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Evidence

CompoundsSubstances with curated findings
OutcomesMeasured endpoints
ProteinsTransporters and enzymes
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ReactionsRhea and Human-GEM, by subsystem
ReachWhat a compound can become

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PathwaysReactions grouped under one name
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AnatomyTissues, by what is expressed there
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MaterialsSubstances that are not one molecule
AssessmentsRegulatory determinations, transcribed
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Reference

Evidence

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Reach

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Computational infrastructure for human biology, built on a provenance-aware knowledge graph. Findings retain their sources; research and simulation are the next layers.

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A reference for what the literature reports. Not medical advice.

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Index

Reactions

Reactions from Rhea and Human-GEM · Reach

reactions in the graph: 31,435

By source

Rhea18,558
Human-GEM12,877

Inferred

Reference data, not a finding. Evidence key

Filter reactions by equationSource

Reactions

23,451–23,500 of 31,435, by identifier

1,2-dihexanoyl-sn-glycero-3-phosphoethanolamine + 1,2-diheptanoyl-sn-glycero-3-phosphocholine = 1-heptanoyl-2-hexanoyl-sn-glycero-3-phosphoethanolamine + 1-hexanoyl-2-heptanoyl-sn-glycero-3-phosphocholine
Left to rightBalancedRhea 54492
ent-copalyl diphosphate = ent-atiserene + diphosphate
Direction not assertedBalancedRhea 54496
(2E,6E,10E,14E)-geranylfarnesyl diphosphate = beta-geranylfarnesene + diphosphate
Direction not assertedBalancedRhea 54500
all-trans-hexaprenyl diphosphate = beta-hexaprene + diphosphate
Direction not assertedBalancedRhea 54504
all-trans-heptaprenyl diphosphate = beta-heptaprene + diphosphate
Direction not assertedBalancedRhea 54508
peregrinol diphosphate = (13R)-9,13-epoxylabd-14-ene + diphosphate
Direction not assertedBalancedRhea 54512
8-hydroxycopalyl diphosphate = (13R)-manoyl oxide + diphosphate

Direction not assertedBalancedRhea 54516

(2E,6E,10E)-geranylgeranyl diphosphate = cycloaraneosene + diphosphate

Direction not assertedBalancedRhea 54520

methylglyoxal + acetoacetate + H(+) = 3-hydroxyhexane-2,5-dione + CO2

Direction not assertedBalancedRhea 54524

aldehydo-D-ribose 5-phosphate = D-ribose 5-phosphate

Direction not assertedBalancedRhea 54528

N-(4-oxoglutaryl)-L-cysteinylglycine + H2O = L-cysteinylglycine + 2-oxoglutarate

Direction not assertedBalancedRhea 54532

a very long-chain fatty acid + ATP + CoA = a very long-chain fatty acyl-CoA + AMP + diphosphate

Left to rightBalance undeterminableRhea 54536

a 3-O-[beta-D-galactosyl-(1->3)-N-acetyl-alpha-D-galactosaminyl]-L-threonyl-[protein] + H2O = beta-D-galactosyl-(1->3)-N-acetyl-D-galactosamine + L-threonyl-[protein]

Direction not assertedBalance undeterminableRhea 54540

1,2-dihexanoyl-sn-glycero-3-phosphoethanolamine + 2-heptanoyl-sn-glycero-3-phosphocholine = hexanoyl-sn-glycero-3-phosphoethanolamine + 1-hexanoyl-2-heptanoyl-sn-glycero-3-phosphocholine

Left to rightBalancedRhea 54544

D-xylulose 1,5-bisphosphate + H2O = D-xylulose 5-phosphate + phosphate

Direction not assertedBalancedRhea 54548

1-O-hexadecyl-2-nonadioyl-sn-glycero-3-phosphocholine + H2O = nonanedioate + 1-O-hexadecyl-sn-glycero-3-phosphocholine + H(+)

Left to rightBalancedRhea 54552

a 5'-end ribonucleotide-tRNA(His) + ATP + H(+) = a 5'-end adenosine-5'-diphospho-5'-ribonucleotide-tRNA(His) + diphosphate

Direction not assertedBalance undeterminableRhea 54556

a 5'-end adenosine-5'-diphospho-5'-ribonucleotide-tRNA(His) + GTP = a 5'-end triphospho-guanosine-ribonucleotide-tRNA(His) + AMP + H(+)

Direction not assertedBalance undeterminableRhea 54560

a 5'-end ribonucleotide-tRNA(His) + GTP + ATP + H2O = a 5'-end phospho-guanosine-ribonucleotide-tRNA(His) + AMP + 2 diphosphate + H(+)

Direction not assertedBalance undeterminableRhea 54564

a uridine in rRNA = a pseudouridine in rRNA

Direction not assertedBalance undeterminableRhea 54568

a uridine in tRNA = a pseudouridine in tRNA

Left to rightBalance undeterminableRhea 54572

an N(1)-methyladenosine in tRNA + 2-oxoglutarate + O2 = an adenosine in tRNA + formaldehyde + succinate + CO2

