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Evidence

CompoundsSubstances with curated findings
OutcomesMeasured endpoints
ProteinsTransporters and enzymes
InteractionsPairs that share biology
PapersEvery paper a finding cites
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ReactionsRhea and Human-GEM, by subsystem
ReachWhat a compound can become

Reference layer

PathwaysReactions grouped under one name
ProcessesWhat proteins are annotated as doing
AnatomyTissues, by what is expressed there
Cell typesCells, by what is expressed there
OrganismsSpecies a compound is prepared from
MaterialsSubstances that are not one molecule
AssessmentsRegulatory determinations, transcribed
DiseasesFeatures, genes, and where each sits

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Reference

Evidence

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Proteins
Interactions
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Reactions
Reach

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Diseases

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Computational infrastructure for human biology, built on a provenance-aware knowledge graph. Findings retain their sources; research and simulation are the next layers.

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A reference for what the literature reports. Not medical advice.

© 2026 CatalystPrivacy TermsReference data under the licences listed on the attribution page.

Index

Reactions

Reactions from Rhea and Human-GEM · Reach

reactions in the graph: 31,435

By source

Rhea18,558
Human-GEM12,877

Inferred

Reference data, not a finding. Evidence key

Filter reactions by equationSource

Reactions

17,351–17,400 of 31,435, by identifier

UDP-alpha-D-glucuronate + H2O = 1-phospho-alpha-D-glucuronate + UMP + 2 H(+)
Direction not assertedBalancedRhea 29559
UDP-N-acetyl-alpha-D-muramate + L-alanyl-gamma-D-glutamyl-meso-2,6-diaminopimelate + ATP = UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-gamma-D-glutamyl-meso-2,6-diaminopimelate + ADP + phosphate + H(+)
Direction not assertedBalancedRhea 29563
2 chloride(in) + H(+)(out) = 2 chloride(out) + H(+)(in)
Left to rightBalancedTransportRhea 29567
L-idonate(in) + H(+)(in) = L-idonate(out) + H(+)(out)
Direction not assertedBalancedTransportRhea 29571
L-serine(in) + Na(+)(in) = L-serine(out) + Na(+)(out)
Right to leftBalancedTransportRhea 29575
Fe(2+)(in) + H(+)(in) = Fe(2+)(out) + H(+)(out)
ReversibleBalancedTransportRhea 29579

guanosine(in) + H(+)(out) = guanosine(out) + H(+)(in)

Direction not assertedBalancedTransportRhea 29583

4-carboxy-2-hydroxymuconate semialdehyde hemiacetal + NADP(+) = 2-oxo-2H-pyran-4,6-dicarboxylate + NADPH + H(+)

Direction not assertedBalancedRhea 29587

2-hydroxyethane-1-sulfonate + NADP(+) = sulfoacetaldehyde + NADPH + H(+)

Direction not assertedBalancedRhea 29591

sulfoacetaldehyde + NADP(+) + CoA = sulfoacetyl-CoA + NADPH + H(+)

Direction not assertedBalancedRhea 29595

monacolin L carboxylate + reduced [NADPH--hemoprotein reductase] + O2 = monacolin J carboxylate + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Direction not assertedBalance undeterminableRhea 29599

oxidized 2[4Fe-4S]-[ferredoxin] + benzoyl-CoA + H2O = 4-hydroxybenzoyl-CoA + reduced 2[4Fe-4S]-[ferredoxin] + 2 H(+)

Direction not assertedBalance undeterminableRhea 29603

nitrous oxide + NAD(+) + H2O = 2 nitric oxide + NADH + H(+)

Direction not assertedBalancedRhea 29607

nitrous oxide + NADP(+) + H2O = 2 nitric oxide + NADPH + H(+)

