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ReactionsRhea and Human-GEM, by subsystem
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Reference

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Computational infrastructure for human biology, built on a provenance-aware knowledge graph. Findings retain their sources; research and simulation are the next layers.

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A reference for what the literature reports. Not medical advice.

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Index

Reactions

Reactions from Rhea and Human-GEM · Reach

reactions in the graph: 31,435

By source

Rhea18,558
Human-GEM12,877

Inferred

Reference data, not a finding. Evidence key

Filter reactions by equationSource

Reactions

22,301–22,350 of 31,435, by identifier

(5Z,8Z,11Z,14Z)-eicosatetraenoate + reduced [NADPH--hemoprotein reductase] + O2 = (14S,15R)-epoxy-(5Z,8Z,11Z)-eicosatrienoate + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)
Left to rightBalance undeterminableRhea 49856
(5Z,8Z,11Z,14Z)-eicosatetraenoate + reduced [NADPH--hemoprotein reductase] + O2 = (14R,15S)-epoxy-(5Z,8Z,11Z)-eicosatrienoate + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)
Left to rightBalance undeterminableRhea 49860
(+)-dehydrodiconiferyl acid + 2 a quinone + H2O = (+)-dehydrodiconiferyl acid carboxylate + 2 a quinol + H(+)
Direction not assertedBalance undeterminableRhea 49864
(+)-dehydrodiconiferyl acid + a quinone = (+)-dehydrodiconiferyl acid ketone + a quinol
Direction not assertedBalance undeterminableRhea 49868
(+)-dehydrodiconiferyl acid ketone + a quinone + H2O = (+)-dehydrodiconiferyl acid carboxylate + a quinol + H(+)
Direction not assertedBalance undeterminableRhea 49872
(5Z,8Z,11Z,14Z)-eicosatetraenoate + reduced [NADPH--hemoprotein reductase] + O2 = (11S,12R)-epoxy-(5Z,8Z,14Z)-eicosatrienoate + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Left to rightBalance undeterminableRhea 49876

(5Z,8Z,11Z,14Z)-eicosatetraenoate + reduced [NADPH--hemoprotein reductase] + O2 = (11R,12S)-epoxy-(5Z,8Z,14Z)-eicosatrienoate + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Left to rightBalance undeterminableRhea 49880

(5Z,8Z,11Z,14Z)-eicosatetraenoate + reduced [NADPH--hemoprotein reductase] + O2 = (8R,9S)-epoxy-(5Z,11Z,14Z)-eicosatrienoate + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Left to rightBalance undeterminableRhea 49884

(1R,6R)-1,4,5,5a,6,9-hexahydrophenazine-1,6-dicarboxylate + O2 = (1R,10aS)-1,4,10,10a-tetrahydrophenazine-1,6-dicarboxylate + H2O2

Direction not assertedBalancedRhea 49888

(1R,10aS)-1,4,10,10a-tetrahydrophenazine-1,6-dicarboxylate + O2 = (5aS)-5,5a-dihydrophenazine-1,6-dicarboxylate + H2O2

Direction not assertedBalancedRhea 49892

(5aS)-5,5a-dihydrophenazine-1,6-dicarboxylate = 5,10-dihydrophenazine-1,6-dicarboxylate

Direction not assertedBalancedRhea 49896

5,10-dihydrophenazine-1,6-dicarboxylate + O2 = phenazine-1,6-dicarboxylate + H2O2

Direction not assertedBalancedRhea 49900

(1R,6R)-1,4,5,5a,6,9-hexahydrophenazine-1,6-dicarboxylate + O2 + H(+) = (1R,10aS)-1,4,10,10a-tetrahydrophenazine-1-carboxylate + H2O2 + CO2

Direction not assertedBalancedRhea 49904

O-acetyl-(R)-carnitine(in) + (R)-carnitine(out) = O-acetyl-(R)-carnitine(out) + (R)-carnitine(in)

Direction not assertedBalancedTransportRhea 49908

O-propanoyl-(R)-carnitine(in) + (R)-carnitine(out) = O-propanoyl-(R)-carnitine(out) + (R)-carnitine(in)

Direction not assertedBalancedTransportRhea 49912

O-hexadecanoyl-(R)-carnitine(in) + (R)-carnitine(out) = O-hexadecanoyl-(R)-carnitine(out) + (R)-carnitine(in)

Direction not assertedBalancedTransportRhea 49916

O-octanoyl-(R)-carnitine(in) + (R)-carnitine(out) = O-octanoyl-(R)-carnitine(out) + (R)-carnitine(in)

Direction not assertedBalancedTransportRhea 49920

an O-acyl-(R)-carnitine(in) + (R)-carnitine(out) = an O-acyl-(R)-carnitine(out) + (R)-carnitine(in)

Direction not assertedBalance undeterminableTransportRhea 49924

(5Z,8Z,11Z,14Z)-eicosatetraenoate + reduced [NADPH--hemoprotein reductase] + O2 = (8S,9R)-epoxy-(5Z,11Z,14Z)-eicosatrienoate + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Left to rightBalance undeterminableRhea 49928

(3E,5Z)-octadienoyl-CoA = (2E,5Z)-octadienoyl-CoA

ReversibleBalancedRhea 49932

(5Z,8Z,11Z,14Z)-eicosatetraenoate + reduced [NADPH--hemoprotein reductase] + O2 = 5,6-epoxy-(8Z,11Z,14Z)-eicosatrienoate + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Left to rightBalance undeterminableRhea 49936

