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ReactionsRhea and Human-GEM, by subsystem
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Reference

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Computational infrastructure for human biology, built on a provenance-aware knowledge graph. Findings retain their sources; research and simulation are the next layers.

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A reference for what the literature reports. Not medical advice.

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Index

Reactions

Reactions from Rhea and Human-GEM · Reach

reactions in the graph: 31,435

By source

Rhea18,558
Human-GEM12,877

Inferred

Reference data, not a finding. Evidence key

Filter reactions by equationSource

Reactions

23,901–23,950 of 31,435, by identifier

(2'-deoxyribonucleoside 5'-methylphosphotriester)-DNA + L-cysteinyl-[protein] = 2'-deoxyribonucleotide-DNA + S-methyl-L-cysteinyl-[protein] + H(+)
Direction not assertedBalance undeterminableRhea 56324
5'-triphosphoadenylyl-(2'->5')-adenylyl-(2'->5')-adenosine + H2O = 5'-triphosphoadenylyl-(2'->5')-adenosine + AMP + H(+)
Direction not assertedBalancedRhea 56328
5'-triphosphoadenylyl-(2'->5')-adenosine + H2O = AMP + ATP + H(+)
Direction not assertedBalancedRhea 56332
ent-isokaurene + 2 reduced [NADPH--hemoprotein reductase] + 2 O2 = ent-isokaurene-2beta,3beta-diol + 2 oxidized [NADPH--hemoprotein reductase] + 2 H2O + 2 H(+)
Direction not assertedBalance undeterminableRhea 56336
ent-isokauren-2beta-ol + reduced [NADPH--hemoprotein reductase] + O2 = ent-isokaurene-2beta,3beta-diol + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)
Direction not assertedBalance undeterminableRhea 56340
a 7-hydroxyisoflavone + UDP-alpha-D-glucose = a 7-hydroxyisoflavone 7-O-beta-D-glucoside + UDP + H(+)

? Direction not asserted

Balance undeterminable

Rhea 56344

2 bromide + 4-hydroxybenzoate + 2 NADPH + 2 O2 + 5 H(+) = 2,4-dibromophenol + CO2 + 2 NADP(+) + 4 H2O

Direction not assertedBalancedRhea 56348

bromide + 4-hydroxybenzoate + NADPH + O2 + 2 H(+) = 3-bromo-4-hydroxybenzoate + NADP(+) + 2 H2O

Direction not assertedBalancedRhea 56352

3-bromo-4-hydroxybenzoate + bromide + NADPH + O2 + 3 H(+) = 2,4-dibromophenol + CO2 + NADP(+) + 2 H2O

Direction not assertedBalancedRhea 56356

13-deoxycarminomycin + NADPH + O2 + H(+) = 13-dihydrocarminomycin + NADP(+) + H2O

Direction not assertedBalancedRhea 56360

13-dihydrocarminomycin + NADPH + O2 + H(+) = carminomycin + NADP(+) + 2 H2O

Direction not assertedBalancedRhea 56364

3,4-dihydroxybenzoate + 2 bromide + 2 NADPH + 2 O2 + 5 H(+) = 3,5-dibromobenzene-1,2-diol + CO2 + 2 NADP(+) + 4 H2O

Direction not assertedBalancedRhea 56368

3,4-dihydroxybenzoate + bromide + NADPH + O2 + 2 H(+) = 3-bromo-4,5-dihydroxybenzoate + NADP(+) + 2 H2O

Direction not assertedBalancedRhea 56372

3-bromo-4,5-dihydroxybenzoate + bromide + NADPH + O2 + 3 H(+) = 3,5-dibromobenzene-1,2-diol + CO2 + NADP(+) + 2 H2O

Direction not assertedBalancedRhea 56376

(1H-pyrrole-2-carbonyl)-[peptidyl-carrier protein] + 2 FADH2 + 2 chloride + 2 O2 = (4,5-dichloro-1H-pyrrole-2-carbonyl)-[peptidyl-carrier protein] + 2 FAD + 4 H2O

Direction not assertedBalance undeterminableRhea 56380

(1H-pyrrole-2-carbonyl)-[peptidyl-carrier protein] + FADH2 + chloride + O2 = (5-chloro-1H-pyrrole-2-carbonyl)-[peptidyl-carrier protein] + FAD + 2 H2O

