta-carboxylate 3-O-(3-sulfo-beta-D-glucuronate) + adenosine 3',5'-bisphosphate + H(+)

Left to rightBalancedRhea 68692

17beta-estradiol 3-O-(beta-D-glucuronate) + 3'-phosphoadenylyl sulfate = 17beta-estradiol 3-O-(3-sulfo-beta-D-glucuronate) + adenosine 3',5'-bisphosphate + H(+)

Left to rightBalancedRhea 68696

16alpha,17beta-estriol 17-O-(beta-D-glucuronate) + 3'-phosphoadenylyl sulfate = 16alpha,17beta-estriol 17-O-(3-sulfo-beta-D-glucuronate) + adenosine 3',5'-bisphosphate + H(+)

Left to rightBalancedRhea 68700

3alpha-hydroxyetiocholan-17-one 3-O-(beta-D-glucuronate) + 3'-phosphoadenylyl sulfate = 3alpha-hydroxyetiocholan-17-one 3-O-(3-sulfo-beta-D-glucuronate) + adenosine 3',5'-bisphosphate + H(+)

Left to rightBalancedRhea 68704

(2E)-geranyl diphosphate + H2O = linalool + diphosphate

Direction not assertedBalancedRhea 68708

(2E,6E)-farnesyl diphosphate = (1S,2S,4R)-beta-elemene + diphosphate

Direction not assertedBalancedRhea 68712

(2E,6E)-farnesyl diphosphate = germacrene D + diphosphate

Direction not assertedBalancedRhea 68716

lanosterol + reduced [NADPH--hemoprotein reductase] + O2 = 26-hydroxylanosterol + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Direction not assertedBalance undeterminableRhea 68720

26-hydroxylanosterol + reduced [NADPH--hemoprotein reductase] + O2 = 26-oxolanosterol + oxidized [NADPH--hemoprotein reductase] + 2 H2O + H(+)

Direction not assertedBalance undeterminableRhea 68724

26-oxolanosterol + reduced [NADPH--hemoprotein reductase] + O2 = 3beta-hydroxy-lanosta-8, 24-dien-26-oate + oxidized [NADPH--hemoprotein reductase] + H2O + 2 H(+)

Direction not assertedBalance undeterminableRhea 68728

ganoderate DM + reduced [NADPH--hemoprotein reductase] + O2 = hainanate A + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Direction not assertedBalance undeterminableRhea 68732

ganoderate TR + reduced [NADPH--hemoprotein reductase] + O2 = ganoderate Jc + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Direction not assertedBalance undeterminableRhea 68736

7-oxocholesterol + NADPH + H(+) = 7alpha-hydroxycholesterol + NADP(+)

Direction not assertedBalancedRhea 68740

2 (R)-3-phenyllactate + 2 (R)-lactate + 4 L-leucine + 4 S-adenosyl-L-methionine + 8 ATP = PF1022A + 8 AMP + 4 S-adenosyl-L-homocysteine + 8 diphosphate + 8 H(+)

Direction not assertedBalancedRhea 68744

O-phospho-L-seryl-[protein] + alpha-D-glucose 1-phosphate = alpha-D-glucose 1,6-bisphosphate + L-seryl-[protein]

Direction not assertedBalance undeterminableRhea 68748

alpha-D-glucose 1,6-bisphosphate + L-seryl-[protein] = O-phospho-L-seryl-[protein] + alpha-D-glucose 6-phosphate

Direction not assertedBalance undeterminableRhea 68752

4 (R)-3-phenyllactate + 4 L-leucine + 4 S-adenosyl-L-methionine + 8 ATP = PF1022B + 8 AMP + 4 S-adenosyl-L-homocysteine + 8 diphosphate + 8 H(+)

Direction not assertedBalancedRhea 68756

3 (R)-3-phenyllactate + (R)-lactate + 4 L-leucine + 4 S-adenosyl-L-methionine + 8 ATP = PF1022C + 8 AMP + 4 S-adenosyl-L-homocysteine + 8 diphosphate + 8 H(+)

Direction not assertedBalancedRhea 68760

(R)-3-phenyllactate + 3 (R)-lactate + 4 L-leucine + 4 S-adenosyl-L-methionine + 8 ATP = PF1022D + 8 AMP + 4 S-adenosyl-L-homocysteine + 8 diphosphate + 8 H(+)

Direction not assertedBalancedRhea 68764

4 (R)-lactate + 4 L-leucine + 4 S-adenosyl-L-methionine + 8 ATP = PF1022F + 8 AMP + 4 S-adenosyl-L-homocysteine + 8 diphosphate + 8 H(+)

Direction not assertedBalancedRhea 68768

(2Z,6Z)-farnesyl diphosphate = germacrene C + diphosphate

Direction not assertedBalancedRhea 68772

(2Z,6Z)-farnesyl diphosphate = germacrene A + diphosphate

Direction not assertedBalancedRhea 68776

(2Z,6Z)-farnesyl diphosphate = alpha-humulene + diphosphate

Direction not assertedBalancedRhea 68780

(2Z,6Z)-farnesyl diphosphate = gamma-curcumene + diphosphate

Direction not assertedBalancedRhea 68784

(2Z,6Z)-farnesyl diphosphate = (Z)-gamma-bisabolene + diphosphate

Direction not assertedBalancedRhea 68788

alpha-NAD(+) + H2O = ADP-D-ribose + nicotinamide + H(+)

Direction not assertedBalancedRhea 68792

D-maltose + H2O = alpha-D-glucose + D-glucose

Left to rightBalancedRhea 68796

nigerose + H2O = alpha-D-glucose + D-glucose

Left to rightBalancedRhea 68800

kojibiose + H2O = alpha-D-glucose + D-glucose

Left to rightBalancedRhea 68804

6-O-alpha-D-glucopyranosyl-D-fructose + H2O = alpha-D-glucose + D-fructose

Left to rightBalancedRhea 68808

(2Z,6E)-farnesyl diphosphate = beta-bisabolene + diphosphate

Direction not assertedBalancedRhea 68812

(2Z,6E)-farnesyl diphosphate = (E)-alpha-bisabolene + diphosphate

Direction not assertedBalancedRhea 68816

(2Z,6E)-farnesyl diphosphate + H2O = (6E)-nerolidol + diphosphate

Direction not assertedBalancedRhea 68820

(2E)-geranyl diphosphate = (Z)-beta-ocimene + diphosphate

Direction not assertedBalancedRhea 68824

borneol + NAD(+) = camphor + NADH + H(+)

Direction not assertedBalancedRhea 68828

(2Z,6Z)-farnesyl diphosphate + H2O = (6Z)-nerolidol + diphosphate

Direction not assertedBalancedRhea 68832

(2Z,6E)-farnesyl diphosphate = (6R,7S)-himachala-9,11-diene + diphosphate

Direction not assertedBalancedRhea 68836

(2Z,6E)-farnesyl diphosphate = (6R,7S)-2,2,6-trimethyl-10-methylenebicyclo[5.4.0]undec-1(11)-ene + diphosphate

Direction not assertedBalancedRhea 68840

(2Z,6E)-farnesyl diphosphate = (Z)-alpha-bisabolene + diphosphate

Direction not assertedBalancedRhea 68844

(2Z,6E)-farnesyl diphosphate = gamma-cadinene + diphosphate

Direction not assertedBalancedRhea 68848

(2E,6E)-farnesyl diphosphate + H2O = (1S,6S,7R)-sesquipiperitol + diphosphate

Direction not assertedBalancedRhea 68852

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