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ReactionsRhea and Human-GEM, by subsystem
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Reference

Evidence

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Computational infrastructure for human biology, built on a provenance-aware knowledge graph. Findings retain their sources; research and simulation are the next layers.

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A reference for what the literature reports. Not medical advice.

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Index

Reactions

Reactions from Rhea and Human-GEM · Reach

reactions in the graph: 31,435

By source

Rhea18,558
Human-GEM12,877

Inferred

Reference data, not a finding. Evidence key

Filter reactions by equationSource

Reactions

22,701–22,750 of 31,435, by identifier

deoxycholate + reduced [NADPH--hemoprotein reductase] + O2 = 1beta-hydroxydeoxycholate + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)
Direction not assertedBalance undeterminableRhea 51464
(R)-lactate + a quinone = a quinol + pyruvate
Direction not assertedBalance undeterminableRhea 51468
(5Z,8Z,11Z,14Z)-eicosatetraenoate + reduced [NADPH--hemoprotein reductase] + O2 = 14,15-epoxy-(5Z,8Z,11Z)-eicosatrienoate + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)
Left to rightBalance undeterminableRhea 51472
a ribonucleoside 5'-triphosphate + formate + H(+) = a 2'-deoxyribonucleoside 5'-triphosphate + CO2 + H2O
Direction not assertedBalance undeterminableRhea 51476
(5Z,8Z,11Z,14Z)-eicosatetraenoate + reduced [NADPH--hemoprotein reductase] + O2 = 11,12-epoxy-(5Z,8Z,14Z)-eicosatrienoate + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)
Left to rightBalance undeterminableRhea 51480
(5Z,8Z,11Z,14Z)-eicosatetraenoate + reduced [NADPH--hemoprotein reductase] + O2 = 12-hydroxy-(5Z,8Z,10E,14Z)-eicosatetraenoate + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Direction not assertedBalance undeterminableRhea 51484

archaetidylserine + H(+) = archaetidylethanolamine + CO2

Direction not assertedBalancedRhea 51488

all-trans-retinoate + reduced [NADPH--hemoprotein reductase] + O2 = all-trans-(4S)-hydroxyretinoate + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Left to rightBalance undeterminableRhea 51492

a sphingoid base + ATP = a sphingoid 1-phosphate + ADP + H(+)

Left to rightBalance undeterminableRhea 51496

N-acetyl-D-muramate + ATP = N-acetyl-D-muramate 6-phosphate + ADP + H(+)

Direction not assertedBalancedRhea 51500

a 3'-hydro-2'-hydroxy-beta-oxodihydrochalcone + UDP-alpha-D-glucose = a 3'-(beta-D-glucopyranosyl)-2'-hydroxy-beta-oxodihydrochalcone + UDP + H(+)

Direction not assertedBalance undeterminableRhea 51504

L-proline + 2-oxoglutarate + O2 = trans-4-hydroxy-L-proline + succinate + CO2

Direction not assertedBalancedRhea 51508

oxamate + H2O = oxalate + NH4(+)

Direction not assertedBalancedRhea 51512

(R)-reticuline + S-adenosyl-L-methionine = (R)-tembetarine + S-adenosyl-L-homocysteine + H(+)

Direction not assertedBalancedRhea 51516

(S)-reticuline + S-adenosyl-L-methionine = (S)-tembetarine + S-adenosyl-L-homocysteine + H(+)

Direction not assertedBalancedRhea 51520

(S)-corytuberine + S-adenosyl-L-methionine = magnoflorine + S-adenosyl-L-homocysteine

Direction not assertedBalancedRhea 51524

vanillate + H(+) = guaiacol + CO2

Direction not assertedBalancedRhea 51528

urate + NADPH + O2 + H(+) = 5-hydroxyisourate + NADP(+) + H2O

Direction not assertedBalancedRhea 51532

L-tyrosyl-[protein] + UDP-N-acetyl-alpha-D-glucosamine = O-(N-acetyl-alpha-D-glucosaminyl)-L-tyrosyl-[protein] + UDP + H(+)

Direction not assertedBalance undeterminableRhea 51536

(S)-reticuline + reduced [NADPH--hemoprotein reductase] + O2 = (S)-corytuberine + oxidized [NADPH--hemoprotein reductase] + 2 H2O + 2 H(+)

Direction not assertedBalance undeterminableRhea 51540

D-ribulose = D-xylulose

Direction not assertedBalancedRhea 51544

(S)-tetrahydropapaverine + S-adenosyl-L-methionine = (S)-N-methyltetrahydropapaverine + S-adenosyl-L-homocysteine + H(+)

Direction not assertedBalancedRhea 51548

D-sorbitol + NADP(+) = L-xylo-3-hexulose + NADPH + H(+)

Direction not assertedBalancedRhea 51552

(S)-glaucine + S-adenosyl-L-methionine = (S)-N-methylglaucine + S-adenosyl-L-homocysteine + H(+)

Direction not assertedBalancedRhea 51556

(S)-bulbocapnine + S-adenosyl-L-methionine = (S)-N-methylbulbocapnine + S-adenosyl-L-homocysteine + H(+)

