Skip to content

Reference

Evidence

CompoundsSubstances with curated findings
OutcomesMeasured endpoints
ProteinsTransporters and enzymes
InteractionsPairs that share biology
PapersEvery paper a finding cites
ArticlesReadings of the evidence

Chemistry

ReactionsRhea and Human-GEM, by subsystem
ReachWhat a compound can become

Reference layer

PathwaysReactions grouped under one name
ProcessesWhat proteins are annotated as doing
AnatomyTissues, by what is expressed there
Cell typesCells, by what is expressed there
OrganismsSpecies a compound is prepared from
MaterialsSubstances that are not one molecule
AssessmentsRegulatory determinations, transcribed
DiseasesFeatures, genes, and where each sits

Atlas Graph Twin Access

Search the graph

Reference

Evidence

Compounds
Outcomes
Proteins
Interactions
Papers
Articles

Chemistry

Reactions
Reach

Reference layer

Pathways
Processes
Anatomy
Cell types
Organisms
Materials
Assessments
Diseases

Atlas Graph Twin Access

Loading the page.

Catalyst

Computational infrastructure for human biology, built on a provenance-aware knowledge graph. Findings retain their sources; research and simulation are the next layers.

The graph

Compounds
Outcomes
Proteins
Atlas
Interactions
Papers
Articles
Graph
Search

Reference layer

Pathways
Processes
Anatomy
Cell types
Organisms
Materials
Assessments
Diseases
Reactions
Reach

How it works

Mission
Method
Twin
How to read the evidence
Sources and licences

Build on it

Access
In your assistant
For agents
Query the graph
Bulk export

A reference for what the literature reports. Not medical advice.

© 2026 CatalystPrivacy TermsReference data under the licences listed on the attribution page.

Index

Reactions

Reactions from Rhea and Human-GEM · Reach

reactions in the graph: 31,435

By source

Rhea18,558
Human-GEM12,877

Inferred

Reference data, not a finding. Evidence key

Filter reactions by equationSource

Reactions

17,401–17,450 of 31,435, by identifier

alpha-D-ribose 1-phosphate + ATP = alpha-D-ribose 1,5-bisphosphate + ADP + H(+)
Direction not assertedBalancedRhea 29775
L-methionine(out) + ATP + H2O = L-methionine(in) + ADP + phosphate + H(+)
Direction not assertedBalancedTransportRhea 29779
L-cysteine(in) + ATP + H2O = L-cysteine(out) + ADP + phosphate + H(+)
Direction not assertedBalancedTransportRhea 29783
glutathione(in) + ATP + H2O = glutathione(out) + ADP + phosphate + H(+)
Direction not assertedBalancedTransportRhea 29787
glutathione(out) + ATP + H2O = glutathione(in) + ADP + phosphate + H(+)
Direction not assertedBalancedTransportRhea 29791
Zn(2+)(out) + ATP(in) + H2O(in) = Zn(2+)(in) + ADP(in) + phosphate(in) + H(+)(in)
Direction not assertedBalancedTransportRhea 29795

D-allose(out) + ATP + H2O = D-allose(in) + ADP + phosphate + H(+)

Direction not assertedBalancedTransportRhea 29799

L-valine(out) + ATP + H2O = L-valine(in) + ADP + phosphate + H(+)

Direction not assertedBalancedTransportRhea 29803

L-leucine(out) + ATP + H2O = L-leucine(in) + ADP + phosphate + H(+)

Direction not assertedBalancedTransportRhea 29807

thiamine(out) + ATP + H2O = thiamine(in) + ADP + phosphate + H(+)

Direction not assertedBalancedTransportRhea 29811

L-proline(out) + ATP + H2O = L-proline(in) + ADP + phosphate + H(+)

Direction not assertedBalancedTransportRhea 29815

L-isoleucine(out) + ATP + H2O = L-isoleucine(in) + ADP + phosphate + H(+)

Direction not assertedBalancedTransportRhea 29819

chloride(in) = chloride(out)

Right to leftBalancedTransportRhea 29823

Mg(2+)(in) = Mg(2+)(out)

