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CompoundsSubstances with curated findings
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ProteinsTransporters and enzymes
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ReactionsRhea and Human-GEM, by subsystem
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PathwaysReactions grouped under one name
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AnatomyTissues, by what is expressed there
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MaterialsSubstances that are not one molecule
AssessmentsRegulatory determinations, transcribed
DiseasesFeatures, genes, and where each sits

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Reference

Evidence

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Proteins
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Computational infrastructure for human biology, built on a provenance-aware knowledge graph. Findings retain their sources; research and simulation are the next layers.

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A reference for what the literature reports. Not medical advice.

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Index

Reactions

Reactions from Rhea and Human-GEM · Reach

reactions in the graph: 31,435

By source

Rhea18,558
Human-GEM12,877

Inferred

Reference data, not a finding. Evidence key

Filter reactions by equationSource

Reactions

22,251–22,300 of 31,435, by identifier

Fe-coproporphyrin III + 2 H(+) = coproporphyrin III + Fe(2+)
Direction not assertedBalancedRhea 49572
GTP + AH2 + S-adenosyl-L-methionine = (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate + 5'-deoxyadenosine + L-methionine + A + H(+)
Direction not assertedBalancedRhea 49576
(8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate = cyclic pyranopterin phosphate + diphosphate
Direction not assertedBalancedRhea 49580
D-erythrulose 1-phosphate = L-erythrulose 1-phosphate
Direction not assertedBalancedRhea 49584
L-erythrulose 1-phosphate = D-erythrulose 4-phosphate
Direction not assertedBalancedRhea 49588
2-hydroxyisobutanoyl-CoA = (3S)-3-hydroxybutanoyl-CoA
Direction not assertedBalancedRhea 49592
an N-acylsphing-4-enine + UDP-alpha-D-galactose = N-acyl-D-galactosylsphing-4-enine + UDP + H(+)

Direction not assertedBalance undeterminableRhea 49596

octanedioate + ATP + CoA = octanedioyl-CoA + AMP + diphosphate

Direction not assertedBalancedRhea 49600

2-glutathionyl-2-methylbut-3-en-1-ol + NAD(+) = 2-glutathionyl-2-methylbut-3-enal + NADH + H(+)

Direction not assertedBalancedRhea 49604

2-glutathionyl-2-methylbut-3-enal + NAD(+) + H2O = 2-glutathionyl-2-methylbut-3-enoate + NADH + 2 H(+)

Direction not assertedBalancedRhea 49608

(R)-2-hydroxyglutarate + NAD(+) = 2-oxoglutarate + NADH + H(+)

Direction not assertedBalancedRhea 49612

2-hydroxy-2-methylpropanal + NAD(+) + H2O = 2-hydroxy-2-methylpropanoate + NADH + 2 H(+)

Direction not assertedBalancedRhea 49616

D-erythritol 1-phosphate + NADP(+) = D-erythrulose 1-phosphate + NADPH + H(+)

Direction not assertedBalancedRhea 49620

erythritol + ATP = D-erythritol 1-phosphate + ADP + H(+)

Direction not assertedBalancedRhea 49624

3 malonyl-CoA + acetyl-CoA + 2 S-adenosyl-L-methionine = 3,5-dimethylorsellinate + 2 S-adenosyl-L-homocysteine + 3 CO2 + 4 CoA

Direction not assertedBalancedRhea 49628

3,5-dimethylorsellinate + (2E,6E)-farnesyl diphosphate = (3R)-3-farnesyl-6-hydroxy-2,3,5-trimethyl-4-oxocyclohexa-1,5-diene-1-carboxylate + diphosphate + H(+)

Direction not assertedBalancedRhea 49632

methylglyoxal + O2 + H2O = pyruvate + H2O2 + H(+)

Direction not assertedBalancedRhea 49636

protoviolaceinate + NADH + O2 + H(+) = violaceinate + NAD(+) + H2O

Direction not assertedBalancedRhea 49652

protodeoxyviolaceinate + NADH + O2 + H(+) = deoxyviolaceinate + NAD(+) + H2O

Direction not assertedBalancedRhea 49668

L-methionyl(47)-[F-actin] + NADPH + O2 + H(+) = L-methionyl(47)-(R)-S-oxide-[F-actin] + NADP(+) + H2O

Direction not assertedBalance undeterminableRhea 49676

resorcinol + NADH + O2 + H(+) = benzene-1,2,4-triol + NAD(+) + H2O

Direction not assertedBalancedRhea 49684

nocardicin G + S-adenosyl-L-methionine = isonocardicin C + S-methyl-5'-thioadenosine + H(+)

