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1,651–1,700 of 12,877 reactions from Human-GEM
3alpha,7alpha-dihydroxy-5beta-cholestan-26-al[c] + H2O[c] + NAD+[c] = 3alpha,7alpha-dihydroxy-5beta-cholestanate[c] + 2 H+[c] + NADH[c]
ReversibleBalancedEC 1.2.1.3Bile acid biosynthesisHuman-GEM MAR01692
3alpha,7alpha-dihydroxy-5beta-cholestan-26-al[m] + NADPH[m] + O2[m] = 3alpha,7alpha-dihydroxy-5beta-cholestanate[m] + H2O[m] + NADP+[m]
Left to rightBalancedEC 1.14.15.15Bile acid biosynthesisHuman-GEM MAR01693
3alpha,7alpha-dihydroxy-5beta-cholestanate[c] = 3alpha,7alpha-dihydroxy-5beta-cholestanate[m]
ReversibleBalancedTransportEC 2.3.1.176, 2.3.1.16Transport reactionsHuman-GEM MAR01694
3alpha,7alpha-dihydroxy-5beta-cholestanate[c] = 3alpha,7alpha-dihydroxy-5beta-cholestanate[r]
Reversible
3alpha,7alpha-dihydroxy-5beta-cholestanate[c] + ATP[c] + H2O[c] = 3alpha,7alpha-dihydroxy-5beta-cholestanate[x] + ADP[c] + H+[c] + Pi[c]
Left to rightBalancedTransportTransport reactionsHuman-GEM MAR01696
3alpha,7alpha-dihydroxy-5beta-cholestanate[c] + ATP[c] + CoA[c] = 25(R)DHCA-CoA[c] + AMP[c] + PPi[c]
Left to rightBalancedEC 6.2.1.28, 6.2.1.7Bile acid biosynthesisHuman-GEM MAR01697
retinyl-ester[c] = retinyl-ester[e]
Left to rightBalance undeterminableTransportTransport reactionsHuman-GEM MAR01698
3alpha,7alpha-dihydroxy-5beta-cholestanate[r] + ATP[r] + CoA[r] = 25(R)DHCA-CoA[r] + AMP[r] + PPi[r]
Left to rightBalancedEC 6.2.1.28, 6.2.1.7Bile acid biosynthesisHuman-GEM MAR01699
3alpha,7alpha-dihydroxy-5beta-cholestanate[x] + ATP[x] + CoA[x] = 25(R)DHCA-CoA[x] + AMP[x] + PPi[x]
Left to rightBalancedEC 6.2.1.28, 6.2.1.7Bile acid biosynthesisHuman-GEM MAR01700
25(R)DHCA-CoA[c] = 25(R)DHCA-CoA[x]
ReversibleBalancedTransportTransport reactionsHuman-GEM MAR01701
25(R)DHCA-CoA[r] + 2 ATP[r] + 2 H2O[r] = 25(R)DHCA-CoA[x] + 2 ADP[r] + 2 H+[r] + 2 Pi[r]
Left to rightBalancedTransportTransport reactionsHuman-GEM MAR01702
25(R)DHCA-CoA[x] = 25(S)DHCA-CoA[x]
ReversibleBalancedEC 5.1.99.4Bile acid biosynthesisHuman-GEM MAR01703
25(S)DHCA-CoA[x] + FAD[x] = 3alpha,7alpha-dihydroxy-5beta-cholest-24-enoyl-CoA[x] + FADH2[x]
Left to rightBalancedEC 1.17.99.3Bile acid biosynthesisHuman-GEM MAR01704
fatty acid 9-cis-retinol[c] = fatty acid 9-cis-retinol[e]
Left to rightBalance undeterminableTransportTransport reactionsHuman-GEM MAR01705
3alpha,7alpha-dihydroxy-5beta-cholest-24-enoyl-CoA[x] + H2O[x] = (24R,25R)3alpha,7alpha,24-trihydroxy-5beta-cholestanoyl-CoA[x]
Left to rightBalancedEC 4.2.1.107Bile acid biosynthesisHuman-GEM MAR01706
H+[e] + ribose[e] = H+[c] + ribose[c]
Left to rightBalancedTransportTransport reactionsHuman-GEM MAR01707
