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CompoundsSubstances with curated findings
OutcomesMeasured endpoints
ProteinsTransporters and enzymes
InteractionsPairs that share biology
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ReactionsRhea and Human-GEM, by subsystem
ReachWhat a compound can become

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PathwaysReactions grouped under one name
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AnatomyTissues, by what is expressed there
Cell typesCells, by what is expressed there
OrganismsSpecies a compound is prepared from
MaterialsSubstances that are not one molecule
AssessmentsRegulatory determinations, transcribed
DiseasesFeatures, genes, and where each sits

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Reference

Evidence

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Computational infrastructure for human biology, built on a provenance-aware knowledge graph. Findings retain their sources; research and simulation are the next layers.

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A reference for what the literature reports. Not medical advice.

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Index

Reactions

Reactions from Rhea and Human-GEM · Reach

reactions in the graph: 31,435

By source

Rhea18,558
Human-GEM12,877

Inferred

Reference data, not a finding. Evidence key

Filter reactions by equationSource

Reactions

22,751–22,800 of 31,435, by identifier

D-5-phenylhydantoin + H2O = N-carbamoyl-D-phenylglycine + H(+)
Direction not assertedBalancedRhea 51664
mevastatin + 2 reduced [2Fe-2S]-[ferredoxin] + O2 + 2 H(+) = pravastatin lactone + 2 oxidized [2Fe-2S]-[ferredoxin] + H2O
Direction not assertedBalance undeterminableRhea 51668
glyoxal + H2O = glycolate + H(+)
Direction not assertedBalancedRhea 51672
[protein]-disulfide + hydrogen sulfide + 2 A + 3 H2O = [protein]-dithiol + sulfite + 2 AH2 + H(+)
Direction not assertedBalance undeterminableRhea 51676
(2E,6E)-farnesol + CTP = (2E,6E)-farnesyl phosphate + CDP + H(+)
Direction not assertedBalancedRhea 51680
(2E,6E)-farnesyl phosphate + CTP = CDP + (2E,6E)-farnesyl diphosphate
Direction not assertedBalancedRhea 51684
galactitol + NAD(+) = keto-L-tagatose + NADH + H(+)

Direction not assertedBalancedRhea 51688

prephenate + S-adenosyl-L-methionine = carboxy-S-adenosyl-L-methionine + 3-phenylpyruvate + H2O

Direction not assertedBalancedRhea 51692

desmethylxanthohumol + S-adenosyl-L-methionine = xanthohumol + S-adenosyl-L-homocysteine + H(+)

Direction not assertedBalancedRhea 51696

xanthogalenol + S-adenosyl-L-methionine = 4'-O-methylxanthohumol + S-adenosyl-L-homocysteine + H(+)

Direction not assertedBalancedRhea 51700

xanthohumol + S-adenosyl-L-methionine = 4-O-methylxanthohumol + S-adenosyl-L-homocysteine + H(+)

Direction not assertedBalancedRhea 51704

D-altritol + NAD(+) = keto-D-tagatose + NADH + H(+)

Direction not assertedBalancedRhea 51708

keto-D-tagatose 6-phosphate = keto-D-fructose 6-phosphate

Direction not assertedBalancedRhea 51712

hexadecanoate(out) + ATP(in) + CoA(in) + H(+)(out) = hexadecanoyl-CoA(in) + AMP(in) + diphosphate(in) + H(+)(in)

Direction not assertedBalancedTransportRhea 51716

octadecanoate(out) + ATP(in) + CoA(in) + H(+)(out) = octadecanoyl-CoA(in) + AMP(in) + diphosphate(in) + H(+)(in)

Direction not assertedBalancedTransportRhea 51720

P(1),P(6)-bis(5'-adenosyl) hexaphosphate + H2O = adenosine 5'-tetraphosphate + ADP + 2 H(+)

Direction not assertedBalancedRhea 51724

dihydroxyacetone phosphate + H2O = dihydroxyacetone + phosphate

Direction not assertedBalancedRhea 51728

glandicoline B + S-adenosyl-L-methionine = meleagrin + S-adenosyl-L-homocysteine + H(+)

Direction not assertedBalancedRhea 51732

L-lysyl-[protein] + S-adenosyl-L-methionine = N(6)-methyl-L-lysyl-[protein] + S-adenosyl-L-homocysteine + H(+)

Left to rightBalance undeterminableRhea 51736

lipid A + a 1,2-diacyl-sn-glycero-3-phosphoethanolamine + H(+) = lipid A 4'-(2-aminoethyl diphosphate) + a 1,2-diacyl-sn-glycerol

Direction not assertedBalance undeterminableRhea 51740

lipid A + a 1,2-diacyl-sn-glycero-3-phosphoethanolamine + H(+) = lipid A 1-(2-aminoethyl diphosphate) + a 1,2-diacyl-sn-glycerol

Direction not assertedBalance undeterminableRhea 51744

lipid A + 4-amino-4-deoxy-alpha-L-arabinopyranosyl di-trans,octa-cis-undecaprenyl phosphate = 4-amino-4-deoxy-beta-L-arabinopyranosyl-lipid A + di-trans,octa-cis-undecaprenyl phosphate

Direction not assertedBalance undeterminableRhea 51748

a 2-acylphloroglucinol + dimethylallyl diphosphate = a 2-acyl-4-prenylphloroglucinol + diphosphate

