Skip to content

Reference

Evidence

CompoundsSubstances with curated findings
OutcomesMeasured endpoints
ProteinsTransporters and enzymes
InteractionsPairs that share biology
PapersEvery paper a finding cites
ArticlesReadings of the evidence

Chemistry

ReactionsRhea and Human-GEM, by subsystem
ReachWhat a compound can become

Reference layer

PathwaysReactions grouped under one name
ProcessesWhat proteins are annotated as doing
AnatomyTissues, by what is expressed there
Cell typesCells, by what is expressed there
OrganismsSpecies a compound is prepared from
MaterialsSubstances that are not one molecule
AssessmentsRegulatory determinations, transcribed
DiseasesFeatures, genes, and where each sits

Atlas Graph Twin Access

Search the graph

Reference

Evidence

Compounds
Outcomes
Proteins
Interactions
Papers
Articles

Chemistry

Reactions
Reach

Reference layer

Pathways
Processes
Anatomy
Cell types
Organisms
Materials
Assessments
Diseases

Atlas Graph Twin Access

Loading the page.

Catalyst

Computational infrastructure for human biology, built on a provenance-aware knowledge graph. Findings retain their sources; research and simulation are the next layers.

The graph

Compounds
Outcomes
Proteins
Atlas
Interactions
Papers
Articles
Graph
Search

Reference layer

Pathways
Processes
Anatomy
Cell types
Organisms
Materials
Assessments
Diseases
Reactions
Reach

How it works

Mission
Method
Twin
How to read the evidence
Sources and licences

Build on it

Access
In your assistant
For agents
Query the graph
Bulk export

A reference for what the literature reports. Not medical advice.

© 2026 CatalystPrivacy TermsReference data under the licences listed on the attribution page.

Index

Reactions

Reactions from Rhea and Human-GEM · Reach

reactions in the graph: 31,435

By source

Rhea18,558
Human-GEM12,877

Inferred

Reference data, not a finding. Evidence key

Filter reactions by equationSource

Reactions

16,201–16,250 of 31,435, by identifier

D-gluconate + NAD(+) = 5-dehydro-D-gluconate + NADH + H(+)
Direction not assertedBalancedRhea 23940
(E)-coniferol + UDP-alpha-D-glucose = 4-O-(beta-D-glucosyl)-(E)-coniferol + UDP + H(+)
Direction not assertedBalancedRhea 23944
4-hydroxybutanoate + NAD(+) = succinate semialdehyde + NADH + H(+)
Direction not assertedBalancedRhea 23948
N-(2-phenylethyl)acetamide + H2O = 2-phenylethylamine + acetate
Direction not assertedBalancedRhea 23952
L-seryl-[protein] + UDP-N-acetyl-alpha-D-galactosamine = a 3-O-[N-acetyl-alpha-D-galactosaminyl]-L-seryl-[protein] + UDP + H(+)
Left to rightBalance undeterminableRhea 23956
hexadecanoate + 2 H2O2 + H(+) = pentadecanal + CO2 + 3 H2O
Direction not assertedBalancedRhea 23960
(E)-coniferaldehyde + NADP(+) + H2O = (E)-ferulate + NADPH + 2 H(+)

Direction not assertedBalancedRhea 23964

(E)-coniferaldehyde + NAD(+) + H2O = (E)-ferulate + NADH + 2 H(+)

Direction not assertedBalancedRhea 23968

(2E)-glutaconyl-CoA + Na(+)(in) + H(+) = (2E)-butenoyl-CoA + Na(+)(out) + CO2

Direction not assertedBalancedTransportRhea 23972

a 3'-end 3'-phospho-ribonucleotide-RNA + ATP = a 3'-end 2',3'-cyclophospho-ribonucleotide-RNA + AMP + diphosphate

Direction not assertedBalance undeterminableRhea 23976

cyclomaltodextrin + H2O = linear maltodextrin

Direction not assertedBalance undeterminableRhea 23980

cholesterol + NADP(+) = 7-dehydrocholesterol + NADPH + H(+)

Right to leftBalancedRhea 23984

(2S,6S)-2,6-diaminopimelate + 2-oxoglutarate = (S)-2,3,4,5-tetrahydrodipicolinate + L-glutamate + H2O + H(+)

Direction not assertedBalancedRhea 23988

a 1-O-alkyl-sn-glycero-3-phosphocholine + an acyl-CoA = a 1-O-alkyl-2-acyl-sn-glycero-3-phosphocholine + CoA

Direction not assertedBalance undeterminableRhea 23992

a ribonucleoside 5'-triphosphate + H2O = a ribonucleoside 5'-phosphate + diphosphate + H(+)

Left to rightBalance undeterminableRhea 23996

a 6-O-methyl-2'-deoxyguanosine in DNA + L-cysteinyl-[protein] = S-methyl-L-cysteinyl-[protein] + a 2'-deoxyguanosine in DNA

Direction not assertedBalance undeterminableRhea 24000

butanoyl-CoA + oxidized [electron-transfer flavoprotein] + H(+) = (2E)-butenoyl-CoA + reduced [electron-transfer flavoprotein]

Left to rightBalance undeterminableRhea 24004

hypotaurocyamine + ATP = N(omega)-phosphohypotaurocyamine + ADP + H(+)

Direction not assertedBalancedRhea 24008

gamma-tocopherol + S-adenosyl-L-methionine = (+)-alpha-tocopherol + S-adenosyl-L-homocysteine + H(+)

