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CompoundsSubstances with curated findings
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ProteinsTransporters and enzymes
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ReactionsRhea and Human-GEM, by subsystem
ReachWhat a compound can become

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PathwaysReactions grouped under one name
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MaterialsSubstances that are not one molecule
AssessmentsRegulatory determinations, transcribed
DiseasesFeatures, genes, and where each sits

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Reference

Evidence

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Reactions
Reach

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Diseases

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Computational infrastructure for human biology, built on a provenance-aware knowledge graph. Findings retain their sources; research and simulation are the next layers.

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A reference for what the literature reports. Not medical advice.

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Index

Reactions

Reactions from Rhea and Human-GEM · Reach

reactions in the graph: 31,435

By source

Rhea18,558
Human-GEM12,877

Inferred

Reference data, not a finding. Evidence key

Filter reactions by equationSource

Reactions

20,301–20,350 of 31,435, by identifier

a 4-hydroxy-3-(all-trans-polyprenyl)benzoate + H(+) = a 2-(all-trans-polyprenyl)phenol + CO2
Direction not assertedBalance undeterminableRhea 41680
1-O-(9Z-octadecenyl)-sn-glycero-3-phosphocholine + H2O = 1-O-(9Z-octadecenyl)-sn-glycero-3-phosphate + choline + H(+)
Left to rightBalancedRhea 41684
1-O-hexadecyl-2-propanoyl-sn-glycero-3-phosphocholine + H2O = 1-O-hexadecyl-sn-glycero-3-phosphocholine + propanoate + H(+)
Left to rightBalancedRhea 41688
1-O-hexadecyl-2-butanoyl-sn-glycero-3-phosphocholine + H2O = 1-O-hexadecyl-sn-glycero-3-phosphocholine + butanoate + H(+)
Left to rightBalancedRhea 41692
1-O-hexadecyl-2-succinyl-sn-glycero-3-phosphocholine + H2O = 1-O-hexadecyl-sn-glycero-3-phosphocholine + succinate + H(+)
Left to rightBalancedRhea 41696
1-O-hexadecyl-2-glutaryl-sn-glycero-3-phosphocholine + H2O = 1-O-hexadecyl-sn-glycero-3-phosphocholine + glutarate + H(+)
Left to rightBalancedRhea

41700

1-O-hexadecyl-2-acetyl-sn-glycero-3-phosphate + H2O = 1-O-hexadecyl-sn-glycero-3-phosphate + acetate + H(+)

Left to rightBalancedRhea 41704

1-O-hexadecyl-2-acetyl-sn-glycero-3-phosphoethanolamine + H2O = 1-O-hexadecyl-sn-glycero-3-phosphoethanolamine + acetate + H(+)

Left to rightBalancedRhea 41708

a 2-acyl-sn-glycero-3-phosphocholine + H2O = a 2-acyl-sn-glycerol 3-phosphate + choline + H(+)

Left to rightBalance undeterminableRhea 41712

a 2-acyl-sn-glycero-3-phospho-L-serine + H2O = a 2-acyl-sn-glycerol 3-phosphate + L-serine + H(+)

Left to rightBalance undeterminableRhea 41716

a 1-(9Z-octadecenoyl)-2-acyl-sn-glycero-3-phosphocholine + H2O = a 2-acyl-sn-glycero-3-phosphocholine + (9Z)-octadecenoate + H(+)

Left to rightBalance undeterminableRhea 41720

dodecanoate + reduced [NADPH--hemoprotein reductase] + O2 = (11R)-hydroxydodecanoate + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Direction not assertedBalance undeterminableRhea 41724

(9Z)-octadecenoate + reduced [NADPH--hemoprotein reductase] + O2 = 18-hydroxy-(9Z)-octadecenoate + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Left to rightBalance undeterminableRhea 41728

[(1->4)-alpha-D-glucosyl](n) + phosphate = [(1->4)-alpha-D-glucosyl](n-1) + alpha-D-glucose 1-phosphate

