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Reference

Evidence

CompoundsSubstances with curated findings
OutcomesMeasured endpoints
ProteinsTransporters and enzymes
InteractionsPairs that share biology
PapersEvery paper a finding cites
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Chemistry

ReactionsRhea and Human-GEM, by subsystem
ReachWhat a compound can become

Reference layer

PathwaysReactions grouped under one name
ProcessesWhat proteins are annotated as doing
AnatomyTissues, by what is expressed there
Cell typesCells, by what is expressed there
OrganismsSpecies a compound is prepared from
MaterialsSubstances that are not one molecule
AssessmentsRegulatory determinations, transcribed
DiseasesFeatures, genes, and where each sits

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Reference

Evidence

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Outcomes
Proteins
Interactions
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Chemistry

Reactions
Reach

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Cell types
Organisms
Materials
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Diseases

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Computational infrastructure for human biology, built on a provenance-aware knowledge graph. Findings retain their sources; research and simulation are the next layers.

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A reference for what the literature reports. Not medical advice.

© 2026 CatalystPrivacy TermsReference data under the licences listed on the attribution page.

Index

Reactions

Reactions from Rhea and Human-GEM · Reach

reactions in the graph: 31,435

By source

Rhea18,558
Human-GEM12,877

Inferred

Reference data, not a finding. Evidence key

Filter reactions by equationSource

Reactions

17,101–17,150 of 31,435, by identifier

XMP + H2O = xanthosine + phosphate
Left to rightBalancedRhea 28530
dTTP + H2O = dTMP + diphosphate + H(+)
Direction not assertedBalancedRhea 28534
L-alpha-D-Hep-(1->5)-[alpha-Kdo-(2->4)]-alpha-Kdo-(2->6)-lipid A (E. coli) + ADP-L-glycero-beta-D-manno-heptose = L-alpha-D-Hep-(1->3)-L-alpha-D-Hep-(1->5)-[alpha-Kdo-(2->4)]-alpha-Kdo-(2->6)-lipid A (E. coli) + ADP + H(+)
Direction not assertedBalancedRhea 28538
fluoroacetyl-CoA + H2O = fluoroacetate + CoA + H(+)
Direction not assertedBalancedRhea 28542
alpha-D-glucose = alpha-D-fructose
Direction not assertedBalancedRhea 28546
anthranilate + acetyl-CoA = N-acetylanthranilate + CoA
Direction not assertedBalancedRhea 28550
D-mannose 6-phosphate + H2O = D-mannose + phosphate

Direction not assertedBalancedRhea 28554

D-fructose 6-phosphate + H2O = D-fructose + phosphate

Direction not assertedBalancedRhea 28558

pyridoxal 5'-phosphate + D-alanine = pyridoxamine 5'-phosphate + pyruvate

Direction not assertedBalancedRhea 28562

3 2,3-dihydroxybenzoyl-5'-AMP + 3 L-seryl-5'-AMP = enterobactin + 6 AMP + 7 H(+)

Direction not assertedBalancedRhea 28566

L-serine + ATP = L-seryl-5'-AMP + diphosphate

Direction not assertedBalancedRhea 28570

sulfate(in) + H(+)(in) = sulfate(out) + H(+)(out)

Direction not assertedBalancedTransportRhea 28574

Co(2+)(in) = Co(2+)(out)

Direction not assertedBalancedTransportRhea 28578

dUDP + ATP = dUTP + ADP

Direction not assertedBalancedRhea 28582

N-acetyl-L-lysine + H2O = L-lysine + acetate

Direction not assertedBalancedRhea 28598

L-isoleucine + 2 reduced [NADPH--hemoprotein reductase] + 2 O2 = (1E,2S)-2-methylbutanal oxime + 2 oxidized [NADPH--hemoprotein reductase] + CO2 + 3 H2O + 2 H(+)

Direction not assertedBalance undeterminableRhea 28602

L-valine + 2 reduced [NADPH--hemoprotein reductase] + 2 O2 = (E)-2-methylpropanal oxime + 2 oxidized [NADPH--hemoprotein reductase] + CO2 + 3 H2O + 2 H(+)

Direction not assertedBalance undeterminableRhea 28606

XTP + H2O = XMP + diphosphate + H(+)

Left to rightBalancedRhea 28610

(1Z,2S)-2-methylbutanal oxime = (2S)-2-methylbutanenitrile + H2O

Direction not assertedBalancedRhea 28614

2-methylbutyronitrile + NADPH + O2 + H(+) = 2-hydroxy-2-methylbutanenitrile + NADP(+) + H2O