Direction not assertedBalancedRhea 24012

16-epivellosimine + acetyl-CoA = vinorine + CoA

Direction not assertedBalancedRhea 24016

2-(N(omega)-L-arginino)succinate = fumarate + L-arginine

ReversibleBalancedRhea 24020

(2E,5S,6E,8E,10E)-1-aminododeca-2,6,8,10-tetraen-5-ol + pyruvate = (2E,5S,6E,8E,10E)-5-hydroxydodeca-2,6,8,10-tetraenal + L-alanine

Direction not assertedBalancedRhea 24024

4-(trimethylamino)butanoate + 2-oxoglutarate + O2 = carnitine + succinate + CO2

Direction not assertedBalancedRhea 24028

sucrose = 6-O-alpha-D-glucopyranosyl-D-fructose

Direction not assertedBalancedRhea 24032

a ribonucleoside 5'-phosphate + ATP = a ribonucleoside 5'-diphosphate + ADP

Direction not assertedBalance undeterminableRhea 24036

2 oxidized [cytochrome P450] + NADPH = 2 reduced [cytochrome P450] + NADP(+) + H(+)

Direction not assertedBalance undeterminableRhea 24040

3,4-dihydroxybenzoate + O2 = 4-carboxy-2-hydroxy-cis,cis-muconate 6-semialdehyde + H(+)

Direction not assertedBalancedRhea 24044

sucrose + phosphate = D-fructose + alpha-D-glucose 1-phosphate

Direction not assertedBalancedRhea 24048

a ubiquinone + reduced [electron-transfer flavoprotein] = a ubiquinol + oxidized [electron-transfer flavoprotein] + H(+)

Left to rightBalance undeterminableRhea 24052

a myo-inositol phosphate + H2O = myo-inositol + phosphate

Left to rightBalancedRhea 24056

N-hydroxy-L-tyrosine + reduced [NADPH--hemoprotein reductase] + O2 = N,N-dihydroxy-L-tyrosine + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Direction not assertedBalance undeterminableRhea 24060

2 5-aminolevulinate = porphobilinogen + 2 H2O + H(+)

Direction not assertedBalancedRhea 24064

cyclohexanone + NADPH + O2 + H(+) = hexano-6-lactone + NADP(+) + H2O

Direction not assertedBalancedRhea 24068

a 3beta-hydroxy-Delta(5)-steroid + NAD(+) = a 3-oxo-Delta(5)-steroid + NADH + H(+)

Direction not assertedBalance undeterminableRhea 24076

tRNA(Trp) + L-tryptophan + ATP = L-tryptophyl-tRNA(Trp) + AMP + diphosphate + H(+)

Left to rightBalancedRhea 24080

all-trans-zeaxanthin + 2 reduced [2Fe-2S]-[ferredoxin] + O2 + 2 H(+) = all-trans-antheraxanthin + 2 oxidized [2Fe-2S]-[ferredoxin] + H2O

Direction not assertedBalance undeterminableRhea 24084

2 sulochrin + O2 + 2 H(+) = 2 (2S)-bisdechlorogeodin + 2 H2O

Direction not assertedBalancedRhea 24092

isoorientin + S-adenosyl-L-methionine = isoscoparin + S-adenosyl-L-homocysteine + H(+)

Direction not assertedBalancedRhea 24096

diisopropyl fluorophosphate + H2O = diisopropyl phosphate + fluoride + 2 H(+)

Direction not assertedBalancedRhea 24100

7-aminomethyl-7-carbaguanine + guanosine(34) in tRNA = 7-aminomethyl-7-carbaguanosine(34) in tRNA + guanine

Direction not assertedBalancedRhea 24104

N-methyl-2-oxoglutaramate + H2O = methylamine + 2-oxoglutarate

Direction not assertedBalancedRhea 24108

2 glutathione + O2 = glutathione disulfide + H2O2

Direction not assertedBalancedRhea 24112

(2E)-geranyl diphosphate + H2O = (S)-linalool + diphosphate

Direction not assertedBalancedRhea 24116

leukotriene E4 + NADPH + O2 + H(+) = 20-hydroxy-leukotriene E4 + NADP(+) + H2O

Direction not assertedBalancedRhea 24120

UDP-alpha-D-galactose = UDP-alpha-D-galactofuranose

Direction not assertedBalancedRhea 24132

a primary amine + 3'-phosphoadenylyl sulfate = a sulfamate + adenosine 3',5'-bisphosphate + 2 H(+)

Direction not assertedBalance undeterminableRhea 24136

guanosine(2251) in 23S rRNA + S-adenosyl-L-methionine = 2'-O-methylguanosine(2251) in 23S rRNA + S-adenosyl-L-homocysteine + H(+)

Direction not assertedBalancedRhea 24140

3-hydroxy-3-(4-methylpent-3-en-1-yl)glutaryl-CoA = 3-(4-methylpent-3-en-1-yl)pent-2-enedioyl-CoA + H2O

Direction not assertedBalancedRhea 24144

D-glyceraldehyde 3-phosphate + 2 oxidized [2Fe-2S]-[ferredoxin] + H2O = (2R)-3-phosphoglycerate + 2 reduced [2Fe-2S]-[ferredoxin] + 3 H(+)

Direction not assertedBalance undeterminableRhea 24148

adenosine 5'-phosphosulfate + ATP = 3'-phosphoadenylyl sulfate + ADP + H(+)

Left to rightBalancedRhea 24152

Page 325 of 629