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CompoundsSubstances with curated findings
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ReactionsRhea and Human-GEM, by subsystem
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Reference

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Computational infrastructure for human biology, built on a provenance-aware knowledge graph. Findings retain their sources; research and simulation are the next layers.

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A reference for what the literature reports. Not medical advice.

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Index

Reactions

Reactions from Rhea and Human-GEM · Reach

reactions in the graph: 31,435

By source

Rhea18,558
Human-GEM12,877

Inferred

Reference data, not a finding. Evidence key

Filter reactions by equationSource

Reactions

24,151–24,200 of 31,435, by identifier

3 propionate 3-nitronate + 3 O2 + H2O = 3 3-oxopropanoate + 2 nitrate + nitrite + H2O2 + 3 H(+)
Direction not assertedBalancedRhea 57332
3-O-[beta-D-GlcA-(1->3)-beta-D-Xyl-(1->4)-Rib-ol-P-Rib-ol-P-3-beta-D-GalNAc-(1->3)-beta-D-GlcNAc-(1->4)-(O-6-P-alpha-D-Man)]-Thr-[protein] + UDP-alpha-D-xylose = 3-O-[alpha-D-Xyl-(1->3)-beta-D-GlcA-(1->4)-beta-D-Xyl-(1->4)-Rib-ol-P-Rib-ol-P-3-beta-D-GalNAc-(1->3)-beta-D-GlcNAc-(1->4)-(O-6-P-alpha-D-Man)]-Thr-[protein] + UDP + H(+)
Left to rightBalance undeterminableRhea 57336
3-hydroxy-L-kynurenine + S-adenosyl-L-methionine = 3-hydroxy-4-methyl-L-kynurenine + S-adenosyl-L-homocysteine + H(+)
Direction not assertedBalancedRhea 57340
3-hydroxy-D-kynurenine + S-adenosyl-L-methionine = 3-hydroxy-4-methyl-D-kynurenine + S-adenosyl-L-homocysteine + H(+)
Direction not assertedBalancedRhea 57344
3-hydroxy-4-methyl-L-kynurenine + H2O = 3-hydroxy-4-methylanthranilate + L-alanine + H(+)
Direction not assertedBalancedRhea 57348
zeinoxanthin + reduced [NADPH--hemoprotein reductase] + O2 = lutein + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Direction not assertedBalance undeterminableRhea 57352

hapalindole U + chloride + 2-oxoglutarate + O2 + H(+) = hapalindole G + succinate + CO2 + H2O

Direction not assertedBalancedRhea 57356

NADH + H2O = (6R)-NADHX

Direction not assertedBalancedRhea 57360

NADH + H2O = (6S)-NADHX

Direction not assertedBalancedRhea 57364

NADPH + H2O = (6R)-NADPHX

Direction not assertedBalancedRhea 57368

NADPH + H2O = (6S)-NADPHX

Direction not assertedBalancedRhea 57372

(S)-cis-N-methylcanadine + reduced [NADPH--hemoprotein reductase] + O2 = (S)-1-hydroxy-N-methylcanadine + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Direction not assertedBalance undeterminableRhea 57376

(S)-1-hydroxy-N-methylcanadine + reduced [NADPH--hemoprotein reductase] + O2 = (13S,14R)-1,13-dihydroxy-N-methylcanadine + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Direction not assertedBalance undeterminableRhea 57380

(13S,14R)-1,13-dihydroxy-N-methylcanadine + acetyl-CoA = (13S,14R)-13-O-acetyl-1-hydroxy-N-methylcanadine + CoA

Direction not assertedBalancedRhea 57384

(13S,14R)-13-O-acetyl-1-hydroxy-N-methylcanadine + reduced [NADPH--hemoprotein reductase] + O2 = (13S,14R)-13-O-acetyl-1,8-dihydroxy-N-methylcanadine + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Direction not assertedBalance undeterminableRhea 57388

(13S,14R)-13-O-acetyl-1,8-dihydroxy-N-methylcanadine = 3-O-acetyl-4'-O-demethylpapaveroxine + H(+)

Direction not assertedBalancedRhea 57392

3-O-acetyl-4'-O-demethylpapaveroxine + (S)-S-adenosyl-L-methionine = 3-O-acetylpapaveroxine + S-adenosyl-L-homocysteine + H(+)

Direction not assertedBalancedRhea 57396

3-O-acetylpapaveroxine + H2O = narcotine hemiacetal + acetate + H(+)

Direction not assertedBalancedRhea 57400

narcotine hemiacetal + NAD(+) = noscapine + NADH + H(+)

Direction not assertedBalancedRhea 57404

(2R)-3-(3,4-dihydroxyphenyl)lactate + NAD(+) = 3-(3,4-dihydroxyphenyl)pyruvate + NADH + H(+)

Direction not assertedBalancedRhea 57408

L-tyrosinal + AMP + diphosphate + NADP(+) = L-tyrosine + ATP + NADPH + H(+)

Direction not assertedBalancedRhea 57412

L-asparaginyl-[protein] + H2O = L-aspartyl-[protein] + NH4(+)

Left to rightBalance undeterminableRhea 57416

2 oxidized [cytochrome P450] + NADH = 2 reduced [cytochrome P450] + NAD(+) + H(+)

Direction not assertedBalance undeterminableRhea 57420

guaiacol + reduced [NADH--hemoprotein reductase] + O2 = oxidized [NADH--hemoprotein reductase] + catechol + formaldehyde + H2O + H(+)

