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CompoundsSubstances with curated findings
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ProteinsTransporters and enzymes
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ReactionsRhea and Human-GEM, by subsystem
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Reference

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Computational infrastructure for human biology, built on a provenance-aware knowledge graph. Findings retain their sources; research and simulation are the next layers.

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A reference for what the literature reports. Not medical advice.

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Index

Reactions

Reactions from Rhea and Human-GEM · Reach

reactions in the graph: 31,435

By source

Rhea18,558
Human-GEM12,877

Inferred

Reference data, not a finding. Evidence key

Filter reactions by equationSource

Reactions

20,401–20,450 of 31,435, by identifier

all-trans-retinal + NAD(+) + H2O = all-trans-retinoate + NADH + 2 H(+)
Left to rightBalancedRhea 42080
9-cis-retinal + NAD(+) + H2O = 9-cis-retinoate + NADH + 2 H(+)
Left to rightBalancedRhea 42084
all-trans-retinal + reduced [NADPH--hemoprotein reductase] + O2 = all-trans-retinoate + oxidized [NADPH--hemoprotein reductase] + H2O + 2 H(+)
Left to rightBalance undeterminableRhea 42088
all-trans-retinol + reduced [NADPH--hemoprotein reductase] + O2 = all-trans-retinal + oxidized [NADPH--hemoprotein reductase] + 2 H2O + H(+)
Left to rightBalance undeterminableRhea 42092
tobramycin + carbamoyl phosphate + ATP + H2O = nebramycin 5' + AMP + phosphate + diphosphate + H(+)
Direction not assertedBalancedRhea 42096
kanamycin A + carbamoyl phosphate + ATP + H2O = 6''-O-carbamoylkanamycin A + AMP + phosphate + diphosphate + H(+)
Direction not assertedBalancedRhea 42100

(20S)-hydroxypregn-4-en-3-one + NAD(+) = progesterone + NADH + H(+)

Direction not assertedBalancedRhea 42108

(20S)-hydroxypregn-4-en-3-one + NADP(+) = progesterone + NADPH + H(+)

Right to leftBalancedRhea 42112

5alpha-androstane-3alpha,17beta-diol + NADP(+) = 17beta-hydroxy-5alpha-androstan-3-one + NADPH + H(+)

Right to leftBalancedRhea 42116

17beta-hydroxy-5alpha-androstan-3-one + NADP(+) = 5alpha-androstan-3,17-dione + NADPH + H(+)

Right to leftBalancedRhea 42120

5alpha-androstane-3alpha,17beta-diol + NAD(+) = androsterone + NADH + H(+)

Direction not assertedBalancedRhea 42124

N-hexadecanoylsphinganine + a 1,2-diacyl-sn-glycero-3-phosphoethanolamine = N-hexadecanoyl-sphinganine-1-phosphoethanolamine + a 1,2-diacyl-sn-glycerol

Left to rightBalance undeterminableRhea 42128

isonocardicin C = nocardicin C

Direction not assertedBalancedRhea 42132

an N-acylsphinganine + a 1,2-diacyl-sn-glycero-3-phosphoethanolamine = an N-acylsphinganine-1-phosphoethanolamine + a 1,2-diacyl-sn-glycerol

Left to rightBalance undeterminableRhea 42136

N-hexadecanoyl-(4R)-hydroxysphinganine + a 1,2-diacyl-sn-glycero-3-phosphocholine = N-hexadecanoyl-(4R)-hydroxysphinganine-phosphocholine + a 1,2-diacyl-sn-glycerol

ReversibleBalance undeterminableRhea 42140

N-hexadecanoyl-(4R)-hydroxysphinganine + a 1,2-diacyl-sn-glycero-3-phosphoethanolamine = N-hexadecanoyl-(4R)-hydroxysphinganine-1-phosphoethanolamine + a 1,2-diacyl-sn-glycerol

Left to rightBalance undeterminableRhea 42144

an N-acyl-(4R)-4-hydroxysphinganine + a 1,2-diacyl-sn-glycero-3-phosphoethanolamine = an N-acyl-(4R)-4-hydroxysphinganine-1-phosphoethanolamine + a 1,2-diacyl-sn-glycerol

Left to rightBalance undeterminableRhea 42148

an N-acyl-(4R)-4-hydroxysphinganine + a 1,2-diacyl-sn-glycero-3-phosphocholine = an N-acyl-(4R)-4-hydroxysphinganine-phosphocholine + a 1,2-diacyl-sn-glycerol

ReversibleBalance undeterminableRhea 42152

androsterone + NADPH + H(+) = 5alpha-androstane-3alpha,17beta-diol + NADP(+)

Left to rightBalancedRhea 42156

(11Z,14Z)-eicosadienoyl-CoA + AH2 + O2 = (5Z,11Z,14Z)-eicosatrienoyl-CoA + A + 2 H2O

Direction not assertedBalancedRhea 42160

(11Z,14Z,17Z)-eicosatrienoyl-CoA + AH2 + O2 = (5Z,11Z,14Z,17Z)-eicosatetraenoyl-CoA + A + 2 H2O

Direction not assertedBalancedRhea 42164

20alpha-hydroxy-5beta-pregnan-3-one + NADP(+) = 5beta-pregnan-3,20-dione + NADPH + H(+)

