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CompoundsSubstances with curated findings
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ProteinsTransporters and enzymes
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ReactionsRhea and Human-GEM, by subsystem
ReachWhat a compound can become

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PathwaysReactions grouped under one name
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MaterialsSubstances that are not one molecule
AssessmentsRegulatory determinations, transcribed
DiseasesFeatures, genes, and where each sits

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Reference

Evidence

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Reactions
Reach

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Organisms
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Computational infrastructure for human biology, built on a provenance-aware knowledge graph. Findings retain their sources; research and simulation are the next layers.

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A reference for what the literature reports. Not medical advice.

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Index

Reactions

Reactions from Rhea and Human-GEM · Reach

reactions in the graph: 31,435

By source

Rhea18,558
Human-GEM12,877

Inferred

Reference data, not a finding. Evidence key

Filter reactions by equationSource

Reactions

22,351–22,400 of 31,435, by identifier

glycocholate(in) + ATP + H2O = glycocholate(out) + ADP + phosphate + H(+)
Left to rightBalancedTransportRhea 50056
glycochenodeoxycholate(in) + ATP + H2O = glycochenodeoxycholate(out) + ADP + phosphate + H(+)
Left to rightBalancedTransportRhea 50060
taurochenodeoxycholate(in) + ATP + H2O = taurochenodeoxycholate(out) + ADP + phosphate + H(+)
Left to rightBalancedTransportRhea 50064
glycoursodeoxycholate(in) + ATP + H2O = glycoursodeoxycholate(out) + ADP + phosphate + H(+)
Left to rightBalancedTransportRhea 50068
tauroursodeoxycholate(in) + ATP + H2O = tauroursodeoxycholate(out) + ADP + phosphate + H(+)
Left to rightBalancedTransportRhea 50072
(5Z,8Z,11Z)-eicosatrienoate + reduced [NADPH--hemoprotein reductase] + O2 = 19-hydroxy-(5Z,8Z,11Z)-eicosatrienoate + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)
Left to rightBalance undeterminable

Rhea 50076

taurodeoxycholate(in) + ATP + H2O = taurodeoxycholate(out) + ADP + phosphate + H(+)

Left to rightBalancedTransportRhea 50080

taurolithocholate 3-sulfate(in) + ATP + H2O = taurolithocholate 3-sulfate(out) + ADP + phosphate + H(+)

Left to rightBalancedTransportRhea 50084

(4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoate + reduced [NADPH--hemoprotein reductase] + O2 = 21-hydroxy-(4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoate + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Left to rightBalance undeterminableRhea 50088

a fatty acyl-CoA + taurine = an N-fatty acyl-taurine + CoA + H(+)

Direction not assertedBalance undeterminableRhea 50092

tetradecanoate + reduced [NADPH--hemoprotein reductase] + O2 = 13-hydroxytetradecanoate + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Left to rightBalance undeterminableRhea 50096

dodecanoyl-CoA + taurine = N-dodecanoyl-taurine + CoA + H(+)

Direction not assertedBalancedRhea 50100

tetradecanoyl-CoA + taurine = N-tetradecanoyl-taurine + CoA + H(+)

Direction not assertedBalancedRhea 50104

taurine + hexadecanoyl-CoA = N-hexadecanoyl-taurine + CoA + H(+)

Direction not assertedBalancedRhea 50108

taurine + octadecanoyl-CoA = N-octadecanoyl-taurine + CoA + H(+)

Direction not assertedBalancedRhea 50112

eicosanoyl-CoA + taurine = N-eicosanoyl-taurine + CoA + H(+)

Direction not assertedBalancedRhea 50116

tetracosanoyl-CoA + taurine = N-tetracosanoyl-taurine + CoA + H(+)

Direction not assertedBalancedRhea 50120

resolvin D1 + NAD(+) = 8-oxoresolvin D1 + NADH + H(+)

Left to rightBalancedRhea 50124

resolvin D1 + NAD(+) = 17-oxoresolvin D1 + NADH + H(+)

Left to rightBalancedRhea 50128

ethyl hexadecanoate + H2O = ethanol + hexadecanoate + H(+)

Direction not assertedBalancedRhea 50132

ethyl (9Z)-octadecenoate + H2O = ethanol + (9Z)-octadecenoate + H(+)

Direction not assertedBalancedRhea 50136

(15S)-hydroperoxy-(5Z,8Z,11Z,13E)-eicosatetraenoate = (14S,15S)-epoxy-(5Z,8Z,10E,12E)-eicosatetraenoate + H2O

Left to rightBalancedRhea 50140

ethyl (9Z)-hexadecenoate + H2O = (9Z)-hexadecenoate + ethanol + H(+)

Direction not assertedBalancedRhea 50144

a fatty acid ethyl ester + H2O = ethanol + a fatty acid + H(+)

Direction not assertedBalance undeterminableRhea 50148

(15R)-hydroperoxy-(5Z,8Z,11Z,13E)-eicosatetraenoate = 15-oxo-(5Z,8Z,11Z,13E)-eicosatetraenoate + H2O

Left to rightBalancedRhea 50152

N-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-taurine + O2 = N-(15S)-hydroperoxy-(5Z,8Z,11Z,13E)-eicosatetraenoyl-taurine