Left to rightBalance undeterminableRhea 41732

a beta-D-Gal-(1->4)-beta-D-Glc-(1<->1)-Cer(d18:1(4E)) + 3'-phosphoadenylyl sulfate = beta-D-3-sulfogalactosyl-(1->4)-beta-D-glucosyl-(1<->1')-N-acylsphing-4-enine + adenosine 3',5'-bisphosphate + H(+)

Left to rightBalance undeterminableRhea 41736

adenosine(57)/adenosine(58) in tRNA + 2 S-adenosyl-L-methionine = N(1)-methyladenosine(57)/N(1)-methyladenosine(58) in tRNA + 2 S-adenosyl-L-homocysteine + 2 H(+)

Direction not assertedUnbalancedRhea 41740

a 1-O-alkyl-2-acyl-3-O-(beta-D-galactosyl)-sn-glycerol + 3'-phosphoadenylyl sulfate = a 1-O-alkyl-2-acyl-3-(beta-D-3-sulfogalactosyl)-sn-glycerol + adenosine 3',5'-bisphosphate + H(+)

Left to rightBalance undeterminableRhea 41744

a 1,2-diacyl-3-O-(beta-D-galactosyl)-sn-glycerol + 3'-phosphoadenylyl sulfate = 1,2-diacyl-3-(3-O-sulfo-beta-D-galactosyl)-sn-glycerol + adenosine 3',5'-bisphosphate + H(+)

Left to rightBalance undeterminableRhea 41748

1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phospho-L-serine + H2O = 1-hexadecanoyl-sn-glycero-3-phospho-L-serine + (9Z)-octadecenoate + H(+)

Left to rightBalancedRhea 41752

1-O-methyl-(9Z,12Z)-octadecadienoate + O2 = 1-O-methyl-(13S)-hydroperoxy-(9Z,11E)-octadecadienoate

Left to rightBalancedRhea 41756

a ganglioside GM3 (d18:1(4E)) + CMP-N-acetyl-beta-neuraminate = a ganglioside GD3 (d18:1(4E)) + CMP + H(+)

Left to rightBalance undeterminableRhea 41760

a ganglioside GD3 (d18:1(4E)) + CMP-N-acetyl-beta-neuraminate = a ganglioside GT3 (d18:1(4E)) + CMP + H(+)

Left to rightBalance undeterminableRhea 41764

a ganglioside GD1a (d18:1(4E)) + CMP-N-acetyl-beta-neuraminate = a ganglioside GT1a (d18:1(4E)) + CMP + H(+)

Left to rightBalance undeterminableRhea 41768

a ganglioside GT1b (d18:1(4E)) + CMP-N-acetyl-beta-neuraminate = a ganglioside GQ1b (d18:1(4E)) + CMP + H(+)

Left to rightBalance undeterminableRhea 41772

ganglioside GA2 (d18:1(4E)/18:0) + CMP-N-acetyl-beta-neuraminate = ganglioside GM2 (d18:1(4E)/18:0) + CMP + H(+)

Left to rightBalancedRhea 41776

a beta-D-Gal-(1<->1')-ceramide + CMP-N-acetyl-beta-neuraminate = N-acetyl-alpha-neuraminosyl-(2->3)-beta-D-galactosyl-(1<->1')-ceramide + CMP + H(+)

Left to rightBalance undeterminableRhea 41780

ganglioside GA1 (d18:1(4E)/18:0) + CMP-N-acetyl-beta-neuraminate = ganglioside GM1 (d18:1(4E)/18:0) + CMP + H(+)

Left to rightBalancedRhea 41784

holo-[ACP] + acetyl-CoA = acetyl-[ACP] + CoA

Left to rightBalance undeterminableRhea 41788

holo-[ACP] + malonyl-CoA = malonyl-[ACP] + CoA

Left to rightBalance undeterminableRhea 41792

N-hexadecanoylsphinganine + a 1,2-diacyl-sn-glycero-3-phosphocholine = N-hexadecanoyl-sphinganine-1-phosphocholine + a 1,2-diacyl-sn-glycerol

