Skip to content

Reference

Evidence

CompoundsSubstances with curated findings
OutcomesMeasured endpoints
ProteinsTransporters and enzymes
InteractionsPairs that share biology
PapersEvery paper a finding cites
ArticlesReadings of the evidence

Chemistry

ReactionsRhea and Human-GEM, by subsystem
ReachWhat a compound can become

Reference layer

PathwaysReactions grouped under one name
ProcessesWhat proteins are annotated as doing
AnatomyTissues, by what is expressed there
Cell typesCells, by what is expressed there
OrganismsSpecies a compound is prepared from
MaterialsSubstances that are not one molecule
AssessmentsRegulatory determinations, transcribed
DiseasesFeatures, genes, and where each sits

Atlas Graph Twin Access

Search the graph

Reference

Evidence

Compounds
Outcomes
Proteins
Interactions
Papers
Articles

Chemistry

Reactions
Reach

Reference layer

Pathways
Processes
Anatomy
Cell types
Organisms
Materials
Assessments
Diseases

Atlas Graph Twin Access

Loading the page.

Catalyst

Computational infrastructure for human biology, built on a provenance-aware knowledge graph. Findings retain their sources; research and simulation are the next layers.

The graph

Compounds
Outcomes
Proteins
Atlas
Interactions
Papers
Articles
Graph
Search

Reference layer

Pathways
Processes
Anatomy
Cell types
Organisms
Materials
Assessments
Diseases
Reactions
Reach

How it works

Mission
Method
Twin
How to read the evidence
Sources and licences

Build on it

Access
In your assistant
For agents
Query the graph
Bulk export

A reference for what the literature reports. Not medical advice.

© 2026 CatalystPrivacy TermsReference data under the licences listed on the attribution page.

Index

Reactions

Reactions from Rhea and Human-GEM · Reach

reactions in the graph: 31,435

By source

Rhea18,558
Human-GEM12,877

Inferred

Reference data, not a finding. Evidence key

Filter reactions by equationSource

Reactions

23,951–24,000 of 31,435, by identifier

dihydro-heme d1 + A = heme d1 + AH2
Direction not assertedBalancedRhea 56524
D-tryptophan + FADH2 + chloride + O2 = 6-chloro-D-tryptophan + FAD + 2 H2O
Direction not assertedBalancedRhea 56528
N-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-ethanolamine phosphate + H2O = N-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-ethanolamine + phosphate
Left to rightBalancedRhea 56532
1,2-di-(12R-hydroxy-9Z-octadecenoyl)-sn-glycerol + (12R)-hydroxy-(9Z)-octadecenoyl-CoA = 1,2,3-tri-(12R-hydroxy-9Z-octadecenoyl)-glycerol + CoA
Direction not assertedBalancedRhea 56536
1,2-dihexanoyl-sn-glycerol + (9Z)-octadecenoyl-CoA = 1,2-dihexanoyl-3-(9Z-octadecenoyl)-sn-glycerol + CoA
Direction not assertedBalancedRhea 56540
N-hexadecanoyl-1,2-diacyl-sn-glycero-3-phosphoethanolamine + H2O = N-hexadecanoylethanolamine + a 1,2-diacyl-sn-glycero-3-phosphate + H(+)
Direction not assertedBalance undeterminableRhea

56544

N-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-1,2-diacyl-sn-glycero-3-phosphoethanolamine + H2O = N-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-ethanolamine + a 1,2-diacyl-sn-glycero-3-phosphate + H(+)

Left to rightBalance undeterminableRhea 56548

L-threonyl-[rhodopsin] + ATP = O-phospho-L-threonyl-[rhodopsin] + ADP + H(+)

Direction not assertedBalance undeterminableRhea 56552

(2E,6E)-farnesyl diphosphate = delta-cadinene + diphosphate

Direction not assertedBalancedRhea 56556

[1,4-alpha-D-glucosyl](n)-L-tyrosyl-[glycogenin] + UDP-alpha-D-glucose = [1,4-alpha-D-glucosyl](n+1)-L-tyrosyl-[glycogenin] + UDP + H(+)

Left to rightBalance undeterminableRhea 56560

a globoside Gb4Cer + UDP-N-acetyl-alpha-D-galactosamine = a globoside IV3GalNAc-Gb4Cer + UDP + H(+)

