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CompoundsSubstances with curated findings
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ReactionsRhea and Human-GEM, by subsystem
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Reference

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Computational infrastructure for human biology, built on a provenance-aware knowledge graph. Findings retain their sources; research and simulation are the next layers.

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A reference for what the literature reports. Not medical advice.

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Index

Reactions

Reactions from Rhea and Human-GEM · Reach

reactions in the graph: 31,435

By source

Rhea18,558
Human-GEM12,877

Inferred

Reference data, not a finding. Evidence key

Filter reactions by equationSource

Reactions

21,801–21,850 of 31,435, by identifier

demethylphylloquinone + NADPH + H(+) = demethylphylloquinol + NADP(+)
Direction not assertedBalancedRhea 47744
a ubiquinone + n Na(+)(in) + NADH + H(+) = a ubiquinol + n Na(+)(out) + NAD(+)
Direction not assertedBalance undeterminableTransportRhea 47748
5-hydroxy-3-methyl-L-tyrosine + S-adenosyl-L-methionine = 5-hydroxy-3-methyl-O-methyl-L-tyrosine + S-adenosyl-L-homocysteine + H(+)
Direction not assertedBalancedRhea 47752
guanosine(1370) in 16S rRNA + S-adenosyl-L-methionine = 2'-O-methylguanosine(1370) in 16S rRNA + S-adenosyl-L-homocysteine + H(+)
Direction not assertedBalancedRhea 47756
a uridine in 21S rRNA + S-adenosyl-L-methionine = a 2'-O-methyluridine in 21S rRNA + S-adenosyl-L-homocysteine + H(+)
Direction not assertedBalance undeterminableRhea 47760
uridine(1369) in 16S rRNA + S-adenosyl-L-methionine = 2'-O-methyluridine(1369) in 16S rRNA + S-adenosyl-L-homocysteine + H(+)
Direction not asserted

Balanced

Rhea 47764

guanosine(2270) in 21S rRNA + S-adenosyl-L-methionine = 2'-O-methylguanosine(2270) in 21S rRNA + S-adenosyl-L-homocysteine + H(+)

Direction not assertedBalancedRhea 47768

a guanosine in 21S rRNA + S-adenosyl-L-methionine = a 2'-O-methylguanosine in 21S rRNA + S-adenosyl-L-homocysteine + H(+)

Direction not assertedBalance undeterminableRhea 47772

guanosine(1145) in 16S rRNA + S-adenosyl-L-methionine = 2'-O-methylguanosine(1145) in 16S rRNA + S-adenosyl-L-homocysteine + H(+)

Direction not assertedBalancedRhea 47776

a cytidine in 25S rRNA + S-adenosyl-L-methionine = a 5-methylcytidine in 25S rRNA + S-adenosyl-L-homocysteine + H(+)

Direction not assertedBalance undeterminableRhea 47780

cytidine(3782) in 28S rRNA + S-adenosyl-L-methionine = 5-methylcytidine(3782) in 28S rRNA + S-adenosyl-L-homocysteine + H(+)

Left to rightBalancedRhea 47784

a cytidine in 28S rRNA + S-adenosyl-L-methionine = a 5-methylcytidine in 28S rRNA + S-adenosyl-L-homocysteine + H(+)

Direction not assertedBalance undeterminableRhea 47788

cytidine(4447) in 28S rRNA + S-adenosyl-L-methionine = 5-methylcytidine(4447) in 28S rRNA + S-adenosyl-L-homocysteine + H(+)

Direction not assertedBalancedRhea 47792

an aralkylamine + 2 oxidized [azurin] + H2O = an aromatic aldehyde + 2 reduced [azurin] + NH4(+) + 2 H(+)

Direction not assertedBalance undeterminableRhea 47796

an aromatic L-alpha-amino acid + 4-methylsulfanyl-2-oxobutanoate = an aromatic oxo-acid + L-methionine

Direction not assertedBalance undeterminableRhea 47800

epothilone C + 2 reduced [2Fe-2S]-[ferredoxin] + O2 + 2 H(+) = epothilone A + 2 oxidized [2Fe-2S]-[ferredoxin] + H2O

