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Reference

Evidence

CompoundsSubstances with curated findings
OutcomesMeasured endpoints
ProteinsTransporters and enzymes
InteractionsPairs that share biology
PapersEvery paper a finding cites
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Chemistry

ReactionsRhea and Human-GEM, by subsystem
ReachWhat a compound can become

Reference layer

PathwaysReactions grouped under one name
ProcessesWhat proteins are annotated as doing
AnatomyTissues, by what is expressed there
Cell typesCells, by what is expressed there
OrganismsSpecies a compound is prepared from
MaterialsSubstances that are not one molecule
AssessmentsRegulatory determinations, transcribed
DiseasesFeatures, genes, and where each sits

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Reference

Evidence

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Outcomes
Proteins
Interactions
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Articles

Chemistry

Reactions
Reach

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Processes
Anatomy
Cell types
Organisms
Materials
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Diseases

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Computational infrastructure for human biology, built on a provenance-aware knowledge graph. Findings retain their sources; research and simulation are the next layers.

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A reference for what the literature reports. Not medical advice.

© 2026 CatalystPrivacy TermsReference data under the licences listed on the attribution page.

Index

Reactions

Reactions from Rhea and Human-GEM · Reach

reactions in the graph: 31,435

By source

Rhea18,558
Human-GEM12,877

Inferred

Reference data, not a finding. Evidence key

Filter reactions by equationSource

Reactions

26,901–26,950 of 31,435, by identifier

(S)-3-hydroxyglutaryl-CoA = (2E)-glutaconyl-CoA + H2O
Right to leftBalancedRhea 68456
a phenolic steroid + 3'-phosphoadenylyl sulfate = a phenolic steroid 3-O-sulfate + adenosine 3',5'-bisphosphate + H(+)
Direction not assertedBalance undeterminableRhea 68460
2-butyloctyl sulfate + H2O = 2-butyloctan-1-ol + sulfate + H(+)
Direction not assertedBalancedRhea 68464
(2Z,6Z)-farnesyl diphosphate = (E)-gamma-bisabolene + diphosphate
Direction not assertedBalancedRhea 68468
(2Z,6Z)-farnesyl diphosphate = (E)-alpha-bisabolene + diphosphate
Direction not assertedBalancedRhea 68472
a (2R)-2-hydroperoxy fatty acid + H(+) = a fatty aldehyde + CO2 + H2O
Direction not assertedBalance undeterminableRhea 68476
(2R)-2-hydroperoxyhexadecanoate + H(+) = pentadecanal + CO2 + H2O

Direction not assertedBalancedRhea 68480

(2R)-2-hydroperoxydodecanoate + H(+) = undecanal + CO2 + H2O

Direction not assertedBalancedRhea 68484

(2R)-2-hydroperoxytetradecanoate + H(+) = tridecanal + CO2 + H2O

Direction not assertedBalancedRhea 68488

(2R,9Z,12Z)-2-hydroperoxyoctadecadienoate + H(+) = (8Z,11Z)-heptadecadienal + CO2 + H2O

Direction not assertedBalancedRhea 68492

(2R)-2-hydroperoxyoctadecanoate + H(+) = heptadecanal + CO2 + H2O

Direction not assertedBalancedRhea 68496

(2R,9Z)-2-hydroperoxyoctadecenoate + H(+) = (8Z)-heptadecenal + CO2 + H2O

Direction not assertedBalancedRhea 68500

(2Z,6Z)-farnesyl diphosphate = (Z)-beta-farnesene + diphosphate

Direction not assertedBalancedRhea 68504

(2E,6E)-farnesyl diphosphate = (Z)-beta-farnesene + diphosphate

Direction not assertedBalancedRhea 68508

(2Z,6Z)-farnesyl diphosphate = alpha-acoradiene + diphosphate

Direction not assertedBalancedRhea 68512

(2Z,6Z)-farnesyl diphosphate = beta-acoradiene + diphosphate

Direction not assertedBalancedRhea 68516

(2E,6E)-farnesyl diphosphate = beta-acoradiene + diphosphate

Direction not assertedBalancedRhea 68520

(2Z,6Z)-farnesyl diphosphate = beta-bisabolene + diphosphate

Direction not assertedBalancedRhea 68524

(2E,6E)-farnesyl diphosphate = beta-bisabolene + diphosphate

Direction not assertedBalancedRhea 68528

(2E,6E)-farnesyl diphosphate = (Z)-alpha-bisabolene + diphosphate

Direction not assertedBalancedRhea 68532

(2E,6E)-farnesyl diphosphate = (-)-alpha-cedrene + diphosphate

Direction not assertedBalancedRhea 68536

(2Z,6Z)-farnesyl diphosphate = (-)-alpha-cedrene + diphosphate

Direction not assertedBalancedRhea 68540

(2Z,6Z)-farnesyl diphosphate = (E)-beta-farnesene + diphosphate

Direction not assertedBalancedRhea 68544

psoralen + reduced [NADPH--hemoprotein reductase] + O2 = xanthotoxol + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Direction not assertedBalance undeterminableRhea 68548

