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Reference

Evidence

CompoundsSubstances with curated findings
OutcomesMeasured endpoints
ProteinsTransporters and enzymes
InteractionsPairs that share biology
PapersEvery paper a finding cites
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Chemistry

ReactionsRhea and Human-GEM, by subsystem
ReachWhat a compound can become

Reference layer

PathwaysReactions grouped under one name
ProcessesWhat proteins are annotated as doing
AnatomyTissues, by what is expressed there
Cell typesCells, by what is expressed there
OrganismsSpecies a compound is prepared from
MaterialsSubstances that are not one molecule
AssessmentsRegulatory determinations, transcribed
DiseasesFeatures, genes, and where each sits

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Reference

Evidence

Compounds
Outcomes
Proteins
Interactions
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Articles

Chemistry

Reactions
Reach

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Pathways
Processes
Anatomy
Cell types
Organisms
Materials
Assessments
Diseases

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Catalyst

Computational infrastructure for human biology, built on a provenance-aware knowledge graph. Findings retain their sources; research and simulation are the next layers.

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A reference for what the literature reports. Not medical advice.

© 2026 CatalystPrivacy TermsReference data under the licences listed on the attribution page.

Index

Reactions

Reactions from Rhea and Human-GEM · Reach

reactions in the graph: 31,435

By source

Rhea18,558
Human-GEM12,877

Inferred

Reference data, not a finding. Evidence key

Filter reactions by equationSource

Reactions

15,801–15,850 of 31,435, by identifier

N-carbamoylputrescine + H2O + 2 H(+) = putrescine + NH4(+) + CO2
Direction not assertedBalancedRhea 22284
an oligoglycosyl-(1->4)-beta-D-glucosyl-(1<->1)-ceramide + H2O = an oligoglycosyl-(1->4)-D-glucose + an N-acyl-sphingoid base
Direction not assertedBalance undeterminableRhea 22288
benzoyl-CoA + 3 malonyl-CoA + 3 H(+) = biphenyl-3,5-diol + 4 CO2 + 4 CoA
Direction not assertedBalancedRhea 22292
2 (2E,6E,10E)-geranylgeranyl diphosphate = (1R,2R,3R)-prephytoene diphosphate + diphosphate
Direction not assertedBalancedRhea 22296
a flavonol + UDP-alpha-D-glucose = a flavonol 3-O-beta-D-glucoside + UDP + H(+)
Direction not assertedBalance undeterminableRhea 22300
keto-D-fructose + a ubiquinone = 5-dehydro-D-fructose + a ubiquinol
Direction not assertedBalance undeterminableRhea 22304

xylitol + O2 = D-xylose + H2O2

Direction not assertedBalancedRhea 22308

5-(methylsulfanyl)-D-ribose + ATP = 5-(methylsulfanyl)-alpha-D-ribose 1-phosphate + ADP + H(+)

Direction not assertedBalancedRhea 22312

13-hydroxydocosanoate + UDP-alpha-D-glucose = 13-(beta-D-glucosyloxy)docosanoate + UDP + H(+)

Direction not assertedBalancedRhea 22316

2 alpha-D-glucose 1-phosphate + H2O = D-maltose + 2 phosphate

Direction not assertedBalancedRhea 22320

leukotriene A4 + H2O = leukotriene B4

Left to rightBalancedRhea 22324

4-methyl-5-(2-phosphooxyethyl)-thiazole + 4-amino-2-methyl-5-(diphosphooxymethyl)pyrimidine + H(+) = thiamine phosphate + diphosphate

Direction not assertedBalancedRhea 22328

(3R)-citramalate = 2-methylmaleate + H2O

Direction not assertedBalancedRhea 22332

L-homocysteine + glycine betaine = N,N-dimethylglycine + L-methionine

Left to rightBalancedRhea 22336

3-hydroxybenzyl alcohol + NADP(+) = 3-hydroxybenzaldehyde + NADPH + H(+)

Direction not assertedBalancedRhea 22340

(2R)-3-(3,4-dihydroxyphenyl)lactate + (E)-caffeoyl-CoA = (R)-rosmarinate + CoA

Direction not assertedBalancedRhea 22344

4-aminoimidazole + H2O + H(+) = imidazol-4-one + NH4(+)

Direction not assertedBalancedRhea 22348

L-lysine + H(+) = cadaverine + CO2

Direction not assertedBalancedRhea 22352

oxaloacetate + diphosphate = phosphoenolpyruvate + CO2 + phosphate

Direction not assertedBalancedRhea 22356

D-glutamate = 5-oxo-D-proline + H2O

Direction not assertedBalancedRhea 22360

L-quinate + NAD(+) = 3-dehydroquinate + NADH + H(+)

Direction not assertedBalancedRhea 22364

L-ribulose 5-phosphate = D-xylulose 5-phosphate

Direction not assertedBalancedRhea 22368

propionate 3-nitronate + O2 + H2O = 3-oxopropanoate + nitrite + H2O2 + H(+)