Direction not assertedBalance undeterminableRhea 47804

epothilone D + 2 reduced [2Fe-2S]-[ferredoxin] + O2 + 2 H(+) = epothilone B + 2 oxidized [2Fe-2S]-[ferredoxin] + H2O

Direction not assertedBalance undeterminableRhea 47808

N(6)-(dimethylallyl)adenosine 5'-phosphate + NADPH + O2 + H(+) = 9-ribosyl-trans-zeatin 5'-phosphate + NADP(+) + H2O

Direction not assertedBalancedRhea 47812

N(6)-(dimethylallyl)adenosine 5'-diphosphate + NADPH + O2 + H(+) = 9-ribosyl-trans-zeatin 5'-diphosphate + NADP(+) + H2O

Direction not assertedBalancedRhea 47816

N(6)-(dimethylallyl)adenosine 5'-triphosphate + NADPH + O2 + H(+) = 9-ribosyl-trans-zeatin 5'-triphosphate + NADP(+) + H2O

Direction not assertedBalancedRhea 47820

octadecanoyl-[ACP] + malonyl-[ACP] + H(+) = 3-oxoeicosanoyl-[ACP] + holo-[ACP] + CO2

Direction not assertedBalance undeterminableRhea 47824

a ganglioside GT1b + H2O = a ganglioside GD1b + N-acetylneuraminate

Left to rightBalance undeterminableRhea 47828

a ganglioside GD1a + H2O = a ganglioside GM1 + N-acetylneuraminate

Left to rightBalance undeterminableRhea 47832

[5-(aminomethyl)-3-furyl]methyl phosphate + ATP = [5-(aminomethyl)furan-3-yl]methyl diphosphate + ADP

Direction not assertedBalancedRhea 47836

gamma-L-glutamyltyramine + [5-(aminomethyl)furan-3-yl]methyl diphosphate = (4-{4-[2-(gamma-L-glutamylamino)ethyl]phenoxymethyl}furan-2-yl)methanamine + diphosphate

Direction not assertedBalancedRhea 47840

2-[(2R,5Z)-2-carboxy-4-methylthiazol-5(2H)-ylidene]ethyl phosphate + 4-amino-2-methyl-5-(diphosphooxymethyl)pyrimidine + 2 H(+) = thiamine phosphate + CO2 + diphosphate

Direction not assertedBalancedRhea 47844

2-(2-carboxy-4-methylthiazol-5-yl)ethyl phosphate + 4-amino-2-methyl-5-(diphosphooxymethyl)pyrimidine + 2 H(+) = thiamine phosphate + CO2 + diphosphate

Direction not assertedBalancedRhea 47848

a neolactoside IV(3)-alpha-NeuAc-nLc4Cer(d18:1(4E)) + H2O = a neolactoside nLc4Cer(d18:1(4E)) + N-acetylneuraminate

Left to rightBalance undeterminableRhea 47852

a ganglioside GD1a (d18:1(4E)) + H2O = a ganglioside GM1 (d18:1(4E)) + N-acetylneuraminate

Left to rightBalance undeterminableRhea 47856

a ganglioside GT1b (d18:1(4E)) + H2O = a ganglioside GD1b (d18:1(4E)) + N-acetylneuraminate

Direction not assertedBalance undeterminableRhea 47860

1,2,3-trioctanoylglycerol + H2O = dioctanoylglycerol + octanoate + H(+)

Left to rightBalancedRhea 47864

di-(9Z)-octadecenoylglycerol + H2O = (9Z-octadecenoyl)-glycerol + (9Z)-octadecenoate + H(+)

Left to rightBalancedRhea 47868

a ganglioside GM1 + H2O = a ganglioside GA1 + N-acetylneuraminate

Left to rightBalance undeterminableRhea 47872

a ganglioside GD1b + H2O = a ganglioside GM1 + N-acetylneuraminate

Left to rightBalance undeterminableRhea 47876

dioctanoylglycerol + H2O = octanoylglycerol + octanoate + H(+)