(24R,25R)3alpha,7alpha,24-trihydroxy-5beta-cholestanoyl-CoA[x] + NAD+[x] = 3alpha,7alpha-dihydroxy-24-oxo-5beta-cholestanoyl coa[x] + H+[x] + NADH[x]
Left to rightBalancedEC 4.2.1.107Bile acid biosynthesisHuman-GEM MAR01708
3alpha,7alpha-dihydroxy-24-oxo-5beta-cholestanoyl coa[x] + CoA[x] = chenodeoxycholoyl-CoA[x] + propanoyl-CoA[x]
Left to rightBalancedEC 2.3.1.176Bile acid biosynthesisHuman-GEM MAR01710
7 3alpha,7alpha-dihydroxy-5beta-cholest-24-enoyl-CoA[x] + 3 CO2[x] + 8 CoA[x] + 2 H2O[x] = 8 propanoyl-CoA[x] + 7 chenodeoxyglycocholoyl-CoA[x]
Left to rightBalancedEC 2.7.7.4Bile acid biosynthesisHuman-GEM MAR01711
Protein-Linked Serine Or Threonine Residue (O-Glycosylation Site)[g] = Protein-Linked Serine Or Threonine Residue (O-Glycosylation Site)[l]
ReversibleBalance undeterminableTransportTransport reactionsHuman-GEM MAR01712
de-Fuc, GlcNAc removed PA6 (wo peptide linkage)[c] + 2 H2O[c] = l2n2m2mn[c] + 2 N-acetylneuraminate[c]
Left to rightBalancedEC 3.2.1.18N-glycan metabolismHuman-GEM MAR01713
H+[r] + NADPH[r] + O2[r] + squalene[r] = H2O[r] + NADP+[r] + squalene 2,3-oxide[r]
Left to rightBalancedEC 1.14.14.17Cholesterol metabolismHuman-GEM MAR01714
2 farnesyl-PP[r] + H+[r] + NADPH[r] = NADP+[r] + 2 PPi[r] + squalene[r]
Left to rightBalancedEC 2.5.1.21Cholesterol metabolismHuman-GEM MAR01715
chenodeoxycholoyl-CoA[x] + H2O[x] = chenodiol[x] + CoA[x] + H+[x]
Left to rightBalancedEC 3.1.2.2Bile acid biosynthesisHuman-GEM MAR01716
chenodeoxycholoyl-CoA[c] = chenodeoxycholoyl-CoA[x]
ReversibleBalancedTransportTransport reactionsHuman-GEM MAR01717
chenodeoxycholoyl-CoA[c] + H2O[c] = chenodiol[c] + CoA[c] + H+[c]
Left to rightBalancedEC 3.1.2.2Bile acid biosynthesisHuman-GEM MAR01718
stearoyl-CoA[c] = stearoyl-CoA[x]
ReversibleBalancedTransportEC 2.4.3.7Transport reactionsHuman-GEM MAR01719
chenodeoxycholoyl-CoA[x] + taurine[x] = CoA[x] + taurochenodeoxycholate[x]
Left to rightBalancedEC 2.3.1.65Bile acid biosynthesisHuman-GEM MAR01720
(6Z,9Z,12Z,15Z)-octadecatetraenoylcarnitine[c] = (6Z,9Z,12Z,15Z)-octadecatetraenoylcarnitine[m]
ReversibleBalancedTransportEC 2.4.3.7Fatty acid oxidationHuman-GEM MAR01721
chenodeoxycholoyl-CoA[c] + glycine[c] = CoA[c] + glycochenodeoxycholate[c]
Left to rightBalancedEC 2.3.1.65Bile acid biosynthesisHuman-GEM MAR01722
chenodeoxycholoyl-CoA[c] + taurine[c] = CoA[c] + taurochenodeoxycholate[c]
Left to rightBalancedEC 2.3.1.65Bile acid biosynthesisHuman-GEM MAR01723
4-hydroxyphenyllactate[m] = 4-coumarate[m] + H2O[m]
Left to rightBalancedUbiquinone synthesisHuman-GEM MAR01724
chenodeoxycholoyl-CoA[c] = chenodeoxycholoyl-CoA[r]
ReversibleBalancedTransportTransport reactionsHuman-GEM MAR01725
ATP[c] + chenodiol[c] + CoA[c] = AMP[c] + chenodeoxycholoyl-CoA[c] + PPi[c]
