Skip to content

Reference

Evidence

CompoundsSubstances with curated findings
OutcomesMeasured endpoints
ProteinsTransporters and enzymes
InteractionsPairs that share biology
PapersEvery paper a finding cites
ArticlesReadings of the evidence

Chemistry

ReactionsRhea and Human-GEM, by subsystem
ReachWhat a compound can become

Reference layer

PathwaysReactions grouped under one name
ProcessesWhat proteins are annotated as doing
AnatomyTissues, by what is expressed there
Cell typesCells, by what is expressed there
OrganismsSpecies a compound is prepared from
MaterialsSubstances that are not one molecule
AssessmentsRegulatory determinations, transcribed
DiseasesFeatures, genes, and where each sits

Atlas Graph Twin Access

Search the graph

Reference

Evidence

Compounds
Outcomes
Proteins
Interactions
Papers
Articles

Chemistry

Reactions
Reach

Reference layer

Pathways
Processes
Anatomy
Cell types
Organisms
Materials
Assessments
Diseases

Atlas Graph Twin Access

Loading the page.

Catalyst

Computational infrastructure for human biology, built on a provenance-aware knowledge graph. Findings retain their sources; research and simulation are the next layers.

The graph

Compounds
Outcomes
Proteins
Atlas
Interactions
Papers
Articles
Graph
Search

Reference layer

Pathways
Processes
Anatomy
Cell types
Organisms
Materials
Assessments
Diseases
Reactions
Reach

How it works

Mission
Method
Twin
How to read the evidence
Sources and licences

Build on it

Access
In your assistant
For agents
Query the graph
Bulk export

A reference for what the literature reports. Not medical advice.

© 2026 CatalystPrivacy TermsReference data under the licences listed on the attribution page.

Index

Reactions

Reactions from Rhea and Human-GEM · Reach

reactions in the graph: 31,435

By source

Rhea18,558
Human-GEM12,877

Inferred

Reference data, not a finding. Evidence key

Filter reactions by equationSource

Reactions

18,351–18,400 of 31,435, by identifier

4-sulfomuconolactone + H2O = maleylacetate + sulfite + 2 H(+)
Direction not assertedBalancedRhea 33711
4-hydroxyeicosasphinganine 1-phosphate = 2-hydroxyoctadecanal + phosphoethanolamine
Direction not assertedBalancedRhea 33715
N-hexacosanoylsphinganine + a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) = N-(hexacosanoyl)-sphinganine-1-(1D-myo-inositol) + a 1,2-diacyl-sn-glycerol
Direction not assertedBalance undeterminableRhea 33719
N-tetracosanoylsphinganine + a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) = N-tetracosanoylsphinganine-(1D-myo-inositol) + a 1,2-diacyl-sn-glycerol
Direction not assertedBalance undeterminableRhea 33723
N-(2-hydroxyhexacosanoyl)-sphinganine + a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) = Ins-1-P-Cer(d18:0/2-OH-26:0) + a 1,2-diacyl-sn-glycerol
Direction not assertedBalance undeterminableRhea 33727
1'-[1,2-diacyl-sn-glycero-3-phospho],3'-[1-acyl-sn-glycero-3-phospho]-glycerol + a 1,2-diacyl-sn-glycero-3-phosphocholine = a cardiolipin + a 1-acyl-sn-glycero-3-phosphocholine

⇌ Reversible

Balance undeterminable

Rhea 33731

hexadecanoate + NADH + 2 H(+) = hexadecanal + NAD(+) + H2O

ReversibleBalancedRhea 33739

an N-acylsphing-4-enine 1-phosphate + H2O = an N-acylsphing-4-enine + phosphate

Left to rightBalance undeterminableRhea 33743

a 1-acyl-sn-glycerol + ATP = a 1-acyl-sn-glycero-3-phosphate + ADP + H(+)

Left to rightBalance undeterminableRhea 33747

a 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycero-3'-phosphate) + H2O = a 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol) + phosphate

Left to rightBalance undeterminableRhea 33751

N-hexadecanoyl-(4R)-hydroxysphinganine + H2O = (4R)-hydroxysphinganine + hexadecanoate

Direction not assertedBalancedRhea 33755

a 3-oxo-fatty acyl-CoA + NADPH + H(+) = a 3-hydroxy-fatty acyl-CoA + NADP(+)

Direction not assertedBalance undeterminableRhea 33759

a (2E)-enoyl-CoA + NADPH + H(+) = a 2,3-saturated acyl-CoA + NADP(+)

Left to rightBalance undeterminableRhea 33763

a 3-hydroxy-fatty acyl-CoA = a (2E)-enoyl-CoA + H2O

Direction not assertedBalance undeterminableRhea 33767

CDP-N-methylethanolamine + a 1,2-diacyl-sn-glycerol = a 1,2-diacyl-sn-glycero-3-phospho-N-methylethanolamine + CMP + H(+)

Direction not assertedBalance undeterminableRhea 33771

CDP-N,N-dimethylethanolamine + a 1,2-diacyl-sn-glycerol = a 1,2-diacyl-sn-glycero-3-phospho-N,N-dimethylethanolamine + CMP + H(+)

Direction not assertedBalance undeterminableRhea 33775

6-kestotriose + sucrose = 6,6-kestotetraose + beta-D-glucose

Direction not assertedBalancedRhea 33779

1(F)-beta-D-fructosylsucrose + sucrose = 1,6-kestotetraose + beta-D-glucose

Direction not assertedBalancedRhea 33783

3'-ketolactose + H2O = 3-keto-beta-D-galactose + beta-D-glucose

Direction not assertedBalancedRhea 33787

sucrose 6(F)-phosphate + H2O = beta-D-fructose + beta-D-glucose 6-phosphate

Direction not assertedBalancedRhea 33791

sucrose + H2O = beta-D-fructose + alpha-D-glucose

Direction not assertedBalancedRhea 33795

L-histidinol + NAD(+) = L-histidinal + NADH + H(+)