Direction not assertedBalancedTransportRhea 29827

Ni(2+)(in) = Ni(2+)(out)

Direction not assertedBalancedTransportRhea 29831

D-galactonate(in) + H(+)(in) = D-galactonate(out) + H(+)(out)

Direction not assertedBalancedTransportRhea 29835

L-idonate + NADP(+) = 2-dehydro-L-idonate + NADPH + H(+)

Direction not assertedBalancedRhea 29839

propanoate + ATP + CoA = propanoyl-CoA + ADP + phosphate

Direction not assertedBalancedRhea 29843

(2E)-tetradecenoyl-CoA = (3Z)-tetradecenoyl-CoA

Right to leftBalancedRhea 29847

UDP-N-acetyl-alpha-D-galactosamine + H2O = N-acetyl-alpha-D-galactosamine 1-phosphate + UMP + 2 H(+)

Direction not assertedBalancedRhea 29851

L-alanyl-gamma-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanine + H2O = L-alanyl-gamma-D-glutamyl-meso-2,6-diaminopimelate + D-alanine

Direction not assertedBalancedRhea 29855

5'-deoxyadenosine + H2O = 5-deoxy-D-ribose + adenine

Direction not assertedBalancedRhea 29859

GTP + AMP = GDP + ADP

Direction not assertedBalancedRhea 29863

ITP + AMP = IDP + ADP

Direction not assertedBalancedRhea 29867

thiosulfate(out) + ATP + H2O = thiosulfate(in) + ADP + phosphate + H(+)

Direction not assertedBalancedTransportRhea 29871

sn-glycero-3-phospho-L-serine + H2O = sn-glycerol 3-phosphate + L-serine + H(+)

Direction not assertedBalancedRhea 29875

L-arginine(out) + ATP + H2O = L-arginine(in) + ADP + phosphate + H(+)

Direction not assertedBalancedTransportRhea 29879

L-ornithine(out) + ATP + H2O = L-ornithine(in) + ADP + phosphate + H(+)

Direction not assertedBalancedTransportRhea 29883

L-lysine(out) + ATP + H2O = L-lysine(in) + ADP + phosphate + H(+)

Direction not assertedBalancedTransportRhea 29887

L-histidine(out) + ATP + H2O = L-histidine(in) + ADP + phosphate + H(+)

Direction not assertedBalancedTransportRhea 29891

L-glutamine(out) + ATP + H2O = L-glutamine(in) + ADP + phosphate + H(+)

Direction not assertedBalancedTransportRhea 29895

D-xylose(out) + ATP + H2O = D-xylose(in) + ADP + phosphate + H(+)

Direction not assertedBalancedTransportRhea 29899

D-ribose(out) + ATP + H2O = D-ribose(in) + ADP + phosphate + H(+)

Direction not assertedBalancedTransportRhea 29903

sn-glycero-3-phospho-(1'-rac-glycerol) + H2O = sn-glycerol 3-phosphate + glycerol + H(+)

Direction not assertedBalancedRhea 29907

L-alpha-D-Hep-(1->3)-L-alpha-D-Hep-(1->5)-[alpha-Kdo-(2->4)]-alpha-Kdo-(2->6)-lipid A (E. coli) + UDP-alpha-D-glucose = alpha-D-Glc-(1->3)-L-alpha-D-Hep-(1->3)-L-alpha-D-Hep-(1->5)-[alpha-Kdo-(2->4)]-alpha-Kdo-(2->6)-lipid A + UDP + H(+)

Direction not assertedBalancedRhea 29915

alpha-D-Glc-(1->3)-L-alpha-D-Hep-(1->3)-L-alpha-D-Hep-(1->5)-[alpha-Kdo-(2->4)]-alpha-Kdo-(2->6)-lipid A + ATP = alpha-D-Glc-(1->3)-L-alpha-D-Hep-(1->3)-4-O-PO3(2-)-L-alpha-D-Hep-(1->5)-[alpha-Kdo-(2->4)]-alpha-Kdo-(2->6)-lipid A + ADP + H(+)

