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Reference

Evidence

CompoundsSubstances with curated findings
OutcomesMeasured endpoints
ProteinsTransporters and enzymes
InteractionsPairs that share biology
PapersEvery paper a finding cites
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Chemistry

ReactionsRhea and Human-GEM, by subsystem
ReachWhat a compound can become

Reference layer

PathwaysReactions grouped under one name
ProcessesWhat proteins are annotated as doing
AnatomyTissues, by what is expressed there
Cell typesCells, by what is expressed there
OrganismsSpecies a compound is prepared from
MaterialsSubstances that are not one molecule
AssessmentsRegulatory determinations, transcribed
DiseasesFeatures, genes, and where each sits

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Reference

Evidence

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Proteins
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Reactions
Reach

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Cell types
Organisms
Materials
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Diseases

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Computational infrastructure for human biology, built on a provenance-aware knowledge graph. Findings retain their sources; research and simulation are the next layers.

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A reference for what the literature reports. Not medical advice.

© 2026 CatalystPrivacy TermsReference data under the licences listed on the attribution page.

Index

Reactions

Reactions from Rhea and Human-GEM · Reach

reactions in the graph: 31,435

By source

Rhea18,558
Human-GEM12,877

Inferred

Reference data, not a finding. Evidence key

Filter reactions by equationSource

Reactions

17,251–17,300 of 31,435, by identifier

3 a ubiquinol(in) + nitrite(out) + 2 H(+)(out) = 3 a ubiquinone(in) + NH4(+)(out) + 2 H2O(out)
Direction not assertedBalance undeterminableRhea 29151
3 ubiquinol-8(in) + nitrite(out) + 2 H(+)(out) = 3 ubiquinone-8(in) + NH4(+)(out) + 2 H2O(out)
Direction not assertedBalancedRhea 29155
3 a menaquinol(in) + nitrite(out) + 2 H(+)(out) = 3 a menaquinone(in) + NH4(+)(out) + 2 H2O(out)
Direction not assertedBalance undeterminableRhea 29159
3 menaquinol-8(in) + nitrite(out) + 2 H(+)(out) = 3 menaquinone-8(in) + NH4(+)(out) + 2 H2O(out)
Direction not assertedBalancedRhea 29163
a ubiquinol + 2 O2 = 2 superoxide + a ubiquinone + 2 H(+)
Direction not assertedBalance undeterminableRhea 29171
ubiquinol-8 + 2 O2 = 2 superoxide + ubiquinone-8 + 2 H(+)
Direction not assertedBalancedRhea 29175

a menaquinol + 2 O2 = 2 superoxide + a menaquinone + 2 H(+)

Direction not assertedBalance undeterminableRhea 29179

menaquinol-8 + 2 O2 = 2 superoxide + menaquinone-8 + 2 H(+)

Direction not assertedBalancedRhea 29183

ubiquinone-8 + succinate = ubiquinol-8 + fumarate

Direction not assertedBalancedRhea 29187

menaquinone-8 + L-aspartate = iminosuccinate + menaquinol-8

Direction not assertedBalancedRhea 29191

(S)-dihydroorotate + a menaquinone = orotate + a menaquinol

Direction not assertedBalance undeterminableRhea 29195

(S)-dihydroorotate + menaquinone-8 = orotate + menaquinol-8

Direction not assertedBalancedRhea 29199

dimethyl sulfoxide + menaquinol-8 = dimethyl sulfide + menaquinone-8 + H2O

Direction not assertedBalancedRhea 29203

dimethyl sulfoxide(out) + a menaquinol(in) = dimethyl sulfide(out) + a menaquinone(in) + H2O(out)

Direction not assertedBalance undeterminableRhea 29207

inosine(in) + H(+)(out) = inosine(out) + H(+)(in)

Direction not assertedBalancedTransportRhea 29211

menaquinol-8 + fumarate = menaquinone-8 + succinate

Direction not assertedBalancedRhea 29215

a menaquinone + sn-glycerol 3-phosphate = a menaquinol + dihydroxyacetone phosphate

Direction not assertedBalance undeterminableRhea 29219

menaquinone-8 + sn-glycerol 3-phosphate = menaquinol-8 + dihydroxyacetone phosphate

Direction not assertedBalancedRhea 29223

indole(in) + H(+)(in) = indole(out) + H(+)(out)

Direction not assertedBalancedTransportRhea 29227

cyanate(in) = cyanate(out)