Left to rightBalancedRhea 50156

N-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-taurine + O2 = N-(12S)-hydroperoxy-(5Z,8Z,10E,14Z)-eicosatetraenoyl-taurine

Left to rightBalancedRhea 50160

(5Z,8Z,11Z)-eicosatrienoate + reduced [NADPH--hemoprotein reductase] + O2 = 20-hydroxy-(5Z,8Z,11Z)-eicosatrienoate + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Left to rightBalance undeterminableRhea 50164

N-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-glycine + O2 = N-(12S)-hydroperoxy-(5Z,8Z,10E,14Z)-eicosatetraenoyl-glycine

Left to rightBalancedRhea 50168

N-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-L-alanine + O2 = N-(12S)-hydroperoxy-(5Z,8Z,10E,14Z)-eicosatetraenoyl-alanine

Left to rightBalancedRhea 50172

N-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-gamma-aminobutanoate + O2 = N-(12S)-hydroperoxy-(5Z,8Z,10E,14Z)-eicosatetraenoyl-gamma-aminobutanoate

Left to rightBalancedRhea 50176

N-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-gamma-aminobutanoate + O2 = N-(15S)-hydroperoxy-(5Z,8Z,11Z,13E)-eicosatetraenoyl-gamma-aminobutanoate

Left to rightBalancedRhea 50180

N-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-L-alanine + O2 = N-(15S)-hydroperoxy-(5Z,8Z,11Z,13E)-eicosatetraenoyl-alanine

Left to rightBalancedRhea 50184

N-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-glycine + O2 = N-(15S)-hydroperoxy-(5Z,8Z,11Z,13E)-eicosatetraenoyl-glycine

Left to rightBalancedRhea 50188

L-seryl-[protein] + UDP-alpha-D-xylose = 3-O-(beta-D-xylosyl)-L-seryl-[protein] + UDP + H(+)

Direction not assertedBalance undeterminableRhea 50192

(5Z,8Z,11Z,14Z,17Z)-eicosapentaenoate + AH2 + O2 = (15S)-hydroxy-(5Z,8Z,11Z,13E,17Z)-eicosapentaenoate + A + H2O

Left to rightBalancedRhea 50196

(5Z,8Z,11Z,14Z,17Z)-eicosapentaenoate + AH2 + O2 = (18S)-hydroxy-(5Z,8Z,11Z,14Z,16E)-eicosapentaenoate + A + H2O

Left to rightBalancedRhea 50200

(18S)-hydroxy-(5Z,8Z,11Z,14Z,16E)-eicosapentaenoate + O2 = (5S)-hydroperoxy-(18S)-hydroxy-(6E,8Z,11Z,14Z,16E)-eicosapentaenoate

Left to rightBalancedRhea 50204

cortisol + NAD(+) = cortisone + NADH + H(+)

Left to rightBalancedRhea 50208

(13S)-hydroperoxy-(9Z,11E)-octadecadienoate = 11-hydroxy-(12S,13S)-epoxy-(9Z)-octadecenoate

Left to rightBalancedRhea 50212

(12S)-hydroperoxy-(5Z,8Z,10E,14Z)-eicosatetraenoate = (8S)-hydroxy-(11S,12S)-epoxy-(5Z,9E,14Z)-eicosatrienoate

Left to rightBalancedRhea 50216

(S)-demethyl-4-deoxygadusol = (R)-demethyl-4-deoxygadusol

Direction not assertedBalancedRhea 50220

3-(all-trans-hexaprenyl)benzene-1,2-diol + S-adenosyl-L-methionine = 2-methoxy-6-(all-trans-hexaprenyl)phenol + S-adenosyl-L-homocysteine + H(+)

Direction not assertedBalancedRhea 50224

resorcinol + FADH2 + O2 = benzene-1,2,4-triol + FAD + H2O + H(+)

Direction not assertedBalancedRhea 50228

heme b + 6 reduced [2Fe-2S]-[ferredoxin] + 3 O2 + 8 H(+) = biliverdin IXalpha + CO + Fe(2+) + 6 oxidized [2Fe-2S]-[ferredoxin] + 3 H2O

Direction not assertedBalance undeterminableRhea 50232

pregnenolone + reduced [NADPH--hemoprotein reductase] + O2 = 17alpha-hydroxypregnenolone + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Left to rightBalance undeterminableRhea 50236

[hyaluronan](n) = n 3-(4-deoxy-beta-D-gluc-4-enuronosyl)-N-acetyl-D-glucosamine + H2O

Direction not assertedBalance undeterminableRhea 50240

17alpha-hydroxypregnenolone + reduced [NADPH--hemoprotein reductase] + O2 = 3beta-hydroxyandrost-5-en-17-one + acetate + oxidized [NADPH--hemoprotein reductase] + H2O + 2 H(+)

Left to rightBalance undeterminableRhea 50244

D-ribose 5-phosphate + ATP + H(+) = ADP-D-ribose + diphosphate

ReversibleBalancedRhea 50248

an acyl-CoA + malonyl-CoA + H(+) = a 3-oxoacyl-CoA + CO2 + CoA

Direction not assertedBalance undeterminableRhea 50252

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