Skip to content

Reference

Evidence

CompoundsSubstances with curated findings
OutcomesMeasured endpoints
ProteinsTransporters and enzymes
InteractionsPairs that share biology
PapersEvery paper a finding cites
ArticlesReadings of the evidence

Chemistry

ReactionsRhea and Human-GEM, by subsystem
ReachWhat a compound can become

Reference layer

PathwaysReactions grouped under one name
ProcessesWhat proteins are annotated as doing
AnatomyTissues, by what is expressed there
Cell typesCells, by what is expressed there
OrganismsSpecies a compound is prepared from
MaterialsSubstances that are not one molecule
AssessmentsRegulatory determinations, transcribed
DiseasesFeatures, genes, and where each sits

Atlas Graph Twin Access

Search the graph

Reference

Evidence

Compounds
Outcomes
Proteins
Interactions
Papers
Articles

Chemistry

Reactions
Reach

Reference layer

Pathways
Processes
Anatomy
Cell types
Organisms
Materials
Assessments
Diseases

Atlas Graph Twin Access

Loading the page.

Catalyst

Computational infrastructure for human biology, built on a provenance-aware knowledge graph. Findings retain their sources; research and simulation are the next layers.

The graph

Compounds
Outcomes
Proteins
Atlas
Interactions
Papers
Articles
Graph
Search

Reference layer

Pathways
Processes
Anatomy
Cell types
Organisms
Materials
Assessments
Diseases
Reactions
Reach

How it works

Mission
Method
Twin
How to read the evidence
Sources and licences

Build on it

Access
In your assistant
For agents
Query the graph
Bulk export

A reference for what the literature reports. Not medical advice.

© 2026 CatalystPrivacy TermsReference data under the licences listed on the attribution page.

Index

Reactions

Reactions from Rhea and Human-GEM · Reach

reactions in the graph: 31,435

By source

Rhea18,558
Human-GEM12,877

Inferred

Reference data, not a finding. Evidence key

Filter reactions by equationSource

Reactions

16,801–16,850 of 31,435, by identifier

2-formylbenzoate + NAD(+) + H2O = phthalate + NADH + 2 H(+)
Direction not assertedBalancedRhea 27298
7-chloro-L-tryptophan + O2 = 3-(7-chloroindol-3-yl)-2-iminopropanoate + H2O2
Direction not assertedBalancedRhea 27302
D-proline + A = 1-pyrroline-2-carboxylate + AH2
Direction not assertedBalancedRhea 27306
naphthalene-1,2-diol + O2 = 2-hydroxychromene-2-carboxylate + H(+)
Direction not assertedBalancedRhea 27310
dichlorochromopyrrolate + 4 NADH + 4 O2 + 6 H(+) = dichloroarcyriaflavin A + 2 CO2 + 4 NAD(+) + 6 H2O
Direction not assertedBalancedRhea 27314
3-epi-6-deoxocathasterone + reduced [NADPH--hemoprotein reductase] + O2 = 6-deoxotyphasterol + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)
Direction not assertedBalance undeterminableRhea 27321
(22S,24R)-22-hydroxy-5alpha-ergostan-3-one + reduced [NADPH--hemoprotein reductase] + O2 = 3-dehydro-6-deoxoteasterone + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Direction not assertedBalance undeterminableRhea 27325

urate + NADH + O2 + H(+) = 5-hydroxyisourate + NAD(+) + H2O

Direction not assertedBalancedRhea 27329

6-hydroxynicotinate + NADH + O2 + 2 H(+) = 2,5-dihydroxypyridine + CO2 + NAD(+) + H2O

Direction not assertedBalancedRhea 27333

reduced 2[4Fe-4S]-[ferredoxin] + progesterone + O2 + 2 H(+) = 15beta-hydroxyprogesterone + oxidized 2[4Fe-4S]-[ferredoxin] + H2O

Direction not assertedBalance undeterminableRhea 27337

AH2 + NH4(+) + O2 = hydroxylamine + A + H2O + H(+)

Direction not assertedBalancedRhea 27341

FMNH2 + O2 = dialurate + 5,6-dimethylbenzimidazole + D-erythrose 4-phosphate + H(+)

Direction not assertedBalancedRhea 27345

mycothiol + arsenate = arseno-mycothiol + H2O

Direction not assertedBalancedRhea 27349

4'-demethylrebeccamycin + S-adenosyl-L-methionine = rebeccamycin + S-adenosyl-L-homocysteine + H(+)

Direction not assertedBalancedRhea 27353

iodide + S-adenosyl-L-methionine = iodomethane + S-adenosyl-L-homocysteine

Direction not assertedBalancedRhea 27357

chloride + S-adenosyl-L-methionine = chloromethane + S-adenosyl-L-homocysteine

Direction not assertedBalancedRhea 27361

bromide + S-adenosyl-L-methionine = bromomethane + S-adenosyl-L-homocysteine

Direction not assertedBalancedRhea 27365

acetoin + NAD(+) + CoA = acetaldehyde + acetyl-CoA + NADH + H(+)

Direction not assertedBalancedRhea 27369

(R)-glycerate + ATP = (2R)-2-phosphoglycerate + ADP + H(+)

