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CompoundsSubstances with curated findings
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ProteinsTransporters and enzymes
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ReactionsRhea and Human-GEM, by subsystem
ReachWhat a compound can become

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Reference

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Computational infrastructure for human biology, built on a provenance-aware knowledge graph. Findings retain their sources; research and simulation are the next layers.

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A reference for what the literature reports. Not medical advice.

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Index

Reactions

Reactions from Rhea and Human-GEM · Reach

reactions in the graph: 31,435

By source

Rhea18,558
Human-GEM12,877

Inferred

Reference data, not a finding. Evidence key

Filter reactions by equationSource

Reactions

20,251–20,300 of 31,435, by identifier

ent-sandaracopimaradien-3beta-ol + reduced [NADPH--hemoprotein reductase] + O2 = oryzalexin D + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)
Direction not assertedBalance undeterminableRhea 41472
zymosterol + an acyl-CoA = zymosterol ester + CoA
Direction not assertedBalance undeterminableRhea 41476
episterol + an acyl-CoA = an episterol ester + CoA
Direction not assertedBalance undeterminableRhea 41480
1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + L-serine = 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phospho-L-serine + ethanolamine
Left to rightBalancedRhea 41484
1-hexadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphoethanolamine + L-serine = 1-hexadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphoserine + ethanolamine
Left to rightBalancedRhea 41488
1-octadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphoethanolamine + L-serine = 1-octadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphoserine + ethanolamine

→ Left to right

Balanced

Rhea 41492

1-(1Z-octadecenyl)-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphoethanolamine + L-serine = 1-(1Z-octadecenyl)-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phospho-L-serine + ethanolamine

Left to rightBalancedRhea 41496

1-octadecanoyl-2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphoethanolamine + L-serine = 1-octadecanoyl-2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphoserine + ethanolamine

Left to rightBalancedRhea 41500

L-ornithine + NADPH + O2 = N(5)-hydroxy-L-ornithine + NADP(+) + H2O

Direction not assertedBalancedRhea 41508

L-ornithine + NADH + O2 = N(5)-hydroxy-L-ornithine + NAD(+) + H2O

Direction not assertedBalancedRhea 41512

phylloquinone + reduced [NADPH--hemoprotein reductase] + O2 = omega-hydroxyphylloquinone + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Left to rightBalance undeterminableRhea 41516

menaquinone-4 + reduced [NADPH--hemoprotein reductase] + O2 = omega-hydroxymenaquinone-4 + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Left to rightBalance undeterminableRhea 41520

5 malonyl-CoA + 5 H(+) = naphthalene-1,3,6,8-tetrol + 5 CO2 + 5 CoA + H2O

Direction not assertedBalancedRhea 41524

(2E)-octenoyl-[ACP] + NADH + H(+) = octanoyl-[ACP] + NAD(+)

Direction not assertedBalance undeterminableRhea 41528

(6R)-L-erythro-5,6,7,8-tetrahydrobiopterin + L-phenylalanine + O2 = 3-hydroxy-L-phenylalanine + (4aS,6R)-4a-hydroxy-L-erythro-5,6,7,8-tetrahydrobiopterin

Direction not assertedBalancedRhea 41532

2,7-dihydroxy-5-methyl-1-naphthoate + S-adenosyl-L-methionine = 2-hydroxy-7-methoxy-5-methyl-1-naphthoate + S-adenosyl-L-homocysteine + H(+)

Direction not assertedBalancedRhea 41536

8-demethyl-8-alpha-L-rhamnosyl-tetracenomycin C + S-adenosyl-L-methionine = 8-demethyl-8-(2-O-methyl-alpha-L-rhamnosyl)-tetracenomycin C + S-adenosyl-L-homocysteine + H(+)

Direction not assertedBalancedRhea 41540

8-demethyl-8-(2-O-methyl-alpha-L-rhamnosyl)-tetracenomycin C + S-adenosyl-L-methionine = 8-demethyl-8-(2,3-di-O-methyl-alpha-L-rhamnosyl)-tetracenomycin C + S-adenosyl-L-homocysteine + H(+)

Direction not assertedBalancedRhea 41544

8-demethyl-8-(2,3-di-O-methyl-alpha-L-rhamnosyl)-tetracenomycin C + S-adenosyl-L-methionine = 8-demethyl-8-(2,3,4-tri-O-methyl-alpha-L-rhamnosyl)-tetracenomycin C + S-adenosyl-L-homocysteine + H(+)

Direction not assertedBalancedRhea 41548

(2E,6E,10E,14E)-geranylfarnesyl diphosphate + H2O = ophiobolin F + diphosphate

Direction not assertedBalancedRhea 41552

L-arginyl-[ribosomal protein uL16] + 2-oxoglutarate + O2 = (3R)-3-hydroxy-L-arginyl-[ribosomal protein uL16] + succinate + CO2

Direction not assertedBalance undeterminableRhea 41556

(3S)-3-amino-3-(3-chloro-4-hydroxyphenyl)propanoyl-[SgcC2 peptidyl-carrier protein] + FADH2 + O2 = (3S)-3-amino-3-(3-chloro-4,5-dihydroxyphenyl)propanoyl-[SgcC2 peptidyl-carrier protein] + FAD + H2O + H(+)

Direction not assertedBalance undeterminableRhea 41560

dTDP-beta-L-rhodosamine + aklavinone = aclacinomycin T + dTDP + 2 H(+)

Direction not assertedBalancedRhea 41564

dTDP-2-deoxy-beta-L-fucose + aclacinomycin T = aclacinomycin S + dTDP + H(+)