Right to leftBalancedRhea 42168

(11Z)-eicosenoyl-CoA + AH2 + O2 = (8Z,11Z)-eicosadienoyl-CoA + A + 2 H2O

Direction not assertedBalancedRhea 42172

(9Z)-tetradecenoyl-CoA + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) = (9Z,12Z)-tetradecadienoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O

Direction not assertedBalance undeterminableRhea 42176

(6Z,9Z,12Z)-octadecatrienoyl-CoA + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) = (6Z,9Z,12Z,15Z)-octadecatetraenoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O

Direction not assertedBalance undeterminableRhea 42180

5alpha-androstane-3beta,17beta-diol + NAD(+) = 17beta-hydroxy-5alpha-androstan-3-one + NADH + H(+)

Right to leftBalancedRhea 42184

3beta-hydroxy-5alpha-androstan-17-one + NAD(+) = 5alpha-androstan-3,17-dione + NADH + H(+)

Right to leftBalancedRhea 42188

(9Z)-pentadecenoyl-CoA + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) = (9Z,12Z)-pentadecadienoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O

Direction not assertedBalance undeterminableRhea 42192

(9Z)-heptadecenoyl-CoA + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) = (9Z,12Z)-heptadecadienoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O

Direction not assertedBalance undeterminableRhea 42196

corticosterone + NADP(+) = 11-dehydrocorticosterone + NADPH + H(+)

ReversibleBalancedRhea 42200

corticosterone + NAD(+) = 11-dehydrocorticosterone + NADH + H(+)

Left to rightBalancedRhea 42204

a (Z)-omega-(methylsulfanyl)-N-sulfo-alkylhydroximate S-glucoside + NADPH + O2 + H(+) = a (Z)-omega-(methylsulfinyl)-alkyl-glucosinolate + NADP(+) + H2O

Direction not assertedBalance undeterminableRhea 42208

a 1,2-diacyl-sn-glycero-3-phospho-L-serine + H2O = a 2-acyl-sn-glycero-3-phospho-L-serine + a fatty acid + H(+)

Left to rightBalance undeterminableRhea 42212

1-(9Z-octadecenoyl)-sn-glycero-3-phospho-(1D-myo-inositol) + (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA = 1-(9Z-octadecenoyl)-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phospho-1D-myo-inositol + CoA

Left to rightBalancedRhea 42216

1-heptadecanoyl-sn-glycero-3-phosphate + (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA = 1-heptadecanoyl-2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphate + CoA

Left to rightBalancedRhea 42220

testosterone + A = androst-4-ene-3,17-dione + AH2

Direction not assertedBalancedRhea 42224

17beta-estradiol + A = estrone + AH2

Direction not assertedBalancedRhea 42228

1-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + (9Z)-hexadecenoyl-CoA = 1-(9Z)-octadecenoyl-2-(9Z)-hexadecenoyl-sn-glycero-3-phosphoethanolamine + CoA

Direction not assertedBalancedRhea 42232

1-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + hexadecanoyl-CoA = 1-(9Z-octadecenoyl)-2-hexadecanoyl-sn-glycero-3-phosphoethanolamine + CoA

Direction not assertedBalancedRhea 42236

1-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + tetradecanoyl-CoA = 1-(9Z)-octadecenoyl-2-tetradecanoyl-sn-glycero-3-phosphoethanolamine + CoA

Direction not assertedBalancedRhea 42240

malonyl-[ACP] + propanoyl-CoA + H(+) = 3-oxopentanoyl-[ACP] + CO2 + CoA

Direction not assertedBalance undeterminableRhea 42244

butanoyl-CoA + malonyl-[ACP] + H(+) = 3-oxohexanoyl-[ACP] + CO2 + CoA

Direction not assertedBalance undeterminableRhea 42248

pentanoyl-CoA + malonyl-[ACP] + H(+) = 3-oxoheptanoyl-[ACP] + CO2 + CoA

Direction not assertedBalance undeterminableRhea 42252

hexanoyl-CoA + malonyl-[ACP] + H(+) = 3-oxooctanoyl-[ACP] + CO2 + CoA

Direction not assertedBalance undeterminableRhea 42256

heptanoyl-CoA + malonyl-[ACP] + H(+) = 3-oxononanoyl-[ACP] + CO2 + CoA

Direction not assertedBalance undeterminableRhea 42260

octanoyl-CoA + malonyl-[ACP] + H(+) = 3-oxodecanoyl-[ACP] + CO2 + CoA

Direction not assertedBalance undeterminableRhea 42264

2-methylpropanoyl-CoA + malonyl-[ACP] + H(+) = 4-methyl-3-oxopentanoyl-[ACP] + CO2 + CoA

Direction not assertedBalance undeterminableRhea 42268

3-methylbutanoyl-CoA + malonyl-[ACP] + H(+) = 5-methyl-3-oxohexanoyl-[ACP] + CO2 + CoA

Direction not assertedBalance undeterminableRhea 42272

(2S)-2-methylbutanoyl-CoA + malonyl-[ACP] + H(+) = (4S)-4-methyl-3-oxohexanoyl-[ACP] + CO2 + CoA

Direction not assertedBalance undeterminableRhea 42276

(5Z,8Z,11Z,14Z)-eicosatetraenoate + O2 = 11R-hydroperoxy-(5Z,8Z,12E,14Z)-eicosatetraenoate

Left to rightBalancedRhea 42280

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