(1R,10aS)-1,4,10,10a-tetrahydrophenazine-1-carboxylate + O2 = (10aS)-10,10a-dihydrophenazine-1-carboxylate + H2O2

Direction not assertedBalancedRhea 49940

(1R,10aS)-1,4,10,10a-tetrahydrophenazine-1-carboxylate = (1R)-1,4,5,10-tetrahydrophenazine-1-carboxylate

Direction not assertedBalancedRhea 49944

(1R)-1,4,5,10-tetrahydrophenazine-1-carboxylate + O2 = (10aS)-10,10a-dihydrophenazine-1-carboxylate + H2O2

Direction not assertedBalancedRhea 49948

(10aS)-10,10a-dihydrophenazine-1-carboxylate = 5,10-dihydrophenazine 1-carboxylate

Direction not assertedBalancedRhea 49952

5,10-dihydrophenazine 1-carboxylate + O2 = phenazine-1-carboxylate + H2O2

Direction not assertedBalancedRhea 49956

(1R)-1,4,5,10-tetrahydrophenazine-1-carboxylate + O2 + H(+) = 5,10-dihydrophenazine + H2O2 + CO2

Direction not assertedBalancedRhea 49960

5,10-dihydrophenazine + O2 = phenazine + H2O2

Direction not assertedBalancedRhea 49964

(5Z,8Z,11Z,14Z)-eicosatetraenoate + reduced [NADPH--hemoprotein reductase] + O2 = 17-hydroxy-(5Z,8Z,11Z,14Z)-eicosatetraenoate + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Left to rightBalance undeterminableRhea 49968

(5Z,8Z,11Z,14Z)-eicosatetraenoate + reduced [NADPH--hemoprotein reductase] + O2 = 16-hydroxy-(5Z,8Z,11Z,14Z)-eicosatetraenoate + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Left to rightBalance undeterminableRhea 49972

butanoyl-CoA + H2O = S-butanoyl-4'-phosphopantetheine + adenosine 3',5'-bisphosphate + 2 H(+)

Left to rightBalancedRhea 49976

hexanoyl-CoA + H2O = hexanoyl-4'-phosphopantetheine + adenosine 3',5'-bisphosphate + 2 H(+)

Left to rightBalancedRhea 49980

jasmonate + NADPH + O2 + H(+) = (1R,2R)-12-hydroxyjasmonate + NADP(+) + H2O

Direction not assertedBalancedRhea 49984

acetone + NADPH + O2 + H(+) = methyl acetate + NADP(+) + H2O

Direction not assertedBalancedRhea 49988

propane + NADH + O2 + H(+) = propan-2-ol + NAD(+) + H2O

Direction not assertedBalancedRhea 49992

cholest-4-en-3-one + 6 reduced [2Fe-2S]-[ferredoxin] + 3 O2 + 5 H(+) = (25R)-3-oxocholest-4-en-26-oate + 6 oxidized [2Fe-2S]-[ferredoxin] + 4 H2O

Direction not assertedBalance undeterminableRhea 49996

butane + NADH + O2 + H(+) = butan-1-ol + NAD(+) + H2O

Direction not assertedBalancedRhea 50000

tetracycline + NADPH + O2 + H(+) = 11a-hydroxytetracycline + NADP(+) + H2O

Direction not assertedBalancedRhea 50004

6-methylpretetramide + NADPH + O2 + 2 H(+) = 4-hydroxy-6-methylpretetramide + NADP(+) + H2O

Direction not assertedBalancedRhea 50008

tert-butanol + NADPH + O2 + H(+) = 2-methylpropane-1,2-diol + NADP(+) + H2O

Direction not assertedBalancedRhea 50012

octanoyl-CoA + H2O = S-octanoyl-4'-phosphopantetheine + adenosine 3',5'-bisphosphate + 2 H(+)

Left to rightBalancedRhea 50016

decanoyl-CoA + H2O = decanoyl-4'-phosphopantetheine + adenosine 3',5'-bisphosphate + 2 H(+)

Left to rightBalancedRhea 50020

dodecanoyl-CoA + H2O = S-dodecanoyl-4'-phosphopantetheine + adenosine 3',5'-bisphosphate + 2 H(+)

Left to rightBalancedRhea 50024

tetradecanoyl-CoA + H2O = tetradecanoyl-4'-phosphopantetheine + adenosine 3',5'-bisphosphate + 2 H(+)

Left to rightBalancedRhea 50028

hexadecanoyl-CoA + H2O = S-hexadecanoyl-4'-phosphopantetheine + adenosine 3',5'-bisphosphate + 2 H(+)

Left to rightBalancedRhea 50032

choloyl-CoA + H2O = S-choloyl-4'-phosphopantetheine + adenosine 3',5'-bisphosphate + 2 H(+)

Left to rightBalancedRhea 50036

3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-oyl-CoA + H2O = 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-oyl-4'-phosphopantetheine + adenosine 3',5'-bisphosphate + 2 H(+)

Left to rightBalancedRhea 50040

an acyl-CoA + H2O = an acyl-4'-phosphopantetheine + adenosine 3',5'-bisphosphate + 2 H(+)

Left to rightBalance undeterminableRhea 50044

cholate(in) + ATP + H2O = cholate(out) + ADP + phosphate + H(+)

Left to rightBalancedTransportRhea 50048

taurocholate(in) + ATP + H2O = taurocholate(out) + ADP + phosphate + H(+)

Left to rightBalancedTransportRhea 50052

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