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CompoundsSubstances with curated findings
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ProteinsTransporters and enzymes
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ReactionsRhea and Human-GEM, by subsystem
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PathwaysReactions grouped under one name
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MaterialsSubstances that are not one molecule
AssessmentsRegulatory determinations, transcribed
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Reference

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Computational infrastructure for human biology, built on a provenance-aware knowledge graph. Findings retain their sources; research and simulation are the next layers.

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A reference for what the literature reports. Not medical advice.

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Index

Reactions

Reactions from Rhea and Human-GEM · Reach

reactions in the graph: 31,435

By source

Rhea18,558
Human-GEM12,877

Inferred

Reference data, not a finding. Evidence key

Filter reactions by equationSource

Reactions

23,401–23,450 of 31,435, by identifier

N-(octadecanoyl)-sphing-4-enine-1-phosphocholine + H2O = N-octadecanoylsphing-4-enine + phosphocholine + H(+)
Left to rightBalancedRhea 54284
L-tyrosyl-[protein] + ATP = O-(5'-adenylyl)-L-tyrosyl-[protein] + diphosphate
Left to rightBalance undeterminableRhea 54288
L-threonyl-[protein] + ATP = 3-O-(5'-adenylyl)-L-threonyl-[protein] + diphosphate
Left to rightBalance undeterminableRhea 54292
L-tyrosyl-[protein] + GTP = O-(5'-guanylyl)-L-tyrosyl-[protein] + diphosphate
Direction not assertedBalance undeterminableRhea 54296
chondroitin 4'-sulfate + n 3'-phosphoadenylyl sulfate = chondroitin 4',6'-bissulfate + n adenosine 3',5'-bisphosphate + n H(+)
Direction not assertedBalance undeterminableRhea 54300
dermatan 4'-sulfate + n 3'-phosphoadenylyl sulfate = dermatan 4',6'-bissulfate + n adenosine 3',5'-bisphosphate + n H(+)
Direction not assertedBalance undeterminableRhea

54304

pseudouridine(1191) in yeast 18S rRNA + S-adenosyl-L-methionine = N(1)-methylpseudouridine(1191) in yeast 18S rRNA + S-adenosyl-L-homocysteine + H(+)

Direction not assertedBalancedRhea 54308

a Delta(7)-sterol + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) = a Delta(5),Delta(7)-sterol + 2 Fe(III)-[cytochrome b5] + 2 H2O

Left to rightBalance undeterminableRhea 54320

a 2,3-bis-O-phytanyl-sn-glycerol 1-phospholipid + 8 oxidized 2[4Fe-4S]-[ferredoxin] = a 2,3-bis-O-(geranylgeranyl)-sn-glycerol 1-phospholipid + 8 reduced 2[4Fe-4S]-[ferredoxin] + 16 H(+)

Direction not assertedBalance undeterminableRhea 54324

hexadecanoyl-[ACP] + 2 NADPH + 2 H(+) = hexadecan-1-ol + holo-[ACP] + 2 NADP(+)

Direction not assertedBalance undeterminableRhea 54328

1-hexadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycerol + CDP-choline = 1-hexadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphocholine + CMP + H(+)

Left to rightBalancedRhea 54332

1,2-di-(9Z-hexadecenoyl)-sn-glycerol + CDP-choline = 1,2-di-(9Z-hexadecenoyl)-sn-glycero-3-phosphocholine + CMP + H(+)

Left to rightBalancedRhea 54336

1,2-di-(9Z-hexadecenoyl)-sn-glycerol + CDP-ethanolamine = 1,2-di-(9Z-hexadecenoyl)-sn-glycero-3-phosphoethanolamine + CMP + H(+)

Left to rightBalancedRhea 54340

1-octadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycerol + CDP-choline = 1-octadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphocholine + CMP + H(+)

Left to rightBalancedRhea 54344

1-O-hexadecyl-2-acetyl-sn-glycerol + CDP-choline = 1-O-hexadecyl-2-acetyl-sn-glycero-3-phosphocholine + CMP + H(+)

Left to rightBalancedRhea 54348

1-O-hexadecyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycerol + CDP-choline = 1-O-hexadecyl-2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphocholine + CMP + H(+)

Left to rightBalancedRhea 54352

3-methyl-2-oxobutanoate + H(+) = 2-methylpropanal + CO2

Direction not assertedBalancedRhea 54356

4-methyl-2-oxopentanoate + H(+) = 3-methylbutanal + CO2

Direction not assertedBalancedRhea 54360

2 acetaldehyde = acetoin

Direction not assertedBalancedRhea 54364

acetaldehyde + pyruvate + H(+) = acetoin + CO2

Direction not assertedBalancedRhea 54368

(2E,6E)-farnesyl diphosphate + H2O = (+)-(2S,3R,9R)-pristinol + diphosphate

Direction not assertedBalancedRhea 54372

(+)-copalyl diphosphate + H2O = nezukol + diphosphate

Direction not assertedBalancedRhea 54376

(2E,6E)-farnesyl diphosphate + H2O = 5-hydroxy-alpha-gurjunene + diphosphate

Direction not assertedBalancedRhea 54380

a 3-oxo-5alpha-steroid + NADP(+) = a 3-oxo-Delta(4)-steroid + NADPH + H(+)

Right to leftBalance undeterminableRhea 54384

1-tetradecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphocholine + H2O = 2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphocholine + tetradecanoate + H(+)