Direction not assertedBalancedRhea 33799

L-histidinal + NAD(+) + H2O = L-histidine + NADH + 2 H(+)

Direction not assertedBalancedRhea 33803

(E)-ferulate + H(+) = 2-methoxy-4-vinylphenol + CO2

Direction not assertedBalancedRhea 33807

3 2,3-dihydroxybenzoate + 3 L-threonine + 3 glycine + 6 ATP = corynebactin + 6 AMP + 6 diphosphate + 3 H2O + 3 H(+)

Direction not assertedBalancedRhea 33811

N-acetyl-beta-D-mannosaminyl-(1->4)-N-acetyl-alpha-D-glucosaminyl di-trans,octa-cis-undecaprenyl diphosphate + CDP-glycerol = 4-O-[(2R)-glycerylphospho]-N-acetyl-beta-D-mannosaminyl-(1->4)-N-acetyl-alpha-D-glucosaminyl di-trans,octa-cis-undecaprenyl diphosphate + CMP + H(+)

Direction not assertedBalancedRhea 33815

3-[(4R)-4-hydroxycyclohexa-1,5-dien-1-yl]-2-oxopropanoate = 3-[(1E,4R)-4-hydroxycyclohex-2-en-1-ylidene]pyruvate

Direction not assertedBalancedRhea 33819

3-(4-hydroxycyclohex-2-en-1-ylidene)pyruvate + NADH + H(+) = tetrahydro-4-hydroxyphenylpyruvate + NAD(+)

Direction not assertedBalancedRhea 33823

ergosterol = vitamin D2

Direction not assertedBalancedRhea 33827

N-hexacosanoyl-(4R)-hydroxysphinganine + H2O = hexacosanoate + (4R)-hydroxysphinganine

Direction not assertedBalancedRhea 33835

2-O,3-dimethylflaviolin + (2E)-geranyl diphosphate + H(+) = 7-O-geranyl-2-O,3-dimethylflaviolin + diphosphate

Direction not assertedBalancedRhea 33839

N-tetracosanoylsphinganine + H2O = tetracosanoate + sphinganine

Direction not assertedBalancedRhea 33843

N-tetracosanoyl-(4R)-hydroxysphinganine + H2O = tetracosanoate + (4R)-hydroxysphinganine

Direction not assertedBalancedRhea 33847

N-tetracosanoylsphinganine-(1D-myo-inositol) + GDP-alpha-D-mannose = mannosyl-alpha-1->6-inositol phospho-N-tetracosanoylsphinganine + GDP + H(+)

Direction not assertedBalancedRhea 33851

an inositol-1-phosphophytoceramide + GDP-alpha-D-mannose = a mannosylinositol-1-phosphophytoceramide + GDP + H(+)

Direction not assertedBalance undeterminableRhea 33855

(2S-3S)-versiconal hemiacetal = versicolorin B + H2O

Direction not assertedBalancedRhea 33859

menaquinone-7 + succinate = menaquinol-7 + fumarate

Direction not assertedBalancedRhea 33863

(S)-2-ureidoglycine + glyoxylate = N-carbamoyl-2-oxoglycine + glycine

Direction not assertedBalancedRhea 33867

(S)-2-ureidoglycine + H2O = urea + glyoxylate + NH4(+)

Direction not assertedBalancedRhea 33871

cholesteryl (9Z-octadecenoate) + H2O = cholesterol + (9Z)-octadecenoate + H(+)

Left to rightBalancedRhea 33875

2-deoxy-scyllo-inosamine + NADP(+) = 3-amino-2,3-dideoxy-scyllo-inosose + NADPH + H(+)

Direction not assertedBalancedRhea 33879

2-deoxy-scyllo-inosamine + NAD(+) = 3-amino-2,3-dideoxy-scyllo-inosose + NADH + H(+)

Direction not assertedBalancedRhea 33883

(-)-secoisolariciresinol + 2 NAD(+) = (-)-matairesinol + 2 NADH + 2 H(+)

Direction not assertedBalancedRhea 33887

chanoclavine-I + NAD(+) = chanoclavine-I aldehyde + NADH + H(+)

Direction not assertedBalancedRhea 33891

trans,octa-cis-decaprenylphospho-beta-D-arabinofuranose + NAD(+) = trans,octa-cis-decaprenylphospho-beta-D-erythro-pentofuranosid-2-ulose + NADH + H(+)

Direction not assertedBalancedRhea 33895

trans,octa-cis-decaprenylphospho-beta-D-ribofuranose + FAD + H(+) = trans,octa-cis-decaprenylphospho-beta-D-erythro-pentofuranosid-2-ulose + FADH2

Direction not assertedBalancedRhea 33899

4-(methylamino)butanoate + O2 + H2O = 4-aminobutanoate + formaldehyde + H2O2

Direction not assertedBalancedRhea 33907

an N-alkylglycine + O2 + H2O = an alkylamine + glyoxylate + H2O2

Direction not assertedBalance undeterminableRhea 33911

4-(methylamino)butanoate + O2 + H2O = succinate semialdehyde + methylamine + H2O2

Direction not assertedBalancedRhea 33915

lanosterol + NADPH + H(+) = 24,25-dihydrolanosterol + NADP(+)

Left to rightBalancedRhea 33919

Page 368 of 629