Skip to content

Reference

Evidence

CompoundsSubstances with curated findings
OutcomesMeasured endpoints
ProteinsTransporters and enzymes
InteractionsPairs that share biology
PapersEvery paper a finding cites
ArticlesReadings of the evidence

Chemistry

ReactionsRhea and Human-GEM, by subsystem
ReachWhat a compound can become

Reference layer

PathwaysReactions grouped under one name
ProcessesWhat proteins are annotated as doing
AnatomyTissues, by what is expressed there
Cell typesCells, by what is expressed there
OrganismsSpecies a compound is prepared from
MaterialsSubstances that are not one molecule
AssessmentsRegulatory determinations, transcribed
DiseasesFeatures, genes, and where each sits

Atlas Graph Twin Access

Search the graph

Reference

Evidence

Compounds
Outcomes
Proteins
Interactions
Papers
Articles

Chemistry

Reactions
Reach

Reference layer

Pathways
Processes
Anatomy
Cell types
Organisms
Materials
Assessments
Diseases

Atlas Graph Twin Access

Loading the page.

Catalyst

Computational infrastructure for human biology, built on a provenance-aware knowledge graph. Findings retain their sources; research and simulation are the next layers.

The graph

Compounds
Outcomes
Proteins
Atlas
Interactions
Papers
Articles
Graph
Search

Reference layer

Pathways
Processes
Anatomy
Cell types
Organisms
Materials
Assessments
Diseases
Reactions
Reach

How it works

Mission
Method
Twin
How to read the evidence
Sources and licences

Build on it

Access
In your assistant
For agents
Query the graph
Bulk export

A reference for what the literature reports. Not medical advice.

© 2026 CatalystPrivacy TermsReference data under the licences listed on the attribution page.

Index

Reactions

Reactions from Rhea and Human-GEM · Reach

reactions in the graph: 31,435

By source

Rhea18,558
Human-GEM12,877

Inferred

Reference data, not a finding. Evidence key

Filter reactions by equationSource

Reactions

15,851–15,900 of 31,435, by identifier

N-formimidoyl-L-glutamate + H2O = formamide + L-glutamate
Direction not assertedBalancedRhea 22492
(E)-feruloyl-CoA + malonyl-CoA + H(+) = (E)-feruloylacetyl-CoA + CO2 + CoA
Direction not assertedBalancedRhea 22500
quercetin 3-sulfate + 3'-phosphoadenylyl sulfate = quercetin 3,3'-bissulfate + adenosine 3',5'-bisphosphate + H(+)
Direction not assertedBalancedRhea 22504
DNA(n) + a 2'-deoxyribonucleoside 5'-triphosphate = DNA(n+1) + diphosphate
Left to rightBalance undeterminableRhea 22508
precorrin-8X + 3 H(+) = hydrogenobyrinate
Direction not assertedBalancedRhea 22512
taurocyamine + ATP = N-phosphotaurocyamine + ADP + H(+)
Direction not assertedBalancedRhea 22516
all-trans-retinal + O2 + H2O = all-trans-retinoate + H2O2 + H(+)

Direction not assertedBalancedRhea 22520

a carotenoid beta-end derivative + 2 A = a carotenoid phi-end derivative + 2 AH2

Direction not assertedBalance undeterminableRhea 22524

a flavonol 3-O-beta-D-glucoside + UDP-beta-L-rhamnose = a flavonol 3-O-[alpha-L-rhamnosyl-(1->6)-beta-D-glucoside] + UDP + H(+)

Direction not assertedBalance undeterminableRhea 22528

(2E)-octenedioyl-CoA + H2O = (3S)-hydroxyoctanedioyl-CoA

Direction not assertedBalancedRhea 22532

(S)-tetrahydrocolumbamine + S-adenosyl-L-methionine = (S)-tetrahydropalmatine + S-adenosyl-L-homocysteine + H(+)

Direction not assertedBalancedRhea 22536

5'-dehydroadenosine + O2 + H2O = 9-riburonosyladenine + H2O2 + H(+)

Direction not assertedBalancedRhea 22540

a 1-O-(1Z-alkenyl)-sn-glycero-3-phosphocholine + H2O = a 2,3-saturated aldehyde + sn-glycerol 3-phosphocholine

Direction not assertedBalance undeterminableRhea 22544

L-lysine + O2 + H2O = (S)-2-amino-6-oxohexanoate + H2O2 + NH4(+)

Direction not assertedBalancedRhea 22548

an alcohol + 3'-phosphoadenylyl sulfate = an alkyl sulfate + adenosine 3',5'-bisphosphate + H(+)

Left to rightBalance undeterminableRhea 22552

(3R)-vestitone + NADP(+) = 2'-hydroxyformononetin + NADPH + 2 H(+)

Direction not assertedBalancedRhea 22560

a 2,3-saturated acyl-[ACP] + NADP(+) = a (2E)-enoyl-[ACP] + NADPH + H(+)