Direction not assertedBalance undeterminableRhea 51752

a 2-acyl-4-prenylphloroglucinol + dimethylallyl diphosphate = a 2-acyl-4,6-diprenylphloroglucinol + diphosphate

Direction not assertedBalance undeterminableRhea 51756

a 2-acyl-4,6-diprenylphloroglucinol + dimethylallyl diphosphate = a 2-acyl-4,6,6-triprenylphloroglucinol + diphosphate

Direction not assertedBalance undeterminableRhea 51760

phlorisovalerophenone + dimethylallyl diphosphate = 4-prenylphlorisovalerophenone + diphosphate

Direction not assertedBalancedRhea 51764

2-methyl-1-(2,4,6-trihydroxyphenyl)butan-1-one + dimethylallyl diphosphate = 4-prenylphlormethylbutanophenone + diphosphate

Direction not assertedBalancedRhea 51768

phlorisobutanophenone + dimethylallyl diphosphate = 4-prenylphlorisobutanophenone + diphosphate

Direction not assertedBalancedRhea 51772

4-prenylphlorisobutanophenone + dimethylallyl diphosphate = deoxycohumulone + diphosphate

Direction not assertedBalancedRhea 51776

4-prenylphlormethylbutanophenone + dimethylallyl diphosphate = deoxyadlupulone + diphosphate

Direction not assertedBalancedRhea 51780

4-prenylphlorisovalerophenone + dimethylallyl diphosphate = deoxyhumulone + diphosphate

Direction not assertedBalancedRhea 51784

2-hydroxybenzoyl-5'-AMP + CoA = 2-hydroxybenzoyl-CoA + AMP + H(+)

Direction not assertedBalancedRhea 51788

salicylate + NADH + O2 + H(+) = 2,3-dihydroxybenzoate + NAD(+) + H2O

Direction not assertedBalancedRhea 51792

deoxycohumulone + dimethylallyl diphosphate = colupulone + diphosphate + H(+)

Direction not assertedBalancedRhea 51796

deoxyadlupulone + dimethylallyl diphosphate = adlupulone + diphosphate + H(+)

Direction not assertedBalancedRhea 51800

deoxyhumulone + dimethylallyl diphosphate = lupulone + diphosphate + H(+)

Direction not assertedBalancedRhea 51804

(9Z)-octadecenoate(out) + ATP(in) + CoA(in) + H(+)(out) = (9Z)-octadecenoyl-CoA(in) + AMP(in) + diphosphate(in) + H(+)(in)

Direction not assertedBalancedTransportRhea 51808

tetradecanoate(out) + ATP(in) + CoA(in) + H(+)(out) = tetradecanoyl-CoA(in) + AMP(in) + diphosphate(in) + H(+)(in)

Direction not assertedBalancedTransportRhea 51812

dodecanoate(out) + ATP(in) + CoA(in) + H(+)(out) = dodecanoyl-CoA(in) + AMP(in) + diphosphate(in) + H(+)(in)

Direction not assertedBalancedTransportRhea 51816

decanoate(out) + ATP(in) + CoA(in) + H(+)(out) = decanoyl-CoA(in) + AMP(in) + diphosphate(in) + H(+)(in)

Direction not assertedBalancedTransportRhea 51820

octanoate(out) + ATP(in) + CoA(in) + H(+)(out) = octanoyl-CoA(in) + AMP(in) + diphosphate(in) + H(+)(in)

Direction not assertedBalancedTransportRhea 51824

docosanoate(out) + ATP(in) + CoA(in) + H(+)(out) = docosanoyl-CoA(in) + AMP(in) + diphosphate(in) + H(+)(in)

Direction not assertedBalancedTransportRhea 51828

tetracosanoate(out) + ATP(in) + CoA(in) + H(+)(out) = tetracosanoyl-CoA(in) + AMP(in) + diphosphate(in) + H(+)(in)

Direction not assertedBalancedTransportRhea 51832

(9Z)-tetradecenoate(out) + ATP(in) + CoA(in) + H(+)(out) = (9Z)-tetradecenoyl-CoA(in) + AMP(in) + diphosphate(in) + H(+)(in)

Direction not assertedBalancedTransportRhea 51836

tauroallocholate(out) + 2 Na(+)(out) = tauroallocholate(in) + 2 Na(+)(in)

Direction not assertedBalancedTransportRhea 51840

(9Z)-hexadecenoate(out) + ATP(in) + CoA(in) + H(+)(out) = (9Z)-hexadecenoyl-CoA(in) + AMP(in) + diphosphate(in) + H(+)(in)

Direction not assertedBalancedTransportRhea 51844

8-methylmenaquinone-6 + succinate = 8-methylmenaquinol-6 + fumarate

Direction not assertedBalancedRhea 51848

(9Z,12Z)-octadecadienoate(out) + ATP(in) + CoA(in) + H(+)(out) = (9Z,12Z)-octadecadienoyl-CoA(in) + AMP(in) + diphosphate(in) + H(+)(in)

Direction not assertedBalancedTransportRhea 51852

(E)-hexadec-2-enoate(out) + ATP(in) + CoA(in) + H(+)(out) = (2E)-hexadecenoyl-CoA(in) + AMP(in) + diphosphate(in) + H(+)(in)

Direction not assertedBalancedTransportRhea 51856

umbelliferone + (2E)-geranyl diphosphate = 8-geranylumbelliferone + diphosphate

Direction not assertedBalancedRhea 51860

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