Direction not assertedBalancedRhea 49708

3-hydroxy-4-methylanthranilyl-[aryl-carrier protein] + NADH + O2 + H(+) = 3,5-dihydroxy-4-methylanthranilyl-[aryl-carrier protein] + NAD(+) + H2O

Direction not assertedBalance undeterminableRhea 49716

protoviolaceinate + NADH + 2 O2 + 2 H(+) = violacein + CO2 + NAD(+) + 2 H2O

Direction not assertedBalancedRhea 49720

protoviolaceinate + NADPH + 2 O2 + 2 H(+) = violacein + CO2 + NADP(+) + 2 H2O

Direction not assertedBalancedRhea 49728

violaceinate + O2 + H(+) = violacein + CO2 + H2O

Direction not assertedBalancedRhea 49732

protodeoxyviolaceinate + NADH + 2 O2 + 2 H(+) = deoxyviolacein + CO2 + NAD(+) + 2 H2O

Direction not assertedBalancedRhea 49736

protodeoxyviolaceinate + NADPH + 2 O2 + 2 H(+) = deoxyviolacein + CO2 + NADP(+) + 2 H2O

Direction not assertedBalancedRhea 49740

deoxyviolaceinate + O2 + H(+) = deoxyviolacein + CO2 + H2O

Direction not assertedBalancedRhea 49744

protodeoxyviolaceinate + NADPH + 2 O2 + 2 H(+) = proviolacein + CO2 + NADP(+) + 2 H2O

Direction not assertedBalancedRhea 49748

protodeoxyviolaceinate + NADH + 2 O2 + 2 H(+) = proviolacein + CO2 + NAD(+) + 2 H2O

Direction not assertedBalancedRhea 49752

protoviolaceinate + O2 + H(+) = proviolacein + CO2 + H2O

Direction not assertedBalancedRhea 49756

EDTA + FMNH2 + O2 = ethylenediaminetriacetate + FMN + glyoxylate + H2O + 2 H(+)

Direction not assertedBalancedRhea 49760

ethylenediaminetriacetate + FMNH2 + O2 = ethylenediaminediacetate + FMN + glyoxylate + H2O + H(+)

Direction not assertedBalancedRhea 49764

hexacosanoyl-CoA + glycine = N-hexacosanoylglycine + CoA + H(+)

Left to rightBalancedRhea 49772

docosanoyl-CoA + glycine = N-docosanoylglycine + CoA + H(+)

Left to rightBalancedRhea 49780

chenodeoxycholoyl-CoA + taurine = taurochenodeoxycholate + CoA + H(+)

Left to rightBalancedRhea 49784

chenodeoxycholoyl-CoA + glycine = glycochenodeoxycholate + CoA + H(+)

Left to rightBalancedRhea 49788

eicosanoyl-CoA + glycine = N-eicosanoylglycinate + CoA + H(+)

Left to rightBalancedRhea 49792

an N-(fatty acyl)-glycine + H2O = a fatty acid + glycine

Direction not assertedBalance undeterminableRhea 49796

2-methylpropan-1-amine + FMNH2 + O2 = N-(2-methylpropyl)hydroxylamine + FMN + H2O + 2 H(+)

Direction not assertedBalancedRhea 49804

butan-1-ol + a quinone = butanal + a quinol

Direction not assertedBalance undeterminableRhea 49808

hydrazine + 3 Fe(III)-[cytochrome c] + H2O = nitric oxide + 3 Fe(II)-[cytochrome c] + NH4(+) + 2 H(+)

Direction not assertedBalance undeterminableRhea 49816

(5E)-tetradecenoyl-CoA + oxidized [electron-transfer flavoprotein] + H(+) = (2E,5E)-tetradecadienoyl-CoA + reduced [electron-transfer flavoprotein]

Left to rightBalance undeterminableRhea 49828

a fatty aldehyde + NAD(+) + H2O = a fatty acid + NADH + 2 H(+)

Direction not assertedBalance undeterminableRhea 49832

(5E)-tetradecenoyl-CoA + (R)-carnitine = (5E)-tetradecenoyl-(R)-carnitine + CoA

Direction not assertedBalancedRhea 49836

(-)-dehydrodiconiferyl acid + 2 a quinone + H2O = (-)-dehydrodiconiferyl acid carboxylate + 2 a quinol + H(+)

Direction not assertedBalance undeterminableRhea 49840

(-)-dehydrodiconiferyl acid + a quinone = (-)-dehydrodiconiferyl acid ketone + a quinol

Direction not assertedBalance undeterminableRhea 49844

(-)-dehydrodiconiferyl acid ketone + a quinone + H2O = (-)-dehydrodiconiferyl acid carboxylate + a quinol + H(+)

Direction not assertedBalance undeterminableRhea 49848

(3E)-octenoyl-CoA = (2E)-octenoyl-CoA

Left to rightBalancedRhea 49852

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