Direction not assertedBalancedTransportRhea 29231

a menaquinone + NADH + H(+) = a menaquinol + NAD(+)

Direction not assertedBalance undeterminableRhea 29235

uracil(in) + H(+)(in) = uracil(out) + H(+)(out)

Direction not assertedBalancedTransportRhea 29239

menaquinone-8 + NADH + H(+) = menaquinol-8 + NAD(+)

Direction not assertedBalancedRhea 29243

2 Na(+)(in) + 3 H(+)(out) = 2 Na(+)(out) + 3 H(+)(in)

Direction not assertedBalancedTransportRhea 29247

Na(+)(in) + 2 H(+)(out) = Na(+)(out) + 2 H(+)(in)

Direction not assertedBalancedTransportRhea 29251

Ca(2+)(in) + Na(+)(out) = Ca(2+)(out) + Na(+)(in)

Direction not assertedBalancedTransportRhea 29255

(2R,3R)-tartrate(out) + succinate(in) = (2R,3R)-tartrate(in) + succinate(out)

Direction not assertedBalancedTransportRhea 29259

L-leucine(in) + Na(+)(in) = L-leucine(out) + Na(+)(out)

Right to leftBalancedTransportRhea 29263

L-valine(in) + Na(+)(in) = L-valine(out) + Na(+)(out)

Direction not assertedBalancedTransportRhea 29267

trimethylamine N-oxide + a menaquinol + H(+) = trimethylamine + a menaquinone + H2O

Direction not assertedBalance undeterminableRhea 29271

L-isoleucine(in) + Na(+)(in) = L-isoleucine(out) + Na(+)(out)

Direction not assertedBalancedTransportRhea 29275

trimethylamine N-oxide + menaquinol-8 + H(+) = trimethylamine + menaquinone-8 + H2O

Direction not assertedBalancedRhea 29279

L-alanine(in) + Na(+)(in) = L-alanine(out) + Na(+)(out)

Right to leftBalancedTransportRhea 29283

L-aspartate(in) + 2 H(+)(in) = L-aspartate(out) + 2 H(+)(out)

Direction not assertedBalancedTransportRhea 29287

(25S)-3-oxocholest-4-en-26-oate + ATP + CoA = (25S)-3-oxocholest-4-en-26-oyl-CoA + AMP + diphosphate

Direction not assertedBalancedRhea 29291

aldehydo-D-galacturonate(out) + H(+)(out) = aldehydo-D-galacturonate(in) + H(+)(in)

Direction not assertedBalancedTransportRhea 29295

succinate(in) + 2 H(+)(in) = succinate(out) + 2 H(+)(out)

Left to rightBalancedTransportRhea 29303

methanesulfonate + FMNH2 + O2 = FMN + sulfite + formaldehyde + H2O + 2 H(+)

Direction not assertedBalancedRhea 29307

sulfoacetate + FMNH2 + O2 = FMN + sulfite + glyoxylate + H2O + 2 H(+)

Direction not assertedBalancedRhea 29311

alpha-D-galactose 1-phosphate + H2O = D-galactose + phosphate

Left to rightBalancedRhea 29315

sn-glycero-3-phosphoethanolamine + H2O = ethanolamine + sn-glycerol 3-phosphate + H(+)

Direction not assertedBalancedRhea 29319

fumarate(in) + succinate(out) = fumarate(out) + succinate(in)

Direction not assertedBalancedTransportRhea 29323

(S)-malate(in) + succinate(out) = (S)-malate(out) + succinate(in)

Direction not assertedBalancedTransportRhea 29327

fumarate(in) + 2 H(+)(in) = fumarate(out) + 2 H(+)(out)

Direction not assertedBalancedTransportRhea 29331

L-alanyl-L-glutamate + H2O = L-alanine + L-glutamate

Direction not assertedBalancedRhea 29335

(S)-malate(in) + 2 H(+)(in) = (S)-malate(out) + 2 H(+)(out)

Direction not assertedBalancedTransportRhea 29339

L-aspartate(in) + succinate(out) = L-aspartate(out) + succinate(in)

Direction not assertedBalancedTransportRhea 29343

orotate(in) + 2 H(+)(in) = orotate(out) + 2 H(+)(out)

Direction not assertedBalancedTransportRhea 29347

Zn(2+)(in) = Zn(2+)(out)

ReversibleBalancedTransportRhea 29351

dUMP + H2O = 2'-deoxyuridine + phosphate

Direction not assertedBalancedRhea 29355

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