Direction not assertedBalancedRhea 51560

cholest-4-en-3-one + 6 reduced [2Fe-2S]-[ferredoxin] + 3 O2 + 5 H(+) = (25S)-3-oxocholest-4-en-26-oate + 6 oxidized [2Fe-2S]-[ferredoxin] + 4 H2O

Direction not assertedBalance undeterminableRhea 51564

(25S)-3-oxocholest-4-en-26-ol + 2 reduced [2Fe-2S]-[ferredoxin] + O2 + 2 H(+) = (25S)-3-oxocholest-4-en-26-al + 2 oxidized [2Fe-2S]-[ferredoxin] + 2 H2O

Direction not assertedBalance undeterminableRhea 51568

(25S)-3-oxocholest-4-en-26-al + 2 reduced [2Fe-2S]-[ferredoxin] + O2 + H(+) = (25S)-3-oxocholest-4-en-26-oate + 2 oxidized [2Fe-2S]-[ferredoxin] + H2O

Direction not assertedBalance undeterminableRhea 51572

phloretin + UDP-alpha-D-glucose = phlorizin + UDP + H(+)

Direction not assertedBalancedRhea 51576

a fatty acid(out) + ATP(in) + CoA(in) + H(+)(out) = a fatty acyl-CoA(in) + AMP(in) + diphosphate(in) + H(+)(in)

Direction not assertedBalance undeterminableTransportRhea 51580

4-(trimethylamino)butanoyl-CoA + oxidized [electron-transfer flavoprotein] + H(+) = crotonobetainyl-CoA + reduced [electron-transfer flavoprotein]

Direction not assertedBalance undeterminableRhea 51584

isopyridoxal + NAD(+) = 5-pyridoxolactone + NADH + H(+)

Direction not assertedBalancedRhea 51588

toluene + 2 reduced [2Fe-2S]-[ferredoxin] + O2 + 2 H(+) = benzyl alcohol + 2 oxidized [2Fe-2S]-[ferredoxin] + H2O

Direction not assertedBalance undeterminableRhea 51592

p-xylene + 2 reduced [2Fe-2S]-[ferredoxin] + O2 + 2 H(+) = 4-methylbenzyl alcohol + 2 oxidized [2Fe-2S]-[ferredoxin] + H2O

Direction not assertedBalance undeterminableRhea 51596

m-xylene + 2 reduced [2Fe-2S]-[ferredoxin] + O2 + 2 H(+) = 3-methylbenzyl alcohol + 2 oxidized [2Fe-2S]-[ferredoxin] + H2O

Direction not assertedBalance undeterminableRhea 51600

p-cymene + 2 reduced [2Fe-2S]-[ferredoxin] + O2 + 2 H(+) = 4-isopropylbenzyl alcohol + 2 oxidized [2Fe-2S]-[ferredoxin] + H2O

Direction not assertedBalance undeterminableRhea 51604

(R)-2-hydroxyglutarate + pyruvate = (R)-lactate + 2-oxoglutarate

Direction not assertedBalancedRhea 51608

(R)-2-hydroxyglutarate + oxaloacetate = (R)-malate + 2-oxoglutarate

Direction not assertedBalancedRhea 51612

formate + ATP + H(+) = dATP + CO2 + H2O

Direction not assertedBalancedRhea 51616

CTP + formate + H(+) = dCTP + CO2 + H2O

Direction not assertedBalancedRhea 51620

formate + GTP + H(+) = dGTP + CO2 + H2O

Direction not assertedBalancedRhea 51624

UTP + formate + H(+) = dUTP + CO2 + H2O

Direction not assertedBalancedRhea 51628

all-trans-(4S)-hydroxyretinoate + reduced [NADPH--hemoprotein reductase] + O2 = all-trans-(4S,16)-dihydroxyretinoate + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Left to rightBalance undeterminableRhea 51632

selenite + a quinone + H2O = selenate + a quinol

Direction not assertedBalance undeterminableRhea 51636

(9Z,12Z)-octadecadienoate + O2 = (11R)-hydroperoxy-(9Z,12Z)-octadecadienoate

Direction not assertedBalancedRhea 51640

cholesterol + NADH + O2 + H(+) = 7-dehydrocholesterol + NAD(+) + 2 H2O

Direction not assertedBalancedRhea 51644

N(6)-acetyl-L-lysyl-[protein] + O2 + H2O = acetamide + (S)-2-amino-6-oxohexanoyl-[protein] + H2O2

Direction not assertedBalance undeterminableRhea 51648

D-mannonate + NAD(+) = keto-D-tagaturonate + NADH + H(+)

Direction not assertedBalancedRhea 51652

keto-D-tagaturonate = keto-D-fructuronate

Direction not assertedBalancedRhea 51656

an N-(1,2-saturated acyl)sphinganine + NADPH + O2 + H(+) = an N-(2-hydroxyacyl)-sphinganine + NADP(+) + H2O

Direction not assertedBalance undeterminableRhea 51660

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