ReversibleBalance undeterminableRhea 41796

acetyl-[ACP] + malonyl-[ACP] + H(+) = 3-oxobutanoyl-[ACP] + holo-[ACP] + CO2

Left to rightBalance undeterminableRhea 41800

3-oxobutanoyl-[ACP] + NADPH + H(+) = (3R)-hydroxybutanoyl-[ACP] + NADP(+)

Left to rightBalance undeterminableRhea 41804

(3R)-hydroxybutanoyl-[ACP] = (2E)-butenoyl-[ACP] + H2O

Left to rightBalance undeterminableRhea 41808

(2E)-butenoyl-[ACP] + NADPH + H(+) = butanoyl-[ACP] + NADP(+)

Left to rightBalance undeterminableRhea 41812

a ganglioside GD3 (d18:1(4E)) + UDP-N-acetyl-alpha-D-galactosamine = a ganglioside GD2 (d18:1(4E)) + UDP + H(+)

Left to rightBalance undeterminableRhea 41816

butanoyl-[ACP] + malonyl-[ACP] + H(+) = 3-oxohexanoyl-[ACP] + holo-[ACP] + CO2

Left to rightBalance undeterminableRhea 41820

3-oxohexanoyl-[ACP] + NADPH + H(+) = (3R)-hydroxyhexanoyl-[ACP] + NADP(+)

Left to rightBalance undeterminableRhea 41824

(3R)-hydroxyhexanoyl-[ACP] = (2E)-hexenoyl-[ACP] + H2O

Left to rightBalance undeterminableRhea 41828

(2E)-hexenoyl-[ACP] + NADPH + H(+) = hexanoyl-[ACP] + NADP(+)

Left to rightBalance undeterminableRhea 41832

hexanoyl-[ACP] + malonyl-[ACP] + H(+) = 3-oxooctanoyl-[ACP] + holo-[ACP] + CO2

Left to rightBalance undeterminableRhea 41836

3-oxooctanoyl-[ACP] + NADPH + H(+) = (3R)-hydroxyoctanoyl-[ACP] + NADP(+)

Left to rightBalance undeterminableRhea 41840

(3R)-hydroxyoctanoyl-[ACP] = (2E)-octenoyl-[ACP] + H2O

Left to rightBalance undeterminableRhea 41844

(2E)-octenoyl-[ACP] + NADPH + H(+) = octanoyl-[ACP] + NADP(+)

Left to rightBalance undeterminableRhea 41848

octanoyl-[ACP] + malonyl-[ACP] + H(+) = 3-oxodecanoyl-[ACP] + holo-[ACP] + CO2

Left to rightBalance undeterminableRhea 41852

3-oxodecanoyl-[ACP] + NADPH + H(+) = (3R)-hydroxydecanoyl-[ACP] + NADP(+)

Left to rightBalance undeterminableRhea 41856

(3R)-hydroxydecanoyl-[ACP] = (2E)-decenoyl-[ACP] + H2O

Left to rightBalance undeterminableRhea 41860

(2E)-decenoyl-[ACP] + NADPH + H(+) = decanoyl-[ACP] + NADP(+)

Left to rightBalance undeterminableRhea 41864

decanoyl-[ACP] + malonyl-[ACP] + H(+) = 3-oxododecanoyl-[ACP] + holo-[ACP] + CO2

Left to rightBalance undeterminableRhea 41868

3-oxododecanoyl-[ACP] + NADPH + H(+) = (3R)-hydroxydodecanoyl-[ACP] + NADP(+)

Left to rightBalance undeterminableRhea 41872

(3R)-hydroxydodecanoyl-[ACP] = (2E)-dodecenoyl-[ACP] + H2O

Left to rightBalance undeterminableRhea 41876

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