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Reference

Evidence

CompoundsSubstances with curated findings
OutcomesMeasured endpoints
ProteinsTransporters and enzymes
InteractionsPairs that share biology
PapersEvery paper a finding cites
ArticlesReadings of the evidence

Chemistry

ReactionsRhea and Human-GEM, by subsystem
ReachWhat a compound can become

Reference layer

PathwaysReactions grouped under one name
ProcessesWhat proteins are annotated as doing
AnatomyTissues, by what is expressed there
Cell typesCells, by what is expressed there
OrganismsSpecies a compound is prepared from
MaterialsSubstances that are not one molecule
AssessmentsRegulatory determinations, transcribed
DiseasesFeatures, genes, and where each sits

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Reference

Evidence

Compounds
Outcomes
Proteins
Interactions
Papers
Articles

Chemistry

Reactions
Reach

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Anatomy
Cell types
Organisms
Materials
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Diseases

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Computational infrastructure for human biology, built on a provenance-aware knowledge graph. Findings retain their sources; research and simulation are the next layers.

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A reference for what the literature reports. Not medical advice.

© 2026 CatalystPrivacy TermsReference data under the licences listed on the attribution page.

Index

Reactions

Reactions from Rhea and Human-GEM · Reach

reactions in the graph: 31,435

By source

Rhea18,558
Human-GEM12,877

Inferred

Reference data, not a finding. Evidence key

Filter reactions by equationSource

Reactions

16,501–16,550 of 31,435, by identifier

7,8-dihydroneopterin + phosphate = 7,8-dihydroneopterin 3'-phosphate + H2O
Direction not assertedBalancedRhea 25306
glycolate + O2 = glyoxylate + H2O2
Left to rightBalancedRhea 25311
N-acetyl-(2S,6S)-2,6-diaminopimelate + 2-oxoglutarate = L-2-acetamido-6-oxoheptanedioate + L-glutamate
Direction not assertedBalancedRhea 25315
N-methylethanolamine phosphate + S-adenosyl-L-methionine = N,N-dimethylethanolamine phosphate + S-adenosyl-L-homocysteine + H(+)
Direction not assertedBalancedRhea 25321
N,N-dimethylethanolamine phosphate + S-adenosyl-L-methionine = phosphocholine + S-adenosyl-L-homocysteine + H(+)
Direction not assertedBalancedRhea 25325
(R)-carnitine + NAD(+) = 3-dehydrocarnitine + NADH + H(+)
Direction not assertedBalancedRhea 25330
L-cysteinyl-tRNA(Cys) + H2O = tRNA(Cys) + L-cysteine + H(+)

Direction not assertedBalancedRhea 25334

urea + H(+) = isocyanate + NH4(+)

Direction not assertedBalancedRhea 25338

urea + H2O = carbamate + NH4(+)

Direction not assertedBalancedRhea 25342

D-tyrosyl-tRNA(Tyr) + H2O = D-tyrosine + tRNA(Tyr)

Direction not assertedBalancedRhea 25347

L-cysteinyl-tRNA(Pro) + H2O = tRNA(Pro) + L-cysteine + H(+)

Direction not assertedBalancedRhea 25351

2-hydroxyphytanoyl-CoA = 2,6,10,14-tetramethylpentadecanal + formyl-CoA

Left to rightBalancedRhea 25355

(3Z)-phycoerythrobilin + 2 oxidized 2[4Fe-4S]-[ferredoxin] = biliverdin IXalpha + 2 reduced 2[4Fe-4S]-[ferredoxin] + 4 H(+)

Direction not assertedBalance undeterminableRhea 25359

3beta-hydroxy-9beta-pimara-7,15-dien-19,6beta-olide + NAD(+) = momilactone A + NADH + H(+)

Direction not assertedBalancedRhea 25363

3beta-hydroxy-9beta-pimara-7,15-dien-19,6beta-olide + NADP(+) = momilactone A + NADPH + H(+)

Direction not assertedBalancedRhea 25367

(2S)-2-amino-4-deoxychorismate + FMN = 3-(1-carboxyvinyloxy)anthranilate + FMNH2

Direction not assertedBalancedRhea 25371

a 2-hydroxy-3-methyl fatty acyl-CoA = a 2-methyl-branched fatty aldehyde + formyl-CoA

Left to rightBalance undeterminableRhea 25375

2-hydroxy-3-methylhexadecanoyl-CoA = 2-methylpentadecanal + formyl-CoA

Left to rightBalancedRhea 25379

(3Z)-6-oxohex-3-enoyl-CoA + NADP(+) + H2O = cis-3,4-dehydroadipyl-CoA + NADPH + 2 H(+)