Right to leftBalance undeterminableRhea 22564

ascopyrone M = ascopyrone P

Direction not assertedBalancedRhea 22568

N-methyl-L-glutamate + A + H2O = formaldehyde + L-glutamate + AH2

Direction not assertedBalancedRhea 22572

an N-acyl-L-homoserine lactone + H2O = an N-acyl-L-homoserine + H(+)

Direction not assertedBalance undeterminableRhea 22576

(S)-4-hydroxy-2-oxopentanoate = (2Z)-2-hydroxypenta-2,4-dienoate + H2O

Direction not assertedBalancedRhea 22580

heme b + 2 H(+) = protoporphyrin IX + Fe(2+)

Right to leftBalancedRhea 22584

4-aminobutanal = 1-pyrroline + H2O

Direction not assertedBalancedRhea 22588

(9Z,13S,15Z)-12,13-epoxyoctadeca-9,11,15-trienoate = (9S,13S,15Z)-12-oxophyto-10,15-dienoate

Direction not assertedBalancedRhea 22592

cephalosporin C + H2O = deacetylcephalosporin C + acetate + H(+)

Direction not assertedBalancedRhea 22596

N-acetyl-9-O-acetylneuraminate + H2O = N-acetylneuraminate + acetate + H(+)

Left to rightBalancedRhea 22600

D-mannose = D-fructose

Direction not assertedBalancedRhea 22604

N-succinyl-(2S,6S)-2,6-diaminopimelate + H2O = (2S,6S)-2,6-diaminopimelate + succinate

Direction not assertedBalancedRhea 22608

(3S)-citramalyl-CoA = pyruvate + acetyl-CoA

Direction not assertedBalancedRhea 22612

2 sulochrin + O2 + 2 H(+) = 2 (2R)-bisdechlorogeodin + 2 H2O

Direction not assertedBalancedRhea 22616

L-tryptophan + O2 + H(+) = 3-indoleglycolaldehyde + NH4(+) + CO2

Direction not assertedBalancedRhea 22620

(S)-4-hydroxy-2-oxopentanoate = acetaldehyde + pyruvate

Direction not assertedBalancedRhea 22624

5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate + L-aspartate + ATP = (2S)-2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinate + ADP + phosphate + 2 H(+)

Left to rightBalancedRhea 22628

dCTP + H2O = dCMP + diphosphate + H(+)

Direction not assertedBalancedRhea 22636

sphinganine + NADP(+) = 3-oxosphinganine + NADPH + H(+)

Right to leftBalancedRhea 22640

protopine + reduced [NADPH--hemoprotein reductase] + O2 = 6-hydroxyprotopine + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Direction not assertedBalance undeterminableRhea 22644

holo-[cytochrome c] = apo-[cytochrome c] + heme b

Right to leftBalance undeterminableRhea 22648

2-O-(alpha-D-glucopyranosyl)-sn-glycerol 3-phosphate + H2O = 2-O-(alpha-D-glucopyranosyl)glycerol + phosphate

Direction not assertedBalancedRhea 22652

CDP-ethanolamine + L-serine = L-serine-phosphoethanolamine + CMP + H(+)

Direction not assertedBalancedRhea 22656

holo-[ACP] + a fatty acid + ATP = a fatty acyl-[ACP] + AMP + diphosphate

Direction not assertedBalance undeterminableRhea 22660

2 1-O-(trans-sinapoyl)-beta-D-glucose = 1,2-di-O-sinapoyl beta-D-glucose + D-glucose

Direction not assertedBalancedRhea 22664

2-N,3-O-bis[(3R)-3-hydroxytetradecanoyl]-alpha-D-glucosaminyl 1-phosphate + UDP-2-N,3-O-bis[(3R)-3-hydroxytetradecanoyl]-alpha-D-glucosamine = lipid A disaccharide (E. coli) + UDP + H(+)

Direction not assertedBalancedRhea 22668

2 (2E,6E)-farnesyl diphosphate = presqualene diphosphate + diphosphate

Left to rightBalancedRhea 22672

chlorophyllide a + NADPH + O2 + H(+) = 7(1)-hydroxychlorophyllide a + NADP(+) + H2O

Direction not assertedBalancedRhea 22676

dCTP + H2O + H(+) = dUTP + NH4(+)

Left to rightBalancedRhea 22680

4-amino-L-phenylalanyl-[peptidyl-carrier protein] + AH2 + O2 = (2R)-2-(4-aminophenyl)-L-seryl-[peptidyl-carrier protein] + A + H2O

Direction not assertedBalance undeterminableRhea 22684

D-alanine + O2 + H2O = pyruvate + H2O2 + NH4(+)

Left to rightBalancedRhea 22688

3-hydroxybenzoate + NADH + O2 + H(+) = 2,5-dihydroxybenzoate + NAD(+) + H2O

Direction not assertedBalancedRhea 22692

androst-4-ene-3,17-dione + AH2 + O2 = testololactone + A + H2O

Direction not assertedBalancedRhea 22696

gibberellin A12 aldehyde + reduced [NADPH--hemoprotein reductase] + O2 = gibberellin A12 + oxidized [NADPH--hemoprotein reductase] + H2O + 2 H(+)

Direction not assertedBalance undeterminableRhea 22700

Page 318 of 629