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CompoundsSubstances with curated findings
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ReactionsRhea and Human-GEM, by subsystem
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Reference

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Computational infrastructure for human biology, built on a provenance-aware knowledge graph. Findings retain their sources; research and simulation are the next layers.

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A reference for what the literature reports. Not medical advice.

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Index

Reactions

Reactions from Rhea and Human-GEM · Reach

reactions in the graph: 31,435

By source

Rhea18,558
Human-GEM12,877

Inferred

Reference data, not a finding. Evidence key

Filter reactions by equationSource

Reactions

21,951–22,000 of 31,435, by identifier

a 1,2-saturated fatty acid + H2O2 = a 2-hydroxy fatty acid + H2O
Direction not assertedBalance undeterminableRhea 48360
a neolactoside nLc6Cer + GDP-beta-L-fucose = beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosaminyl-(1->3)-beta-D-galactosyl-(1->4)-[alpha-L-fucosyl-(1->3)]-N-acetyl-beta-D-glucosaminyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1')-ceramide + GDP + H(+)
Left to rightBalance undeterminableRhea 48364
a neolactoside nLc6Cer + GDP-beta-L-fucose = beta-D-Gal-(1->4)-[alpha-L-Fuc-(1->3)]-beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-beta-D-Glc-(1<->1')-Cer + GDP + H(+)
Left to rightBalance undeterminableRhea 48368
a 1,2-diacyl-3-O-[alpha-D-galactosyl-(1->6)-beta-D-galactosyl]-sn-glycerol + H2O = acyl-3-O-[alpha-D-galactosyl-(1->6)-beta-D-galactosyl]-sn-glycerol + a fatty acid + H(+)
Left to rightBalance undeterminableRhea 48372
a neolactoside nLc4Cer + GDP-beta-L-fucose = a neolactoside III(3)-alpha-Fuc-nLc4Cer + GDP + H(+)
Left to rightBalance undeterminableRhea 48376
alpha-D-galactosyl-(1->3)-beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosaminyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1')-ceramide + GDP-beta-L-fucose = a neolactoside IV(3)-alpha-Gal,III(3)-alpha-Fuc-nLc4Cer + GDP + H(+)

Left to rightBalance undeterminableRhea 48380

a 2,3-saturated fatty acid + H2O2 = a 3-hydroxy fatty acid + H2O

Direction not assertedBalance undeterminableRhea 48384

alpha-N-glycoloylneuraminosyl-(2->3)-beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosaminyl-(1->3)-beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosaminyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1')-ceramide + GDP-beta-L-fucose = alpha-N-glycoloylneuraminosyl-(2->3)-beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosaminyl-(1->3)-beta-D-galactosyl-(1->4)-[alpha-L-fucosyl-(1->3)]-N-acetyl-beta-D-glucosaminyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1')-ceramide + GDP + H(+)

Left to rightBalance undeterminableRhea 48388

a neolactoside IV(3)-alpha-NeuAc-nLc4Cer + GDP-beta-L-fucose = a neolactoside IV(3)-alpha-NeuNAc,III(3)-alpha-Fuc-nLc4Cer + GDP + H(+)

Left to rightBalance undeterminableRhea 48392

(3,5-dichloro-2,4,6-trihydroxyphenyl)hexan-1-one + S-adenosyl-L-methionine = 1-(3,5-dichloro-2,6-dihydroxy-4-methoxyphenyl)hexan-1-one + S-adenosyl-L-homocysteine + H(+)

Direction not assertedBalancedRhea 48396

L-prolyl-[hypoxia-inducible factor alpha subunit] + 2-oxoglutarate + O2 = trans-4-hydroxy-L-prolyl-[hypoxia-inducible factor alpha subunit] + succinate + CO2

Direction not assertedBalance undeterminableRhea 48400

apo-[aryl-carrier protein] + CoA = holo-[aryl-carrier protein] + adenosine 3',5'-bisphosphate + H(+)

Direction not assertedBalance undeterminableRhea 48404

a globoside IV3GalNAc-Gb4Cer + H2O = a globoside Gb4Cer + N-acetyl-alpha-D-galactosamine

Left to rightBalance undeterminableRhea 48412

a ganglioside GA2 (d18:1(4E)) + CMP-N-acetyl-beta-neuraminate = a ganglioside GM2 (d18:1(4E)) + CMP + H(+)