Direction not assertedBalancedRhea 25391

(9Z,12Z)-octadecadienoate + O2 = (8R,9Z,12Z)-8-hydroperoxyoctadeca-9,12-dienoate

Direction not assertedBalancedRhea 25395

(8R,9Z,12Z)-8-hydroperoxyoctadeca-9,12-dienoate = (7S,8S,9Z,12Z)-7,8-dihydroxyoctadeca-9,12-dienoate

Direction not assertedBalancedRhea 25399

(S)-2-ethyl-2-hydroxy-3-oxobutanoate = (R)-3-hydroxy-3-methyl-2-oxopentanoate

Direction not assertedBalancedRhea 25404

ADP-alpha-D-glucose + D-glucose = alpha,alpha-trehalose + ADP + H(+)

Direction not assertedBalancedRhea 25408

octadecanoyl-CoA + AH2 + O2 = (9Z)-octadecenoyl-CoA + A + 2 H2O

Direction not assertedBalancedRhea 25416

3-hydroxybenzoyl-CoA + AH2 + 2 ATP + 2 H2O = 3-hydroxycyclohexa-1,5-diene-1-carbonyl-CoA + A + 2 ADP + 2 phosphate + 2 H(+)

Direction not assertedBalancedRhea 25420

GMP + diphosphate = guanine + 5-phospho-alpha-D-ribose 1-diphosphate

Right to leftBalancedRhea 25424

N-acetyl-D-hexosamine + ATP = N-acetyl-alpha-D-hexosamine 1-phosphate + ADP + H(+)

Direction not assertedBalancedRhea 25428

beta-D-ribopyranose = beta-D-ribofuranose

Direction not assertedBalancedRhea 25432

(2E,6E)-farnesyl diphosphate = (E,R)-alpha-bisabolene + diphosphate

Direction not assertedBalancedRhea 25436

(2E,6E)-farnesyl diphosphate = delta-selinene + diphosphate

Direction not assertedBalancedRhea 25440

(2E,6E)-farnesyl diphosphate = (1E,4E)-germacrene B + diphosphate

Direction not assertedBalancedRhea 25444

(2E,6E)-farnesyl diphosphate = (+)-guaia-6,9-diene + diphosphate

Direction not assertedBalancedRhea 25448

(2E,6E)-farnesyl diphosphate = germacrene A + diphosphate

Direction not assertedBalancedRhea 25452

(2E,6E)-farnesyl diphosphate = gamma-humulene + diphosphate

Direction not assertedBalancedRhea 25456

(2E,6E)-farnesyl diphosphate = sibirene + diphosphate

Direction not assertedBalancedRhea 25460

(2E,6E)-farnesyl diphosphate = longifolene + diphosphate

Direction not assertedBalancedRhea 25464

(2E,6E)-farnesyl diphosphate = beta-himachalene + diphosphate

Direction not assertedBalancedRhea 25468

(2E,6E)-farnesyl diphosphate = gamma-himachalene + diphosphate

Direction not assertedBalancedRhea 25472

(2E,6E)-farnesyl diphosphate = alpha-himachalene + diphosphate

Direction not assertedBalancedRhea 25476

acetoacetate + succinyl-CoA = acetoacetyl-CoA + succinate

Left to rightBalancedRhea 25480

(2E)-geranyl diphosphate = (1S,4R)-camphene + diphosphate

Direction not assertedBalancedRhea 25484

(2E)-geranyl diphosphate = (1S,5S)-alpha-pinene + diphosphate

Direction not assertedBalancedRhea 25488

(2E)-geranyl diphosphate = (-)-beta-phellandrene + diphosphate

Direction not assertedBalancedRhea 25492

(2E)-geranyl diphosphate = (1S,5S)-beta-pinene + diphosphate

Direction not assertedBalancedRhea 25496

(2E)-geranyl diphosphate = terpinolene + diphosphate

Direction not assertedBalancedRhea 25500

(2E)-geranyl diphosphate = beta-phellandrene + diphosphate

Direction not assertedBalancedRhea 25504

(2E)-geranyl diphosphate = (1S,5S)-sabinene + diphosphate

Direction not assertedBalancedRhea 25508

(2S)-2-amino-4-deoxychorismate + L-glutamate = chorismate + L-glutamine

Direction not assertedBalancedRhea 25512

tropine + an acyl-CoA = an O-acyltropine + CoA + H(+)

Direction not assertedBalance undeterminableRhea 25516

pseudotropine + an acyl-CoA = an O-acylpseudotropine + CoA + H(+)

Direction not assertedBalance undeterminableRhea 25520

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