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CompoundsSubstances with curated findings
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ProteinsTransporters and enzymes
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ReactionsRhea and Human-GEM, by subsystem
ReachWhat a compound can become

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Reference

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Computational infrastructure for human biology, built on a provenance-aware knowledge graph. Findings retain their sources; research and simulation are the next layers.

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A reference for what the literature reports. Not medical advice.

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Index

Reactions

Reactions from Rhea and Human-GEM · Reach

reactions in the graph: 31,435

By source

Rhea18,558
Human-GEM12,877

Inferred

Reference data, not a finding. Evidence key

Filter reactions by equationSource

Reactions

20,201–20,250 of 31,435, by identifier

1-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-2-O-hexadecyl-sn-glycero-3-phosphocholine + H2O = 2-O-hexadecyl-sn-glycero-3-phosphocholine + (5Z,8Z,11Z,14Z)-eicosatetraenoate + H(+)
Left to rightBalancedRhea 41271
N-eicosanoyl-sphing-4-enine + H2O = eicosanoate + sphing-4-enine
Left to rightBalancedRhea 41275
N-octadecanoylsphing-4-enine + H2O = sphing-4-enine + octadecanoate
ReversibleBalancedRhea 41279
N-tetracosanoyl-sphing-4-enine + H2O = tetracosanoate + sphing-4-enine
Left to rightBalancedRhea 41283
N-tetradecanoylsphing-4-enine + H2O = sphing-4-enine + tetradecanoate
ReversibleBalancedRhea 41287
N-dodecanoylsphing-4-enine + H2O = dodecanoate + sphing-4-enine
ReversibleBalancedRhea 41291
N-(hexanoyl)sphing-4-enine + H2O = hexanoate + sphing-4-enine

→ Left to right

Balanced

Rhea 41295

N-(9Z-octadecenoyl)-sphing-4-enine + H2O = sphing-4-enine + (9Z)-octadecenoate

ReversibleBalancedRhea 41299

N-dodecanoyl-(4R)-hydroxysphinganine + H2O = (4R)-hydroxysphinganine + dodecanoate

Right to leftBalancedRhea 41303

1-octadecanoyl-2-(9Z,12Z,15Z-octadecatrienoyl)-sn-glycero-3-phosphocholine + H2O = (9Z,12Z,15Z)-octadecatrienoate + 1-octadecanoyl-sn-glycero-3-phosphocholine + H(+)

Left to rightBalancedRhea 41307

1-O-methyl-(5Z,8Z,11Z,14Z)-eicosatetraenoate + O2 = 1-O-methyl (5Z,8Z,10E,12R,14Z)-hydroperoxyiecosatetraenoate

Left to rightBalancedRhea 41311

1-O-methyl-(5Z,8Z,11Z,14Z)-eicosatetraenoate + O2 = 1-O-methyl-(12S)-hydroperoxy-(5Z,8Z,10E,14Z)-eicosatetraenoate

Direction not assertedBalancedRhea 41315

1-O-(9Z)-octadecenoyl-2-O-acetyl-sn-glycero-3-phosphocholine + H2O = 2-acetyl-sn-glycero-3-phosphocholine + (9Z)-octadecenoate + H(+)

Left to rightBalancedRhea 41320

(5Z,8Z,11Z)-eicosatrienoate + O2 = (12S)-hydroperoxy-(5Z,8Z,10E)-eicosatrienoate

Left to rightBalancedRhea 41324

(8Z,11Z,14Z)-eicosatrienoate + O2 = (12S)-hydroperoxy-(8Z,10E,14Z)-eicosatrienoate

Left to rightBalancedRhea 41328

(4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoate + O2 = (14S)-hydroperoxy-(4Z,7Z,10Z,12E,16Z,19Z)-docosahexaenoate

Left to rightBalancedRhea 41332

(5Z,8Z,11Z,14Z)-eicosatetraenoate + O2 = (12R)-hydroperoxy-(5Z,8Z,10E,14Z)-eicosatetraenoate

Left to rightBalancedRhea 41336

(6Z,9Z,12Z)-octadecatrienoate + O2 = 10R-hydroperoxy-(6Z,8E,12Z)-octadecatrienoate

Left to rightBalancedRhea 41340

(5Z,8Z,11Z,14Z,17Z)-eicosapentaenoate + O2 = (5Z,7Z,8Z,10E,14Z,17Z)-12-hydroperoxyeicosapentaenoate

Left to rightBalancedRhea 41344

1-hexadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphoethanolamine + H2O = 2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphoethanolamine + hexadecanoate + H(+)

Left to rightBalancedRhea 41348

a 1-acyl-sn-glycero-3-phospho-(1D-myo-inositol) + 1-hexadecanoyl-sn-glycero-3-phosphocholine = a 1-acyl-2-hexadecanoyl-sn-glycero-3-phospho-(1D-myo-inositol) + sn-glycerol 3-phosphocholine

Left to rightBalance undeterminableRhea 41352

bacteriochlorophyll a + 3 NADP(+) = geranylgeranyl-bacteriochlorophyllide a + 3 NADPH + 3 H(+)

Direction not assertedBalancedRhea 41356

1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + 1,2-dihexadecanoyl-sn-glycero-3-phosphocholine = hexadecanoyl-sn-glycero-3-phosphocholine + N-hexadecanoyl-1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + H(+)

Left to rightBalancedRhea 41360

1,2-dihexadecanoyl-sn-glycero-3-phosphocholine + a 2-acyl-sn-glycero-3-phosphocholine = a 1-hexadecanoyl-2-acyl-sn-glycero-3-phosphocholine + 2-hexadecanoyl-sn-glycero-3-phosphocholine

