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ReactionsRhea and Human-GEM, by subsystem
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Reference

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Computational infrastructure for human biology, built on a provenance-aware knowledge graph. Findings retain their sources; research and simulation are the next layers.

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A reference for what the literature reports. Not medical advice.

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Index

Reactions

Reactions from Rhea and Human-GEM · Reach

reactions in the graph: 31,435

By source

Rhea18,558
Human-GEM12,877

Inferred

Reference data, not a finding. Evidence key

Filter reactions by equationSource

Reactions

23,851–23,900 of 31,435, by identifier

2-all-trans-heptaprenylphenol + NADPH + O2 + H(+) = 3-(all-trans-heptaprenyl)benzene-1,2-diol + NADP(+) + H2O
Direction not assertedBalancedRhea 56120
all-trans-lycopene + dimethylallyl diphosphate + A + H2O = nonaflavuxanthin + AH2 + diphosphate
Direction not assertedBalancedRhea 56124
nonaflavuxanthin + dimethylallyl diphosphate + A + H2O = flavuxanthin + AH2 + diphosphate
Direction not assertedBalancedRhea 56128
(5R)-5,6-dihydro-5-(thymidin-7-yl)thymidine in DNA = a thymidine dimer in DNA
Direction not assertedBalance undeterminableRhea 56132
2 a phenolic donor + H2O2 = 2 a phenolic radical donor + 2 H2O
Left to rightBalance undeterminableRhea 56136
nitrate + a quinol = a quinone + nitrite + H2O
Direction not assertedBalance undeterminableRhea 56144
sn-glycerol 3-phosphocholine + hexadecanoyl-CoA = hexadecanoyl-sn-glycero-3-phosphocholine + CoA

Direction not assertedBalancedRhea 56148

(9Z,12Z)-octadecadienoyl-CoA + sn-glycerol 3-phosphocholine = (9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphocholine + CoA

Direction not assertedBalancedRhea 56152

(12R)-hydroxy-(9Z)-octadecenoyl-CoA + sn-glycerol 3-phosphocholine = (12R-hydroxy-9Z-octadecenoyl)-sn-glycero-3-phosphocholine + CoA

Direction not assertedBalancedRhea 56156

an archaeal dolichyl alpha-D-glucosyl phosphate + UDP-alpha-D-glucuronate = an archaeal dolichyl beta-D-glucuronosyl-(1->4)-alpha-D-glucosyl phosphate + UDP + H(+)

Direction not assertedBalance undeterminableRhea 56160

(9Z,12Z,15Z)-octadecatrienoyl-CoA + sn-glycerol 3-phosphocholine = (9Z,12Z,15Z-octadecatrienoyl)-sn-glycero-3-phosphocholine + CoA

Direction not assertedBalancedRhea 56164

sn-glycerol 3-phosphocholine + (9Z)-octadecenoyl-CoA = (9Z-octadecenoyl)-sn-glycero-3-phosphocholine + CoA

Direction not assertedBalancedRhea 56168

FMN + O2 = 8-demethyl-8-formylriboflavin 5'-phosphate + H2O

Direction not assertedBalancedRhea 56172

8-demethyl-8-formylriboflavin 5'-phosphate + A + H2O = 8-carboxy-8-demethylriboflavin 5'-phosphate + AH2 + H(+)

Direction not assertedBalancedRhea 56176

8-carboxy-8-demethylriboflavin 5'-phosphate + L-glutamate + 2 A + H2O = 8-amino-8-demethylriboflavin 5'-phosphate + 2-oxoglutarate + 2 AH2 + CO2

Direction not assertedBalancedRhea 56180

a globoside Gb4Cer + UDP-alpha-D-galactose = a globoside NOR1 + UDP + H(+)

Left to rightBalance undeterminableRhea 56184

3-O-[N-acetyl-beta-D-glucosaminyl-(1->3)-N-acetyl-alpha-D-galactosaminyl]-L-seryl-[protein] + UDP-N-acetyl-alpha-D-glucosamine = 3-O-[N-acetyl-beta-D-glucosaminyl-(1->3)-[N-acetyl-beta-D-glucosaminyl-(1->6)]-N-acetyl-alpha-D-galactosaminyl]-L-seryl-[protein] + UDP + H(+)

