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Reference

Evidence

CompoundsSubstances with curated findings
OutcomesMeasured endpoints
ProteinsTransporters and enzymes
InteractionsPairs that share biology
PapersEvery paper a finding cites
ArticlesReadings of the evidence

Chemistry

ReactionsRhea and Human-GEM, by subsystem
ReachWhat a compound can become

Reference layer

PathwaysReactions grouped under one name
ProcessesWhat proteins are annotated as doing
AnatomyTissues, by what is expressed there
Cell typesCells, by what is expressed there
OrganismsSpecies a compound is prepared from
MaterialsSubstances that are not one molecule
AssessmentsRegulatory determinations, transcribed
DiseasesFeatures, genes, and where each sits

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Reference

Evidence

Compounds
Outcomes
Proteins
Interactions
Papers
Articles

Chemistry

Reactions
Reach

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Pathways
Processes
Anatomy
Cell types
Organisms
Materials
Assessments
Diseases

Atlas Graph Twin Access

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Catalyst

Computational infrastructure for human biology, built on a provenance-aware knowledge graph. Findings retain their sources; research and simulation are the next layers.

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A reference for what the literature reports. Not medical advice.

© 2026 CatalystPrivacy TermsReference data under the licences listed on the attribution page.

Index

Reactions

Reactions from Rhea and Human-GEM · Reach

reactions in the graph: 31,435

By source

Rhea18,558
Human-GEM12,877

Inferred

Reference data, not a finding. Evidence key

Filter reactions by equationSource

Reactions

17,201–17,250 of 31,435, by identifier

L-arabinose(in) + H(+)(in) = L-arabinose(out) + H(+)(out)
Direction not assertedBalancedTransportRhea 28951
aldehydo-D-glucuronate(in) + H(+)(in) = aldehydo-D-glucuronate(out) + H(+)(out)
Direction not assertedBalancedTransportRhea 28955
D-xylose(in) + H(+)(in) = D-xylose(out) + H(+)(out)
Direction not assertedBalancedTransportRhea 28959
L-proline(out) + H(+)(out) = L-proline(in) + H(+)(in)
Direction not assertedBalancedTransportRhea 28963
L-proline(in) + Na(+)(in) = L-proline(out) + Na(+)(out)
Right to leftBalancedTransportRhea 28967
shikimate(in) + H(+)(in) = shikimate(out) + H(+)(out)
Direction not assertedBalancedTransportRhea 28971
L-asparagine(in) + H(+)(out) = L-asparagine(out) + H(+)(in)

Direction not assertedBalancedTransportRhea 28975

nitrite(in) + H(+)(out) = nitrite(out) + H(+)(in)

Direction not assertedBalancedTransportRhea 28979

nitrite(in) = nitrite(out)

Direction not assertedBalancedTransportRhea 28983

N-acetylneuraminate(in) + H(+)(in) = N-acetylneuraminate(out) + H(+)(out)

Right to leftBalancedTransportRhea 28987

N-acetylneuraminate(in) = N-acetylneuraminate(out)

Direction not assertedBalancedTransportRhea 28991

L-threonine(in) + H(+)(out) = L-threonine(out) + H(+)(in)

Direction not assertedBalancedTransportRhea 28995

homoserine lactone(in) + H(+)(out) = homoserine lactone(out) + H(+)(in)

Direction not assertedBalancedTransportRhea 28999

L-homoserine(in) + H(+)(out) = L-homoserine(out) + H(+)(in)

Direction not assertedBalancedTransportRhea 29003

Mn(2+)(in) + H(+)(in) = Mn(2+)(out) + H(+)(out)

ReversibleBalancedTransportRhea 29007

2-oxoglutarate(in) + H(+)(in) = 2-oxoglutarate(out) + H(+)(out)

Direction not assertedBalancedTransportRhea 29011

sn-glycerol 3-phosphate(in) + phosphate(out) = sn-glycerol 3-phosphate(out) + phosphate(in)

Direction not assertedBalancedTransportRhea 29015

D-galactose(in) + H(+)(in) = D-galactose(out) + H(+)(out)

Direction not assertedBalancedTransportRhea 29019

L-fucose(in) + H(+)(in) = L-fucose(out) + H(+)(out)

Direction not assertedBalancedTransportRhea 29023

L-glutamate(in) + 2 H(+)(in) = L-glutamate(out) + 2 H(+)(out)

Direction not assertedBalancedTransportRhea 29027

L-glutamate(in) + 2 Na(+)(in) = L-glutamate(out) + 2 Na(+)(out)

