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ReactionsRhea and Human-GEM, by subsystem
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Reference

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Computational infrastructure for human biology, built on a provenance-aware knowledge graph. Findings retain their sources; research and simulation are the next layers.

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A reference for what the literature reports. Not medical advice.

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Index

Reactions

Reactions from Rhea and Human-GEM · Reach

reactions in the graph: 31,435

By source

Rhea18,558
Human-GEM12,877

Inferred

Reference data, not a finding. Evidence key

Filter reactions by equationSource

Reactions

23,501–23,550 of 31,435, by identifier

holo-[4-hydroxyphenylalkanoate synthase] + 4-hydroxybenzoate + ATP = 4-hydroxyphenyl-[4-hydroxyphenylalkanoate synthase] + AMP + diphosphate
Direction not assertedBalance undeterminableRhea 54696
4-hydroxybenzoyl-5'-AMP + holo-[4-hydroxyphenylalkanoate synthase] = 4-hydroxyphenyl-[4-hydroxyphenylalkanoate synthase] + AMP + H(+)
Direction not assertedBalance undeterminableRhea 54700
N-terminal N-methyl-L-alanyl-L-prolyl-L-lysyl-[protein] + S-adenosyl-L-methionine = N-terminal N,N-dimethyl-L-alanyl-L-prolyl-L-lysyl-[protein] + S-adenosyl-L-homocysteine + H(+)
Direction not assertedBalance undeterminableRhea 54704
N-terminal N,N-dimethyl-L-alanyl-L-prolyl-L-lysyl-[protein] + S-adenosyl-L-methionine = N-terminal N,N,N-trimethyl-L-alanyl-L-prolyl-L-lysyl-[protein] + S-adenosyl-L-homocysteine + H(+)
Direction not assertedBalance undeterminableRhea 54708
N-terminal L-alanyl-L-prolyl-L-lysyl-[protein] + 3 S-adenosyl-L-methionine = N-terminal N,N,N-trimethyl-L-alanyl-L-prolyl-L-lysyl-[protein] + 3 S-adenosyl-L-homocysteine + 3 H(+)
Direction not assertedBalance undeterminableRhea 54712
N-terminal N-methyl-L-seryl-L-prolyl-L-lysyl-[protein] + S-adenosyl-L-methionine = N-terminal N,N-dimethyl-L-seryl-L-prolyl-L-lysyl-[protein] + S-adenosyl-L-homocysteine + H(+)

Direction not assertedBalance undeterminableRhea 54716

N-terminal N,N-dimethyl-L-seryl-L-prolyl-L-lysyl-[protein] + S-adenosyl-L-methionine = N-terminal N,N,N-trimethyl-L-seryl-L-prolyl-L-lysyl-[protein] + S-adenosyl-L-homocysteine + H(+)

Direction not assertedBalance undeterminableRhea 54720

N-terminal L-seryl-L-prolyl-L-lysyl-[protein] + 3 S-adenosyl-L-methionine = N-terminal N,N,N-trimethyl-L-seryl-L-prolyl-L-lysyl-[protein] + 3 S-adenosyl-L-homocysteine + 3 H(+)

Direction not assertedBalance undeterminableRhea 54724

N(6)-carboxybiotinyl-L-lysyl-[protein] + acetyl-CoA = N(6)-biotinyl-L-lysyl-[protein] + malonyl-CoA

Direction not assertedBalance undeterminableRhea 54728

N-terminal N-methyl-L-prolyl-L-prolyl-L-lysyl-[protein] + S-adenosyl-L-methionine = N-terminal N,N-dimethyl-L-prolyl-L-prolyl-L-lysyl-[protein] + S-adenosyl-L-homocysteine + H(+)

Direction not assertedBalance undeterminableRhea 54732

N-terminal L-prolyl-L-prolyl-L-lysyl-[protein] + 2 S-adenosyl-L-methionine = N-terminal N,N-dimethyl-L-prolyl-L-prolyl-L-lysyl-[protein] + 2 S-adenosyl-L-homocysteine + 2 H(+)

Direction not assertedBalance undeterminableRhea 54736

9alpha,11alpha-methylene thromboxane A2 + reduced [NADPH--hemoprotein reductase] + O2 = 19-hydroxy-9alpha,11alpha-methylene thromboxane A2 + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Direction not assertedBalance undeterminableRhea 54740