Direction not assertedBalancedRhea 28618

(-)-vetispiradiene + reduced [NADPH--hemoprotein reductase] + O2 = solavetivol + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Direction not assertedBalance undeterminableRhea 28623

solavetivol + reduced [NADPH--hemoprotein reductase] + O2 = solavetivone + oxidized [NADPH--hemoprotein reductase] + 2 H2O + H(+)

Direction not assertedBalance undeterminableRhea 28627

(2E,6E)-farnesyl diphosphate = (+)-5-epi-aristolochene + diphosphate

Direction not assertedBalancedRhea 28635

(2Z,6E)-farnesyl diphosphate = (-)-gamma-cadinene + diphosphate

Direction not assertedBalancedRhea 28639

(2E,6E)-farnesyl diphosphate = alpha-zingiberene + diphosphate

Direction not assertedBalancedRhea 28643

acetophenone + hydrogencarbonate + 2 ATP + H2O = 3-oxo-3-phenylpropanoate + 2 ADP + 2 phosphate + 2 H(+)

Direction not assertedBalancedRhea 28647

inosine + O2 = 9-riburonosylhypoxanthine + H2O + H(+)

Direction not assertedBalancedRhea 28651

glutathione S,S-dioxide + H2O = sulfite + glutathione + H(+)

Direction not assertedBalancedRhea 28655

beta-lactose + H2O = beta-D-galactose + beta-D-glucose

Direction not assertedBalancedRhea 28659

melibiose + H2O = D-galactose + D-glucose

Direction not assertedBalancedRhea 28663

hydroxyacetone + NADH + H(+) = (S)-propane-1,2-diol + NAD(+)

Direction not assertedBalancedRhea 28667

2 cob(II)alamin + reduced [electron-transfer flavoprotein] + 2 ATP = 2 adenosylcob(III)alamin + 2 triphosphate + oxidized [electron-transfer flavoprotein] + 3 H(+)

Direction not assertedBalance undeterminableRhea 28671

alpha-D-galactose = beta-D-galactose

Right to leftBalancedRhea 28675

3-demethylubiquinol-8 + S-adenosyl-L-methionine = ubiquinol-8 + S-adenosyl-L-homocysteine + H(+)

Direction not assertedBalancedRhea 28679

ubiquinone-8 + L-aspartate = iminosuccinate + ubiquinol-8

Direction not assertedBalancedRhea 28683

(S)-dihydroorotate + ubiquinone-8 = ubiquinol-8 + orotate

Direction not assertedBalancedRhea 28687

(S)-dihydroorotate + a ubiquinone = orotate + a ubiquinol

Direction not assertedBalance undeterminableRhea 28691

hydrogencarbonate(in) = hydrogencarbonate(out)

Right to leftBalancedTransportRhea 28695

Mn(2+)(in) = Mn(2+)(out)

Direction not assertedBalancedTransportRhea 28699

Cu(2+)(in) = Cu(2+)(out)

Right to leftBalancedTransportRhea 28703

Cd(2+)(in) = Cd(2+)(out)

Direction not assertedBalancedTransportRhea 28707

N-(4-aminobenzoyl)-L-glutamate(in) + H(+)(in) = N-(4-aminobenzoyl)-L-glutamate(out) + H(+)(out)

Direction not assertedBalancedTransportRhea 28711

(R)-malate(in) + 2 H(+)(in) = (R)-malate(out) + 2 H(+)(out)

Direction not assertedBalancedTransportRhea 28715

adenine(in) + H(+)(in) = adenine(out) + H(+)(out)

Direction not assertedBalancedTransportRhea 28719

(S)-allantoin(in) + H(+)(in) = (S)-allantoin(out) + H(+)(out)

Direction not assertedBalancedTransportRhea 28723

Cu(2+)(in) + H(+)(in) = Cu(2+)(out) + H(+)(out)

Direction not assertedBalancedTransportRhea 28727

L-leucine(in) + H(+)(out) = L-leucine(out) + H(+)(in)

Direction not assertedBalancedTransportRhea 28731

spermidine(out) + H(+)(in) = spermidine(in) + H(+)(out)

Direction not assertedBalancedTransportRhea 28735

Cd(2+)(in) + H(+)(out) = Cd(2+)(out) + H(+)(in)

Direction not assertedBalancedTransportRhea 28739

nitrate(in) + nitrite(out) = nitrate(out) + nitrite(in)

Direction not assertedBalancedTransportRhea 28743

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