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CompoundsSubstances with curated findings
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ProteinsTransporters and enzymes
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ReactionsRhea and Human-GEM, by subsystem
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PathwaysReactions grouped under one name
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DiseasesFeatures, genes, and where each sits

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Reference

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Computational infrastructure for human biology, built on a provenance-aware knowledge graph. Findings retain their sources; research and simulation are the next layers.

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A reference for what the literature reports. Not medical advice.

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Index

Reactions

Reactions from Rhea and Human-GEM · Reach

reactions in the graph: 31,435

By source

Rhea18,558
Human-GEM12,877

Inferred

Reference data, not a finding. Evidence key

Filter reactions by equationSource

Reactions

17,551–17,600 of 31,435, by identifier

4-methylsulfanyl-2-oxobutanoate + L-glutamine = 2-oxoglutaramate + L-methionine
Direction not assertedBalancedRhea 30391
alpha-carotene + reduced [NADPH--hemoprotein reductase] + O2 = alpha-cryptoxanthin + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)
Direction not assertedBalance undeterminableRhea 30399
Fe(3+)(out) + L-ascorbate(in) = monodehydro-L-ascorbate radical(in) + Fe(2+)(out) + H(+)
Left to rightBalancedRhea 30403
reduced [plastocyanin] + hnu + oxidized [2Fe-2S]-[ferredoxin] = oxidized [plastocyanin] + reduced [2Fe-2S]-[ferredoxin]
Direction not assertedBalance undeterminableRhea 30407
benzyl alcohol + benzoyl-CoA = benzyl benzoate + CoA
Direction not assertedBalancedRhea 30411
octadecanal + 2 NADPH + O2 + H(+) = heptadecane + formate + 2 NADP(+) + H2O
Direction not assertedBalancedRhea 30415

(2E,6E)-farnesyl diphosphate = (+)-delta-selinene + diphosphate

Direction not assertedBalancedRhea 30423

(2E,6E)-farnesyl diphosphate = (+)-germacrene D + diphosphate

Direction not assertedBalancedRhea 30427

(S)-2,3-epoxysqualene = taraxerol

Direction not assertedBalancedRhea 30431

beta-D-GlcNAc-(1->4)-Mur2Ac(oyl-L-Ala-D-isoglutaminyl-L-Lys-D-Ala-D-Ala)-di-trans,octa-cis-undecaprenyl diphosphate + glycyl-tRNA(Gly) = beta-D-GlcNAc-(1->4)-Mur2Ac(oyl-L-Ala-D-isoglutaminyl-L-Lys-(N(6)-Gly)-D-Ala-D-Ala)-di-trans,octa-cis-undecaprenyl diphosphate + tRNA(Gly) + H(+)

Direction not assertedBalancedRhea 30435

beta-D-GlcNAc-(1->4)-Mur2Ac(oyl-L-Ala-D-isoglutaminyl-L-Lys-(N(6)-Gly)-D-Ala-D-Ala)-di-trans,octa-cis-undecaprenyl diphosphate + 2 glycyl-tRNA(Gly) = MurNAc-L-Ala-D-isoglutaminyl-L-Lys-(N(6)-tri-Gly)-D-Ala-D-Ala-diphospho-di-trans,octa-cis-undecaprenyl-GlcNAc + 2 tRNA(Gly) + 2 H(+)

Direction not assertedBalancedRhea 30439

MurNAc-L-Ala-D-isoglutaminyl-L-Lys-(N(6)-tri-Gly)-D-Ala-D-Ala-diphospho-di-trans,octa-cis-undecaprenyl-GlcNAc + 2 glycyl-tRNA(Gly) = MurNAc-L-Ala-D-isoglutaminyl-L-Lys-(N(6)-penta-Gly)-D-Ala-D-Ala-diphospho-di-trans,octa-cis-undecaprenyl-GlcNAc + 2 tRNA(Gly) + 2 H(+)

Direction not assertedBalancedRhea 30443

3-methylxanthine + NADH + O2 + H(+) = xanthine + formaldehyde + NAD(+) + H2O

Direction not assertedBalancedRhea 30447

(S)-2,3-epoxysqualene = isomultiflorenol

Direction not assertedBalancedRhea 30451

(1S,4aS)-1,4a-dimethyl-1,2,3,4,4a,5,6,8a-octahydronaphthalene + H2O = (-)-geosmin

Direction not assertedBalancedRhea 30455

(1E,4S,5E,7R)-germacra-1(10),5-dien-11-ol = (1S,4aS)-1,4a-dimethyl-1,2,3,4,4a,5,6,8a-octahydronaphthalene + acetone

Direction not assertedBalancedRhea 30459

(2Z,6Z)-farnesyl diphosphate = (+)-alpha-santalene + diphosphate

Direction not assertedBalancedRhea 30463

(2Z,6Z)-farnesyl diphosphate = (+)-endo-beta-bergamotene + diphosphate

Direction not assertedBalancedRhea 30467

(2Z,6Z)-farnesyl diphosphate = (1S,5S,6S)-alpha-bergamotene + diphosphate

Direction not assertedBalancedRhea 30471

oroxylin A 7-O-beta-D-glucuronate + H2O = oroxylin A + D-glucuronate + H(+)