9alpha,11alpha-methylene thromboxane A2 + reduced [NADPH--hemoprotein reductase] + O2 = 18-hydroxy-9alpha,11alpha-methylene thromboxane A2 + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Direction not assertedBalance undeterminableRhea 54744

firefly L-luciferin + ATP + CoA = L-firefly luciferyl-CoA + AMP + diphosphate

Direction not assertedBalancedRhea 54748

methanophenazine + reduced coenzyme F420-(gamma-L-Glu)(n) = dihydromethanophenazine + oxidized coenzyme F420-(gamma-L-Glu)(n) + H(+)

Direction not assertedBalance undeterminableRhea 54752

deamido-NAD(+) + hydrogencarbonate = pyridinium-3,5-dicarboxylate mononucleotide + AMP + 2 H(+)

Direction not assertedBalancedRhea 54756

pyridinium-3,5-dicarboxylate mononucleotide + ATP + H(+) = 5-carboxy-1-(5-O-phospho-beta-D-ribofuranosyl)pyridinium-3-carbonyl adenylate + diphosphate

Direction not assertedBalancedRhea 54760

5-carboxy-1-(5-O-phospho-beta-D-ribofuranosyl)pyridinium-3-carbonyl adenylate + [LarE protein]-L-cysteine = [LarE protein]-S-[5-carboxy-1-(5-O-phosphono-beta-D-ribofuranosyl)pyridinium-3-carbonyl]-L-cysteine + AMP + H(+)

Direction not assertedBalance undeterminableRhea 54764

[LarE protein]-S-[5-carboxy-1-(5-O-phosphono-beta-D-ribofuranosyl)pyridinium-3-carbonyl]-L-cysteine = [LarE protein]-dehydroalanine + pyridinium-3-carboxylate-5-thiocarboxylate mononucleotide + H(+)

Direction not assertedBalance undeterminableRhea 54768

pyridinium-3-carboxylate-5-thiocarboxylate mononucleotide + ATP + H(+) = 1-(5-O-phospho-beta-D-ribofuranosyl)-5-(sulfanylcarbonyl)pyridinium-3-carbonyl adenylate + diphosphate

Direction not assertedBalancedRhea 54772

1-(5-O-phospho-beta-D-ribofuranosyl)-5-(sulfanylcarbonyl)pyridinium-3-carbonyl adenylate + [LarE protein]-L-cysteine = [LarE protein]-S-[1-(5-O-phosphono-beta-D-ribofuranosyl)-5-(sulfanylcarbonyl)pyridinium-3-carbonyl]-L-cysteine + AMP + H(+)

Direction not assertedBalance undeterminableRhea 54776

[LarE protein]-S-[1-(5-O-phosphono-beta-D-ribofuranosyl)-5-(sulfanylcarbonyl)pyridinium-3-carbonyl]-L-cysteine = pyridinium-3,5-bisthiocarboxylate mononucleotide + [LarE protein]-dehydroalanine + H(+)

Direction not assertedBalance undeterminableRhea 54780

Ni(II)-pyridinium-3,5-bisthiocarboxylate mononucleotide = pyridinium-3,5-bisthiocarboxylate mononucleotide + Ni(2+)

Direction not assertedBalancedRhea 54784

pyridinium-3,5-dicarboxylate mononucleotide + [LarE protein]-L-cysteine + ATP = [LarE protein]-dehydroalanine + pyridinium-3-carboxylate-5-thiocarboxylate mononucleotide + AMP + diphosphate + H(+)

Direction not assertedBalance undeterminableRhea 54788

N(7)-methyl-GTP + L-histidyl-[protein] = N(tele)-(N(7)-methylguanosine 5'-phospho)-L-histidyl-[protein] + diphosphate

Direction not assertedBalance undeterminableRhea 54792

a (2R,3S)-2-alkyl-3-hydroxyalkanoate + NADP(+) = an (R)-2-alkyl-3-oxoalkanoate + NADPH + H(+)

Direction not assertedBalance undeterminableRhea 54796

N(tele)-(N(7)-methylguanosine 5'-phospho)-L-histidyl-[protein] + a 5'-end diphospho-(purine-ribonucleoside) in mRNA + H(+) = a 5'-end (N(7)-methyl 5'-triphosphoguanosine)-(purine-ribonucleoside) in mRNA + L-histidyl-[protein]

Direction not assertedBalance undeterminableRhea 54800

2 4-sulfanylbutanoate + NAD(+) = 4,4'-disulfanyldibutanoate + NADH + H(+)

Direction not assertedBalancedRhea 54804

L-isoleucine-(+)-7-isojasmonate + NADPH + O2 + H(+) = L-isoleucine-(+)-12-hydroxy-7-isojasmonate + NADP(+) + H2O

Direction not assertedBalancedRhea 54808

(+)-7-isojasmonate + L-isoleucine + ATP = L-isoleucine-(+)-7-isojasmonate + AMP + diphosphate + H(+)