Direction not assertedBalance undeterminableRhea 56188

a 3-O-[N-acetyl-beta-D-glucosaminyl-(1->3)-N-acetyl-alpha-D-galactosaminyl]-L-threonyl-[protein] + UDP-N-acetyl-alpha-D-glucosamine = 3-O-[N-acetyl-beta-D-glucosaminyl-(1->3)-[N-acetyl-beta-D-glucosaminyl-(1->6)]-N-acetyl-alpha-D-galactosaminyl]-L-threonyl-[protein] + UDP + H(+)

Direction not assertedBalance undeterminableRhea 56192

a 3-O-[N-acetyl-alpha-D-galactosaminyl]-L-threonyl-[protein] + UDP-alpha-D-galactose = a 3-O-[beta-D-galactosyl-(1->3)-N-acetyl-alpha-D-galactosaminyl]-L-threonyl-[protein] + UDP + H(+)

Left to rightBalance undeterminableRhea 56196

a 3-O-[N-acetyl-alpha-D-galactosaminyl]-L-seryl-[protein] + UDP-alpha-D-galactose = a 3-O-[beta-D-galactosyl-(1->3)-N-acetyl-alpha-D-galactosaminyl]-L-seryl-[protein] + UDP + H(+)

Left to rightBalance undeterminableRhea 56200

a 3-O-[beta-D-galactosyl-(1->3)-N-acetyl-alpha-D-galactosaminyl]-L-seryl-[protein] + CMP-N-acetyl-beta-neuraminate = a 3-O-[N-acetyl-alpha-neuraminyl-(2->3)-beta-D-galactosyl-(1->3)-N-acetyl-alpha-D-galactosaminyl]-L-seryl-[protein] + CMP + H(+)

Left to rightBalance undeterminableRhea 56204

a 3-O-[beta-D-galactosyl-(1->3)-N-acetyl-alpha-D-galactosaminyl]-L-threonyl-[protein] + CMP-N-acetyl-beta-neuraminate = a 3-O-[N-acetyl-alpha-neuraminyl-(2->3)-beta-D-galactosyl-(1->3)-N-acetyl-alpha-D-galactosaminyl]-L-threonyl-[protein] + CMP + H(+)

Left to rightBalance undeterminableRhea 56208

a 3-O-[beta-D-galactosyl-(1->3)-N-acetyl-alpha-D-galactosaminyl]-L-seryl-[protein] + UDP-N-acetyl-alpha-D-glucosamine = 3-O-{beta-D-galactosyl-(1->3)-[N-acetyl-beta-D-glucosaminyl-(1->6)]-N-acetyl-alpha-D-galactosaminyl}-L-seryl-[protein] + UDP + H(+)

Left to rightBalance undeterminableRhea 56212

a 3-O-[beta-D-galactosyl-(1->3)-N-acetyl-alpha-D-galactosaminyl]-L-threonyl-[protein] + UDP-N-acetyl-alpha-D-glucosamine = a 3-O-{beta-D-galactosyl-(1->3)-[N-acetyl-beta-D-glucosaminyl-(1->6)]-N-acetyl-alpha-D-galactosaminyl}-L-threonyl-[protein] + UDP + H(+)

Left to rightBalance undeterminableRhea 56216

3-O-{beta-D-galactosyl-(1->3)-[N-acetyl-beta-D-glucosaminyl-(1->6)]-N-acetyl-alpha-D-galactosaminyl}-L-seryl-[protein] + UDP-N-acetyl-alpha-D-glucosamine = 3-O-{beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->3)-[beta-D-GlcNAc-(1->6)]-alpha-D-GalNAc}-L-seryl-[protein] + UDP + H(+)

Direction not assertedBalance undeterminableRhea 56220

a 3-O-{beta-D-galactosyl-(1->3)-[N-acetyl-beta-D-glucosaminyl-(1->6)]-N-acetyl-alpha-D-galactosaminyl}-L-threonyl-[protein] + UDP-N-acetyl-alpha-D-glucosamine = 3-O-{beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->3)-[beta-D-GlcNAc-(1->6)]-alpha-D-GalNAc}-L-threonyl-[protein] + UDP + H(+)

