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CompoundsSubstances with curated findings
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ProteinsTransporters and enzymes
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ReactionsRhea and Human-GEM, by subsystem
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PathwaysReactions grouped under one name
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AssessmentsRegulatory determinations, transcribed
DiseasesFeatures, genes, and where each sits

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Reference

Evidence

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Computational infrastructure for human biology, built on a provenance-aware knowledge graph. Findings retain their sources; research and simulation are the next layers.

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A reference for what the literature reports. Not medical advice.

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Index

Reactions

Reactions from Rhea and Human-GEM · Reach

reactions in the graph: 31,435

By source

Rhea18,558
Human-GEM12,877

Inferred

Reference data, not a finding. Evidence key

Filter reactions by equationSource

Reactions

18,401–18,450 of 31,435, by identifier

(1R,4R)-5-oxo-1,2-campholide = [(1R)-2,2,3-trimethyl-5-oxocyclopent-3-en-1-yl]acetate + H(+)
Direction not assertedBalancedRhea 33923
4-(6-hydroxypyridin-3-yl)-4-oxobutanoate + 2 NADH + O2 + 2 H(+) = 2,5-dihydroxypyridine + succinate semialdehyde + 2 NAD(+) + H2O
Direction not assertedBalancedRhea 33927
all-trans-zeaxanthin + O2 = (3R)-11-cis-3-hydroxyretinal + (3R)-all-trans-3-hydroxyretinal
Direction not assertedBalancedRhea 33931
2 N(omega)-hydroxy-L-arginine + NADH + 2 O2 = 2 L-citrulline + 2 nitric oxide + NAD(+) + 2 H2O + H(+)
Direction not assertedBalancedRhea 33935
L-arginine + NADH + O2 + H(+) = N(omega)-hydroxy-L-arginine + NAD(+) + H2O
Direction not assertedBalancedRhea 33939
2 L-arginine + 3 NADH + 4 O2 + H(+) = 2 L-citrulline + 2 nitric oxide + 3 NAD(+) + 4 H2O
Direction not assertedBalancedRhea 33943

2-deoxystreptamine + UDP-N-acetyl-alpha-D-glucosamine = 2'-N-acetylparomamine + UDP + H(+)

Direction not assertedBalancedRhea 33947

ribostamycin + UDP-N-acetyl-alpha-D-glucosamine = 2'''-acetyl-6'''-hydroxyneomycin C + UDP + H(+)

Direction not assertedBalancedRhea 33951

DIBOA + UDP-alpha-D-glucose = DIBOA beta-D-glucoside + UDP + H(+)

Direction not assertedBalancedRhea 33955

neomycin C + 2-oxoglutarate = 6'''-deamino-6'''-oxoneomycin C + L-glutamate

Direction not assertedBalancedRhea 33959

isopentenyl phosphate + ATP = isopentenyl diphosphate + ADP

Direction not assertedBalancedRhea 33963

2-oxo-3-(5-oxofuran-2-ylidene)propanoate + H2O = 3-maleylpyruvate + H(+)

Direction not assertedBalancedRhea 33967

5''-phosphoribostamycin + H2O = ribostamycin + phosphate

Direction not assertedBalancedRhea 33971

DIMBOA beta-D-glucoside + H2O = DIMBOA + D-glucose

Direction not assertedBalancedRhea 33975

DIBOA beta-D-glucoside + H2O = DIBOA + D-glucose

Direction not assertedBalancedRhea 33979

(+)-copalyl diphosphate = miltiradiene + diphosphate

Direction not assertedBalancedRhea 33983

(+)-copalyl diphosphate = neoabietadiene + diphosphate

Direction not assertedBalancedRhea 33987

(2E,6E)-farnesyl diphosphate = alpha-copaene + diphosphate

Direction not assertedBalancedRhea 33991

gamma-L-glutamyl-butirosin B = butirosin B + 5-oxo-L-proline

Direction not assertedBalancedRhea 33995

zymosterol = 5alpha-cholesta-7,24-dien-3beta-ol

Left to rightBalancedRhea 33999

5alpha-cholesta-7,24-dien-3beta-ol + NADPH + O2 + H(+) = 7-dehydrodesmosterol + NADP(+) + 2 H2O

Direction not assertedBalancedRhea 34003

7-dehydrodesmosterol + S-adenosyl-L-methionine = 5-dehydroepisterol + S-adenosyl-L-homocysteine + H(+)

Direction not assertedBalancedRhea 34007

5-dehydroepisterol + NADP(+) + 2 H2O = ergosta-5,7-dien-3betabeta-ol + NADPH + O2 + H(+)

Direction not assertedBalancedRhea 34011

ergosta-5,7-dien-3betabeta-ol + NADPH + O2 + H(+) = ergosterol + NADP(+) + 2 H2O

Direction not assertedBalancedRhea 34015

a 1-acylglycerol + H2O = glycerol + a fatty acid + H(+)