Left to rightBalance undeterminableRhea 54576

a 5'-end dephospho-ribonucleoside-RNA + ATP = a 5'-end 5'-phospho-ribonucleoside-RNA + ADP + H(+)

Direction not assertedBalance undeterminableRhea 54580

a guanosine in 18S rRNA + S-adenosyl-L-methionine = an N(7)-methylguanosine in 18S rRNA + S-adenosyl-L-homocysteine

Direction not assertedBalance undeterminableRhea 54584

uridine in 25S rRNA + S-adenosyl-L-methionine = N(3)-methyluridine in 25S rRNA + S-adenosyl-L-homocysteine + H(+)

Direction not assertedBalancedRhea 54588

a 5'-end diphospho-(purine-ribonucleoside) in mRNA + GTP + H(+) = a 5'-end (5'-triphosphoguanosine)-(purine-ribonucleoside) in mRNA + diphosphate

Direction not assertedBalance undeterminableRhea 54592

hexadecanoyl-CoA + 2-oxoglutarate + O2 = 2-hydroxyhexadecanoyl-CoA + succinate + CO2

Left to rightBalancedRhea 54596

octanoyl-CoA + 2-oxoglutarate + O2 = 2-hydroxyoctanoyl-CoA + succinate + CO2

Left to rightBalancedRhea 54600

decanoyl-CoA + 2-oxoglutarate + O2 = 2-hydroxydecanoyl-CoA + succinate + CO2

Left to rightBalancedRhea 54604

N(epsilon)-GMP-L-lysyl-[protein] + a 5'-end diphospho-(purine-ribonucleoside) in mRNA + 2 H(+) = a 5'-end (5'-triphosphoguanosine)-(purine-ribonucleoside) in mRNA + L-lysyl-[protein]

Direction not assertedBalance undeterminableRhea 54608

3-methylbutanoyl-CoA + 2-oxoglutarate + O2 = 2-hydroxy-3-methylbutanoyl-CoA + succinate + CO2

Left to rightBalancedRhea 54612

heptadecanoyl-CoA + 2-oxoglutarate + O2 = 2-hydroxyheptadecanoyl-CoA + succinate + CO2

Left to rightBalancedRhea 54616

eicosanoyl-CoA + 2-oxoglutarate + O2 = 2-hydroxyeicosanoyl-CoA + succinate + CO2

Left to rightBalancedRhea 54620

octadecanoyl-CoA + 2-oxoglutarate + O2 = 2-hydroxyoctadecanoyl-CoA + succinate + CO2

Left to rightBalancedRhea 54624

dodecanoyl-CoA + 2-oxoglutarate + O2 = 2-hydroxydodecanoyl-CoA + succinate + CO2

Left to rightBalancedRhea 54628

tetradecanoyl-CoA + 2-oxoglutarate + O2 = 2-hydroxytetradecanoyl-CoA + succinate + CO2

Left to rightBalancedRhea 54632

(13E)-labda-7,13-dien-15-yl diphosphate = labda-7,13(16),14-triene + diphosphate

Direction not assertedBalancedRhea 54636

(+)-copalyl diphosphate = (12E)-labda-8(17),12,14-triene + diphosphate

Direction not assertedBalancedRhea 54640

trans-4-hydroxy-L-proline = (S)-1-pyrroline-5-carboxylate + H2O + H(+)

Direction not assertedBalancedRhea 54644

ent-8alpha-hydroxylabd-13-en-15-yl diphosphate = (2E,6E,10E)-geranylgeranyl diphosphate + H2O

Direction not assertedBalancedRhea 54648

peregrinol diphosphate = (2E,6E,10E)-geranylgeranyl diphosphate + H2O

Direction not assertedBalancedRhea 54652

linalool = (2E)-geraniol

Direction not assertedBalancedRhea 54656

an aromatic (S)-hydroxynitrile = an aromatic aldehyde + hydrogen cyanide

Direction not assertedBalance undeterminableRhea 54660

(3S,22S)-2,3:22,23-diepoxysqualene = pre-alpha-onocerin

Direction not assertedBalancedRhea 54664

pre-alpha-onocerin = alpha-onocerin

Direction not assertedBalancedRhea 54668

(+)-kolavenyl diphosphate + H2O = (+)-kolavelool + diphosphate

Direction not assertedBalancedRhea 54672

(2E,6E,10E)-geranylgeranyl diphosphate = (+)-kolavenyl diphosphate

Direction not assertedBalancedRhea 54676

(2E,6E,10E)-geranylgeranyl diphosphate = (-)-kolavenyl diphosphate

Direction not assertedBalancedRhea 54684

alliin = allylsulfenate + 2-aminoprop-2-enoate

Direction not assertedBalancedRhea 54688

(2E,6E,10E)-geranylgeranyl diphosphate = (13E)-labda-7,13-dien-15-yl diphosphate

Direction not assertedBalancedRhea 54692

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