Direction not assertedBalance undeterminableRhea 56224

(9Z)-hexadecenoyl-CoA + sn-glycerol 3-phosphocholine = (9Z-hexadecenoyl)-sn-glycero-3-phosphocholine + CoA

Direction not assertedBalancedRhea 56228

[(1->4)-alpha-D-galacturonosyl](n) + H2O = alpha-D-galacturonosyl-(1->4)-D-galacturonate + [(1->4)-alpha-D-galacturonosyl](n-2)

Direction not assertedBalance undeterminableRhea 56232

1-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + sn-glycerol 3-phosphocholine = (9Z-octadecenoyl)-sn-glycero-3-phosphocholine + sn-glycero-3-phosphoethanolamine

Direction not assertedBalancedRhea 56236

1,2-dioctanoyl-sn-glycero-3-phosphocholine + all-trans-retinol--[retinol-binding protein] = 2-octanoyl-sn-glycero-3-phosphocholine + all-trans-retinyl octanoate + apo--[retinol-binding protein]

Left to rightBalance undeterminableRhea 56240

all-trans-retinol--[retinol-binding protein] + 1,2-dihexadecanoyl-sn-glycero-3-phosphocholine = apo--[retinol-binding protein] + all-trans-retinyl hexadecanoate + 2-hexadecanoyl-sn-glycero-3-phosphocholine

Left to rightBalance undeterminableRhea 56244

1,2-didodecanoyl-sn-glycero-3-phosphocholine + all-trans-retinol--[retinol-binding protein] = 2-dodecanoyl-sn-glycero-3-phosphocholine + all-trans-retinyl dodecanoate + apo--[retinol-binding protein]

Left to rightBalance undeterminableRhea 56248

3-O-[N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl]-L-seryl-[protein] + UDP-N-acetyl-alpha-D-glucosamine = O(3)-{N-acetyl-beta-D-glucosaminyl-(1->2)-[N-acetyl-beta-D-glucosaminyl-(1->6)]-alpha-D-mannosyl}-L-seryl-[protein] + UDP + H(+)

Direction not assertedBalance undeterminableRhea 56252

3-O-[N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl]-L-threonyl-[protein] + UDP-N-acetyl-alpha-D-glucosamine = O(3)-{N-acetyl-beta-D-glucosaminyl-(1->2)-[N-acetyl-beta-D-glucosaminyl-(1->6)]-alpha-D-mannosyl}-L-threonyl-[protein] + UDP + H(+)

Direction not assertedBalance undeterminableRhea 56256

N(4)-{beta-D-GlcNAc-(1->2)-[beta-D-GlcNAc-(1->4)]-alpha-D-Man-(1->3)-[beta-D-GlcNAc-(1->2)-[beta-D-GlcNAc-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc}-L-asparaginyl-[protein] + 4 UDP-alpha-D-galactose = N(4)-{beta-D-Gal-(1->4)-beta-D-GlcNAc-(1->2)-[beta-D-Gal-(1->4)-beta-D-GlcNAc-(1->4)]-alpha-D-Man-(1->3)-[beta-D-Gal-(1->4)-beta-D-GlcNAc-(1->2)-[beta-D-Gal-(1->4)-beta-D-GlcNAc-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc}-L-asparaginyl-[protein] + 4 UDP + 4 H(+)

Direction not assertedBalance undeterminableRhea 56260

N(4)-{beta-D-Gal-(1->4)-beta-D-GlcNAc-(1->2)-[beta-D-Gal-(1->4)-beta-D-GlcNAc-(1->4)]-alpha-D-Man-(1->3)-[beta-D-Gal-(1->4)-beta-D-GlcNAc-(1->2)-[beta-D-Gal-(1->4)-beta-D-GlcNAc-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc}-L-asparaginyl-[protein] + CMP-N-acetyl-beta-neuraminate = N(4)-{beta-D-Gal-(1->4)-beta-D-GlcNAc-(1->2)-[beta-D-Gal-(1->4)-beta-D-GlcNAc-(1->4)]-alpha-D-Man-(1->3)-[alpha-Neu5Ac-(2->3)-beta-D-Gal-(1->4)-beta-D-GlcNAc-(1->2)-[beta-D-Gal-(1->4)-beta-D-GlcNAc-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc}-L-asparaginyl-[protein] + CMP + H(+)