Direction not assertedBalance undeterminableRhea 48416

a ganglioside GA1 (d18:1(4E)) + CMP-N-acetyl-beta-neuraminate = a ganglioside GM1 (d18:1(4E)) + CMP + H(+)

Direction not assertedBalance undeterminableRhea 48420

dUMP + (6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + H2O = 5-hydroxymethyl-dUMP + (6S)-5,6,7,8-tetrahydrofolate

Direction not assertedBalancedRhea 48424

1-(9Z,12Z-octadecadienoyl)-glycerol + H2O = (9Z,12Z)-octadecadienoate + glycerol + H(+)

Left to rightBalancedRhea 48428

N(6)-D-ribulosyl-L-lysyl-[protein] + ATP = N(6)-(3-O-phospho-D-ribulosyl)-L-lysyl-[protein] + ADP + H(+)

Left to rightBalance undeterminableRhea 48432

pentanoate ester + H2O = pentanoate + an aliphatic alcohol + H(+)

Direction not assertedBalance undeterminableRhea 48436

long chain 1,2-diacyl-3-O-[alpha-D-galactosyl-(1->6)-beta-D-galactosyl]-sn-glycerol + H2O = long chain 2-acyl-3-O-[alpha-D-galactosyl-(1->6)-beta-D-galactosyl]-sn-glycerol + a fatty acid + H(+)

Direction not assertedBalance undeterminableRhea 48440

long chain 1,2-diacyl-3-O-beta-D-galactosyl-sn-glycerol + H2O = long chain 2-acyl-3-O-beta-D-galactosyl-sn-glycerol + a fatty acid + H(+)

Direction not assertedBalance undeterminableRhea 48444

a ganglioside GA2 + H2O = N-acetyl-beta-D-galactosamine + a beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1)-ceramide

Direction not assertedBalance undeterminableRhea 48448

a ganglioside GA2 (d18:1(4E)) + H2O = N-acetyl-beta-D-galactosamine + a beta-D-Gal-(1->4)-beta-D-Glc-(1<->1)-Cer(d18:1(4E))

Direction not assertedBalance undeterminableRhea 48452

1,2-dioctanoyl-3-O-beta-D-galactosyl-sn-glycerol + H2O = 2-octanoyl-3-O-beta-D-galactosyl-sn-glycerol + octanoate + H(+)

Direction not assertedBalancedRhea 48456

1,2-dioctanoyl-3-O-[alpha-D-galactosyl-(1->6)-beta-D-galactosyl]-sn-glycerol + H2O = 2-octanoyl-3-O-[alpha-D-galactosyl-(1->6)-beta-D-galactosyl]-sn-glycerol + octanoate + H(+)

Direction not assertedBalancedRhea 48460

a ganglioside GM1b + H2O = a ganglioside GA1 + N-acetylneuraminate

Direction not assertedBalance undeterminableRhea 48464

a ganglioside GM1b (d18:1(4E)) + H2O = a ganglioside GA1 (d18:1(4E)) + N-acetylneuraminate

Direction not assertedBalance undeterminableRhea 48468

a ganglioside GT1a + H2O = a ganglioside GD1a + N-acetylneuraminate

Direction not assertedBalance undeterminableRhea 48472

a ganglioside GT1a (d18:1(4E)) + H2O = a ganglioside GD1a (d18:1(4E)) + N-acetylneuraminate

Direction not assertedBalance undeterminableRhea 48476

1,2-di-(9Z-octadecenoyl)-sn-glycerol + UDP-alpha-D-galactose = 1,2-di-(9Z-octadecenoyl)-3-beta-D-galactosyl-sn-glycerol + UDP + H(+)

Direction not assertedBalancedRhea 48480

a propanoate ester + H2O = an aliphatic alcohol + propanoate + H(+)

Direction not assertedBalance undeterminableRhea 48484

all-trans-retinol--[retinol-binding protein] + NAD(+) = all-trans-retinal--[retinol-binding protein] + NADH + H(+)