Direction not assertedBalance undeterminableRhea 56384

(5-chloro-1H-pyrrole-2-carbonyl)-[peptidyl-carrier protein] + FADH2 + chloride + O2 = (4,5-dichloro-1H-pyrrole-2-carbonyl)-[peptidyl-carrier protein] + FAD + 2 H2O

Direction not assertedBalance undeterminableRhea 56388

[(3R)-hydroxybutanoate](n) + H2O = [(3R)-hydroxybutanoate](n-2) + (3R)-hydroxybutanoate dimer + H(+)

Direction not assertedBalance undeterminableRhea 56392

[(3R)-hydroxybutanoate](n) + H2O = [(3R)-hydroxybutanoate](n-3) + (3R)-hydroxybutanoate trimer + H(+)

Direction not assertedBalance undeterminableRhea 56396

[(3R)-hydroxybutanoate](n) + H2O = [(3R)-hydroxybutanoate](n-4) + (3R)-hydroxybutanoate tetramer + H(+)

Direction not assertedBalance undeterminableRhea 56400

[(3R)-hydroxybutanoate](n) + H2O = [(3R)-hydroxybutanoate](n-5) + (3R)-hydroxybutanoate pentamer + H(+)

Direction not assertedBalance undeterminableRhea 56404

(9Z,12Z,15Z)-octadecatrienoyl-CoA + 1-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine = 1-(9Z-octadecaenoyl)-2-(9Z,12Z,15Z-octadecatrienoyl)-sn-glycero-3-phosphocholine + CoA

Direction not assertedBalancedRhea 56408

1,2-ditetradecanoyl-sn-glycero-3-phosphocholine + 1,2-di-(9Z-octadecenoyl)-sn-glycerol = 1,2-ditetradecanoyl-sn-glycerol + 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine

Direction not assertedBalancedRhea 56412

2-O-(alpha-D-glucopyranosyl)glycerol + phosphate = alpha-D-glucose 1-phosphate + glycerol

Direction not assertedBalancedRhea 56416

apo-[D-alanyl-carrier protein] + CoA = holo-[D-alanyl-carrier protein] + adenosine 3',5'-bisphosphate + H(+)

Direction not assertedBalance undeterminableRhea 56420

N,1-dihexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphoethanolamine + H2O = N,1-dihexadecanoyl-sn-glycero-3-phosphoethanolamine + (9Z,12Z)-octadecadienoate + H(+)

Left to rightBalancedRhea 56424

1,2-di-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphocholine + H2O = 1-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phosphocholine + (9Z,12Z)-octadecadienoate + H(+)

Left to rightBalancedRhea 56428

1-hexadecanoyl-2-octadecanoyl-sn-glycero-3-phosphocholine + H2O = octadecanoate + 1-hexadecanoyl-sn-glycero-3-phosphocholine + H(+)

Left to rightBalancedRhea 56432

1-hexadecanoyl-2-octadecanoyl-sn-glycero-3-phosphocholine + H2O = 2-octadecanoyl-sn-glycero-3-phosphocholine + hexadecanoate + H(+)

Left to rightBalancedRhea 56436

1-octadecanoyl-2-hexadecanoyl-sn-glycero-3-phosphocholine + H2O = 1-octadecanoyl-sn-glycero-3-phosphocholine + hexadecanoate + H(+)

Left to rightBalancedRhea 56440

1-octadecanoyl-2-hexadecanoyl-sn-glycero-3-phosphocholine + H2O = 2-hexadecanoyl-sn-glycero-3-phosphocholine + octadecanoate + H(+)

Left to rightBalancedRhea 56444

1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + H2O = 2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + (9Z)-octadecenoate + H(+)

Left to rightBalancedRhea 56448

3-geranyl-3-[(Z)-2-isocyanoethenyl]-1H-indole = 12-epi-hapalindole U

Direction not assertedBalancedRhea 56452

3-geranyl-3-[(Z)-2-isocyanoethenyl]-1H-indole = 12-epi-fischerindole U

Direction not assertedBalancedRhea 56456

N,1-di-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + H2O = N-(9Z-octadecenoyl) ethanolamine + 1-(9Z-octadecenoyl)-sn-glycero-3-phosphate + H(+)