Left to rightBalance undeterminableRhea 34019

3,3'-bipyridine-2,2',5,5',6,6'-hexol + NAD(+) = (E)-2,2',5,5'-tetrahydroxy-6H,6'H-(3,3'-bipyridinylidene)-6,6'-dione + NADH + 3 H(+)

Direction not assertedBalancedRhea 34023

3,3'-bipyridine-2,2',5,5',6,6'-hexol + NADP(+) = (E)-2,2',5,5'-tetrahydroxy-6H,6'H-(3,3'-bipyridinylidene)-6,6'-dione + NADPH + 3 H(+)

Direction not assertedBalancedRhea 34027

2'-N-acetylparomamine + H2O = paromamine + acetate

Direction not assertedBalancedRhea 34031

paromamine + O2 = 6'-oxoparomamine + H2O2

Direction not assertedBalancedRhea 34035

neamine + 2-oxoglutarate = 6'-oxoparomamine + L-glutamate

Direction not assertedBalancedRhea 34039

neamine + 5-phospho-alpha-D-ribose 1-diphosphate = 5''-phosphoribostamycin + diphosphate

Direction not assertedBalancedRhea 34043

6'''-deamino-6'''-hydroxyneomycin C + O2 = 6'''-deamino-6'''-oxoneomycin C + H2O2

Direction not assertedBalancedRhea 34047

2'''-acetyl-6'''-hydroxyneomycin C + H2O = 6'''-deamino-6'''-hydroxyneomycin C + acetate

Direction not assertedBalancedRhea 34051

festuclavine + NAD(+) = 6,8-dimethyl-6,7-didehydroergoline + NADH + H(+)

Direction not assertedBalancedRhea 34055

agroclavine + NADP(+) = didehydroagroclavine + NADPH + H(+)

Direction not assertedBalancedRhea 34059

2-deoxystreptamine + UDP-alpha-D-glucose = 2'-deamino-2'-hydroxyparomamine + UDP + H(+)

Direction not assertedBalancedRhea 34063

trans,octa-cis-decaprenyl phosphate + 5-phospho-alpha-D-ribose 1-diphosphate + H(+) = trans,octa-cis-decaprenylphospho-beta-D-ribofuranose 5-phosphate + diphosphate

Direction not assertedBalancedRhea 34067

trans,octa-cis-decaprenyl phosphate + UDP-N-acetyl-alpha-D-glucosamine = N-acetyl-alpha-D-glucosaminyl-1-diphospho-trans,octa-cis-decaprenol + UMP

Direction not assertedBalancedRhea 34071

an acyl phosphate + sn-glycerol 3-phosphate = a 1-acyl-sn-glycero-3-phosphate + phosphate

Direction not assertedBalance undeterminableRhea 34075

a 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycero-3'-phosphate) + ADP + H(+) = a 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol) + ATP

Direction not assertedBalance undeterminableRhea 34079

a (3R)-3-hydroxyacyl-CoA = a (3S)-3-hydroxyacyl-CoA

Direction not assertedBalance undeterminableRhea 34083

cholesterol + a 1,2-diacyl-sn-glycero-3-phosphocholine = a cholesterol ester + a 1-acyl-sn-glycero-3-phosphocholine

Direction not assertedBalance undeterminableRhea 34087

(5R)-5-phosphooxy-L-lysine + H2O = (S)-2-amino-6-oxohexanoate + NH4(+) + phosphate

Direction not assertedBalancedRhea 34091

carboxyspermidine + H(+) = spermidine + CO2

Direction not assertedBalancedRhea 34095

carboxynorspermidine + H(+) = norspermidine + CO2

Direction not assertedBalancedRhea 34099

N-acetyl-alpha-D-glucosaminyl-di-trans,octa-cis-undecaprenyl diphosphate = N-acetyl-alpha-D-galactosaminyl-di-trans,octa-cis-undecaprenyl diphosphate

Direction not assertedBalancedRhea 34103

hexadecanoyl-CoA + glycine + H(+) = 1-deoxymethyl-3-dehydrosphinganine + CO2 + CoA

Direction not assertedBalancedRhea 34107

carboxyspermidine + NADP(+) + H2O = L-aspartate 4-semialdehyde + putrescine + NADPH + H(+)

Direction not assertedBalancedRhea 34111

carboxynorspermidine + NADP(+) + H2O = L-aspartate 4-semialdehyde + propane-1,3-diamine + NADPH + H(+)

Direction not assertedBalancedRhea 34115

hexanoyl-CoA + 3 malonyl-CoA + 3 H(+) = 3,5,7-trioxododecanoyl-CoA + 3 CO2 + 3 CoA

Direction not assertedBalancedRhea 34119

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