Direction not assertedBalance undeterminableRhea 56568

a beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1)-ceramide + UDP-alpha-D-galactose = a globoside Gb3Cer + UDP + H(+)

Left to rightBalance undeterminableRhea 56572

a globoside Gb3Cer + UDP-N-acetyl-alpha-D-galactosamine = a globoside Gb4Cer + UDP + H(+)

Direction not assertedBalance undeterminableRhea 56576

6-thioguanine + S-adenosyl-L-methionine = 6-methylthioguanine + S-adenosyl-L-homocysteine + H(+)

Direction not assertedBalancedRhea 56580

1,2-epoxypropane + H2O = propane-1,2-diol

Direction not assertedBalancedRhea 56584

a monosubstituted aliphatic (S)-hydroxynitrile = an aldehyde + hydrogen cyanide

Direction not assertedBalance undeterminableRhea 56588

a disubstituted aliphatic (S)-hydroxynitrile = a ketone + hydrogen cyanide

Direction not assertedBalance undeterminableRhea 56592

(1S,4S)-bornane-2,5-dione + FMNH2 + O2 = (1S,4S)-5-oxo-1,2-campholide + FMN + H2O + H(+)

Direction not assertedBalancedRhea 56596

alpha-D-glucosaminyl-[heparan sulfate](n) + 3'-phosphoadenylyl sulfate = 6-sulfo-alpha-D-glucosaminyl-[heparan sulfate](n) + adenosine 3',5'-bisphosphate + H(+)

Left to rightBalance undeterminableRhea 56604

5,10-methylenetetrahydrosulfopterin + glycine + H2O = tetrahydrosulfopterin + L-serine

Direction not assertedBalancedRhea 56608

L-cysteinyl-[protein] + NAD(+) = S-(ADP-D-ribosyl)-L-cysteinyl-[protein] + nicotinamide + H(+)

Left to rightBalance undeterminableRhea 56612

(3R,6R)-1,3,4,6-tetrachlorocyclohexa-1,4-diene = 1,2,4-trichlorobenzene + chloride + H(+)

Direction not assertedBalancedRhea 56616

(3R,6R)-1,3,4,6-tetrachlorocyclohexa-1,4-diene + H2O = 2,4,5-trichlorocyclohexa-2,5-dien-1-ol + chloride + H(+)

Direction not assertedBalancedRhea 56620

2,4,5-trichlorocyclohexa-2,5-dien-1-ol + H2O = 2,5-dichlorocyclohexa-2,5-dien-1,4-diol + chloride + H(+)

Direction not assertedBalancedRhea 56624

5-chlorocarbonyl-4-hydroxy-penta-2,4-dienoate + H2O = maleylacetate + chloride + 2 H(+)

Direction not assertedBalancedRhea 56628

neryl diphosphate + H2O = 1,8-cineole + diphosphate

Direction not assertedBalancedRhea 56632

1-octadecanoyl-2-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phosphocholine + H2O = 2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphocholine + octadecanoate + H(+)

Direction not assertedBalancedRhea 56636

1,2-di-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphocholine + H2O = 2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphocholine + (9Z,12Z)-octadecadienoate + H(+)

Direction not assertedBalancedRhea 56640

a uridine in mRNA = a pseudouridine in mRNA

Left to rightBalance undeterminableRhea 56644

3-oxochol-4-en-24-oyl-CoA + NAD(+) = 3-oxochol-4,6-dien-24-oyl-CoA + NADH + H(+)

Direction not assertedBalancedRhea 56648

12alpha-hydroxy-3-oxocholan-24-oyl-CoA + NAD(+) = 12alpha-hydroxy-3-oxochol-4-en-24-oyl-CoA + NADH + H(+)

Direction not assertedBalancedRhea 56652

12alpha-hydroxy-3-oxochol-4-en-24-oyl-CoA + NAD(+) = 12alpha-hydroxy-3-oxochola-4,6-dien-24-oyl-CoA + NADH + H(+)

Direction not assertedBalancedRhea 56656

7alpha-hydroxy-3-oxochol-24-oyl-CoA + NAD(+) = 7alpha-hydroxy-3-oxochol-4-en-24-oyl-CoA + NADH + H(+)

