Skip to content

Reference

Evidence

CompoundsSubstances with curated findings
OutcomesMeasured endpoints
ProteinsTransporters and enzymes
InteractionsPairs that share biology
PapersEvery paper a finding cites
ArticlesReadings of the evidence

Chemistry

ReactionsRhea and Human-GEM, by subsystem
ReachWhat a compound can become

Reference layer

PathwaysReactions grouped under one name
ProcessesWhat proteins are annotated as doing
AnatomyTissues, by what is expressed there
Cell typesCells, by what is expressed there
OrganismsSpecies a compound is prepared from
MaterialsSubstances that are not one molecule
AssessmentsRegulatory determinations, transcribed
DiseasesFeatures, genes, and where each sits

Atlas Graph Twin Access

Search the graph

Reference

Evidence

Compounds
Outcomes
Proteins
Interactions
Papers
Articles

Chemistry

Reactions
Reach

Reference layer

Pathways
Processes
Anatomy
Cell types
Organisms
Materials
Assessments
Diseases

Atlas Graph Twin Access

Loading the page.

Catalyst

Computational infrastructure for human biology, built on a provenance-aware knowledge graph. Findings retain their sources; research and simulation are the next layers.

The graph

Compounds
Outcomes
Proteins
Atlas
Interactions
Papers
Articles
Graph
Search

Reference layer

Pathways
Processes
Anatomy
Cell types
Organisms
Materials
Assessments
Diseases
Reactions
Reach

How it works

Mission
Method
Twin
How to read the evidence
Sources and licences

Build on it

Access
In your assistant
For agents
Query the graph
Bulk export

A reference for what the literature reports. Not medical advice.

© 2026 CatalystPrivacy TermsReference data under the licences listed on the attribution page.

Index

Reactions

Reactions from Rhea and Human-GEM · Reach

reactions in the graph: 31,435

By source

Rhea18,558
Human-GEM12,877

Inferred

Reference data, not a finding. Evidence key

Filter reactions by equationSource

Reactions

21,901–21,950 of 31,435, by identifier

pheophorbide a + 2 reduced [2Fe-2S]-[ferredoxin] + O2 + 3 H(+) = epoxypheophorbide a + 2 oxidized [2Fe-2S]-[ferredoxin] + H2O
Direction not assertedBalance undeterminableRhea 48160
epoxypheophorbide a + H2O = red chlorophyll catabolite + H(+)
Direction not assertedBalancedRhea 48164
N-acetyl-alpha-neuraminyl-(2->8)-N-acetyl-alpha-neuraminyl-(2->3)-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1)-N-(octadecanoyl)-sphing-4-enine + H2O = N-acetyl-alpha-neuraminyl-(2->3)-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1)-N-(octadecanoyl)-sphing-4-enine + N-acetylneuraminate
Direction not assertedBalancedRhea 48168
a ganglioside GM2 + H2O = a ganglioside GA2 + N-acetylneuraminate
Left to rightBalance undeterminableRhea 48172
decanoyl-CoA + oxidized [electron-transfer flavoprotein] + H(+) = (2E)-decenoyl-CoA + reduced [electron-transfer flavoprotein]
Left to rightBalance undeterminableRhea 48176
octanoyl-CoA + oxidized [electron-transfer flavoprotein] + H(+) = (2E)-octenoyl-CoA + reduced [electron-transfer flavoprotein]

→ Left to right

Balance undeterminable

Rhea 48180

(4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-CoA + oxidized [electron-transfer flavoprotein] + H(+) = (2E,4Z,7Z,10Z,13Z,16Z,19Z)-docosaheptaenoyl-CoA + reduced [electron-transfer flavoprotein]

Direction not assertedBalance undeterminableRhea 48184

(9Z,12Z)-octadecadienoyl-CoA + oxidized [electron-transfer flavoprotein] + H(+) = (2E,9Z,12Z)-octadecatrienoyl-CoA + reduced [electron-transfer flavoprotein]

Left to rightBalance undeterminableRhea 48188

(9E)-octadecenoyl-CoA + oxidized [electron-transfer flavoprotein] + H(+) = (2E,9E)-octadecadienoyl-CoA + reduced [electron-transfer flavoprotein]

Left to rightBalance undeterminableRhea 48192

heptadecanoyl-CoA + oxidized [electron-transfer flavoprotein] + H(+) = trans-2-heptadecenoyl-CoA + reduced [electron-transfer flavoprotein]