Direction not assertedBalance undeterminableRhea 57424

anisole + reduced [NADH--hemoprotein reductase] + O2 = oxidized [NADH--hemoprotein reductase] + phenol + formaldehyde + H2O + H(+)

Direction not assertedBalance undeterminableRhea 57428

3-methoxycatechol + reduced [NADH--hemoprotein reductase] + O2 = 1,2,3-trihydroxybenzene + oxidized [NADH--hemoprotein reductase] + formaldehyde + H2O + H(+)

Direction not assertedBalance undeterminableRhea 57432

guaethol + reduced [NADH--hemoprotein reductase] + O2 = oxidized [NADH--hemoprotein reductase] + catechol + acetaldehyde + H2O + H(+)

Direction not assertedBalance undeterminableRhea 57436

2-methylanisole + reduced [NADH--hemoprotein reductase] + O2 = 2-hydroxytoluene + oxidized [NADH--hemoprotein reductase] + formaldehyde + H2O + H(+)

Direction not assertedBalance undeterminableRhea 57440

C-terminal L-alpha-aminoacyl-L-glutamyl-L-glutamyl-L-tyrosyl-[tubulin] + H2O = C-terminal L-alpha-aminoacyl-L-glutamyl-L-glutamyl-[tubulin] + L-tyrosine

Left to rightBalance undeterminableRhea 57444

D-tyrosine + tRNA(Tyr) + ATP = D-tyrosyl-tRNA(Tyr) + AMP + diphosphate + H(+)

Direction not assertedBalancedRhea 57448

L-glutaminyl-[protein] + S-adenosyl-L-methionine = N(5)-methyl-L-glutaminyl-[protein] + S-adenosyl-L-homocysteine + H(+)

Left to rightBalance undeterminableRhea 57452

(E)-sinapate + UDP-alpha-D-glucose = 4-O-(beta-D-glucosyl)-trans-sinapate + UDP + H(+)

Direction not assertedBalancedRhea 57456

(E)-sinapyl alcohol + UDP-alpha-D-glucose = 4-O-(beta-D-glucosyl)-trans-4-sinapoyl alcohol + UDP + H(+)

Direction not assertedBalancedRhea 57460

(E)-caffeate + UDP-alpha-D-glucose = 1-O-[(E)-caffeoyl]-beta-D-glucose + UDP

Direction not assertedBalancedRhea 57464

(E)-ferulate + UDP-alpha-D-glucose = 1-O-[(E)-feruloyl]-beta-D-glucose + UDP

Direction not assertedBalancedRhea 57468

(E)-4-coumarate + UDP-alpha-D-glucose = 1-O-[(E)-4-coumaroyl]-beta-D-glucose + UDP

Direction not assertedBalancedRhea 57472

dodecanoate + H2O2 = 2-hydroxydodecanoate + H2O

Direction not assertedBalancedRhea 57476

2-hydroxydodecanoate + H2O2 = 2,3-dihydroxydodecanoate + H2O

Direction not assertedBalancedRhea 57480

2 nitrite + AH2 + 2 H(+) = 2 nitric oxide + A + 2 H2O

Left to rightBalancedRhea 57488

propanoyl-CoA + oxaloacetate + H2O = 2-methylcitrate + CoA + H(+)

Direction not assertedBalancedRhea 57492

2-methylcitrate = 2-methyl-cis-aconitate + H2O

Direction not assertedBalancedRhea 57496

3-hydroxybutane-1,2,3-tricarboxylate = 2-methyl-cis-aconitate + H2O

Direction not assertedBalancedRhea 57500

3-hydroxybutane-1,2,3-tricarboxylate = pyruvate + succinate

Direction not assertedBalancedRhea 57504

staphylopine + NADP(+) + H2O = (2S)-2-amino-4-{[(1R)-1-carboxy-2-(1H-imidazol-4-yl)ethyl]amino}butanoate + pyruvate + NADPH + H(+)

Direction not assertedBalancedRhea 57508

chlorobenzene + NADH + O2 + H(+) = (1R,2R)-3-chlorocyclohexa-3,5-diene-1,2-diol + NAD(+)

Direction not assertedBalancedRhea 57512

dolabradiene + reduced [NADPH--hemoprotein reductase] + O2 = 15,16-epoxydolabrene + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Direction not assertedBalance undeterminableRhea 57516

15,16-epoxydolabrene + reduced [NADPH--hemoprotein reductase] + O2 = 3beta-hydroxy-15,16-epoxydolabrene + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Direction not assertedBalance undeterminableRhea 57520

a 5'-end triphospho-guanosine-ribonucleotide-tRNA(His) + H2O = a 5'-end phospho-guanosine-ribonucleotide-tRNA(His) + diphosphate + H(+)

Direction not assertedBalance undeterminableRhea 57524

a 5'-end ribonucleotide-RNA + a ribonucleoside 5'-triphosphate + ATP + H2O = a 5'-end phospho-ribonucleoside-ribonucleotide-RNA + AMP + 2 diphosphate + H(+)

Direction not assertedBalance undeterminableRhea 57528

a 5'-end ribonucleotide-RNA + ATP + H(+) = a 5'-end adenosine-5'-diphospho-5'-ribonucleotide-RNA + diphosphate

Direction not assertedBalance undeterminableRhea 57532

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