Direction not assertedBalancedTransportRhea 29031

L-glutamate(out) + ATP + H2O = L-glutamate(in) + ADP + phosphate + H(+)

Direction not assertedBalancedTransportRhea 29035

L-aspartate(out) + ATP + H2O = L-aspartate(in) + ADP + phosphate + H(+)

Direction not assertedBalancedTransportRhea 29039

dUMP + (6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + NADPH + H(+) = dTMP + (6S)-5,6,7,8-tetrahydrofolate + NADP(+)

Direction not assertedBalancedRhea 29043

H2 + a menaquinone + 2 H(+)(in) = a menaquinol + 2 H(+)(out)

Direction not assertedBalance undeterminableTransportRhea 29047

menaquinone-8 + H2 + 2 H(+)(in) = menaquinol-8 + 2 H(+)(out)

Direction not assertedBalancedTransportRhea 29051

H2 + a ubiquinone + 2 H(+)(in) = a ubiquinol + 2 H(+)(out)

Direction not assertedBalance undeterminableTransportRhea 29055

ubiquinone-8 + H2 + 2 H(+)(in) = ubiquinol-8 + 2 H(+)(out)

Direction not assertedBalancedTransportRhea 29059

a menaquinone + formate + H(+) = a menaquinol + CO2

Direction not assertedBalance undeterminableRhea 29063

menaquinone-8 + formate + H(+) = menaquinol-8 + CO2

Direction not assertedBalancedRhea 29067

a ubiquinone + formate + H(+) = a ubiquinol + CO2

Direction not assertedBalance undeterminableRhea 29071

ubiquinone-8 + formate(out) + 2 H(+)(in) = ubiquinol-8 + CO2(out) + H(+)(out)

Direction not assertedBalancedTransportRhea 29075

ubiquinone-8 + (R)-lactate = ubiquinol-8 + pyruvate

Direction not assertedBalancedRhea 29079

ubiquinone-8 + (S)-malate = ubiquinol-8 + oxaloacetate

Direction not assertedBalancedRhea 29083

menaquinone-8 + (S)-malate = menaquinol-8 + oxaloacetate

Direction not assertedBalancedRhea 29087

a ubiquinone + NADH + 5 H(+)(in) = a ubiquinol + NAD(+) + 4 H(+)(out)

Left to rightBalance undeterminableTransportRhea 29091

ubiquinone-8 + NADH + 5 H(+)(in) = ubiquinol-8 + NAD(+) + 4 H(+)(out)

Direction not assertedBalancedTransportRhea 29095

a menaquinone + NADH + 5 H(+)(in) = a menaquinol + NAD(+) + 4 H(+)(out)

Direction not assertedBalance undeterminableTransportRhea 29099

menaquinone-8 + NADH + 5 H(+)(in) = menaquinol-8 + NAD(+) + 4 H(+)(out)

Direction not assertedBalancedTransportRhea 29103

ubiquinone-8 + NADH + H(+) = ubiquinol-8 + NAD(+)

Direction not assertedBalancedRhea 29107

ubiquinone-8 + NADPH + H(+) = ubiquinol-8 + NADP(+)

Direction not assertedBalancedRhea 29111

menaquinone-8 + NADPH + H(+) = menaquinol-8 + NADP(+)

Direction not assertedBalancedRhea 29115

a ubiquinol + nitrate = a ubiquinone + nitrite + H2O

Direction not assertedBalance undeterminableRhea 29119

ubiquinol-8(in) + nitrate(out) = ubiquinone-8(in) + nitrite(out) + H2O(out)

Direction not assertedBalancedRhea 29123

a menaquinol + nitrate = a menaquinone + nitrite + H2O

Direction not assertedBalance undeterminableRhea 29127

menaquinol-8 + nitrate = menaquinone-8 + nitrite + H2O

Direction not assertedBalancedRhea 29131

a menaquinol + nitrate + 2 H(+)(in) = a menaquinone + nitrite + H2O + 2 H(+)(out)

Direction not assertedBalance undeterminableTransportRhea 29135

menaquinol-8 + nitrate + 2 H(+)(in) = menaquinone-8 + nitrite + H2O + 2 H(+)(out)

Direction not assertedBalancedTransportRhea 29139

a ubiquinol + nitrate + 2 H(+)(in) = a ubiquinone + nitrite + H2O + 2 H(+)(out)

Direction not assertedBalance undeterminableTransportRhea 29143

ubiquinol-8 + nitrate + 2 H(+)(in) = ubiquinone-8 + nitrite + H2O + 2 H(+)(out)

Direction not assertedBalancedTransportRhea 29147

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