Left to rightBalancedRhea 56460

1-O-(1Z-octadecenoyl)-2-(9Z-octadecenoyl)-sn-glycero-3-phospho-N-hexadecanoyl-ethanolamine + H2O = 1-O-(1Z-octadecenoyl)-2-(9Z-octadecenoyl)-sn-glycero-3-phosphate + N-hexadecanoylethanolamine + H(+)

Left to rightBalancedRhea 56464

(1H-pyrrole-2-carbonyl)-[peptidyl-carrier protein] + 3 bromide + 3 FADH2 + 3 O2 = (3,4,5-tribromo-1H-pyrrole-2-carbonyl)-[peptidyl-carrier protein] + 3 FAD + 6 H2O

Direction not assertedBalance undeterminableRhea 56468

(1H-pyrrole-2-carbonyl)-[peptidyl-carrier protein] + bromide + FADH2 + O2 = (5-bromo-1H-pyrrole-2-carbonyl)-[peptidyl-carrier protein] + FAD + 2 H2O

Direction not assertedBalance undeterminableRhea 56472

(5-bromo-1H-pyrrole-2-carbonyl)-[peptidyl-carrier protein] + bromide + FADH2 + O2 = (4,5-dibromo-1H-pyrrole-2-carbonyl)-[peptidyl-carrier protein] + FAD + 2 H2O

Direction not assertedBalance undeterminableRhea 56476

(4,5-dibromo-1H-pyrrole-2-carbonyl)-[peptidyl-carrier protein] + bromide + FADH2 + O2 = (3,4,5-tribromo-1H-pyrrole-2-carbonyl)-[peptidyl-carrier protein] + FAD + 2 H2O

Direction not assertedBalance undeterminableRhea 56480

oleanolate + 3 reduced [NADPH--hemoprotein reductase] + 3 O2 = gypsogenate + 3 oxidized [NADPH--hemoprotein reductase] + 4 H2O + 4 H(+)

Direction not assertedBalance undeterminableRhea 56484

oleanolate + reduced [NADPH--hemoprotein reductase] + O2 = hederagenin + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Direction not assertedBalance undeterminableRhea 56488

hederagenin + reduced [NADPH--hemoprotein reductase] + O2 = gypsogenin + oxidized [NADPH--hemoprotein reductase] + 2 H2O + H(+)

Direction not assertedBalance undeterminableRhea 56492

gypsogenin + reduced [NADPH--hemoprotein reductase] + O2 = gypsogenate + oxidized [NADPH--hemoprotein reductase] + H2O + 2 H(+)

Direction not assertedBalance undeterminableRhea 56496

(R)-3,5-bisphosphomevalonate + H(+) = isopentenyl phosphate + CO2 + phosphate

Direction not assertedBalancedRhea 56500

1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine = N,1,2-tri-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + 1-hexadecanoyl-sn-glycero-3-phosphocholine + H(+)

Left to rightBalancedRhea 56504

3-O-(beta-D-galactosyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-2-O-phosphoxylosyl)-L-seryl-[protein] + UDP-alpha-D-glucuronate = 3-O-[beta-D-GlcA-(1->3)-beta-D-Gal-(1->3)-beta-D-Gal-(1->4)-beta-D-2-O-P-Xyl]-L-seryl-[protein] + UDP + H(+)

Direction not assertedBalance undeterminableRhea 56508

3-O-[beta-D-GlcA-(1->3)-beta-D-Gal-(1->3)-beta-D-Gal-(1->4)-beta-D-2-O-P-Xyl]-L-seryl-[protein] + H2O = 3-O-(beta-D-GlcA-(1->3)-beta-D-Gal-(1->3)-beta-D-Gal-(1->4)-beta-D-Xyl)-L-seryl-[protein] + phosphate

Direction not assertedBalance undeterminableRhea 56512

Fe-coproporphyrin III + 2 H2O2 + 2 H(+) = heme b + 2 CO2 + 4 H2O

Direction not assertedBalancedRhea 56516

Fe-coproporphyrin III + 2 S-adenosyl-L-methionine = heme b + 2 5'-deoxyadenosine + 2 L-methionine + 2 CO2

Direction not assertedBalancedRhea 56520

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