Direction not assertedBalancedRhea 22372

uridine(38/39/40) in tRNA = pseudouridine(38/39/40) in tRNA

Left to rightBalancedRhea 22376

[(1->4)-alpha-D-galacturonosyl methyl ester](n) + n H2O = [(1->4)-alpha-D-galacturonosyl](n) + n methanol + n H(+)

Direction not assertedBalance undeterminableRhea 22380

5-diphospho-1D-myo-inositol 1,2,3,4,6-pentakisphosphate + H2O = 1D-myo-inositol hexakisphosphate + phosphate + H(+)

Left to rightBalancedRhea 22384

N(6)-hydroxy-L-lysine + acetyl-CoA = N(6)-acetyl-N(6)-hydroxy-L-lysine + CoA

Direction not assertedBalancedRhea 22388

1-(4-hydroxy-3-methoxyphenyl)-2-(2-methoxyphenoxy)propane-1,3-diol + H2O2 = guaiacol + vanillin + glycolaldehyde + H2O

Direction not assertedBalancedRhea 22396

androstan-3alpha,17beta-diol + NAD(+) = 17beta-hydroxyandrostanone + NADH + H(+)

Direction not assertedBalancedRhea 22400

beta-D-galacturonate + NAD(+) = D-galactaro-1,5-lactone + NADH + H(+)

Direction not assertedBalancedRhea 22404

isopentenyl diphosphate + dimethylallyl diphosphate = (2E)-geranyl diphosphate + diphosphate

Direction not assertedBalancedRhea 22408

3,4-dihydroxybenzoate + H(+) = catechol + CO2

Direction not assertedBalancedRhea 22416

cis,trans-4-hydroxymuconate semialdehyde + NAD(+) + H2O = maleylacetate + NADH + 2 H(+)

Direction not assertedBalancedRhea 22420

an S-alkyl-L-cysteine + H2O = an alkyl thiol + pyruvate + NH4(+)

Direction not assertedBalance undeterminableRhea 22424

N-[(5S)-5-amino-5-carboxypentanoyl]-L-cysteinyl-D-valine + O2 = isopenicillin N + 2 H2O

Direction not assertedBalancedRhea 22428

a (3S)-3-hydroxyacyl-CoA + NAD(+) = a 3-oxoacyl-CoA + NADH + H(+)

ReversibleBalance undeterminableRhea 22432

(2E,6E)-farnesyl diphosphate + H2O = (1E,4S,5E,7R)-germacra-1(10),5-dien-11-ol + diphosphate

Direction not assertedBalancedRhea 22436

UDP-N-acetyl-alpha-D-glucosamine + UDP-alpha-D-galactose = UDP-N-acetyl-6-(alpha-D-galactose-1-phospho)-alpha-D-glucosamine + UMP + H(+)

Direction not assertedBalancedRhea 22440

(E)-coniferol + NADP(+) = (E)-coniferaldehyde + NADPH + H(+)

Direction not assertedBalancedRhea 22444

pseudouridine + ATP = psi-UMP + ADP + H(+)

Direction not assertedBalancedRhea 22448

[phosphate](n+1) + n H2O = (n+1) phosphate + n H(+)

Direction not assertedBalance undeterminableRhea 22452

creatine + H2O = sarcosine + urea

Direction not assertedBalancedRhea 22456

a 2,3-saturated acyl-CoA + NADP(+) = a 2,3-dehydroacyl-CoA + NADPH + H(+)

Direction not assertedBalance undeterminableRhea 22460

L-tyrosine + reduced [NADPH--hemoprotein reductase] + O2 = N-hydroxy-L-tyrosine + oxidized [NADPH--hemoprotein reductase] + H2O + 2 H(+)

Direction not assertedBalance undeterminableRhea 22464

GTP + 3 H2O = 2-amino-5-formylamino-6-(5-phospho-D-ribosylamino)pyrimidin-4(3H)-one + 2 phosphate + 2 H(+)

Direction not assertedBalancedRhea 22468

(R)-pantetheine + ATP = (R)-4'-phosphopantetheine + ADP + H(+)

Direction not assertedBalancedRhea 22472

4-(hydroxyamino)quinoline N-oxide + 2 NADP(+) + H2O = 4-nitroquinoline N-oxide + 2 NADPH + 2 H(+)

Direction not assertedBalancedRhea 22476

4-(hydroxyamino)quinoline N-oxide + 2 NAD(+) + H2O = 4-nitroquinoline N-oxide + 2 NADH + 2 H(+)

Direction not assertedBalancedRhea 22480

P(1),P(4)-bis(5'-guanosyl) tetraphosphate + H2O = GMP + GTP + 2 H(+)

Direction not assertedBalancedRhea 22484

S-(hydroxymethyl)glutathione = glutathione + formaldehyde

Direction not assertedBalancedRhea 22488

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