Direction not assertedBalancedRhea 41568

lipoxin A4 + NAD(+) = 15-oxo-(5S,6R)-dihydroxy-(7E,9E,11Z,13E)-eicosatetraenoate + NADH + H(+)

Left to rightBalancedRhea 41572

dTDP-beta-L-mycarose + erythronolide B = 3-O-alpha-L-mycarosylerythronolide B + dTDP + H(+)

Direction not assertedBalancedRhea 41576

5,10-dihydrophenazine 1-carboxylate + dimethylallyl diphosphate = 5,10-dihydro-9-dimethylallylphenazine 1-carboxylate + diphosphate

Direction not assertedBalancedRhea 41580

L-tyrosine + dimethylallyl diphosphate = 4-O-dimethylallyl-L-tyrosine + diphosphate

Direction not assertedBalancedRhea 41584

a 1-O-(1Z-alkenyl)-sn-glycero-3-phosphocholine + H2O = a 1-O-(1Z-alkenyl)-sn-glycero-3-phosphate + choline + H(+)

Left to rightBalance undeterminableRhea 41588

15-oxo-(5S,6R)-dihydroxy-(7E,9E,11Z,13E)-eicosatetraenoate + NADH + H(+) = 15-oxo-(5S,6R)-dihydroxy-(7E,9E,11Z)-eicosatrienoate + NAD(+)

Direction not assertedBalancedRhea 41592

15-oxo-(5S,6R)-dihydroxy-(7E,9E,11Z)-eicosatrienoate + NADH + H(+) = (5S,6R,15S)-trihydroxy-(7E,9E,11Z)-eicosatrienoate + NAD(+)

Left to rightBalancedRhea 41596

1-(1Z-octadecenyl)-2-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + L-serine = 1-(1Z-octadecenyl)-2-(9Z-octadecenoyl)-sn-glycero-3-phospho-L-serine + ethanolamine

Left to rightBalancedRhea 41600

1-(1Z-octadecenyl)-2-(5Z,8Z,11Z,14Z- eicosatetraenoyl)-sn-glycero-3-phosphoethanolamine + L-serine = 1-(1Z-octadecenyl)-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phospho-L-serine + ethanolamine

Left to rightBalancedRhea 41604

alpha,alpha-trehalose + 3'-phosphoadenylyl sulfate = 2-O-sulfo-alpha,alpha-trehalose + adenosine 3',5'-bisphosphate + H(+)

Direction not assertedBalancedRhea 41608

alpha-D-ribose 1,2-cyclic phosphate 5-phosphate + H2O = D-ribose 2,5-bisphosphate + H(+)

Direction not assertedBalancedRhea 41612

D-ribose 2,5-bisphosphate + H2O = D-ribose 5-phosphate + phosphate

Direction not assertedBalancedRhea 41616

3-sulfinopropanoyl-CoA + H2O = propanoyl-CoA + sulfite + H(+)

Direction not assertedBalancedRhea 41624

geranylgeranyl diphosphate + H2O = cyclooctat-9-en-7-ol + diphosphate

Direction not assertedBalancedRhea 41628

a 1-O-(1Z-alkenyl)-2-acyl-sn-glycero-3-phosphoethanolamine + L-serine = 1-O-(1Z-alkenyl)-2-acyl-sn-glycero-3-phospho-L-serine + ethanolamine

Direction not assertedBalance undeterminableRhea 41632

a 1-O-(1Z-alkenyl)-sn-glycero-3-phosphate + H2O = 1-O-(1Z-alkenyl)-sn-glycerol + phosphate

Direction not assertedBalance undeterminableRhea 41636

3-[(3aS,4S,7aS)-7a-methyl-1,5-dioxo-octahydro-1H-inden-4-yl]propanoate + ATP + CoA = 3-[(3aS,4S,7aS)-7a-methyl-1,5-dioxo-octahydro-1H-inden-4-yl]propanoyl-CoA + AMP + diphosphate

Direction not assertedBalancedRhea 41640

2-hydroxy-7-methoxy-5-methyl-1-naphthoate + ATP + CoA = 2-hydroxy-7-methoxy-5-methyl-1-naphthoyl-CoA + AMP + diphosphate

Direction not assertedBalancedRhea 41644

aniline + L-glutamate + ATP = N(5)-phenyl-L-glutamine + ADP + phosphate

Direction not assertedBalancedRhea 41648

dTDP-2-deoxy-beta-L-fucose + aclacinomycin S = 2-deoxy-alpha-L-fucosylaclacinomycin S + dTDP + H(+)

Direction not assertedBalancedRhea 41652

dihydrosanguinarine + NADP(+) = sanguinarine + NADPH

Direction not assertedBalancedRhea 41656

dihydrosanguinarine + NAD(+) = sanguinarine + NADH

Direction not assertedBalancedRhea 41660

dihydrochelirubine + NAD(+) = chelirubine + NADH

Direction not assertedBalancedRhea 41664

dihydrochelirubine + NADP(+) = chelirubine + NADPH

Direction not assertedBalancedRhea 41668

1-O-hexadecyl-sn-glycerol + ATP = 1-O-hexadecyl-sn-glycero-3-phosphate + ADP + H(+)

Left to rightBalancedRhea 41672

1-O-hexadecyl-2-acetyl-sn-glycerol + ATP = 1-O-hexadecyl-2-acetyl-sn-glycero-3-phosphate + ADP + H(+)

Left to rightBalancedRhea 41676

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