Direction not assertedBalancedRhea 30475

L-isoleucine + reduced [NADPH--hemoprotein reductase] + O2 = N-hydroxy-L-isoleucine + oxidized [NADPH--hemoprotein reductase] + H2O + 2 H(+)

Direction not assertedBalance undeterminableRhea 30479

N-hydroxy-L-isoleucine + reduced [NADPH--hemoprotein reductase] + O2 = N,N-dihydroxy-L-isoleucine + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Direction not assertedBalance undeterminableRhea 30483

N,N-dihydroxy-L-isoleucine + H(+) = (1E,2S)-2-methylbutanal oxime + CO2 + H2O

Direction not assertedBalancedRhea 30487

L-valine + reduced [NADPH--hemoprotein reductase] + O2 = N-hydroxy-L-valine + oxidized [NADPH--hemoprotein reductase] + H2O + 2 H(+)

Direction not assertedBalance undeterminableRhea 30491

N-hydroxy-L-valine + reduced [NADPH--hemoprotein reductase] + O2 = N,N-dihydroxy-L-valine + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Direction not assertedBalance undeterminableRhea 30495

N,N-dihydroxy-L-valine + H(+) = (E)-2-methylpropanal oxime + CO2 + H2O

Direction not assertedBalancedRhea 30499

N-acetyl-L-glutamate 5-semialdehyde + H2O = L-glutamate 5-semialdehyde + acetate

Direction not assertedBalancedRhea 30503

2-demethylmenaquinone-8 + NADH + H(+) = 2-demethylmenaquinol-8 + NAD(+)

Direction not assertedBalancedRhea 30507

2-demethylmenaquinone-8 + NADPH + H(+) = 2-demethylmenaquinol-8 + NADP(+)

Direction not assertedBalancedRhea 30511

S-adenosyl 3-(methylsulfanyl)propylamine + spermidine = thermospermine + S-methyl-5'-thioadenosine + H(+)

Direction not assertedBalancedRhea 30515

phosphoenolpyruvate + GTP + H(+) = enolpyruvoyl-2-diphospho-5'-guanosine + diphosphate

Direction not assertedBalancedRhea 30519

oxidized coenzyme F420-1 + GTP + L-glutamate = oxidized coenzyme F420-2 + GDP + phosphate + H(+)

Direction not assertedBalancedRhea 30523

P(1),P(5)-bis(5'-adenosyl) pentaphosphate + H2O = ADP + ATP + 2 H(+)

Left to rightBalancedRhea 30527

biotinate sulfoxide + NADH + H(+) = biotin + NAD(+) + H2O

Direction not assertedBalancedRhea 30531

biotinate sulfoxide + NADPH + H(+) = biotin + NADP(+) + H2O

Direction not assertedBalancedRhea 30535

(R)-carnitinyl-CoA = (S)-carnitinyl-CoA

Direction not assertedBalancedRhea 30539

(S)-carnitine + ATP + CoA = (S)-carnitinyl-CoA + ADP + phosphate

Direction not assertedBalancedRhea 30543

(3S)-hydroxyhexanoyl-CoA = (2E)-hexenoyl-CoA + H2O

Right to leftBalancedRhea 30547

beta-D-glucose + acetyl-CoA = 6-O-acetyl-beta-D-glucose + CoA

Direction not assertedBalancedRhea 30551

oxidized coenzyme F420-0 + GTP + L-glutamate = oxidized coenzyme F420-1 + GDP + phosphate + H(+)

Direction not assertedBalancedRhea 30555

GTP + H2O = guanosine + triphosphate + H(+)

Direction not assertedBalancedRhea 30559

dimethylallyl diphosphate + L-tryptophan = 7-(3-methylbut-2-enyl)-L-tryptophan + diphosphate

Direction not assertedBalancedRhea 30563

5,6,7,8-tetrahydromethanopterin + L-glutamate + ATP = 5,6,7,8-tetrahydrosarcinapterin + ADP + phosphate + H(+)

Direction not assertedBalancedRhea 30567

3 2,3-dihydroxybenzoate + 3 L-serine + 6 ATP = enterobactin + 6 AMP + 6 diphosphate + 4 H(+)

Direction not assertedBalancedRhea 30571

protoporphyrinogen IX + 3 menaquinone-8 = protoporphyrin IX + 3 menaquinol-8

Direction not assertedBalancedRhea 30575

O-phospho-L-threonine + H2O = L-threonine + phosphate

Direction not assertedBalancedRhea 30579

2-demethylmenaquinol-8 + trimethylamine N-oxide + H(+) = 2-demethylmenaquinone-8 + trimethylamine + H2O

Direction not assertedBalancedRhea 30583

2-demethylmenaquinol-8 + dimethyl sulfoxide = 2-demethylmenaquinone-8 + dimethyl sulfide + H2O

Direction not assertedBalancedRhea 30587

tyramine + O2 + H2O = (4-hydroxyphenyl)acetaldehyde + H2O2 + NH4(+)

Left to rightBalancedRhea 30591

4-hydroxyphenylacetate + FADH2 + O2 = 3,4-dihydroxyphenylacetate + FAD + H2O + H(+)

Direction not assertedBalancedRhea 30595

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