Direction not assertedBalancedRhea 47880

N-acetyl-alpha-neuraminosyl-(2->3)-beta-D-galactosyl-(1->3)-N-acetyl-beta-D-glucosaminyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1')-N-acyl-sphing-4-enine + CMP-N-acetyl-beta-neuraminate = N-acetyl-alpha-neuraminosyl-(2->3)-beta-D-galactosyl-(1->3)-[N-acetyl-alpha-neuraminosyl-(2->6)]-N-acetyl-beta-D-glucosaminyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1')-N-acyl-sphing-4-enine + CMP + H(+)

Left to rightBalance undeterminableRhea 47884

N-acetyl-alpha-neuraminosyl-(2->3)-beta-D-galactosyl-(1->3)-N-acetyl-beta-D-glucosaminyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1')-N-acyl-sphing-4-enine + GDP-beta-L-fucose = N-acetyl-alpha-neuraminosyl-(2->3)-beta-D-galactosyl-(1->3)-alpha-L-fucosyl-(1->4)-[N-acetyl-beta-D-glucosaminyl-(1->3)]-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1')-N-acyl-sphing-4-enine + GDP + H(+)

Left to rightBalance undeterminableRhea 47888

N-acetyl-alpha-neuraminosyl-(2->3)-beta-D-galactosyl-(1->3)-[N-acetyl-alpha-neuraminosyl-(2->6)]-N-acetyl-beta-D-glucosaminyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1')-N-acyl-sphing-4-enine + GDP-beta-L-fucose = N-acetyl-alpha-neuraminosyl-(2->3)-beta-D-galactosyl-(1->3)-alpha-L-fucosyl-(1->4)-[N-acetyl-alpha-neuraminosyl-(2->6)-N-acetyl-beta-D-glucosaminyl-(1->3)]-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1')-N-acyl-sphing-4-enine + GDP + H(+)

Left to rightBalance undeterminableRhea 47892

6-sulfo-D-quinovose + NAD(+) = 6-deoxy-6-sulfo-D-glucono-1,5-lactone + NADH + H(+)

Direction not assertedBalancedRhea 47896

a ganglioside GM3 (d18:1(4E)) + H2O = a beta-D-Gal-(1->4)-beta-D-Glc-(1<->1)-Cer(d18:1(4E)) + N-acetylneuraminate

Left to rightBalance undeterminableRhea 47900

N-(acetyl)-sphing-4-enine + ATP = N-(acetyl)-sphing-4-enine-1-phosphate + ADP + H(+)

Left to rightBalancedRhea 47904

6-deoxy-6-sulfo-D-glucono-1,5-lactone + H2O = 6-deoxy-6-sulfo-D-gluconate + H(+)

Direction not assertedBalancedRhea 47908

6-deoxy-6-sulfo-D-gluconate = 2-dehydro-3,6-dideoxy-6-sulfo-D-gluconate + H2O

Direction not assertedBalancedRhea 47912

N-hexanoyl-(4R)-hydroxysphinganine + ATP = N-hexanoyl-(4R)-hydroxysphinganine-1-phosphate + ADP + H(+)

Left to rightBalancedRhea 47916

ganglioside GM2 (d18:1(4E)/18:0) + H2O = ganglioside GA2 (d18:1(4E)/18:0) + N-acetylneuraminate

Direction not assertedBalancedRhea 47920

2-dehydro-3,6-dideoxy-6-sulfo-D-gluconate = (2S)-3-sulfolactaldehyde + pyruvate

Direction not assertedBalancedRhea 47924

(2S)-3-sulfolactaldehyde + NADP(+) + H2O = (2S)-3-sulfolactate + NADPH + 2 H(+)

Direction not assertedBalancedRhea 47928

(2S)-3-sulfolactaldehyde + NAD(+) + H2O = (2S)-3-sulfolactate + NADH + 2 H(+)

Direction not assertedBalancedRhea 47932

4-hydroxybenzaldehyde + NADP(+) + H2O = 4-hydroxybenzoate + NADPH + 2 H(+)

Direction not assertedBalancedRhea 47936

a ganglioside GM2 (d18:1(4E)) + H2O = a ganglioside GM3 (d18:1(4E)) + N-acetyl-beta-D-galactosamine

Left to rightBalance undeterminableRhea 47940

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