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CompoundsSubstances with curated findings
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ProteinsTransporters and enzymes
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ReactionsRhea and Human-GEM, by subsystem
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PathwaysReactions grouped under one name
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Reference

Evidence

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Reach

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Computational infrastructure for human biology, built on a provenance-aware knowledge graph. Findings retain their sources; research and simulation are the next layers.

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A reference for what the literature reports. Not medical advice.

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Index

Reactions

Reactions from Rhea and Human-GEM · Reach

reactions in the graph: 31,435

By source

Rhea18,558
Human-GEM12,877

Inferred

Reference data, not a finding. Evidence key

Filter reactions by equationSource

Reactions

20,451–20,500 of 31,435, by identifier

(5Z,8Z,11Z,14Z)-eicosatetraenoate + O2 = (15R)-hydroperoxy-(5Z,8Z,11Z,13E)-eicosatetraenoate
Left to rightBalancedRhea 42284
6-carboxyhexanoyl-[ACP] + L-alanine + H(+) = (8S)-8-amino-7-oxononanoate + holo-[ACP] + CO2
Direction not assertedBalance undeterminableRhea 42288
a fatty acyl-[ACP] + phosphate = an acyl phosphate + holo-[ACP]
Direction not assertedBalance undeterminableRhea 42292
a fatty acyl-[ACP] + a 1-acyl-sn-glycero-3-phosphate = a 1,2-diacyl-sn-glycero-3-phosphate + holo-[ACP]
Direction not assertedBalance undeterminableRhea 42296
a fatty acyl-[ACP] + sn-glycerol 3-phosphate = a 1-acyl-sn-glycero-3-phosphate + holo-[ACP]
Direction not assertedBalance undeterminableRhea 42300
1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phospho-(1'-sn-glycerol-3'-phosphate) + H2O = 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phospho-(1'-sn-glycerol) + phosphate
Left to rightBalancedRhea

42304

1,2-dioctanoyl-sn-glycero-3-phospho-(1D-myo-inositol-5-phosphate) + H2O = 1,2-dioctanoyl-sn-glycero-3-phospho-(1D-myo-inositol) + phosphate

Left to rightBalancedRhea 42308

2 reduced [adrenodoxin] + NADP(+) + H(+) = 2 oxidized [adrenodoxin] + NADPH

Direction not assertedBalance undeterminableRhea 42312

a 2-oxocarboxylate + 2 oxidized [2Fe-2S]-[ferredoxin] + CoA = an acyl-CoA + 2 reduced [2Fe-2S]-[ferredoxin] + CO2 + H(+)

Direction not assertedBalance undeterminableRhea 42316

a 1-acyl-2-hexanoyl-sn-glycero-3-phospho-(1D-myo-inositol-5-phosphate) + H2O = a 1-acyl-2-hexanoyl-sn-glycero-3-phospho-(1D-myo-inositol) + phosphate

Left to rightBalance undeterminableRhea 42320

reduced coenzyme F420-(gamma-L-Glu)(n) + 2 oxidized [2Fe-2S]-[ferredoxin] = oxidized coenzyme F420-(gamma-L-Glu)(n) + 2 reduced [2Fe-2S]-[ferredoxin] + 3 H(+)

Direction not assertedBalance undeterminableRhea 42324

1,2-dioctanoyl-sn-glycero-3-phospho-(1-D-myo-inositol-3-phosphate) + H2O = 1,2-dioctanoyl-sn-glycero-3-phospho-(1D-myo-inositol) + phosphate

Left to rightBalancedRhea 42328

oxidized coenzyme F420-2 + L-glutamate + ATP = oxidized coenzyme alpha-F420-3 + ADP + phosphate + H(+)

Direction not assertedBalancedRhea 42332

[thioredoxin]-disulfide + 2 reduced [2Fe-2S]-[ferredoxin] + 2 H(+) = [thioredoxin]-dithiol + 2 oxidized [2Fe-2S]-[ferredoxin]

Direction not assertedBalance undeterminableRhea 42336

4-(gamma-L-glutamylamino)butanal + NAD(+) + H2O = 4-(gamma-L-glutamylamino)butanoate + NADH + 2 H(+)

Direction not assertedBalancedRhea 42340

p-cumate + NADH + O2 + H(+) = (2R,3S)-2,3-dihydroxy-2,3-dihydro-p-cumate + NAD(+)

Direction not assertedBalancedRhea 42344

1,2-dihexadecanoyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ATP = 1,2-dihexadecanoyl-sn-glycero-3-phospho-(1D-myo-inositol-3,5-bisphosphate) + ADP + H(+)

Direction not assertedBalancedRhea 42348

(R)-nicotine + A + H2O = (R)-6-hydroxynicotine + AH2

Direction not assertedBalancedRhea 42352

(9Z)-tetradecenoyl-CoA + malonyl-CoA + H(+) = 3-oxo-(11Z)-hexadecenoyl-CoA + CO2 + CoA

Direction not assertedBalancedRhea 42356

D-allulose = keto-D-fructose

Direction not assertedBalancedRhea 42360

2 a 2-acyl-sn-glycero-3-phosphocholine = sn-glycerol 3-phosphocholine + a 1,2-diacyl-sn-glycero-3-phosphocholine