Left to rightBalance undeterminableRhea 48196

undecanoyl-CoA + oxidized [electron-transfer flavoprotein] + H(+) = trans-2-undecenoyl-CoA + reduced [electron-transfer flavoprotein]

Left to rightBalance undeterminableRhea 48200

pentadecanoyl-CoA + oxidized [electron-transfer flavoprotein] + H(+) = (2E)-pentadecenoyl-CoA + reduced [electron-transfer flavoprotein]

Left to rightBalance undeterminableRhea 48204

nonanoyl-CoA + oxidized [electron-transfer flavoprotein] + H(+) = (2E)-nonenoyl-CoA + reduced [electron-transfer flavoprotein]

Left to rightBalance undeterminableRhea 48208

a neolactoside IV(3)-alpha-GalNAc,IV(2)-alpha-Fuc-nLc4Cer(d18:1(4E)) + H2O = a neolactoside IV(2)-alpha-Fuc-nLc4Cer(d18:1(4E)) + N-acetyl-alpha-D-galactosamine

Left to rightBalance undeterminableRhea 48212

hexacosanoyl-CoA + oxidized [electron-transfer flavoprotein] + H(+) = (2E)-hexacosenoyl-CoA + reduced [electron-transfer flavoprotein]

Direction not assertedBalance undeterminableRhea 48216

tricosanoyl-CoA + oxidized [electron-transfer flavoprotein] + H(+) = (2E)-tricosenoyl-CoA + reduced [electron-transfer flavoprotein]

Direction not assertedBalance undeterminableRhea 48220

a neolactoside IV(2)-alpha-Fuc-nLc4Cer(d18:1(4E)) + H2O = a neolactoside nLc4Cer(d18:1(4E)) + L-fucose

Left to rightBalance undeterminableRhea 48224

N-terminal S-1,2-diacyl-sn-glyceryl-L-cysteinyl-[lipoprotein] + a glycerophospholipid = N-acyl-S-1,2-diacyl-sn-glyceryl-L-cysteinyl-[lipoprotein] + a 2-acyl-sn-glycero-3-phospholipid + H(+)

Direction not assertedBalance undeterminableRhea 48228

L-glutamate 5-semialdehyde + acetyl-CoA = N-acetyl-L-glutamate 5-semialdehyde + CoA + H(+)

Direction not assertedBalancedRhea 48232

2 2-acetylphloroglucinol = 2,4-diacetylphloroglucinol + 1,3,5-trihydroxybenzene + H(+)

Direction not assertedBalancedRhea 48236

a ganglioside GD1b + CMP-N-acetyl-beta-neuraminate = a ganglioside GT1b + CMP + H(+)

Left to rightBalance undeterminableRhea 48240

a ganglioside GA1 + CMP-N-acetyl-beta-neuraminate = a ganglioside GM1b + CMP + H(+)

Left to rightBalance undeterminableRhea 48244

ganglioside GM1 (d18:1(4E)/18:0) + CMP-N-acetyl-beta-neuraminate = ganglioside GD1a (18:1(4E)/18:0) + CMP + H(+)

Left to rightBalancedRhea 48248

a ganglioside GD2 + UDP-alpha-D-galactose = a ganglioside GD1b + UDP + H(+)

Direction not assertedBalance undeterminableRhea 48252

(2S)-2-methylbutanoyl-CoA + oxidized [electron-transfer flavoprotein] + H(+) = (2E)-2-methylbut-2-enoyl-CoA + reduced [electron-transfer flavoprotein]

Left to rightBalance undeterminableRhea 48256

a ganglioside GM1 + CMP-N-acetyl-beta-neuraminate = a ganglioside GD1a + CMP + H(+)

Left to rightBalance undeterminableRhea 48260

S-sulfosulfanyl-L-cysteinyl-[SoxY protein] + H2O = S-sulfanyl-L-cysteinyl-[SoxY protein] + sulfate + H(+)

Direction not assertedBalance undeterminableRhea 48264

4',4'-dihydroxyechinenone = canthaxanthin + H2O

Direction not assertedBalancedRhea 48268

2-methylhexanoyl-CoA + oxidized [electron-transfer flavoprotein] + H(+) = 2-methylhexenoyl-CoA + reduced [electron-transfer flavoprotein]