UDP-N-acetyl-alpha-D-quinovosamine + NADP(+) = UDP-2-acetamido-2,6-dideoxy-alpha-D-xylo-hex-4-ulose + NADPH + H(+)

Direction not assertedBalancedRhea 68552

UDP-N-acetyl-alpha-D-quinovosamine + NAD(+) = UDP-2-acetamido-2,6-dideoxy-alpha-D-xylo-hex-4-ulose + NADH + H(+)

Direction not assertedBalancedRhea 68556

arsenate + D-glyceraldehyde 3-phosphate + NAD(+) = 1-arsono-3-phospho-D-glycerate + NADH + H(+)

Direction not assertedBalancedRhea 68560

6-methoxycoumarin + reduced [NADPH--hemoprotein reductase] + O2 = scopoletin + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Direction not assertedBalance undeterminableRhea 68564

N(5)-hydroxy-L-ornithine = (3S)-1,2-diazinane-3-carboxylate + H2O + H(+)

Direction not assertedBalancedRhea 68568

L-tyrosine(in) = L-tyrosine(out)

ReversibleBalancedTransportRhea 68572

xanthine(out) + ATP + H2O = xanthine(in) + ADP + phosphate + H(+)

Direction not assertedBalancedTransportRhea 68576

L-kynurenine(out) + ATP + H2O = L-kynurenine(in) + ADP + phosphate + H(+)

Direction not assertedBalancedTransportRhea 68580

L-tryptophan(out) + ATP + H2O = L-tryptophan(in) + ADP + phosphate + H(+)

Direction not assertedBalancedTransportRhea 68584

GDP-alpha-D-perosamine + (6R)-10-formyltetrahydrofolate = GDP-N-formyl-alpha-D-perosamine + (6S)-5,6,7,8-tetrahydrofolate + H(+)

Direction not assertedBalancedRhea 68588

(6S)-5,6,7,8-tetrahydrofolate(out) + ATP + H2O = (6S)-5,6,7,8-tetrahydrofolate(in) + ADP + phosphate + H(+)

Direction not assertedBalancedTransportRhea 68592

(2E,6E)-farnesyl diphosphate = beta-cadinene + diphosphate

Direction not assertedBalancedRhea 68596

(2S)-3-sulfopropanediol = 3-oxopropane-1-sulfonate + H2O

Direction not assertedBalancedRhea 68600

(2S)-3-sulfopropanediol = hydroxyacetone + sulfite + H(+)

Direction not assertedBalancedRhea 68604

isatin + NADPH + H(+) = 3-hydroxyindolin-2-one + NADP(+)

Left to rightBalancedRhea 68608

prostaglandin E1 + NADPH + H(+) = prostaglandin F1 + NADP(+)

Left to rightBalancedRhea 68612

cortisone + NADPH + H(+) = cortisol + NADP(+)

ReversibleBalancedRhea 68616

cortisone + NADPH + H(+) = 20beta-dihydrocortisone + NADP(+)

Direction not assertedBalancedRhea 68620

phycoerythrobilin-L-cysteinyl(82)-[C-phycoerythrin alpha-subunit] = apo-L-cysteinyl(82)-[C-phycoerythrin alpha-subunit] + (2R,3E)-phycoerythrobilin

Direction not assertedBalance undeterminableRhea 68624

phycoerythrobilin-L-cysteinyl(48)/L-cysteinyl(59)-[C-phycoerythrin beta-subunit] = apo-L-cysteinyl(48)/L-cysteinyl(59)-[C-phycoerythrin beta-subunit] + (2R,3E)-phycoerythrobilin

Direction not assertedBalance undeterminableRhea 68628

2 reduced [2Fe-2S]-[ferredoxin] + NAD(+) + 3 H(+)(in) = 2 oxidized [2Fe-2S]-[ferredoxin] + NADH + 2 H(+)(out)

Direction not assertedBalance undeterminableTransportRhea 68632

(2E)-geranyl diphosphate = sabinene + diphosphate

Direction not assertedBalancedRhea 68636

(2E)-geranyl diphosphate = limonene + diphosphate

Direction not assertedBalancedRhea 68640

(2E)-geranyl diphosphate = alpha-thujene + diphosphate

Direction not assertedBalancedRhea 68644

2 L-cysteine = L-lanthionine + hydrogen sulfide + H(+)

Direction not assertedBalancedRhea 68648

2 L-homocysteine = L-homolanthionine + hydrogen sulfide + H(+)

Direction not assertedBalancedRhea 68652

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