Left to rightBalance undeterminableRhea 42364

dihydromonacolin L carboxylate + reduced [NADPH--hemoprotein reductase] + O2 = monacolin L carboxylate + oxidized [NADPH--hemoprotein reductase] + 2 H2O + H(+)

Direction not assertedBalance undeterminableRhea 42368

all-trans-4,4'-diapolycopene-4,4'-dial + 2 A + 2 H2O = all-trans-4,4'-diapolycopene-4,4'-dioate + 2 AH2 + 2 H(+)

Direction not assertedBalancedRhea 42380

4,4'-diaponeurosporenal + NAD(+) + H2O = 4,4'-diaponeurosporenoate + NADH + 2 H(+)

Direction not assertedBalancedRhea 42384

beta-D-glucosyl crocetin + UDP-alpha-D-glucose = beta-D-gentiobiosyl crocetin + UDP + H(+)

Direction not assertedBalancedRhea 42388

D-galactose + NAD(+) = D-galactono-1,5-lactone + NADH + H(+)

Direction not assertedBalancedRhea 42392

cytidine(32)/guanosine(34) in tRNA + 2 S-adenosyl-L-methionine = 2'-O-methylcytidine(32)/2'-O-methylguanosine(34) in tRNA + 2 S-adenosyl-L-homocysteine + 2 H(+)

Direction not assertedBalance undeterminableRhea 42396

lactose(out) + N(pros)-phospho-L-histidyl-[protein] = lactose 6-phosphate(in) + L-histidyl-[protein]

Direction not assertedBalance undeterminableRhea 42400

lactose 6-phosphate + H2O = D-galactose 6-phosphate + beta-D-glucose

Direction not assertedBalancedRhea 42404

(2R)-2-phosphoglycerate + ATP = (2R)-2,3-bisphosphoglycerate + ADP + H(+)

Direction not assertedBalancedRhea 42408

(2R)-2,3-bisphosphoglycerate + ATP + H(+) = cyclic (2R)-2,3-bisphosphoglycerate + ADP + phosphate

Direction not assertedBalancedRhea 42412

a ubiquinone + L-proline = (S)-1-pyrroline-5-carboxylate + a ubiquinol + H(+)

Direction not assertedBalance undeterminableRhea 42416

L-lysine + 2-oxoglutarate + O2 = (4R)-4-hydroxy-L-lysine + succinate + CO2

Direction not assertedBalancedRhea 42420

2-methylmaleate + H2O = (2R,3S)-3-methylmalate

Direction not assertedBalancedRhea 42424

clavaminate = (3R,5R)-clavulanate-9-aldehyde

Direction not assertedUnbalancedRhea 42428

3-hydroxy-cis,cis-muconate = maleylacetate

Direction not assertedBalancedRhea 42432

N(pros)-phospho-L-histidyl-[protein] + L-ascorbate(out) = L-ascorbate 6-phosphate(in) + L-histidyl-[protein]

Direction not assertedBalance undeterminableRhea 42436

L-aspartate + NAD(+) = iminosuccinate + NADH + H(+)

Direction not assertedBalancedRhea 42440

L-aspartate + NADP(+) = iminosuccinate + NADPH + H(+)

Direction not assertedBalancedRhea 42444

(R)-2-hydroxyglutaryl-CoA = (2E)-glutaconyl-CoA + H2O

Direction not assertedBalancedRhea 42448

4-(2-aminophenyl)-2,4-dioxobutanoate = kynurenate + H2O

Direction not assertedBalancedRhea 42452

4alpha-methylzymosterol = zymosterol

Direction not assertedUnbalancedRhea 42456

dibenzofuran + NADH + O2 + H(+) = biphenyl-2,2',3-triol + NAD(+)

Direction not assertedBalancedRhea 42460

biphenyl-2,2',3-triol + O2 = 2-hydroxy-6-(2-hydroxyphenyl)-6-oxo-cis,cis-hexa-2,4-dienoate + 2 H(+)

Direction not assertedBalancedRhea 42464

2-hydroxy-6-(2-hydroxyphenyl)-6-oxo-cis,cis-hexa-2,4-dienoate + H2O = 2-oxopent-4-enoate + salicylate

Direction not assertedBalancedRhea 42468

dibenzo-p-dioxin + NADH + O2 = 2,2',3-trihydroxydiphenyl ether + NAD(+) + H(+)

Direction not assertedBalancedRhea 42472

2,2',3-trihydroxydiphenyl ether + O2 + H(+) = 2-hydroxy-6-(2-hydroxyphenoxy)-6-oxo-cis,cis-hexa-2,4-dienoate

Direction not assertedBalancedRhea 42476

2-hydroxy-6-(2-hydroxyphenoxy)-6-oxo-cis,cis-hexa-2,4-dienoate + H2O = (2Z,4E)-2-hydroxyhexa-2,4-dienedioate + catechol + H(+)

Direction not assertedBalancedRhea 42480

D-sorbitol(out) + N(pros)-phospho-L-histidyl-[protein] = D-sorbitol 6-phosphate(in) + L-histidyl-[protein]

Direction not assertedBalance undeterminableRhea 42484

baccatin III + (3R)-3-amino-3-phenylpropanoyl-CoA = 3'-N-debenzoyl-2'-deoxytaxol + CoA

Direction not assertedBalancedRhea 42488

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