Direction not assertedBalance undeterminableRhea 48488

1,2-di-(9Z,12Z-octadecadienoyl)-sn-glycerol + UDP-alpha-D-galactose = 1,2-di-(9Z,12Z-octadecadienoyl)-3-beta-D-galactosyl-sn-glycerol + UDP + H(+)

Direction not assertedBalancedRhea 48492

1-(9Z-octadecenoyl)-2-hexadecanoyl-sn-glycerol + UDP-alpha-D-galactose = 1-(9Z-octadecenoyl)-2-hexadecanoyl-3-beta-D-galactosyl-sn-glycerol + UDP + H(+)

Direction not assertedBalancedRhea 48496

octanoylglycerol + H2O = octanoate + glycerol + H(+)

Direction not assertedBalancedRhea 48500

D-glycero-D-manno-heptose 1,7-bisphosphate + H2O = D-glycero-D-manno-heptose 1-phosphate + phosphate

Direction not assertedBalancedRhea 48504

cholate + NADP(+) = 3alpha,12alpha-dihydroxy-7-oxo-5beta-cholanate + NADPH + H(+)

Direction not assertedBalancedRhea 48508

phosphinate(out) + ATP + H2O = phosphinate(in) + ADP + phosphate + H(+)

Direction not assertedBalancedTransportRhea 48512

1,2-didodecanoyl-3-O-[alpha-D-galactosyl-(1->6)-beta-D-galactosyl]-sn-glycerol + H2O = dodecanoyl-3-O-[alpha-D-galactosyl-(1->6)-beta-D-galactosyl]-sn-glycerol + dodecanoate + H(+)

Left to rightBalancedRhea 48516

[protein]-C-terminal S-[(2E,6E)-farnesyl]-L-cysteine methyl ester + H2O = [protein]-C-terminal S-[(2E,6E)-farnesyl]-L-cysteine + methanol + H(+)

Direction not assertedBalance undeterminableRhea 48520

a ganglioside GP1c + H2O = a ganglioside GQ1c + N-acetylneuraminate

Direction not assertedBalance undeterminableRhea 48524

a ganglioside GP1c (d18:1(4E)) + H2O = a ganglioside GQ1c (d18:1(4E)) + N-acetylneuraminate

Direction not assertedBalance undeterminableRhea 48528

a ganglioside GQ1c (d18:1(4E)) + H2O = a ganglioside GT1c (d18:1(4E)) + N-acetylneuraminate

Direction not assertedBalance undeterminableRhea 48532

1-beta-D-galactosyl-2,3-didodecanoyl-sn-glycerol + H2O = 1-beta-D-galactosyl-dodecanoyl-sn-glycerol + dodecanoate + H(+)

Left to rightBalancedRhea 48536

1,2-didodecanoyl-3-beta-D-galactosyl-sn-glycerol + H2O = dodecanoyl-3-beta-D-galactosyl-sn-glycerol + dodecanoate + H(+)

Left to rightBalancedRhea 48540

[phosphatase 2A protein]-C-terminal L-leucine + S-adenosyl-L-methionine = [phosphatase 2A protein]-C-terminal L-leucine methyl ester + S-adenosyl-L-homocysteine

Direction not assertedBalance undeterminableRhea 48544

[phosphatase 2A protein]-C-terminal L-leucine methyl ester + H2O = [phosphatase 2A protein]-C-terminal L-leucine + methanol + H(+)

Direction not assertedBalance undeterminableRhea 48548

1-(9S,13S-12-oxo-10,15Z-phytodienoyl)-2-(7Z,10Z,13Z)-hexadecatrienoyl-3-O-(beta-D-galactosyl)-sn-glycerol + H2O = 2-(7Z,10Z,13Z)-hexadecatrienoyl-3-O-(beta-D-galactosyl)-sn-glycerol + (9S,13S,15Z)-12-oxophyto-10,15-dienoate + H(+)

Direction not assertedBalancedRhea 48552

5-phospho-alpha-D-ribose 1-diphosphate + 4-hydroxybenzoate + H(+) = 4-(beta-D-ribofuranosyl)phenol 5'-phosphate + CO2 + diphosphate

Direction not assertedBalancedRhea 48556

N(6)-(dimethylallyl)adenosine 5'-phosphate + H2O = N(6)-dimethylallyladenine + D-ribose 5-phosphate

Direction not assertedBalancedRhea 48560

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