Left to rightBalance undeterminableRhea 41364

1-O-tetradecyl-2-acetyl-sn-glycero-3-phosphocholine + H2O = 1-O-tetradecyl-sn-glycero-3-phosphocholine + acetate + H(+)

Left to rightBalancedRhea 41368

1-O-dodecyl-2-acetyl-sn-glycero-3-phosphocholine + H2O = 1-O-dodecyl-sn-glycero-3-phosphocholine + acetate + H(+)

Left to rightBalancedRhea 41372

1-O-decyl-2-acetyl-sn-glycero-3-phosphocholine + H2O = 1-O-decyl-sn-glycero-3-phosphocholine + acetate + H(+)

Left to rightBalancedRhea 41376

toluene + NADH + O2 + H(+) = 4-methylphenol + NAD(+) + H2O

Direction not assertedBalancedRhea 41380

1,2-dihexadecanoyl-sn-glycero-3-phosphocholine + H2O = hexadecanoyl-sn-glycero-3-phosphocholine + hexadecanoate + H(+)

Left to rightBalancedRhea 41384

1-hexadecanoyl-2-nonadioyl-sn-glycero-3-phosphocholine + H2O = nonanedioate + 1-hexadecanoyl-sn-glycero-3-phosphocholine + H(+)

Left to rightBalancedRhea 41388

2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphocholine + H2O = 2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphate + choline + H(+)

Direction not assertedBalancedRhea 41392

1-O-hexadecyl-2-acetyl-sn-glycero-3-phosphocholine + a 1-O-(1Z-alkenyl)-sn-glycero-3-phosphoethanolamine = 1-O-(1Z-alkenyl)-2-acetyl-sn-glycero-3-phosphoethanolamine + 1-O-hexadecyl-sn-glycero-3-phosphocholine

Left to rightBalance undeterminableRhea 41396

1-hexanoyl-sn-glycero-3-phosphocholine + H2O = 1-hexanoyl-sn-glycero-3-phosphate + choline + H(+)

Left to rightBalancedRhea 41400

(R)-2-methylpyrrolidine + NADP(+) = 2-methyl-1-pyrroline + NADPH + H(+)

Direction not assertedBalancedRhea 41404

1-O-hexadecyl-2-acetyl-sn-glycero-3-phosphocholine + sphing-4-enine = 1-O-hexadecyl-sn-glycero-3-phosphocholine + N-(acetyl)-sphing-4-enine + H(+)

Left to rightBalancedRhea 41408

1,2-didecanoyl-sn-glycero-3-phosphocholine + H2O = 1,2-didecanoyl-sn-glycero-3-phosphate + choline + H(+)

Left to rightBalancedRhea 41412

1,2-dioctanoyl-sn-glycero-3-phosphocholine + H2O = 1,2-dioctanoyl-sn-glycero-3-phosphate + choline + H(+)

Left to rightBalancedRhea 41416

2 3-amino-4-hydroxybenzoate + N-acetyl-L-cysteine + 2 O2 + H(+) = grixazone B + CO2 + 4 H2O

Direction not assertedBalancedRhea 41420

2 3-amino-4-hydroxybenzaldehyde + N-acetyl-L-cysteine + 2 O2 = grixazone A + formate + 3 H2O + H(+)

Direction not assertedBalancedRhea 41424

L-tyrosine + S-adenosyl-L-methionine = 3-methyl-L-tyrosine + S-adenosyl-L-homocysteine + H(+)

Direction not assertedBalancedRhea 41428

3-methyl-L-tyrosine + H2O2 = 5-hydroxy-3-methyl-L-tyrosine + H2O

Direction not assertedBalancedRhea 41432

cholesterol + (9Z)-octadecenoyl-CoA = cholesteryl (9Z-octadecenoate) + CoA

Left to rightBalancedRhea 41436

(2-aminoethyl)phosphonate + 2-oxoglutarate + O2 = (1R)-(2-amino-1-hydroxyethyl)phosphonate + succinate + CO2

Direction not assertedBalancedRhea 41440

(1R)-(2-amino-1-hydroxyethyl)phosphonate + O2 = glycine + phosphate + 2 H(+)

Direction not assertedBalancedRhea 41444

L-isoleucine + 2-oxoglutarate + O2 = (4S)-4-hydroxy-L-isoleucine + succinate + CO2

Direction not assertedBalancedRhea 41448

5-methyl-1-naphthoate + NADPH + O2 + H(+) = 3-hydroxy-5-methyl-1-naphthoate + NADP(+) + H2O

Direction not assertedBalancedRhea 41452

1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + an N-acylsphing-4-enine = an N-acylsphing-4-enine 1-phosphoethanolamine + 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycerol

Direction not assertedBalance undeterminableRhea 41456

1,2-diacyl-glycero-3-phosphocholine + an N-acylsphing-4-enine = a sphingomyelin + a 1,2-diacylglycerol

Direction not assertedBalance undeterminableRhea 41460

ent-sandaracopimara-8(14),15-diene + reduced [NADPH--hemoprotein reductase] + O2 = ent-sandaracopimaradien-3beta-ol + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Direction not assertedBalance undeterminableRhea 41464

ent-sandaracopimaradien-3beta-ol + reduced [NADPH--hemoprotein reductase] + O2 = oryzalexin E + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Direction not assertedBalance undeterminableRhea 41468

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