Left to rightBalance undeterminableRhea 48272

N-acetyl-beta-D-galactosaminyl-(1->4)-beta-D-3-sulfogalactosyl-(1->4)-beta-D-glucosyl-(1<->1')-ceramide + H2O = a beta-D-3-sulfogalactosyl-(1->4)-beta-D-glucosyl-(1<->1')-ceramide + N-acetyl-beta-D-galactosamine

Left to rightBalance undeterminableRhea 48276

a ganglioside GM2 + UDP-alpha-D-galactose = a ganglioside GM1 + UDP + H(+)

Left to rightBalance undeterminableRhea 48280

a globoside Gb4Cer (d18:1(4E)) + UDP-alpha-D-galactose = a globoside NOR1 (d18:1(4E)) + UDP + H(+)

Direction not assertedBalance undeterminableRhea 48284

a ganglioside GM3 + CMP-N-acetyl-beta-neuraminate = a ganglioside GD3 + CMP + H(+)

Left to rightBalance undeterminableRhea 48288

a ganglioside GM1 + GDP-beta-L-fucose = a ganglioside Fuc-GM1 + GDP + H(+)

Left to rightBalance undeterminableRhea 48292

prostaglandin E2 1-glyceryl ester + H2O = prostaglandin E2 + glycerol + H(+)

Left to rightBalancedRhea 48296

prostaglandin F2alpha 1-glyceryl ester + H2O = prostaglandin F2alpha + glycerol + H(+)

Left to rightBalancedRhea 48300

a neolactoside nLc4Cer(d18:1(4E)) + GDP-beta-L-fucose = a neolactoside IV(2)-alpha-Fuc-nLc4Cer(d18:1(4E)) + GDP + H(+)

Left to rightBalance undeterminableRhea 48304

2,3-epoxy-2,3-dihydrobenzoyl-CoA + 2 H2O = (3Z)-6-oxohex-3-enoyl-CoA + formate + H(+)

Direction not assertedBalancedRhea 48308

benzoyl-CoA + NADPH + O2 + H(+) = 2,3-epoxy-2,3-dihydrobenzoyl-CoA + NADP(+) + H2O

Direction not assertedBalancedRhea 48312

a ganglioside GM1b + CMP-N-acetyl-beta-neuraminate = a ganglioside GD1alpha + CMP + H(+)

Direction not assertedBalance undeterminableRhea 48316

a ganglioside GA1 + GDP-beta-L-fucose = a ganglioside Fuc-GA1 + GDP + H(+)

Left to rightBalance undeterminableRhea 48320

a ganglioside GD1b + GDP-beta-L-fucose = a ganglioside Fuc-GD1b + GDP + H(+)

Left to rightBalance undeterminableRhea 48324

a beta-D-Gal-(1->3)-beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-beta-D-Glc-(1<->1')-Cer(d18:1(4E)) + GDP-beta-L-fucose = a III(4)-a-Fuc-Lc4Cer(d18:1(4E)) + GDP + H(+)

Left to rightBalance undeterminableRhea 48328

a neolactoside nLc4Cer(d18:1(4E)) + GDP-beta-L-fucose = a neolactoside III(3)-alpha-Fuc-nLc4Cer(d18:1(4E)) + GDP + H(+)

Left to rightBalance undeterminableRhea 48332

a neolactoside nLc6Cer(d18:1(4E)) + GDP-beta-L-fucose = a neolactoside III(3)-alpha-Fuc-nLc6Cer(d18:1(4E)) + GDP + H(+)

Left to rightBalance undeterminableRhea 48336

a medium-chain fatty acid + ATP + CoA = a medium-chain fatty acyl-CoA + AMP + diphosphate

Left to rightBalance undeterminableRhea 48340

an N-acyl-sphingoid base + UDP-alpha-D-galactose = a beta-D-Gal-(1<->1')-ceramide + UDP + H(+)

Direction not assertedBalance undeterminableRhea 48344

a uridine in RNA = a pseudouridine in RNA

Direction not assertedBalance undeterminableRhea 48348

a neolactoside VI(3)-alpha-NeuNAc-nLc6Cer + GDP-beta-L-fucose = a neolactoside VI(3)-alpha-NeuAc,III(3)-alphaFuc-nLc6Cer + GDP + H(+)

Left to rightBalance undeterminableRhea 48352

a neolactoside VI(3)-alpha-NeuNAc-nLc6Cer + GDP-beta-L-fucose = a neolactoside VI(3)-alpha-NeuAc,V(3)-alphaFuc-nLc6Cer + GDP + H(+)

Left to rightBalance undeterminableRhea 48356

Page 439 of 629