Direction not assertedBalance undeterminableRhea 56264

N(4)-{beta-D-Gal-(1->4)-beta-D-GlcNAc-(1->2)-[beta-D-Gal-(1->4)-beta-D-GlcNAc-(1->4)]-alpha-D-Man-(1->3)-[alpha-Neu5Ac-(2->3)-beta-D-Gal-(1->4)-beta-D-GlcNAc-(1->2)-[beta-D-Gal-(1->4)-beta-D-GlcNAc-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc}-L-asparaginyl-[protein] + CMP-N-acetyl-beta-neuraminate = N(4)-{alpha-Neu5Ac-(2->6)-beta-D-Gal-(1->4)-beta-D-GlcNAc-(1->2)-[beta-D-Gal-(1->4)-beta-D-GlcNAc-(1->4)]-alpha-D-Man-(1->3)-[alpha-Neu5Ac-(2->3)-beta-D-Gal-(1->4)-beta-D-GlcNAc-(1->2)-[beta-D-Gal-(1->4)-beta-D-GlcNAc-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc}-L-asparaginyl-[protein] + CMP + H(+)

Direction not assertedBalance undeterminableRhea 56268

4 Fe(III)-[cytochrome cL] + methanol + H2O = 4 Fe(II)-[cytochrome cL] + formate + 5 H(+)

Direction not assertedBalance undeterminableRhea 56272

L-proline + ATP = 3'-L-prolyl-AMP + diphosphate

Direction not assertedBalancedRhea 56276

3'-L-prolyl-AMP + holo-[peptidyl-carrier protein] = L-prolyl-[peptidyl-carrier protein] + AMP

Direction not assertedBalance undeterminableRhea 56280

a (3R,4R)-4,2'-dihydroxyisoflavan + NADP(+) = a (3R)-2'-hydroxyisoflavanone + NADPH + H(+)

Direction not assertedBalance undeterminableRhea 56284

albendazole + reduced [NADPH--hemoprotein reductase] + O2 = hydroxyalbendazole + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Left to rightBalance undeterminableRhea 56288

fenbendazole + reduced [NADPH--hemoprotein reductase] + O2 = 4'-hydroxyfenbendazole + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Direction not assertedBalance undeterminableRhea 56292

2-oxo-3-sulfanylpropanoate + L-cysteinyl-[protein] = S-sulfanyl-L-cysteinyl-[protein] + pyruvate

Direction not assertedBalance undeterminableRhea 56296

S-sulfanyl-L-cysteinyl-[protein] + [thioredoxin]-dithiol = [thioredoxin]-disulfide + L-cysteinyl-[protein] + hydrogen sulfide + H(+)

Direction not assertedBalance undeterminableRhea 56300

rifampicin + ATP + H2O = 21-phosphorifampicin + AMP + phosphate + 2 H(+)

Direction not assertedBalancedRhea 56304

(S)-reticuline + reduced [NADPH--hemoprotein reductase] + O2 = 1,2-dehydroreticuline + oxidized [NADPH--hemoprotein reductase] + 2 H2O + H(+)

Direction not assertedBalance undeterminableRhea 56308

3,5-bis(diphospho)-1D-myo-inositol 1,2,4,6-tetrakisphosphate + H2O = 3-diphospho-1D-myo-inositol 1,2,4,5,6-pentakisphosphate + phosphate + 2 H(+)

Left to rightBalancedRhea 56312

3-amino-4-hydroxybenzoate + acetyl-CoA = 3-acetylamino-4-hydroxybenzoate + CoA

Direction not assertedBalancedRhea 56316

a 5-hydroxy anthocyanidin + UDP-alpha-D-glucose = an anthocyanin 5-O-beta-D-glucoside + UDP + H(+)

Direction not assertedBalance undeterminableRhea 56320

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