Left to rightBalancedRhea 54388

1-tetradecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphocholine + H2O = 1-tetradecanoyl-sn-glycero-3-phosphocholine + (9Z,12Z)-octadecadienoate + H(+)

Left to rightBalancedRhea 54392

1-tetradecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphocholine + H2O = 2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphocholine + tetradecanoate + H(+)

Left to rightBalancedRhea 54396

1-tetradecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphocholine + H2O = 2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphocholine + tetradecanoate + H(+)

Left to rightBalancedRhea 54400

1,2-ditetradecanoyl-sn-glycero-3-phosphocholine + H2O = 2-tetradecanoyl-sn-glycero-3-phosphocholine + tetradecanoate + H(+)

Left to rightBalancedRhea 54404

1-octadecanoyl-2-acetyl-sn-glycero-3-phosphocholine + H2O = 1-octadecanoyl-sn-glycero-3-phosphocholine + acetate + H(+)

Left to rightBalancedRhea 54408

a 3-oxo-5beta-steroid + NADP(+) = a 3-oxo-Delta(4)-steroid + NADPH + H(+)

Direction not assertedBalance undeterminableRhea 54412

5alpha-campestan-3-one + NADP(+) = campest-4-en-3-one + NADPH + H(+)

Direction not assertedBalancedRhea 54416

3',3'-c-di-AMP + H2O = 5'-O-phosphonoadenylyl-(3'->5')-adenosine + H(+)

Direction not assertedBalancedRhea 54420

L-aspartyl-[protein] + NAD(+) = 4-O-(ADP-D-ribosyl)-L-aspartyl-[protein] + nicotinamide

Left to rightBalance undeterminableRhea 54424

4-O-(ADP-D-ribosyl)-L-aspartyl-[protein] + H2O = L-aspartyl-[protein] + ADP-D-ribose + H(+)

Left to rightBalance undeterminableRhea 54428

a (2R,3S,4S)-leucoanthocyanidin + 2-oxoglutarate + O2 = a 4-H-anthocyanidin with a 3-hydroxy group + succinate + CO2 + 2 H2O

Direction not assertedBalance undeterminableRhea 54432

a (2R,3S,4S)-leucoanthocyanidin + 2-oxoglutarate + O2 = a (4S)-2,3-dehydroflavan-3,4-diol + succinate + CO2 + H2O + H(+)

Direction not assertedBalance undeterminableRhea 54436

a (4S)-2,3-dehydroflavan-3,4-diol + H(+) = a 4-H-anthocyanidin with a 3-hydroxy group + H2O

Direction not assertedBalance undeterminableRhea 54440

a (2R,3S,4S)-leucoanthocyanidin + NADP(+) = a (2R,3R)-dihydroflavonol + NADPH + H(+)

Direction not assertedBalance undeterminableRhea 54444

an N-acyl-L-alpha-aminoacyl-tRNA + H2O = an N-acyl-L-amino acid + a tRNA + H(+)

Left to rightBalance undeterminableRhea 54448

a 5,6-dihydrouridine in tRNA + NAD(+) = a uridine in tRNA + NADH + H(+)

Direction not assertedBalance undeterminableRhea 54452

1,2-ditetradecanoyl-sn-glycero-3-phosphocholine + H2O = 1-tetradecanoyl-sn-glycero-3-phosphocholine + tetradecanoate + H(+)

Left to rightBalancedRhea 54456

1-octadecanoyl-2-pentanoyl-sn-glycero-3-phosphocholine + H2O = pentanoate + 1-octadecanoyl-sn-glycero-3-phosphocholine + H(+)

Left to rightBalancedRhea 54460

1-octadecanoyl-2-hexanoyl-sn-glycero-3-phosphocholine + H2O = hexanoate + 1-octadecanoyl-sn-glycero-3-phosphocholine + H(+)

Left to rightBalancedRhea 54464

1-octadecanoyl-2-octanoyl-sn-glycero-3-phosphocholine + H2O = 1-octadecanoyl-sn-glycero-3-phosphocholine + octanoate + H(+)

Left to rightBalancedRhea 54468

1-octadecanoyl-2-nonanoyl-sn-glycero-3-phosphocholine + H2O = nonanoate + 1-octadecanoyl-sn-glycero-3-phosphocholine + H(+)

Left to rightBalancedRhea 54472

1-octadecanoyl-2-dodecanoyl-sn-glycero-3-phosphocholine + H2O = 1-octadecanoyl-sn-glycero-3-phosphocholine + dodecanoate + H(+)

Direction not assertedBalancedRhea 54476

1-octadecanoyl-2-tetradecanoyl-sn-glycero-3-phosphocholine + H2O = 1-octadecanoyl-sn-glycero-3-phosphocholine + tetradecanoate + H(+)

Direction not assertedBalancedRhea 54480

1,2-dihexanoyl-sn-glycero-3-phosphocholine + 1,2-diheptanoyl-sn-glycero-3-phosphocholine = 1-heptanoyl-2-hexanoyl-sn-glycero-3-phosphocholine + 1-hexanoyl-2-heptanoyl-sn-glycero-3-phosphocholine

Left to rightBalancedRhea 54484

1,2-diheptanoyl-sn-glycero-3-phosphocholine + 1,2-dihexadecanoyl-sn-glycero-3-phosphocholine = 1-hexadecanoyl-2-heptanoyl-sn-glycero-3-phosphocholine + 1-heptanoyl-2-hexadecanoyl-sn-glycero-3-phosphocholine

Left to rightBalancedRhea 54488

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