Direction not assertedBalancedRhea 29919

alpha-D-Glc-(1->3)-L-alpha-D-Hep-(1->3)-4-O-PO3(2-)-L-alpha-D-Hep-(1->5)-[alpha-Kdo-(2->4)]-alpha-Kdo-(2->6)-lipid A + ADP-L-glycero-beta-D-manno-heptose = alpha-D-Glc-(1->3)-[L-alpha-D-Hep-(1->7)]-L-alpha-D-Hep-(1->3)-4-O-PO3(2-)-L-alpha-D-Hep-(1->5)-[alpha-Kdo-(2->4)]-alpha-Kdo-(2->6)-lipid A + ADP + H(+)

Direction not assertedBalancedRhea 29923

(R)-pantothenate(in) + Na(+)(in) = (R)-pantothenate(out) + Na(+)(out)

Direction not assertedBalancedTransportRhea 29927

alpha-D-Glc-(1->3)-[L-alpha-D-Hep-(1->7)]-L-alpha-D-Hep-(1->3)-4-O-PO3(2-)-L-alpha-D-Hep-(1->5)-[alpha-Kdo-(2->4)]-alpha-Kdo-(2->6)-lipid A + ATP = alpha-D-Glc-(1->3)-[L-alpha-D-Hep-(1->7)]-4-O-PO3(2-)-L-alpha-D-Hep-(1->3)-4-O-PO3(2-)-L-alpha-D-Hep-(1->5)-[alpha-Kdo-(2->4)]-alpha-Kdo-(2->6)-lipid A + ADP + H(+)

Direction not assertedBalancedRhea 29931

cytosine(in) + H(+)(in) = cytosine(out) + H(+)(out)

Direction not assertedBalancedTransportRhea 29935

phosphate(in) + H(+)(in) = phosphate(out) + H(+)(out)

Right to leftBalancedTransportRhea 29939

2-dehydro-3-deoxy-D-gluconate(in) + H(+)(in) = 2-dehydro-3-deoxy-D-gluconate(out) + H(+)(out)

Direction not assertedBalancedTransportRhea 29943

L-rhamnopyranose(in) + H(+)(in) = L-rhamnopyranose(out) + H(+)(out)

Direction not assertedBalancedTransportRhea 29947

uridine(in) + H(+)(in) = uridine(out) + H(+)(out)

Direction not assertedBalancedTransportRhea 29951

thymidine(in) + H(+)(in) = thymidine(out) + H(+)(out)

Direction not assertedBalancedTransportRhea 29955

alpha-D-Glc-(1->3)-[L-alpha-D-Hep-(1->7)]-4-O-PO3(2-)-L-alpha-D-Hep-(1->3)-4-O-PO3(2-)-L-alpha-D-Hep-(1->5)-[alpha-Kdo-(2->4)]-alpha-Kdo-(2->6)-lipid A + UDP-alpha-D-galactose = alpha-D-Gal-(1->6)-alpha-D-Glc-(1->3)-[L-alpha-D-Hep-(1->7)]-4-O-PO3(2-)-L-alpha-D-Hep-(1->3)-4-O-PO3(2-)-L-alpha-D-Hep-(1->5)-[alpha-Kdo-(2->4)]-alpha-Kdo-(2->6)-lipid A + UDP + H(+)

Direction not assertedBalancedRhea 29959

inosine(in) + H(+)(in) = inosine(out) + H(+)(out)

Direction not assertedBalancedTransportRhea 29963

2'-deoxyuridine(in) + H(+)(in) = 2'-deoxyuridine(out) + H(+)(out)

Direction not assertedBalancedTransportRhea 29967

2'-deoxyinosine(in) + H(+)(in) = 2'-deoxyinosine(out) + H(+)(out)

Direction not assertedBalancedTransportRhea 29971

2'-deoxycytidine(in) + H(+)(in) = 2'-deoxycytidine(out) + H(+)(out)

Direction not assertedBalancedTransportRhea 29975

Page 349 of 629