Left to rightBalancedEC 6.2.1.7Bile acid biosynthesisHuman-GEM MAR01726
ATP[r] + chenodiol[r] + CoA[r] = AMP[r] + chenodeoxycholoyl-CoA[r] + PPi[r]
Left to rightBalancedEC 6.2.1.7Bile acid biosynthesisHuman-GEM MAR01727
TAG-VLDL pool[e] = TAG-VLDL pool[c]
ReversibleBalance undeterminableTransportEC 3.1.6.2Transport reactionsHuman-GEM MAR01728
chenodiol[c] + PAPS[c] = H+[c] + PAP[c] + sulfochenodeoxycholate[c]
Left to rightBalancedEC 2.8.2.14Bile acid biosynthesisHuman-GEM MAR01729
H2O[c] + sulfochenodeoxycholate[c] = chenodiol[c] + H+[c] + sulfate[c]
Left to rightBalancedEC 3.1.6.2Bile acid biosynthesisHuman-GEM MAR01730
taurocholate[e] = taurocholate[c]
ReversibleBalancedTransportEC 6.2.1.5Transport reactionsHuman-GEM MAR01731
taurocholate[x] = taurocholate[c]
ReversibleBalancedTransportEC 3.2.1.26Transport reactionsHuman-GEM MAR01732
taurochenodeoxycholate[e] = taurochenodeoxycholate[c]
ReversibleBalancedTransportEC 4.2.1.17Transport reactionsHuman-GEM MAR01733
taurochenodeoxycholate[x] = taurochenodeoxycholate[c]
ReversibleBalancedTransportTransport reactionsHuman-GEM MAR01734
cholesterol[c] + H+[c] + NADPH[c] + O2[c] = 24-hydroxycholesterol[c] + H2O[c] + NADP+[c]
Left to rightBalancedEC 1.14.14.25Bile acid biosynthesisHuman-GEM MAR01735
(9Z,12Z,15Z,18Z,21Z)-tetracosapentaenoylcarnitine[m] + CoA[m] = (9Z,12Z,15Z,18Z,21Z)-tetracosapentaenoyl-CoA[m] + L-carnitine[m]
ReversibleBalancedEC 2.3.1.21Fatty acid oxidationHuman-GEM MAR01736
24-hydroxycholesterol[c] + H+[c] + NADPH[c] + O2[c] = cholest-5-ene-3beta,7alpha,24(S)-triol[c] + H2O[c] + NADP+[c]
Left to rightBalancedEC 1.14.14.26Bile acid biosynthesisHuman-GEM MAR01737
cholest-5-ene-3beta,7alpha,24(S)-triol[c] + NAD+[c] = 4-cholesten-7alpha,24(S)-diol-3-one[c] + H+[c] + NADH[c]
Left to rightBalancedEC 1.1.1.181Bile acid biosynthesisHuman-GEM MAR01738
4-cholesten-7alpha,24(S)-diol-3-one[c] + H+[c] + NADPH[c] + O2[c] = 4-cholesten-7alpha,12alpha,24(S)-triol-3-one[c] + H2O[c] + NADP+[c]
Left to rightBalancedEC 1.14.14.139Bile acid biosynthesisHuman-GEM MAR01739
4-cholesten-7alpha,12alpha,24(S)-triol-3-one[c] + H+[c] + NADPH[c] = 5beta-cholestan-7alpha,12alpha,24(S)-triol-3-one[c] + NADP+[c]
Left to rightBalancedEC 1.3.1.3Bile acid biosynthesisHuman-GEM MAR01740
4-cholesten-7alpha,24(S)-diol-3-one[c] + H+[c] + NADPH[c] = 5beta-cholestan-7alpha,24(S)-diol-3-one[c] + NADP+[c]
Left to rightBalancedEC 1.3.1.3Bile acid biosynthesisHuman-GEM MAR01741
5beta-cholestan-7alpha,12alpha,24(S)-triol-3-one[c] + H+[c] + NADPH[c] = 5beta-cholestan-3alpha,7alpha,12alpha,24(S)-tetrol[c] + NADP+[c]
Left to rightBalancedEC 1.1.1.50Bile acid biosynthesisHuman-GEM MAR01742