Direction not assertedBalancedRhea 56660

7alpha,12alpha-dihydroxy-3-oxochol-24-oyl-CoA + NAD(+) = 7alpha,12alpha-dihydroxy-3-oxochol-4-en-24-oyl-CoA + NADH + H(+)

Direction not assertedBalancedRhea 56664

7beta-hydroxy-3-oxochol-24-oyl-CoA + NAD(+) = 7beta-hydroxy-3-oxochol-4-en-24-oyl-CoA + NADH + H(+)

Direction not assertedBalancedRhea 56668

dihydro-4-coumaroyl-CoA + NADP(+) = (E)-4-coumaroyl-CoA + NADPH + H(+)

Direction not assertedBalancedRhea 56672

dihydroferuloyl-CoA + NADP(+) = (E)-feruloyl-CoA + NADPH + H(+)

Direction not assertedBalancedRhea 56676

beta-dihydromenaquinone-9 + 2 reduced [2Fe-2S]-[ferredoxin] + O2 + 2 H(+) = omega-hydroxy-beta-dihydromenaquinone-9 + 2 oxidized [2Fe-2S]-[ferredoxin] + H2O

Direction not assertedBalance undeterminableRhea 56680

dihydrorhizobitoxine + 2 reduced [2Fe-2S]-[ferredoxin] + O2 + 2 H(+) = rhizobitoxine + 2 oxidized [2Fe-2S]-[ferredoxin] + 2 H2O

Direction not assertedBalance undeterminableRhea 56684

(2S)-3-(4-hydroxyphenyl)-2-isocyanopropanoate + 2-oxoglutarate + O2 = (2E)-3-(4-hydroxyphenyl)-2-isocyanoprop-2-enoate + succinate + CO2 + H2O

Direction not assertedBalancedRhea 56688

(2S)-3-(4-hydroxyphenyl)-2-isocyanopropanoate + 2-oxoglutarate + O2 + H(+) = 4-[(E)-2-isocyanoethenyl]phenol + succinate + 2 CO2 + H2O

Direction not assertedBalancedRhea 56692

D-ribulose 5-phosphate + L-tryptophan = (2S)-3-(1H-indol-3-yl)-2-isocyanopropanoate + hydroxyacetone + formaldehyde + phosphate + H2O + H(+)

Direction not assertedBalancedRhea 56696

(2S)-3-(1H-indol-3-yl)-2-isocyanopropanoate + 2-oxoglutarate + O2 + H(+) = 3-[(Z)-2-isocyanoethenyl]-1H-indole + succinate + 2 CO2 + H2O

Direction not assertedBalancedRhea 56700

(2S)-3-(1H-indol-3-yl)-2-isocyanopropanoate + 2-oxoglutarate + O2 + H(+) = 3-[(E)-2-isocyanovinyl]indole + succinate + 2 CO2 + H2O

Direction not assertedBalancedRhea 56704

beta-amyrin + reduced [NADPH--hemoprotein reductase] + O2 = 16alpha-hydroxy-beta-amyrin + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Direction not assertedBalance undeterminableRhea 56708

L-cysteinyl-[prolipoprotein] + a 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol) = an S-1,2-diacyl-sn-glyceryl-L-cysteinyl-[prolipoprotein] + sn-glycerol 1-phosphate + H(+)

Direction not assertedBalance undeterminableRhea 56712

S-(2-sulfodisulfanyl)-L-cysteinyl-[SoxY protein] + H2O = S-disulfanyl-L-cysteinyl-[SoxY protein] + sulfate + H(+)

Direction not assertedBalance undeterminableRhea 56716

L-cysteinyl-[SoxY protein] + thiosulfate + 2 Fe(III)-[cytochrome c] = S-sulfosulfanyl-L-cysteinyl-[SoxY protein] + 2 Fe(II)-[cytochrome c] + 2 H(+)

Direction not assertedBalance undeterminableRhea 56720

all-trans-beta-carotene + AH2 + O2 = 4-hydroxy-all-trans-beta-carotene + A + H2O

Direction not assertedBalancedRhea 56724

4-hydroxy-all-trans-beta-carotene + AH2 + O2 = 4,4-dihydroxy-all-trans-beta-carotene + A + H2O

Direction not assertedBalancedRhea 56728

Page 480 of 629