Direction not assertedBalancedRhea 27377

(2R)-2,3-bisphosphoglycerate + H2O = (2R)-2-phosphoglycerate + phosphate

Left to rightBalancedRhea 27381

maleamate + H2O = maleate + NH4(+)

Direction not assertedBalancedRhea 27385

(3E)-4-(2-hydroxyphenyl)-2-oxobut-3-enoate + H2O = salicylaldehyde + pyruvate

Direction not assertedBalancedRhea 27389

2 3-(7-chloroindol-3-yl)-2-iminopropanoate + H2O2 = dichlorochromopyrrolate + NH4(+) + 2 H2O + H(+)

Direction not assertedBalancedRhea 27393

4'-demethylrebeccamycin + H2O = dichloroarcyriaflavin A + beta-D-glucose

Direction not assertedBalancedRhea 27397

2-hydroxychromene-2-carboxylate = (3E)-4-(2-hydroxyphenyl)-2-oxobut-3-enoate

Direction not assertedBalancedRhea 27401

a ubiquinone + pyruvate + H2O = a ubiquinol + acetate + CO2

Direction not assertedBalance undeterminableRhea 27405

protoporphyrinogen IX + 3 a menaquinone = protoporphyrin IX + 3 a menaquinol

Direction not assertedBalance undeterminableRhea 27409

codeine + 2-oxoglutarate + O2 = morphine + formaldehyde + succinate + CO2

Direction not assertedBalancedRhea 27413

2 Fe(III)-[cytochrome] + nicotinate + H2O = 2 Fe(II)-[cytochrome] + 6-hydroxynicotinate + 2 H(+)

Direction not assertedBalance undeterminableRhea 27417

(2E,6E)-farnesyl diphosphate = (3E,6E)-alpha-farnesene + diphosphate

Direction not assertedBalancedRhea 27421

(2E,6E)-farnesyl diphosphate = (E)-beta-farnesene + diphosphate

Direction not assertedBalancedRhea 27425

a 1,2-diacyl-sn-glycero-3-phosphate + H2O = a 1,2-diacyl-sn-glycerol + phosphate

Left to rightBalance undeterminableRhea 27429

2 glutathione amide + NAD(+) = glutathione amide disulfide + NADH + H(+)

Direction not assertedBalancedRhea 27433

2 glutathione amide + H2O2 = glutathione amide disulfide + 2 H2O

Direction not assertedBalancedRhea 27437

xylitol + NAD(+) = D-xylose + NADH + H(+)

Direction not assertedBalancedRhea 27441

xylitol + NADP(+) = D-xylose + NADPH + H(+)

Direction not assertedBalancedRhea 27445

a 1,2-diacyl-sn-glycerol 3-diphosphate + H2O = a 1,2-diacyl-sn-glycero-3-phosphate + phosphate + H(+)

Left to rightBalance undeterminableRhea 27449

iodide + L-tyrosine + NADP(+) = 3-iodo-L-tyrosine + NADPH

Right to leftBalancedRhea 27453

3-iodo-L-tyrosine + iodide + NADP(+) = 3,5-diiodo-L-tyrosine + NADPH + H(+)

Right to leftBalancedRhea 27457

D-glycero-alpha-D-manno-heptose 1-phosphate + GTP + H(+) = GDP-D-glycero-alpha-D-manno-heptose + diphosphate

Direction not assertedBalancedRhea 27461

D-glycero-beta-D-manno-heptose 1-phosphate + ATP + H(+) = ADP-D-glycero-beta-D-manno-heptose + diphosphate

Direction not assertedBalancedRhea 27465

N,N'-diacetylchitobiose + H2O = N-acetyl-beta-D-glucosaminyl-(1->4)-D-glucosamine + acetate

Direction not assertedBalancedRhea 27469

D-glycero-beta-D-manno-heptose 7-phosphate + ATP = D-glycero-beta-D-manno-heptose 1,7-bisphosphate + ADP + H(+)

Direction not assertedBalancedRhea 27473

thebaine + 2-oxoglutarate + O2 = neopinone + formaldehyde + succinate + CO2

Direction not assertedBalancedRhea 27477

(S)-columbianetin + reduced [NADPH--hemoprotein reductase] + O2 = angelicin + acetone + oxidized [NADPH--hemoprotein reductase] + 2 H2O + H(+)

Direction not assertedBalance undeterminableRhea 27481

allantoate + H2O + 2 H(+) = (S)-2-ureidoglycine + NH4(+) + CO2

Direction not assertedBalancedRhea 27485

2 D-sedoheptulose 7-phosphate = D-glycero-alpha-D-manno-heptose 7-phosphate + D-glycero-beta-D-manno-heptose 7-phosphate

Direction not assertedBalancedRhea 27489

tricetin + S-adenosyl-L-methionine = 3'-O-methyltricetin + S-adenosyl-L-homocysteine + H(+)

Direction not assertedBalancedRhea 27493

3'-O-methyltricetin + S-adenosyl-L-methionine = 3',5'-di-O-methyltricetin + S-adenosyl-L-homocysteine + H(+)

Direction not assertedBalancedRhea 27497

3',5'-di-O-methyltricetin + S-adenosyl-L-methionine = 3',4',5'-O-trimethyltricetin + S-adenosyl-L-homocysteine + H(+)

Direction not assertedBalancedRhea 27501

Page 337 of 629