Direction not assertedBalancedRhea 54812

L-glutaminyl-[protein] + L-lysyl-[protein] = [protein]-L-lysyl-N(6)-5-L-glutamyl-[protein] + NH4(+)

Left to rightBalance undeterminableRhea 54816

a beta-D-Gal-(1->4)-beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-beta-D-GlcNAc derivative + UDP-N-acetyl-alpha-D-glucosamine = a beta-D-Gal-(1->4)-beta-D-GlcNAc-(1->3)-[beta-D-GlcNAc-(1->6)]-beta-D-Gal-(1->4)-N-acetyl-beta-D-GlcNAc derivative + UDP + H(+)

Direction not assertedBalance undeterminableRhea 54820

N-{alpha-Glc-(1->3)-alpha-Man-(1->2)-alpha-Man-(1->2)-alpha-Man-(1->3)-[alpha-Man-(1->2)-alpha-Man-(1->3)-[alpha-Man-(1->2)-alpha-Man-(1->6)]-alpha-Man-(1->6)]-beta-Man-(1->4)-beta-GlcNAc-(1->4)-beta-GlcNAc}-L-asparaginyl-[protein] + H2O = alpha-D-glucosyl-(1->3)-D-mannopyranose + N(4)-{alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlaNAc-(1->4)-beta-D-GlcNAc}-L-asparaginyl-[protein] (N-glucan mannose isomer 8A1,2,3B1,2)

Direction not assertedBalance undeterminableRhea 54824

dimethylamine + NADPH + O2 + H(+) = methylamine + formaldehyde + NADP(+) + H2O

Direction not assertedBalancedRhea 54828

a jasmonyl-L-amino acid + reduced [NADPH--hemoprotein reductase] + O2 = a 12-hydroxyjasmonyl-L-alpha-amino acid + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Direction not assertedBalance undeterminableRhea 54832

heptan-2-one + NADPH + O2 + H(+) = pentyl acetate + NADP(+) + H2O

Left to rightBalancedRhea 54836

octan-3-one + NADPH + O2 + H(+) = pentyl propanoate + NADP(+) + H2O

Left to rightBalancedRhea 54840

hexan-3-one + NADPH + O2 + H(+) = ethyl butanoate + NADP(+) + H2O

Left to rightBalancedRhea 54844

hexan-3-one + NADPH + O2 + H(+) = propyl propanoate + NADP(+) + H2O

Left to rightBalancedRhea 54848

heptan-4-one + NADPH + O2 + H(+) = propyl butanoate + NADP(+) + H2O

Left to rightBalancedRhea 54852

octan-3-one + NADPH + O2 + H(+) = ethyl hexanoate + NADP(+) + H2O

Left to rightBalancedRhea 54856

(2E)-geranial + NADPH + O2 + H(+) = (1E)-2,6-dimethylhepta-1,5-dien-1-yl formate + NADP(+) + H2O

Left to rightBalancedRhea 54860

sulcatone + NADPH + O2 + H(+) = 4-methylpent-3-en-1-yl acetate + NADP(+) + H2O

Left to rightBalancedRhea 54864

(2E)-butenoyl-[ACP] + NADH + H(+) = butanoyl-[ACP] + NAD(+)

Direction not assertedBalance undeterminableRhea 54868

(1S,4R)-menthone + NADPH + O2 + H(+) = (4S,7R)-7-isopropyl-4-methyloxepan-2-one + NADP(+) + H2O

Direction not assertedBalancedRhea 54872

(4S,7S)-7-hydroxy-4-isopropenyl-7-methyloxepan-2-one = (3S)-3-isopropenyl-6-oxoheptanoate + H(+)

Direction not assertedBalancedRhea 54876

(4R,7R)-7-hydroxy-4-isopropenyl-7-methyloxepan-2-one = (3R)-3-isopropenyl-6-oxoheptanoate + H(+)

Direction not assertedBalancedRhea 54880

L-arginyl-[protein] + NADP(+) = N(omega)-(2'-phospho-ADP-D-ribosyl)-L-arginyl-[protein] + nicotinamide + H(+)

Direction not assertedBalance undeterminableRhea 54884

(1S,2S)-OPC-8 + ATP + CoA = OPC8-CoA + AMP + diphosphate

Direction not assertedBalancedRhea 54888

[LarE protein]-L-cysteine + pyridinium-3-carboxylate-5-thiocarboxylate mononucleotide + ATP = pyridinium-3,5-bisthiocarboxylate mononucleotide + [LarE protein]-dehydroalanine + AMP + diphosphate + H(+)

Direction not assertedBalance undeterminableRhea 54892

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