Direction not assertedBalancedRhea 29611

alpha-maltotriose + beta-maltose = alpha-maltotetraose + beta-D-glucose

Direction not assertedBalancedRhea 29615

alpha-maltotetraose + beta-maltose = alpha-maltopentaose + beta-D-glucose

Direction not assertedBalancedRhea 29619

alpha-maltopentaose + beta-maltose = alpha-maltohexaose + beta-D-glucose

Direction not assertedBalancedRhea 29623

alpha-maltohexaose + beta-maltose = alpha-maltoheptaose + beta-D-glucose

Direction not assertedBalancedRhea 29627

D-maltotetraose + H2O = D-maltotriose + alpha-D-glucose

Left to rightBalancedRhea 29631

D-maltopentaose + H2O = D-maltotetraose + alpha-D-glucose

Left to rightBalancedRhea 29635

D-maltohexaose + H2O = D-maltopentaose + alpha-D-glucose

Left to rightBalancedRhea 29639

D-maltoheptaose + H2O = D-maltohexaose + alpha-D-glucose

Left to rightBalancedRhea 29643

alpha-maltopentaose + phosphate = alpha-maltotetraose + alpha-D-glucose 1-phosphate

Direction not assertedBalancedRhea 29647

agmatine(in) + L-arginine(out) = agmatine(out) + L-arginine(in)

Direction not assertedBalancedTransportRhea 29651

L-cysteine(in) = L-cysteine(out)

Left to rightBalancedTransportRhea 29655

O-acetyl-L-serine(in) = O-acetyl-L-serine(out)

Direction not assertedBalancedTransportRhea 29659

xanthine(in) + H(+)(in) = xanthine(out) + H(+)(out)

Direction not assertedBalancedTransportRhea 29663

H2O(in) = H2O(out)

Direction not assertedBalancedTransportRhea 29667

Ca(2+)(in) = Ca(2+)(out)

Right to leftBalancedTransportRhea 29671

glycerol(in) = glycerol(out)

Direction not assertedBalancedTransportRhea 29675

formate(in) = formate(out)

Direction not assertedBalancedTransportRhea 29679

alpha-maltohexaose + phosphate = alpha-maltopentaose + alpha-D-glucose 1-phosphate

Direction not assertedBalancedRhea 29683

alpha-maltoheptaose + phosphate = alpha-maltohexaose + alpha-D-glucose 1-phosphate

Direction not assertedBalancedRhea 29687

alpha-maltotetraose + phosphate = alpha-maltotriose + alpha-D-glucose 1-phosphate

Direction not assertedBalancedRhea 29691

dimethyl sulfoxide(in) = dimethyl sulfoxide(out)

Direction not assertedBalancedTransportRhea 29699

L-valine(in) = L-valine(out)

Direction not assertedBalancedTransportRhea 29703

cadaverine(in) + H(+)(in) = cadaverine(out) + H(+)(out)

Direction not assertedBalancedTransportRhea 29711

2-hydroxyethane-1-sulfonate + FMNH2 + O2 = glycolaldehyde + FMN + sulfite + H2O + 2 H(+)

Direction not assertedBalancedRhea 29715

glyoxylate(in) = glyoxylate(out)

Direction not assertedBalancedTransportRhea 29723

ethane-1-sulfonate + FMNH2 + O2 = acetaldehyde + FMN + sulfite + H2O + 2 H(+)

Direction not assertedBalancedRhea 29727

beta-maltose(in) = beta-maltose(out)

Direction not assertedBalancedTransportRhea 29731

butane-1-sulfonate + FMNH2 + O2 = butanal + FMN + sulfite + H2O + 2 H(+)

Direction not assertedBalancedRhea 29735

2-phenylethylamine(in) = 2-phenylethylamine(out)

Direction not assertedBalancedTransportRhea 29743

3-phenylpropanoate(in) = 3-phenylpropanoate(out)

Direction not assertedBalancedTransportRhea 29747

acetoacetate(in) = acetoacetate(out)

Direction not assertedBalancedTransportRhea 29751

(R)-lipoate(in) = (R)-lipoate(out)

Direction not assertedBalancedTransportRhea 29755

octanoate(in) = octanoate(out)

Direction not assertedBalancedTransportRhea 29759

L-alanyl-gamma-D-glutamyl-meso-2,6-diaminopimelate(out) + ATP + H2O = L-alanyl-gamma-D-glutamyl-meso-2,6-diaminopimelate(in) + ADP + phosphate + H(+)

Direction not assertedBalancedTransportRhea 29763

D-methionine(out) + ATP + H2O = D-methionine(in) + ADP + phosphate + H(+)

Direction not assertedBalancedTransportRhea 29767

arsenate(in) + ATP + H2O = arsenate(out) + ADP + phosphate + H(+)

Direction not assertedBalancedTransportRhea 29771

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